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ISSN NO 2320-5407 Internati<strong>on</strong>al Journal <str<strong>on</strong>g>of</str<strong>on</strong>g> Advanced Research (2013), Volume 1, Issue 5, 71-78<br />

Table 3: Total leucocyte count (TLC) (x 10 3 /cumm) count <str<strong>on</strong>g>of</str<strong>on</strong>g> experimental mice at an interval <str<strong>on</strong>g>of</str<strong>on</strong>g> 15 days (Mean±SE).<br />

Groups/Days 0 15 30 45 60 75 90 105 120 135 150 165 180<br />

C<strong>on</strong>trol 8.91±0.30 9.06±0.17 9.38±0.32 9.91±0.37 10.08±0.51 10.21±0.62 10.53±0.02 10.73±0.12 11.05±0.81 11.32±0.91 11.51±0.07 11.87±0.47 12.11±0.04<br />

CUD (NO 8.65±4.31 8.71±4.36** 8.86±4.51* 8.93±4.70 9.08±5.01* 9.13±5.21 9.18±3.24* 9.20±4.22 9.27±4.56** 9.32±4.61 9.38±4.28 9.46±4.39* 9.53±4.67<br />

DEN)<br />

DEN 9.12±3.20** 9.21±3.52* 9.43±4.07** 9.89±3.81 8.07±3.61 7.42±3.82 6.41±2.01 6.12±3.10* 5.87±2.12* 4.31±3.19 4.16±2.16 4.08±1.87* 3.02±1.45*<br />

CUD 9.02±5.31* 9.13±5.27 9.31±5.17 9.67±4.81** 9.89±4.72 10.07±4.55 9.91±4.31** 9.73±4.24 9.41±4.27* 9.01±3.69 8.23±3.16** 8.11±3.08* 7.81±3.11<br />

A 9.08±5.68* 9.15±5.51* 9.28±5.42 9.57±5.23 9.79±5.05** 9.98±4.93 9.78±4.61* 9.61±4.34 9.32±4.21* 8.91±4.07 8.83±3.21 8.79±3.12 8.64±3.08<br />

B 9.01±6.81* 9.11±6.72 9.19±6.61** 9.41±6.52 9.61±6.37* 9.77±5.83* 9.58±5.61 8.91±5.37 8.87±5.21* 8.81±5.08 8.79±4.61* 8.68±4.52 8.59±3.19**<br />

G 9.10±6.07 9.16±5.91* 9.24±5.82 9.33±5.74** 9.51±5.41* 9.67±5.34* 9.48±5.28 8.87±5.05 8.76±4.81 8.69±4.23* 8.59±4.07 8.41±3.82 8.33±3.61<br />

H 9.07±7.03 9.11±6.87 9.15±6.67** 9.21±6.41 9.38±5.91 9.47±5.80 9.31±5.47* 8.83±5.32** 8.73±5.16 8.62±4.77* 8.57±4.41* 8.46±4.21* 8.30±4.10<br />

A+CUD 8.97±4.02** 9.21±4.47 9.49±3.32 9.89±3.77* 10.08±2.01* 10.33±2.61* 10.69±3.16* 10.93±4.03 11.31±2.12** 11.67±3.41* 11.91±4.91* 12.25±3.53* 12.61±2.17**<br />

B+CUD 8.89±6.31* 9.12±6.27* 9.25±6.08 9.49±5.61* 9.68±5.32* 9.87±5.17* 9.67±5.03 9.47±4.71 9.73±4.57 9.84±4.31 10.08±4.17 10.67±4.08* 10.55±3.18<br />

G+CUD 9.11±5.98 9.18±5.81* 9.27±5.61 9.39±5.47* 9.59±5.27 9.71±5.17 9.51±5.09** 9.30±4.81 9.26±4.67 9.42±4.51 10.02±4.41** 10.17±4.32* 10.21±3.81*<br />

H+CUD 9.03±6.19 9.13±6.01 9.19±5.81** 9.27±5.72 9.44±5.51 9.59±5.42* 9.40±5.31 9.31±5.06* 9.12±4.87* 9.09±4.62* 9.51±4.41 9.88±4.17 10.05±3.14<br />

Significant difference in comparis<strong>on</strong> to c<strong>on</strong>trol(*p≤0.5 and **p≤0.01)<br />

Table 4: Absolute lymphocyte count (ALC) (x 10 6 /cumm) <str<strong>on</strong>g>of</str<strong>on</strong>g> experimental mice at an interval <str<strong>on</strong>g>of</str<strong>on</strong>g> 15 days (Mean±SE).<br />

Groups/Days 0 15 30 45 60 75 90 105 120 135 150 165 180<br />

C<strong>on</strong>trol 4.30±0.69 4.41±0.42 4.59±0.24 4.81±0.49 4.92±0.19 4.98±0.33 5.17±0.54 5.23±0.68 5.41±0.57 5.53±0.28 5.62±0.31 5.81±0.73 5.92±0.98<br />

CUD (NO 4.13±0.70* 4.24±0.72 4.31±0.69* 4.37±0.58* 4.43±0.42 4.45±0.39* 4.48±0.69** 4.49±0.84 4.52±0.92* 4.54±0.14 4.55±0.28* 4.61±0.63* 4.63±0.43<br />

DEN)<br />

DEN 4.41±0.81* 4.43±0.61 4.56±0.71 4.86±0.24* 3.92±0.92** 3.59±0.43* 3.05±0.64 2.94±0.59 2.81±0.36 2.08±0.31* 1.92±0.27* 1.90±0.17 1.36±0.47*<br />

CUD 4.43±0.84* 4.41±0.64 4.54±0.84 4.74±0.18 4.83±0.29 4.85±0.36 4.85±0.47* 4.72±0.53* 4.59±0.61 4.35±0.74* 3.96±0.89 3.89±0.92 3.76±0.53<br />

A 4.42±0.91 4.44±0.738 4.51±0.42** 4.67±0.75 4.78±0.94* 4.86±0.86 4.78±0.73 4.66±0.21** 4.53±0.28* 4.36±0.69 4.28±0.74** 4.25±0.18** 4.19±0.27*<br />

B 4.40±0.94 4.42±0.57 4.44±0.55 4.60±0.85 4.69±0.69 4.77±0.54** 4.65±0.22* 4.33±0.51 4.34±0.49* 4.26±0.16 4.24±0.21* 4.22±0.86 4.18±0.94*<br />

G 4.48±0.73* 4.41±0.82** 4.51±0.98* 4.56±0.37 4.64±0.76 4.76±0.41 4.62±0.47* 4.32±0.53 4.27±0.84 4.23±0.61 4.15±0.65 4.10±0.21* 4.01±0.37*<br />

H 4.44±0.84 4.40±0.34* 4.48±0.76 4.50±0.26** 4.54±0.86* 4.63±0.16 4.56±0.36 4.30±0.61* 4.24±0.42* 4.15±0.69** 4.16±0.48 4.09±0.59* 3.98±0.77<br />

A+CUD 4.39±0.87 4.49±0.29 4.62±0.59 4.84±0.43* 4.90±0.33 5.02±0.77 5.21±0.61 5.33±0.98 4.55±0.71 5.71±0.14 5.83±0.21* 5.98±0.63 6.16±0.42**<br />

B+CUD 4.36±0.89** 4.47±0.19* 4.51±0.41** 4.62±0.82* 4.74±0.27 4.83±0.87* 4.72±0.91** 4.61±0.84** 4.73±0.16** 4.76±0.72 4.91±0.18 5.21±0.68* 5.16±0.80<br />

G+CUD 4.41±0.80* 4.48±0.47 4.53±0.63 4.58±0.92 4.65±0.46** 4.74±0.18* 4.66±0.78 4.56±0.20 4.52±0.91 4.57±0.39* 4.87±0.65* 4.91±0.21 4.90±0.28<br />

H+CUD 4.42±0.79 4.45±0.77 4.48±0.27* 4.52±0.39 4.61±0.65 4.69±0.23 4.59±0.88 4.54±0.49 4.46±0.64* 4.43±0.72* 4.63±0.47 4.86±0.30* 4.89±0.11*<br />

Significant difference in comparis<strong>on</strong> to c<strong>on</strong>trol (*p≤0.5 and **p≤0.01)<br />

Table 5: Absolute Neutrophil count (ANC) (x 10 6 /cumm) <str<strong>on</strong>g>of</str<strong>on</strong>g> experimental mice at an interval <str<strong>on</strong>g>of</str<strong>on</strong>g> 15 days (Mean±SE).<br />

Groups/Days 0 15 30 45 60 75 90 105 120 135 150 165 180<br />

C<strong>on</strong>trol 4.57±0.72 4.50±0.43 4.67±0.29 4.90±0.51 5.00±0.23 5.07±0.38 5.22±0.55 5.32±0.69 5.50±0.59 5.61±0.37 5.71±0.37 5.90±0.77 6.00±0.99<br />

CUD (NO 4.38±0.78** 4.33±0.74** 4.40±0.72 4.44±0.60 4.52±0.45* 4.53±0.43 4.56±0.72 4.57±0.86* 4.60±0.97 4.62±0.19 4.67±0.34 4.70±0.65 4.71±0.47*<br />

DEN)<br />

DEN 4.69±0.83 4.56±0.65** 4.68±0.75 4.92±0.26 4.01±0.96 3.68±0.46 3.14±0.67** 3.00±0.61* 2.90±0.41 2.13±0.34 2.00±0.31 1.99±0.23* 1.49±0.52<br />

CUD 4.51±0.87 4.50±0.69* 4.60±0.89* 4.81±0.21 4.92±0.31 4.99±0.37 4.93±0.49 4.83±0.57 4.67±0.66** 4.47±0.77 4.07±0.92** 3.99±0.95* 3.88±0.56**<br />

A 4.60±0.97* 4.53±0.79 4.61±0.46 4.75±0.77 4.87±0.98 4.96±0.89* 4.86±0.74** 4.78±0.26 4.61±0.32 4.42±0.75* 4.39±0.77 4.36±0.23 4.30±0.31<br />

B 4.58±0.99* 4.51±0.58** 4.56±0.57** 4.68±0.87* 4.78±0.69* 4.85±0.56 4.77±0.26 4.40±0.55 4.40±0.51 4.38±0.19* 4.35±0.26 4.31±0.89 4.26±0.96<br />

G 4.56±0.75 4.54±0.86 4.62±0.99 4.64±0.39* 4.73±0.79* 4.80±0.43** 4.71±0.49 4.41±0.54** 4.35±0.85* 4.31±0.66* 4.26±0.66 4.18±0.24 4.11±0.38<br />

H 4.51±0.87** 4.52±0.37 4.53±0.80* 4.58±0.29 4.66±0.88 4.71±0.17* 4.61±0.38 4.39±0.63 4.32±0.46 4.27±0.74 4.25±0.53* 4.20±0.61 4.09±0.79<br />

A+CUD 4.46±0.89* 4.58±0.31* 4.70±0.61** 4.92±0.45* 4.99±0.35** 5.11±0.78* 5.32±0.64* 5.41±0.99* 5.62±0.74* 5.80±0.15** 5.91±0.23 6.10±0.65** 6.25±0.45*<br />

B+CUD 4.41±0.92 4.51±0.23 4.63±0.46 4.73±0.86 4.80±0.29* 4.91±0.89 4.80±0.93 4.70±0.86 4.81±0.18 4.89±0.74* 5.00±0.20* 5.30±0.69 5.24±0.82<br />

75

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