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Monday, April 18<br />

Integrated Neuroscience Session<br />

I6<br />

1:00 p.m.–5:30 p.m. Integrated Neuroscience Session<br />

S Future Directions and Challenges in Stroke Team Action Therapy (STAT)<br />

This program is offered in partnership with the Stroke and Vascular Neurology Section.<br />

Coordinators: Jeffrey L. Saver, MD, FAAN, and Joseph P. Broderick, MD, FAAN<br />

Program Description: The INS program will present current uncertainties and future directions in acute stroke treatment. The introduction of mobile units with CT scan<br />

capability has the potential to reduce the delay in administration of i.v. thrombolysis by 45 minutes. New devices for mechanical thrombectomy are advancing this form of<br />

therapy and the program will present the diversity of new devices and their optimal therapeutic utilization. Advances in neuroimaging with rapid display of arterial thrombus<br />

location and extent of the penumbra region are extending the range of thrombolysis and improving the outcome of thrombectomy while pushing further out the frontiers of<br />

action. The recent development of comprehensive stroke centers with telestroke technology, mobile units, new neuroimaging capabilities, and increasingly sophisticated<br />

thrombectomy devices are reducing the time-delay for therapeutic action while paradoxically creating geographical disparities in access to care. A call to action is needed to<br />

reduce disparities.<br />

Upon Completion: Participants should be able to identify clinically relevant differences in phenotype or risk factors between males and females with neurological diseases.<br />

Part I<br />

1:00 p.m.–3:00 p.m.<br />

1:00 p.m.–1:10 p.m. Introduction<br />

Jeffrey L. Saver, MD, FAAN, and Joseph P. Broderick, MD, FAAN<br />

1:10 p.m.–1:45 p.m. Invited Speaker<br />

The STAT Ambulance in Motion: Should My Center Get One?<br />

James C. Grotta, MD, FAAN, Houston, TX<br />

1:45 p.m.–1:50 p.m. I6.001 Data Blitz<br />

Gaze Deviation and Acute Stroke Care Strategies —Zaid Mahdi, Anup Kumar<br />

Trikannad Ashwini Kumar, Pratik Bhattacharya, Ramesh Madhavan<br />

1:50 p.m.–1:55 p.m. I6.002 Data Blitz<br />

Comparison of Large Vessel Occlusion Prediction Scores —Toby Gropen, Amelia<br />

Boehme, Sheryl Martin-Schild, Karen Albright, Brian Perrin, Alyana Samai, Sammy<br />

Pishanidar, Nazli Janjua, Steven Levine, Ethan Brandler, Dov Rosenbaum<br />

1:55 p.m.–2:05 p.m. Audience Q&A<br />

2:05 p.m.–2:40 p.m. Invited Speaker<br />

New Developments in Acute Stroke Neuroimaging: Future Directions<br />

Gregory W. Albers, MD, Stanford, CA<br />

2:40 p.m.–2:45 p.m. I6.003 Data Blitz<br />

Variability in Approach to Treatment of Acute Central Retinal Artery Occlusion in<br />

US Teaching Hospitals —Matthew Schrag, Teddy Youn, Morgan Patrylo, Joseph<br />

Schindler, Patrick Lavin, Howard Kirshner, David Greer<br />

2:45 p.m.–2:50 p.m. I6.004 Data Blitz<br />

Intracranial Hemorrhage on Warfarin: Time to Reversal Is of the Essence —<br />

Chandan Mehta, Mathew Jones, Mauricio Ruiz Cuero, Jody Wellwood,<br />

Mohammed Rehman, Panayiotis Mitsias, Panayiotis Varelas<br />

2:50 p.m.–3:00 p.m. Audience Q&A<br />

Guided Poster Rounds<br />

I6.001 Gaze Deviation and Acute<br />

Stroke Care Strategies —Zaid Mahdi,<br />

Anup Kumar Trikannad Ashwini Kumar, Pratik<br />

Bhattacharya, Ramesh Madhavan<br />

I6.002 Comparison of Large Vessel<br />

Occlusion Prediction Scores —Toby<br />

Gropen, Amelia Boehme, Sheryl Martin-<br />

Schild, Karen Albright, Brian Perrin,<br />

Alyana Samai, Sammy Pishanidar, Nazli<br />

Janjua, Steven Levine, Ethan Brandler, Dov<br />

Rosenbaum<br />

I6.003 Variability in Approach to<br />

Treatment of Acute Central Retinal Artery<br />

Occlusion in US Teaching Hospitals —<br />

Matthew Schrag, Teddy Youn, Morgan<br />

Patrylo, Joseph Schindler, Patrick Lavin,<br />

Howard Kirshner, David Greer<br />

I6.004 Intracranial Hemorrhage on<br />

Warfarin: Time to Reversal Is of the<br />

Essence —Chandan Mehta, Mathew<br />

Jones, Mauricio Ruiz Cuero, Jody Wellwood,<br />

Mohammed Rehman, Panayiotis Mitsias,<br />

Panayiotis Varelas<br />

3:00 p.m.–3:30 p.m.<br />

I6.005 Time is Brain: Standardized<br />

Neuro-Interventional Thrombectomy<br />

Protocols Lead to Faster Recanalization<br />

Times —Donald Frei, Lisa Caputo, Kathryn<br />

McCarthy, Kristin Salottolo, David Bar-Or<br />

I6.006 Effect of Annual Hospital<br />

Procedure Volume on Outcomes After<br />

Mechanical Thrombectomy in Acute<br />

Ischemic Stroke Patients: An Analysis<br />

of 13,502 Procedures —Achint Patel,<br />

Harshil Shah, Abhishek Lunagariya, Sanjeeva<br />

Onteddu, Sonal Mehta<br />

I6.007 Arterial Recanalization in the<br />

Golden Hour of IV TPA Administration for<br />

Ischemic Stroke —Rodica Bernatowicz,<br />

Megan Donohue, Muhammad Hussain, Seby<br />

John, Dolora Wisco, Ken Uchino<br />

I6.008 ARTSS-2: Final Results of a<br />

Pilot, Phase IIb, Randomized, Multi-Center<br />

Trial of Argatroban in Combination<br />

with Recombinant Tissue Plasminogen<br />

Activator for Acute Stroke —Andrew<br />

Barreto, Gary Ford, Loren Shen, Chunyan Cai,<br />

Claudia Pedroza, Jon Tyson, Mohammad<br />

Rahbar, James Grotta<br />

I6.009 Early CT Changes in Patients<br />

Admitted for Thrombectomy: Intra- and<br />

Interrater Agreement and Systematic<br />

Review of the Literature —Naim Khoury,<br />

Robert Fahed, Francois Guilbert, Alexandre<br />

Poppe, Nicole Daneault, Behzad Farazin,<br />

Andre Durocher, Sylvain Lanthier, Hayet<br />

Boudjani, Daniel Roy, Alain Weill, Jean-<br />

Christophe Gentric, Andre Lima Batista,<br />

Laurent Letourneau-Guillon, Francois<br />

Bergeron, Marc-Antoine Henry, Tim E.<br />

Darsaut, Jean Raymond<br />

I6.010 Onset to Reperfusion Times<br />

Strongly Determine Clinical Outcome<br />

Across a Wide Range of ASPECTS<br />

Scores in Endovascular Ischemic Stroke<br />

Therapy —Joon-Tae Kim, Mayank Goyal,<br />

Vitor Pereira-Mendes, Alain Bonafe,<br />

Jan Gralla, Reza Jahan, Elad Levy, David<br />

Liebeskind, Jeffrey Saver<br />

Part II<br />

I6.011 Overcoming Barriers to Reduce<br />

Door to Needle Times in Acute Ischemic<br />

Stroke Patients: Field to CT —Spozhmy<br />

Panezai, Florence Chukwuneke, Audrey<br />

Arango, Jaskiran Brar, Joshua Daniel,<br />

Daniel Korya, Siddhart Mehta, Mohammad<br />

Moussavi, Jawad Kirmani<br />

I6.012 Symptomatic Cerebral<br />

Ischemia Associated with Intensive<br />

Blood Pressure Lowering Following Acute<br />

Intracerebral Hemorrhage —Natalie<br />

Organek, Megan Donohue, Lauren Gotterer,<br />

Ken Uchino<br />

I6.013 The DRAGON Score<br />

Predicts Functional Outcomes in Acute<br />

Ischemic Stroke Patients Receiving<br />

Both Intravenous Tissue Plasminogen<br />

Activator (IVtPA) and Endovascular<br />

Therapy —Noorie Pednekar, Jin Li, Richard<br />

Zeman, Rachel Lehrer, Parvinder Kaur, Amrita<br />

Anreja, Emiliya Melkumova, Akira Todo, John<br />

Wainwright, Rivkah Epstein, Ramandeep<br />

Sahni, Stephen Marks, Michael Stiefel<br />

3:30 p.m.–5:30 p.m.<br />

3:30 p.m.–4:05 p.m. Invited Speaker<br />

Mechanical Thrombectomy Devices:<br />

How Many Are There and Where Are We Going?<br />

Johanna Fifi, MD, New York, NY<br />

4:05 p.m.–4:10 p.m. I6.005 Data Blitz<br />

Time is Brain: Standardized Neuro-Interventional Thrombectomy Protocols Lead to<br />

Faster Recanalization Times —Donald Frei, Lisa Caputo, Kathryn McCarthy, Kristin<br />

Salottolo, David Bar-Or<br />

4:10 p.m.–4:15 p.m. I6.006 Data Blitz<br />

Effect of Annual Hospital Procedure Volume on Outcomes After Mechanical<br />

Thrombectomy in Acute Ischemic Stroke Patients: An Analysis of 13,502<br />

Procedures —Achint Patel, Harshil Shah, Abhishek Lunagariya, Sanjeeva Onteddu,<br />

Sonal Mehta<br />

4:15 p.m.–4:25 p.m. Audience Q&A<br />

4:25 p.m.–5:00 p.m. Invited Speaker<br />

Minimizing Geographical Disparities in Acute Stroke Treatment<br />

Dawn O. Kleindorfer, MD, Cincinnati, OH<br />

5:00 p.m.–5:05 p.m. I6.007 Data Blitz<br />

Arterial Recanalization in the Golden Hour of IV TPA Administration for Ischemic<br />

Stroke —Rodica Bernatowicz, Megan Donohue, Muhammad Hussain, Seby John,<br />

Dolora Wisco, Ken Uchino<br />

5:05 p.m.–5:10 p.m. I6.008 Data Blitz<br />

ARTSS-2: Final Results of a Pilot, Phase IIb, Randomized, Multi-Center Trial of<br />

Argatroban in Combination with Recombinant Tissue Plasminogen Activator for<br />

Acute Stroke —Andrew Barreto, Gary Ford, Loren Shen, Chunyan Cai, Claudia<br />

Pedroza, Jon Tyson, Mohammad Rahbar, James Grotta<br />

5:10 p.m.–5:20 p.m. Audience Q&A<br />

5:20 p.m.–5:30 p.m. Conclusion<br />

82 2016 AAN Annual Meeting Abstract Listing

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