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Monday, April 18<br />

Poster Session 8:30 a.m.–7:00 p.m.<br />

8:30 a.m.–7:00 p.m. Poster Session<br />

P3 Poster Session III<br />

Presenters Stand by Posters 5:30 p.m.–7:00 p.m.<br />

Poster Discussion Session: MS and CNS Inflammatory Disease<br />

Eight abstracts have been selected for presentation during a poster discussion session. Authors will present a 5-minute<br />

data blitz presentation.<br />

In addition to the regular poster time, authors also have a specific time slot over lunch. Times below are standard<br />

across poster sessions.<br />

Discussion: 11:45 a.m.–11:50 a.m.<br />

P3.001 Myelin Oligodendrocyte<br />

Glycoprotein Antibodies Are Associated<br />

with Bilateral and Recurrent Optic Neuritis<br />

and Have a Distinct Radiological Profile<br />

to Multiple Sclerosis or Aquaporin-4<br />

Antibody-associated Optic Neuritis —<br />

Sudarshini Ramanathan, Kristina Prelog,<br />

Elizabeth Barnes, Esther Tantsis, Stephen<br />

Reddel, Andrew Henderson, Ostoja Vucic,<br />

Mark Gorman, Leslie Benson, Gulay Alper,<br />

Catherine Riney, Michael Barnett, John<br />

Parratt, Todd Hardy, Richard Leventer, Vera<br />

Merheb, Margherita Nosadini, Victor Fung,<br />

Fabienne Brilot, Russell Dale<br />

Discussion: 11:50 a.m.–11:55 a.m.<br />

P3.002 Lifetime Sun Exposure and<br />

the Risk of Multiple Sclerosis in Blacks<br />

and Hispanics —Annette Langer-Gould, Lie<br />

Chen, Edlin Gonzales, Christopher Schroeder,<br />

Anny Xiang, Lisa Barcellos, Robyn Lucas<br />

Discussion: 11:55 a.m.–12:00 p.m.<br />

P3.003 Epidemiology of Aquaporin-4<br />

Autoimmunity and Neuromyelitis<br />

Optica Spectrum: A Comparison of Two<br />

Ethnically Divergent Populations —Eoin<br />

Flanagan, Philippe Cabre, Brian Weinshenker,<br />

JenniferSt. Sauver, Masoud Majed, Vanda<br />

Lennon, Claudia Lucchinetti, Andrew McKeon,<br />

Dean Wingerchuk, Jayawant Mandrekar,<br />

Debra Jacobson, Jessica Sagen, John<br />

Schmeling, James Fryer, Marcelo Matiello,<br />

Nilifur Kale, Angala Borders Robinson, Sean<br />

Pittock<br />

Discussion: 12:00 p.m.–12:05 p.m.<br />

P3.004 Novel Findings in Anti-GABAa<br />

Receptor Encephalitis —Marianna Spatola,<br />

Mar Petit-Pedrol, Myrna Rosenfeld, Francesc<br />

Graus, Josep Dalmau<br />

Discussion: 12:05 p.m.–12:10 p.m.<br />

P3.005 Multiple Sclerosis White<br />

Matter Demyelination and Remyelination<br />

Using T1-, T2- and T2*-Weighted Images:<br />

A Post Mortem Validation Study at<br />

7.0 Tesla —Michael Bradshaw, Assunta<br />

Dal-Bianco, Simon Hametner, Siddharama<br />

Pawate, Subramaniam Sriram, Seth Smith,<br />

John Gore, Brian Welch, Hans Lassmann,<br />

Francesca Bagnato<br />

Discussion: 12:10 p.m.–12:15 p.m.<br />

P3.006 Vitamin D Supplementation<br />

Reduces Markers of Oxidative Stress<br />

Measured by Untargeted Metabolomics<br />

in Healthy Controls but Not in Multiple<br />

Sclerosis Patients —Pavan Bhargava,<br />

Kathryn Fitzgerald, Sonya Steele, Sandra<br />

Cassard, Emmanuelle Waubant, Peter<br />

Calabresi, Ellen Mowry<br />

Discussion: 12:15 p.m.–12:20 p.m.<br />

P3.007 The Role of Gut Immunity in<br />

Multiple Sclerosis Patients —Vittorio<br />

Martinelli, Maria Josè Messina, Mariani<br />

Alberto, Ilaria Cosorich, Gloria Dalla Costa,<br />

Gloria Dalla Costa, Mariaemma Rodegher,<br />

Giancarlo Comi, Marika Falcone<br />

Discussion: 12:20 p.m.–12:25 p.m.<br />

P3.008 Progressive Solitary Sclerosis:<br />

Insidious Motor Impairment Localized<br />

to an Isolated CNS Demyelinating<br />

Lesion —Mark Keegan, Timothy Kaufmann,<br />

Brian Weinshenker, Orhun Kantarci, William<br />

Schmalstieg, M. Paz Soldan, Eoin Flanagan<br />

e-Poster Session: MS and CNS Inflammatory Disease<br />

Ten e-posters in six neurologic topics have been selected for on-site, interactive display. e-Posters will be grouped in a separate<br />

area where attendees are invited to explore more deeply through touch screen displays.<br />

P3.009 Contrasting In Situ and In Vitro<br />

Expression of MiR-155 and MiR-146a<br />

in Astrocytes in Context of Multiple<br />

Sclerosis (MS)—Vijayaraghava Rao, Samuel<br />

Ludwin, Shih-Chieh Fuh, Marthe Minderman,<br />

Robin Sawaya, Craig Moore, Ming-Kai Ho,<br />

Barry Bedell, Jack Antel<br />

P3.010 Dimethyl Fumarate Is Well<br />

Tolerated in a Small Cohort of Pediatric-<br />

Onset Multiple Sclerosis Patients —Ian<br />

Rossman, Manikum Moodley, Mary Rensel<br />

P3.011 Movement Measurements<br />

At Home for Multiple Sclerosis: Walking<br />

Speed and Cane Usage Measured by a<br />

Novel Infrared Sensor —Victoria M. Smith,<br />

Jonathan Varsanik, Kevin Patel, Wendy<br />

Gabel, Glenn Phillips, Zebadiah Kimmel, Eric<br />

Klawiter<br />

P3.012 Racial Variations in Mean<br />

Serum Vitamin A (Retinoic Acid) Levels in<br />

Multiple Sclerosis Patients with Normal/<br />

Corrected Vitamin D Levels —Bijal Mehta,<br />

Kristen Berube<br />

P3.013 Automatic Measurement of<br />

Optic Nerve Atrophy in Multiple Sclerosis<br />

Patients with and Without Optic Neuritis<br />

in MRI —Robert Harrigan, Bennett Landman,<br />

Louise Mawn, Siddharama Pawate, Seth Smith<br />

P3.014 MS Arising During Tocilizumab<br />

Therapy for Rheumatoid Arthritis —<br />

Philippe Beauchemin, Robert Carruthers<br />

P3.015 Time Course of Multiple<br />

Sclerosis Lesions Visualized with MRI:<br />

Insight into Focal Pathology —Pietro<br />

Maggi, Francesco Zellini, Alessandro Barilaro,<br />

Alessandro Passeri, Luca Massacesi<br />

P3.016 MRI Quantification of Spinal<br />

Cord Atrophy in Multiple Sclerosis: A<br />

Systematic Review and Meta-Analysis —<br />

Courtney Casserly, Stephanie Sankar, Stefan<br />

Baral, Jiwon Oh<br />

P3.017 Autoimmune Tumefactive<br />

Rhombencephalitis Associated with Anti-<br />

TNFα (Adalimumab) Treatment —Kedar<br />

Mahajan, Omar Shah<br />

P3.018 Assessment of High-<br />

Resolution, Clinically Applicable<br />

Quantitative Magnetization Transfer<br />

Imaging in the Cervical Spinal Cord of<br />

Multiple Sclerosis Patients at 3T —Alex<br />

Smith, Richard Dortch, Bailey Lyttle,<br />

Siddharama Pawate, Seth Smith<br />

MS and CNS Inflammatory Disease:<br />

Clinical Trials<br />

P3.019 Absence of HDL Decrease<br />

After Interferon Beta-1a Initiation Is<br />

Associated with Greater Brain Volume<br />

Loss and Lesion Burden in Multiple<br />

Sclerosis Patiens over 4 Years —Tomas<br />

Uher, Dana Horakova, Kelly Fellows, Manuela<br />

Vaneckova, Lukas Sobisek, Zdenek Seidl,<br />

Michaela Tyblova, Jan Krasensky, Eva<br />

Havrdova, Murali Ramanathan<br />

P3.020 Relationship Between VLA-4<br />

Receptor Occupancy and Body Weight<br />

in Natalizumab Treated Patients —John<br />

Foley, Tamara Hoyt, Angelene Christensen,<br />

Ryan Metzger<br />

P3.021 Early Vs Delayed Treatment<br />

with Teriflunomide 14 Mg Results in<br />

Reduced Risk of Disability Progression<br />

in Patients with MS —Paul O'Connor,<br />

Karthinathan Thangavelu, Pascal Rufi,<br />

Philippe Truffinet<br />

P3.022 Patients with Active RRMS and<br />

an Inadequate Response to Prior Therapy<br />

Demonstrate Durable Improvements<br />

in Relapse and Disability Following<br />

Treatment with Alemtuzumab: 5-Year<br />

Follow-Up of the CARE-MS II Study —<br />

Alasdair Coles, Douglas Arnold, Jeffrey<br />

Cohen, Edward Fox, Gavin Giovannoni,<br />

Hans-Peter Hartung, Eva Havrdova, Krzysztof<br />

Selmaj, David Margolin, Karthinathan<br />

Thangavelu, D. Alastair Compston<br />

P3.023 Results from the 48-Week<br />

Blinded Extension of RADIANCE: A<br />

Randomized, Double-Blind, Placebo-<br />

Controlled Phase 2 Trial of Oral Ozanimod<br />

in Relapsing Multiple Sclerosis —Krzysztof<br />

Selmaj, Jeffrey Cohen, Douglas Arnold,<br />

Giancarlo Comi, Amit Bar-Or, Sheila Gujrathi,<br />

Jeffrey Hartung, Allan Olson, Matthew<br />

Cravets, Paul Frohna<br />

68 2016 AAN Annual Meeting Abstract Listing

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