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Monday, April 18<br />
Integrated Neuroscience Session<br />
I6<br />
1:00 p.m.–5:30 p.m. Integrated Neuroscience Session<br />
S Future Directions and Challenges in Stroke Team Action Therapy (STAT)<br />
This program is offered in partnership with the Stroke and Vascular Neurology Section.<br />
Coordinators: Jeffrey L. Saver, MD, FAAN, and Joseph P. Broderick, MD, FAAN<br />
Program Description: The INS program will present current uncertainties and future directions in acute stroke treatment. The introduction of mobile units with CT scan<br />
capability has the potential to reduce the delay in administration of i.v. thrombolysis by 45 minutes. New devices for mechanical thrombectomy are advancing this form of<br />
therapy and the program will present the diversity of new devices and their optimal therapeutic utilization. Advances in neuroimaging with rapid display of arterial thrombus<br />
location and extent of the penumbra region are extending the range of thrombolysis and improving the outcome of thrombectomy while pushing further out the frontiers of<br />
action. The recent development of comprehensive stroke centers with telestroke technology, mobile units, new neuroimaging capabilities, and increasingly sophisticated<br />
thrombectomy devices are reducing the time-delay for therapeutic action while paradoxically creating geographical disparities in access to care. A call to action is needed to<br />
reduce disparities.<br />
Upon Completion: Participants should be able to identify clinically relevant differences in phenotype or risk factors between males and females with neurological diseases.<br />
Part I<br />
1:00 p.m.–3:00 p.m.<br />
1:00 p.m.–1:10 p.m. Introduction<br />
Jeffrey L. Saver, MD, FAAN, and Joseph P. Broderick, MD, FAAN<br />
1:10 p.m.–1:45 p.m. Invited Speaker<br />
The STAT Ambulance in Motion: Should My Center Get One?<br />
James C. Grotta, MD, FAAN, Houston, TX<br />
1:45 p.m.–1:50 p.m. I6.001 Data Blitz<br />
Gaze Deviation and Acute Stroke Care Strategies —Zaid Mahdi, Anup Kumar<br />
Trikannad Ashwini Kumar, Pratik Bhattacharya, Ramesh Madhavan<br />
1:50 p.m.–1:55 p.m. I6.002 Data Blitz<br />
Comparison of Large Vessel Occlusion Prediction Scores —Toby Gropen, Amelia<br />
Boehme, Sheryl Martin-Schild, Karen Albright, Brian Perrin, Alyana Samai, Sammy<br />
Pishanidar, Nazli Janjua, Steven Levine, Ethan Brandler, Dov Rosenbaum<br />
1:55 p.m.–2:05 p.m. Audience Q&A<br />
2:05 p.m.–2:40 p.m. Invited Speaker<br />
New Developments in Acute Stroke Neuroimaging: Future Directions<br />
Gregory W. Albers, MD, Stanford, CA<br />
2:40 p.m.–2:45 p.m. I6.003 Data Blitz<br />
Variability in Approach to Treatment of Acute Central Retinal Artery Occlusion in<br />
US Teaching Hospitals —Matthew Schrag, Teddy Youn, Morgan Patrylo, Joseph<br />
Schindler, Patrick Lavin, Howard Kirshner, David Greer<br />
2:45 p.m.–2:50 p.m. I6.004 Data Blitz<br />
Intracranial Hemorrhage on Warfarin: Time to Reversal Is of the Essence —<br />
Chandan Mehta, Mathew Jones, Mauricio Ruiz Cuero, Jody Wellwood,<br />
Mohammed Rehman, Panayiotis Mitsias, Panayiotis Varelas<br />
2:50 p.m.–3:00 p.m. Audience Q&A<br />
Guided Poster Rounds<br />
I6.001 Gaze Deviation and Acute<br />
Stroke Care Strategies —Zaid Mahdi,<br />
Anup Kumar Trikannad Ashwini Kumar, Pratik<br />
Bhattacharya, Ramesh Madhavan<br />
I6.002 Comparison of Large Vessel<br />
Occlusion Prediction Scores —Toby<br />
Gropen, Amelia Boehme, Sheryl Martin-<br />
Schild, Karen Albright, Brian Perrin,<br />
Alyana Samai, Sammy Pishanidar, Nazli<br />
Janjua, Steven Levine, Ethan Brandler, Dov<br />
Rosenbaum<br />
I6.003 Variability in Approach to<br />
Treatment of Acute Central Retinal Artery<br />
Occlusion in US Teaching Hospitals —<br />
Matthew Schrag, Teddy Youn, Morgan<br />
Patrylo, Joseph Schindler, Patrick Lavin,<br />
Howard Kirshner, David Greer<br />
I6.004 Intracranial Hemorrhage on<br />
Warfarin: Time to Reversal Is of the<br />
Essence —Chandan Mehta, Mathew<br />
Jones, Mauricio Ruiz Cuero, Jody Wellwood,<br />
Mohammed Rehman, Panayiotis Mitsias,<br />
Panayiotis Varelas<br />
3:00 p.m.–3:30 p.m.<br />
I6.005 Time is Brain: Standardized<br />
Neuro-Interventional Thrombectomy<br />
Protocols Lead to Faster Recanalization<br />
Times —Donald Frei, Lisa Caputo, Kathryn<br />
McCarthy, Kristin Salottolo, David Bar-Or<br />
I6.006 Effect of Annual Hospital<br />
Procedure Volume on Outcomes After<br />
Mechanical Thrombectomy in Acute<br />
Ischemic Stroke Patients: An Analysis<br />
of 13,502 Procedures —Achint Patel,<br />
Harshil Shah, Abhishek Lunagariya, Sanjeeva<br />
Onteddu, Sonal Mehta<br />
I6.007 Arterial Recanalization in the<br />
Golden Hour of IV TPA Administration for<br />
Ischemic Stroke —Rodica Bernatowicz,<br />
Megan Donohue, Muhammad Hussain, Seby<br />
John, Dolora Wisco, Ken Uchino<br />
I6.008 ARTSS-2: Final Results of a<br />
Pilot, Phase IIb, Randomized, Multi-Center<br />
Trial of Argatroban in Combination<br />
with Recombinant Tissue Plasminogen<br />
Activator for Acute Stroke —Andrew<br />
Barreto, Gary Ford, Loren Shen, Chunyan Cai,<br />
Claudia Pedroza, Jon Tyson, Mohammad<br />
Rahbar, James Grotta<br />
I6.009 Early CT Changes in Patients<br />
Admitted for Thrombectomy: Intra- and<br />
Interrater Agreement and Systematic<br />
Review of the Literature —Naim Khoury,<br />
Robert Fahed, Francois Guilbert, Alexandre<br />
Poppe, Nicole Daneault, Behzad Farazin,<br />
Andre Durocher, Sylvain Lanthier, Hayet<br />
Boudjani, Daniel Roy, Alain Weill, Jean-<br />
Christophe Gentric, Andre Lima Batista,<br />
Laurent Letourneau-Guillon, Francois<br />
Bergeron, Marc-Antoine Henry, Tim E.<br />
Darsaut, Jean Raymond<br />
I6.010 Onset to Reperfusion Times<br />
Strongly Determine Clinical Outcome<br />
Across a Wide Range of ASPECTS<br />
Scores in Endovascular Ischemic Stroke<br />
Therapy —Joon-Tae Kim, Mayank Goyal,<br />
Vitor Pereira-Mendes, Alain Bonafe,<br />
Jan Gralla, Reza Jahan, Elad Levy, David<br />
Liebeskind, Jeffrey Saver<br />
Part II<br />
I6.011 Overcoming Barriers to Reduce<br />
Door to Needle Times in Acute Ischemic<br />
Stroke Patients: Field to CT —Spozhmy<br />
Panezai, Florence Chukwuneke, Audrey<br />
Arango, Jaskiran Brar, Joshua Daniel,<br />
Daniel Korya, Siddhart Mehta, Mohammad<br />
Moussavi, Jawad Kirmani<br />
I6.012 Symptomatic Cerebral<br />
Ischemia Associated with Intensive<br />
Blood Pressure Lowering Following Acute<br />
Intracerebral Hemorrhage —Natalie<br />
Organek, Megan Donohue, Lauren Gotterer,<br />
Ken Uchino<br />
I6.013 The DRAGON Score<br />
Predicts Functional Outcomes in Acute<br />
Ischemic Stroke Patients Receiving<br />
Both Intravenous Tissue Plasminogen<br />
Activator (IVtPA) and Endovascular<br />
Therapy —Noorie Pednekar, Jin Li, Richard<br />
Zeman, Rachel Lehrer, Parvinder Kaur, Amrita<br />
Anreja, Emiliya Melkumova, Akira Todo, John<br />
Wainwright, Rivkah Epstein, Ramandeep<br />
Sahni, Stephen Marks, Michael Stiefel<br />
3:30 p.m.–5:30 p.m.<br />
3:30 p.m.–4:05 p.m. Invited Speaker<br />
Mechanical Thrombectomy Devices:<br />
How Many Are There and Where Are We Going?<br />
Johanna Fifi, MD, New York, NY<br />
4:05 p.m.–4:10 p.m. I6.005 Data Blitz<br />
Time is Brain: Standardized Neuro-Interventional Thrombectomy Protocols Lead to<br />
Faster Recanalization Times —Donald Frei, Lisa Caputo, Kathryn McCarthy, Kristin<br />
Salottolo, David Bar-Or<br />
4:10 p.m.–4:15 p.m. I6.006 Data Blitz<br />
Effect of Annual Hospital Procedure Volume on Outcomes After Mechanical<br />
Thrombectomy in Acute Ischemic Stroke Patients: An Analysis of 13,502<br />
Procedures —Achint Patel, Harshil Shah, Abhishek Lunagariya, Sanjeeva Onteddu,<br />
Sonal Mehta<br />
4:15 p.m.–4:25 p.m. Audience Q&A<br />
4:25 p.m.–5:00 p.m. Invited Speaker<br />
Minimizing Geographical Disparities in Acute Stroke Treatment<br />
Dawn O. Kleindorfer, MD, Cincinnati, OH<br />
5:00 p.m.–5:05 p.m. I6.007 Data Blitz<br />
Arterial Recanalization in the Golden Hour of IV TPA Administration for Ischemic<br />
Stroke —Rodica Bernatowicz, Megan Donohue, Muhammad Hussain, Seby John,<br />
Dolora Wisco, Ken Uchino<br />
5:05 p.m.–5:10 p.m. I6.008 Data Blitz<br />
ARTSS-2: Final Results of a Pilot, Phase IIb, Randomized, Multi-Center Trial of<br />
Argatroban in Combination with Recombinant Tissue Plasminogen Activator for<br />
Acute Stroke —Andrew Barreto, Gary Ford, Loren Shen, Chunyan Cai, Claudia<br />
Pedroza, Jon Tyson, Mohammad Rahbar, James Grotta<br />
5:10 p.m.–5:20 p.m. Audience Q&A<br />
5:20 p.m.–5:30 p.m. Conclusion<br />
82 2016 AAN Annual Meeting Abstract Listing