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Monday, April 18<br />
Scientific Platform Sessions<br />
3:30 p.m.–5:30 p.m. Scientific Platform Sessions<br />
S24: Clinical Outcomes and<br />
Treatment Strategies in<br />
Multiple Sclerosis<br />
3:30 p.m. S24.001<br />
Predicting the End of Symptomatic<br />
Relapses and Disease Modifying<br />
Treatment Use Decisions in Progressive<br />
Multiple Sclerosis —Martina Novotna,<br />
Brittani Conway, Burcu Zeydan, M. Paz<br />
Soldan, Nuhad Abou Zeid, Nilufer Kale,<br />
Melih Tutuncu, Orhun Kantarci<br />
3:45 p.m. S24.002<br />
Can We Stop Immunomodulatory<br />
Treatment in Secondary Progressive<br />
MS? —Julien Bonenfant, Veronique<br />
Deburghgraeve, Emmanuelle Le Page,<br />
Gilles Edan, Anne Kerbrat, Bajeux Emma<br />
4:00 p.m. S24.003<br />
Switch Strategies in RRMS: A Real-Life<br />
Multi Center Study —Francesco Sacc,<br />
Alessio Signori, Giorgia Teresa Maniscalco,<br />
Roberta Lanzillo, Salvatore Lo Fermo,<br />
Pietro Annovazzi, Luca Prosperini, Eleonora<br />
Cocco, Simona Bonavita, Valentina Torri<br />
Clerici, Alice Laroni, Anna Maria Repice,<br />
Ignazio Roberto Zarbo, Cerqua Raffaella,<br />
Alessia Di Sapio, Simona Pontecorvo,<br />
Marinella Clerico, Luigi Lavorgna, Caterina<br />
Barrillà, Cinzia Cordioli, Fabio Gallo, Maria<br />
Pia Sormani<br />
4:15 p.m. S24.004<br />
Comparison of Fingolimod and Dimethyl<br />
Fumarate in the Treatment of Multiple<br />
Sclerosis: Two Year Experience —<br />
Brandi Vollmer, Kavita Nair, Stefan Sillau,<br />
John Corboy, Timothy Vollmer, Enrique<br />
Alvarez<br />
4:30 p.m. S24.005<br />
Interferon-Beta Exposure During First<br />
Trimester in Women with Multiple<br />
Sclerosis - A Prospective Cohort Study<br />
from the German Multiple Sclerosis<br />
and Pregnancy Registry —Sandra Thiel,<br />
Sylvia Menck, Birte Elias-Hamp, Ralf Gold,<br />
Kerstin Hellwig<br />
4:45 p.m. S24.006<br />
Pregnancy and Fetal Outcomes After<br />
In Utero Exposure to Natalizumab in<br />
Patients with Multiple Sclerosis: A<br />
Prospective, Nation-Wide, Controlled<br />
Study —Marta Giannini, Emilio Portaccio,<br />
Bahia Hakiki, Pasto' Luisa, Lorenzo<br />
Razzolini, Righini Isabella, Carla Tortorella,<br />
Maria Trojano, Eleonora Cocco, Maurizio<br />
Melis, Marrosu Maria Giovanna, Valeria<br />
Di Tommaso, Deborah Farina, Alessandra<br />
Lugaresi, Pietro Annovazzi, Angelo Ghezzi,<br />
Claudio Gasperini, Alfonso Iudice, Roberta<br />
Fantozzi, Paolo Bellantonio, Silvia Messina,<br />
Francesco Patti, Chiavazza Carlotta, Paola<br />
Cavalla, Alessandra Protti, Rocco Totaro,<br />
Carlo Pozzilli, Laura De Giglio, Antonio<br />
Uccelli, Arianna Sartori, Antonio Bosco,<br />
Roberta Lanzillo, Vincenzo Brescia Morra,<br />
Maria Pia Amato<br />
5:00 p.m. S24.007<br />
Age Related Multiple Sclerosis<br />
Severity Score: Disability Ranked by<br />
Age —Ali Manouchehrinia, Westerlind<br />
Helga, Elaine Kingwell, Feng Zhu, Robert<br />
Carruthers, Ryan Ramanujam, Ban Maria,<br />
Anna Glaser, Stephen Sawcer, Helen<br />
Tremlett, Jan Hillert<br />
5:15 p.m. S24.008<br />
Pregnancy Outcomes in Patients with<br />
RRMS Who Received Alemtuzumab in<br />
the Clinical Development Program —<br />
Jiwon Oh, Anat Achiron, Christina<br />
Chambers, Edward Fox, Pamela McCombe,<br />
Susana Otero, David Margolin, Linda<br />
Kasten, D Alastair Compston<br />
S25: Movement Disorders:<br />
Huntington's Disease<br />
3:30 p.m. Presentation of the<br />
Movement Disorders Research<br />
Award<br />
Sponsored by the American Academy of<br />
Neurology and the Parkinson’s Disease<br />
Foundation through an endowment.<br />
Recipient:<br />
Susan B. Bressman, MD, FAAN<br />
New York, NY<br />
4:00 p.m. S25.003<br />
Intermediate CAG Repeats in<br />
Huntington´s Disease. A Longitudinal<br />
Analysis of the European Huntington´s<br />
Disease Network REGISTRY Cohort —<br />
Esther Cubo, Maria Antonia Ramos-Arroyo,<br />
Saul Martinez-Horta, Asunción Martinez-<br />
Descalls, Cecilia Gil-Polo<br />
4:15 p.m. S25.004<br />
PRE-CELL: Clinical and Novel Biomarker<br />
Measures of Disease Progression in<br />
a Lead-In-Observational Study for a<br />
Planned Phase 1 Trial of Genetically-<br />
Modified Mesenchymal Stem Cells<br />
Over-Expressing BDNF in Patients with<br />
Huntington’s Disease —Vicki Wheelock,<br />
Teresa Tempkin, Alexandra Duffy, Amanda<br />
Martin, Lisa Mooney, Ashok Dayananthan,<br />
Lorin Scher, Sarah Farias, David Swadell,<br />
Charles DeCarli, James Brunberg, Chin-<br />
Shang Li, Yu Liu, Mark Yarborough, Julie<br />
Stout, miriam Moscovitch-Lopatin, Steven<br />
Hersch, Kyle Fink, Geralyn Annett, Jan<br />
Nolta<br />
4:30 p.m. S25.005<br />
Enroll-HD: A Global Clinical Research<br />
Platform for Huntington’s Disease —<br />
Tiago Mestre, Cheryl Fitzer-Attas, Joseph<br />
Giuliano, Bernhard Landwehrmeyer,<br />
Cristina Sampaio<br />
4:45 p.m. S25.006<br />
Rating Swallowing Function in Patients<br />
with Huntington Disease Enrolled in<br />
the First-HD Study —Daniel Claassen,<br />
Samuel Frank, David Stamler, Victor Sung,<br />
Sarah Janicki, David Oakes, Christina<br />
Vaughan, Claudia Testa<br />
5:00 p.m. S25.007<br />
Mesenchymal Stem Cells Engineered<br />
to Overexpress Brain-Derived<br />
Neurotrophic Factor As a Proposed<br />
Therapeutic for Huntington’s<br />
Disease —Vicki Wheelock, Kari Pollock,<br />
Heather Dahlenberg, Hayley Nelson, Kyle<br />
Fink, Whitney Cary, Kyle Hendrix, Geralyn<br />
Annett, Audrey Torrest, Peter Deng, Josh<br />
Gutierrez, Catherine Nacy, Karen Pepper,<br />
Stefanos Kalomoiris, Johnathon Anderson,<br />
Jeannine McGee, William Gruenloh, Brian<br />
Fury, Gerhard Bauer, Alexandra Duffy,<br />
Teresa Tempkin, Jan Nolta<br />
5:15 p.m. S25.008<br />
First-In-Human Stem Cell Trials in<br />
Huntington’s Disease: A Bioethics<br />
Survey —Alexandra Duffy, Teresa<br />
Tempkin, Amanda Martin, Meaghan<br />
O’Keefe, Marsha Michie, Mark Yarborough,<br />
Vicki Wheelock<br />
S26: Headache<br />
3:30 p.m. Presentation of the Harold<br />
Wolff-John Graham: An Award for<br />
Headache/Facial Pain Research<br />
Sponsored by the American Academy<br />
of Neurology and endowed by Endo<br />
Pharmaceuticals.<br />
Recipient:<br />
Catherine Chong, PhD<br />
Phoenix, AZ<br />
3:45 p.m. S26.002<br />
Prevention of Episodic Migraine with<br />
AMG 334, a Human Anti-Calcitonin<br />
Gene-Related Peptide Receptor<br />
Monoclonal Antibody: Phase 2 Study<br />
Results and 52-Week Analysis of<br />
Open-Label Extension —Robert Lenz,<br />
David Dodick, Peter Goadsby, Stephen<br />
Silberstein, Uwe Reuter, Messoud Ashina,<br />
Joel Saper, Roger Cady, Feng Zhang,<br />
Marie-Louise Trotman, Julie Dietrich,<br />
Hong Sun<br />
4:00 p.m. S26.003<br />
Emotional Abuse History and Migraine<br />
Among Young Adults: Results from The<br />
Add Health Dataset —Gretchen Tietjen,<br />
Monita Karmakar, Aliaksander Amialchuk<br />
4:15 p.m. S26.004<br />
Factors Predicting the Response<br />
to the First Epidural Blood Patch<br />
in Spontaneous Intracranial<br />
Hypotension —Jr-Wei Wu, Shu-Shya<br />
Hseu, Jong-Ling Fuh, Jiing-Feng Lirng, Yen-<br />
Feng Wang, Wei-Ta Chen, Shuu-Jiun Wang<br />
4:30 p.m. S26.005<br />
Modifications of Gray Matter Volume<br />
in Migraine Patients Over Four Years: A<br />
Tensor-Based Morphometry Study —<br />
Roberta Messina, Maria Rocca, Bruno<br />
Colombo, Elisabetta Pagani, Andrea Falini,<br />
Giancarlo Comi, Massimo Filippi<br />
4:45 p.m. S26.006<br />
Inflammation and Abnormal Trigeminal<br />
Sensory Processing in Obese Mice —<br />
Ana Recober-Montilla, Heather Rossi<br />
5:00 p.m. S26.007<br />
Peripheral and Central Nervous System<br />
Distribution of a CGRP Neutralizing<br />
Antibody [ 125 I]-LY2951742 in Male<br />
Rats —Michael Johnson, Bernice Ellis,<br />
Deanna Maren, S. Michelle Morin, Victor<br />
Wroblewski, Kirk Johnson<br />
5:15 p.m. S26.008<br />
Delivery Outcomes After Acute<br />
Migraine Treatment in Pregnancy —<br />
Matthew Robbins, Tracy Grossman,<br />
Shravya Govindappagari, Ashlesha Dayal<br />
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86 2016 AAN Annual Meeting Abstract Listing