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Tuesday, April 19 Scientific Platform Sessions 6:30 a.m.–8:30 a.m. Scientific Platform Sessions S27: Movement Disorders. Essential Tremor and Tardive Dyskinesia 6:30 a.m. S27.001 Open-Label Extension of KINECT: A Phase 2 Study of Valbenazine (NBI-98854) for Tardive Dyskinesia — Mohammed Bari, Raj Shiwach, Roland Jimenez, Scott Siegert, Christopher O'Brien 6:45 a.m. S27.002 Botulinum Toxin Treatment of Essential Tremor - A Customized Approach — Rezvan Rostami, Christopher Chow, Diana Richardson, Bahman Jabbari, Duarte Machado 7:00 a.m. S27.003 Pathogenic PARK2 Variants in Early- Onset Essential Tremor Families — Lorraine Clark, Nora Hernandez, Ruth Ottman, Elan Louis 7:15 a.m. S27.004 A Multi-Center, Randomized, Controlled Trial of Unilateral Focused Ultrasound Thalamotomy for Essential Tremor —William Ondo, Jeff Elias 7:30 a.m. S27.005 Closing the Loop in Deep Brain Stimulation: A Responsive Treatment for Essential Tremor —Enrico Opri, Jonathan Shute, Rene Molina, Kelly Foote, Michael Okun, Aysegul Gunduz 7:45 a.m. S27.006 Exploring Essential Tremor: Results from a Large Online Survey —Phaedra Dowell, Rajesh Pahwa, Kelly Lyons 8:00 a.m. S27.007 A Phase 2 Study of Valbenazine (NBI-98854) for Treatment of Tardive Dyskinesia: KINECT 2 —Stewart Factor, Robert Hauser, Daniel Mandri, Julio Castro-Gayol, Roland Jimenez, Scott Siegert, Christopher O'Brien 8:15 a.m. S27.008 Deutetrabenazine Effect on Total Motor Score in Patients with Huntington Disease (First-HD)—Samuel Frank, David Stamler, Victor Sung, Daniel Claassen, Sarah Janicki, Clement Loy, Erin Furr-Stimming, David Oakes, Claudia Testa S28: Clinical Trials and Experimental Therapies in Neuromuscular Diseases 6:30 a.m. S28.001 Eteplirsen, a Phosphorodiamidate Morpholino Oligomer (PMO) for Duchenne Muscular Dystrophy (DMD): Clinical Update and Longitudinal Comparison to External Controls on Six-Minute Walk Test (6MWT) —J. Mendell, Nathalie Goemans, Louise Rodino-Klapac, Zarife Sahenk, Linda Lowes, Lindsay Alfano, K Berry, E Peterson, S Lewis, Kim Shontz, J Shao, P Duda, C Donoghue, F Schnell, J Dworzak, Bruce Wentworth, E. Kaye, E Mercuri, DMD Italian Network 6:45 a.m. S28.002 Results of North Star Ambulatory Assessments (NSAA) in the Phase 3 Ataluren Confirmatory Trial in Patients with Nonsense Mutation Duchenne Muscular Dystrophy (ACT DMD) — Katharine Bushby, Jan Kirschner, Xiaohui Luo, Gary Elfring, Hans Kroger, Peter Riebling, Tuyen Ong, Robert Spiegel, Stuart Peltz, Francesco Muntoni 7:00 a.m. S28.003 Thymectomy in Non-thymomatous Myasthenia Gravis: Results from MGTX, a Randomized, Controlled Trial —Gary Cutter, Henry Kaminski, Gil Wolfe, Immaculada Aban, On behalf of the MGTX Trial Research Group 7:15 a.m. S28.004 Intravenous Trehalose Improves Dysphagia and Muscle Function in Oculopharyngeal Muscular Dystrophy (OPMD): Preliminary Results of 24 Weeks Open Label Phase 2 Trial — Zohar Argov, Irit Gliko-Kabir, Bernard Brais, Yoseph Caraco, Dalia Megiddo 7:30 a.m. S28.005 Genome Therapy of Myotonic Dystrophy Type 1 IPS Cells for Development of Autologous Stem Cell Therapy —Guangbin Xia, Yuanzheng Gao, Xiuming Guo, Katherine Santostefano, Karen McFarland, Naohiro Terada, Tetsuo Ashizawa 7:45 a.m. S28.006 Effect of Deflazacort and Prednisone Versus Placebo on Muscle Strength in Boys with Duchenne Muscular Dystrophy Who Have Lost Ambulation: Results from the Deflazacort Clinical Trial Program —Timothy Cunniff, Stephen Wanaski, Jordan Dubow, James Meyer 8:00 a.m. S28.007 Antiiflammatory and Neuroprotective Role of Fingolimod in Experimental Autoimmune Neuritis in Lewis Rats — Bjoern Ambrosius, Kalliopi Pitarokoili, Lisa Schrewe, Ralf Gold 8:15 a.m. S28.008 Electrical Impedance Myography and Quantitative Ultrasound Detect Steroid Related Improvements in Duchenne Muscular Dystrophy —Seward Rutkove, Craig Zaidman, Jim Wu, Amy Pasternak, Lavanya Madabusi, Heather Szelag, Tim Harrington, Adam Pacheck, Sung Yim, Kush Kapur, Basil Darras S29: Pediatric Multiple Sclerosis 6:30 a.m. S29.001 First Genome-Wide Analysis in Pediatric Multiple Sclerosis (MS) Confirms a Role for Adult MS Risk Variants and Reveals New Candidates —Lisa Barcellos, Xiaorong Shao, Brooke Rhead, Milena Gianfrancesco, Jennifer Graves, Amy Waldman, Timothy Lotze, Teri Schreiner, Anita Belman, Benjamin Greenberg, Bianca Weinstock-Guttman, Gregory Aaen, Jan- Mendelt Tillema, Janace Hart, Jayne Ness, Yolanda Harris, Jennifer Rubin, Meghan Candee, Lauren Krupp, Mark Gorman, Leslie Benson, Moses Rodriguez, Tanuja Chitnis, Soe Mar, Adeline Vanderver, Ilana Kahn, John Rose, Shelly Roalstad, Charlie Casper, Ling Shen, Hong Quach, Catherine Metayer, Cathy Schaefer, Emmanuelle Waubant 6:45 a.m. S29.002 Pediatric Radiologically Isolated Syndrome: Clinical and Radiological Outcomes —Naila Makhani, Christine Lebrun Frenay, Aksel Siva, Clarisse Carra-Dalliere, Jerome De Seze, Francoise Durand Dubief, Orhun Kantarci, Megan Langille, Jean Pelletier, Juan Ignacio Rojas, Teri Schreiner, Mar Tintore, Ugur Uygunoglu, Darin Okuda, Daniel Pelletier 7:00 a.m. S29.003 Effect of Obesity and Puberty on Risk and Age at Onset of Pediatric MS — Tanuja Chitnis, Jennifer Graves, Bianca Weinstock-Guttman, Anita Belman, Cody Olsen, Madhusmita Misra, Gregory Aaen, Leslie Benson, Meghan Candee, Mark Gorman, Benjamin Greenberg, Timothy Lotze, Jayne Ness, Moses Rodriguez, John Rose, Jennifer Rubin, Teri Schreiner, Jan-Mendelt Tillema, Charlie Casper, Emmanuelle Waubant 7:15 a.m. S29.004 Demographic and Clinical Characteristics of 490 Children and Adolescents with Multiple Sclerosis (MS): US Network of Pediatric MS Centers’ Experience —Anita Belman, Lauren Krupp, Cody Olsen, John Rose, Gregory Aaen, Leslie Benson, Tanuja Chitnis, Mark Gorman, Jennifer Graves, Yolanda Harris, Timothy Lotze, Jayne Ness, Shelly Roalstad, Moses Rodriguez, Jan- Mendelt Tillema, Emmanuelle Waubant, Bianca Weinstock-Guttman, Charlie Casper 7:30 a.m. S29.005 Maternal Illness in Pregnancy and Perinatal Exposure to Pesticides Are Associated with Risk for Pediatric Onset MS —Jennifer Graves, Tanuja Chitnis, Bianca Weinstock-Guttman, Jennifer Rubin, Aaron Zelikovitch, Bardia Nourbakhsh, Timothy Simmons, Charlie Casper, Emmanuelle Waubant 7:45 a.m. S29.006 Dietary Factors and Risk of Pediatric Multiple Sclerosis —Julia Pakpoor, Brandon Seminatore, Jennifer Graves, Teri Schreiner, Amy Waldman, Timothy Lotze, Anita Belman, Benjamin Greenberg, Bianca Weinstock-Guttman, Gregory Aaen, Jan- Mendelt Tillema, Janace Hart, Jayne Ness, Yvonne Harris, Jennifer Rubin, Meghan Candee, Lauren Krupp, Mark Gorman, Leslie Benson, Moses Rodriguez, Tanuja Chitnis, Soe Mar, Ilana Kahn, John Rose, Shelly Roalstad, Michael Waltz, Charlie Casper, Emmanuelle Waubant 8:00 a.m. S29.007 The Causal Effect of Serum Vitamin D Levels on Pediatric Multiple Sclerosis: A Mendelian Randomization Study — Brooke Rhead, Milena Gianfrancesco, Xiaorong Shao, Jennifer Graves, Amy Waldman, Timothy Lotze, Teri Schreiner, Anita Belman, Benjamin Greenberg, Bianca Weinstock-Guttman, Gregory Aaen, Jan- Mendelt Tillema, Janace Hart, Jayne Ness, Yolanda Harris, Jennifer Rubin, Meghan Candee, Lauren Krupp, Mark Gorman, Leslie Benson, Moses Rodriguez, Tanuja Chitnis, Soe Mar, Ilana Kahn, John Rose, Shelly Roalstad, Charlie Casper, Ling Shen, Hong Quach, Catherine Metayer, Cathy Schaefer, Lisa Barcellos, Emmanuelle Waubant 8:15 a.m. S29.008 Associations Between Immune Markers and Gut Microbiota in Pediatric Multiple Sclerosis and Controls —Helen Tremlett, Douglas Fadrosh, Ali Farqui, Janace Hart, Shelly Roalstad, Jennifer Graves, Collin Spencer, Susan Lynch, Scott Zamvil, Emmanuelle Waubant 90 2016 AAN Annual Meeting Abstract Listing
Meeting Schedule 6:30 a.m.–8:30 a.m. S27 Movement Disorders: Essential Tremor and Tardive Dyskinesia S28 Clinical Trials and Experimental Therapies in Neuromuscular Diseases S29 Pediatric Multiple Sclerosis C127 S Sleep Across the Lifecycle: What Neurologists Need to Know Director: Michael J. Howell, MD, FAAN, Minneapolis, MN C128 Management of Migraine and Psychiatric Comorbidities Director: Mia T. Minen, MD, New York, NY C129 Neurologic Intensive Care I Director: Alejandro A. Rabinstein, MD, FAAN, Rochester, MN C130 Neuro-ophthalmology I Director: Nancy J. Newman, MD, FAAN, Atlanta, GA C131 Practical Legal Issues for Neurologists Director: Daniel G. Larriviere, MD, JD, FAAN, New Orleans, LA C132 Balance and Gait Disorders Director: Bastiaan Roelof Bloem, MD, PhD, Nijmegen, The Netherlands C133 Mild Cognitive Impairment: Implications for Clinicians Director: David J. Gill, MD, Rochester, NY C134 Emerging Therapies in Epilepsy Director: Carl W. Bazil, MD, PhD, FAAN, New York, NY C135 Neuro Flash: Child Neurology Director: Erika Fullwood Augustine, MD, FAAN, Rochester, NY C136 Controversies in Stroke Therapy Director: Steven R. Messe, MD, FAAN, FAHA, Philadelphia, PA 7:00 a.m.–7:45 a.m. Health & Wellness Yoga Instructor: Sarah Bird Nelson, JD, RYT 200, Minneapolis, MN 8:30 a.m.–7:00 p.m. P4 Poster Session IV . . . . . . . . . . . . . 92 9:00 a.m.–11:30 a.m. Frontiers in Neuroscience Plenary Session. . .101 11:00 a.m.–4:00 p.m. Exhibit Hall 1:00 p.m.–2:00 p.m. I New Approaches to Biosensing and Biomarkers for the Management of Neurological Disease Director: John David Hixson, MD, San Francisco, CA Health & Wellness Oasis in the Overwhelm Director: Dina Kruzansky Markind, CPCC, Danbury, CT Get Essential Career Advice at Navigating Your Career: All Aboard! Friday, April 15–Thursday, April 21: 7:00 a.m.–5:30 p.m. Location: West Level 1 Get the information you need on how to choose the best career option, how to succeed in your current career, or how to make a career transition—this exciting new Experiential Learning Area at the 2016 AAN Annual Meeting has something for everyone, including medical students, residents, fellows, junior faculty, senior faculty, and advanced practice providers. Topics include: }} Writing and Reviewing for Neurology ® Resident and Fellow Section }} Conflict Resolution: Finding Common Ground }} Giving and Getting Great Feedback }} The Neurohospitalist Model }} Choosing Neurohospitalist Career }} Interviewing Skills }} Interviewing Skills: Negotiation }} Career Stories: Nuts and Bolts of Academic Leadership— Strategies I have Learned in my Career }} Career Stories }} Private Practice to Employed Model }} Being a Great Chief Resident }} Research in Residency: How to Choose the Right Project }} Resident Wellness & Burnout: What we Know and What we Don’t }} Measuring Success: Quality Improvement 101 Learn more at AAN.com/view/NavigatingYourCareer . Tue· April 19 Fast and easy registration · AAN.com/view/AM16 91
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Additional Information INTRODUCTION
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OVERVIEWS Mon April 18 Tue April 19
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Schedule Planning Forms Use the con
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