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TECHNICAL MANUAL

For Veterinarians - Merial

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10-day BRD control study with<br />

ZACTRAN ® (gamithromycin)<br />

Field trial design<br />

Sale barn calves (68 bulls and 91 steers) were purchased in Kentucky and Tennessee, and transported<br />

to Study Site 1 in Nebraska. Investigators sourced 308 heifers from livestock markets in Arkansas and<br />

transported them to Study Site 2 in Texas. A total of 467 lightweight calves (286-645 lbs.) were enrolled<br />

in the blinded studies.<br />

On arrival, calves were processed with a viral respiratory vaccine and endectocide, and randomly<br />

assigned to a ZACTRAN group (ZACTRAN SC at 2 mL/110 lbs.) or to a negative control group<br />

(saline SC at 2 mL/110 lbs.).<br />

ZACTRAN controlled BRD for the 10-day study in high-risk cattle. 2<br />

Significantly (P

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