a-collection-of-research-articles-on-the-medical-potential-of-cow-urine
a-collection-of-research-articles-on-the-medical-potential-of-cow-urine
a-collection-of-research-articles-on-the-medical-potential-of-cow-urine
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Global Journal <str<strong>on</strong>g>of</str<strong>on</strong>g> Pharmacology 4 (1): 41-44, 2010<br />
ISSN 1992-0075<br />
© IDOSI Publicati<strong>on</strong>s, 2010<br />
Antimicrobial Activities <str<strong>on</strong>g>of</str<strong>on</strong>g> Cow Urine Distillate Against Some Clinical Pathogens<br />
1 2 1<br />
Arunkumar Sathasivam, M. Muthuselvam and Rajasekran Rajendran<br />
1<br />
Muthaiyah Research Foundati<strong>on</strong>, Thanjavur, Tamilnadu, India - 613 005<br />
2<br />
Department <str<strong>on</strong>g>of</str<strong>on</strong>g> Microbiology, Marudupandiyar College, Thanjavur, Tamilnadu, India<br />
Abstract: From <strong>the</strong> ancient period <strong>cow</strong>’s <strong>urine</strong> has been used as a medicine. In India, drinking <str<strong>on</strong>g>of</str<strong>on</strong>g> <strong>cow</strong> <strong>urine</strong> has<br />
been practiced for thousands <str<strong>on</strong>g>of</str<strong>on</strong>g> years. Panchagavya is a term used in Ayurveda to describe five important<br />
substances obtained from <strong>cow</strong> namely Urine, Dung, Milk, Ghee and Curd. The present study analyzes <strong>the</strong><br />
antibacterial and antifungal activity <str<strong>on</strong>g>of</str<strong>on</strong>g> Cow Urine Distillate against <strong>the</strong> clinical pathogenic microorganisms.<br />
Antibacterial activity <str<strong>on</strong>g>of</str<strong>on</strong>g> Cow Urine Distillate (5, 10 and 15µl) was analyzed against <strong>the</strong> Bacillus subtilis,<br />
Pseudom<strong>on</strong>as aeruginosa, Klebsiella pneum<strong>on</strong>iae and Salm<strong>on</strong>ella typhi. Maximum antibacterial activity was<br />
observed in Pseudom<strong>on</strong>as aeruginosa (7.06±0.05, 8.08±0.18 and 10.4±1.23, mm in diameter, respectively) and<br />
Salm<strong>on</strong>ella typhi (6.3±1.23, 8.06±0.17 and 10.4±1.2, mm in diameter, respectively). Antifungal activity <str<strong>on</strong>g>of</str<strong>on</strong>g> <strong>cow</strong><br />
<strong>urine</strong> distillate was analysed against Aspergillus niger and Aspergillus flavus. When <strong>the</strong> two fungal organisms<br />
were compared, maximum growth suppressi<strong>on</strong> was observed in Aspergillus niger (3±0.14, 6.3±1.2 and 7.06±0.04,<br />
mm in diameter) than Aspergillus flavus (2.03±0.25, 4.9±0.26 and 6.3±1.2, mm in diameter, respectively).<br />
Finally c<strong>on</strong>cluded that <strong>the</strong> <strong>cow</strong> <strong>urine</strong> distillate has antibacterial and antifungal activities and <strong>the</strong> inhibitory<br />
activity can be used in <strong>the</strong> c<strong>on</strong>trol <str<strong>on</strong>g>of</str<strong>on</strong>g> bacteria and fungi <str<strong>on</strong>g>of</str<strong>on</strong>g> various origins.<br />
Key words: Cow Urine Distillate<br />
Antibacterial and Antifungal Activity<br />
INTRODUCTION<br />
treatment <str<strong>on</strong>g>of</str<strong>on</strong>g> falling body parts, discharging lymphs and<br />
organism infested organs, use <str<strong>on</strong>g>of</str<strong>on</strong>g> <strong>cow</strong>’s <strong>urine</strong> (al<strong>on</strong>g with<br />
In Veda, <strong>cow</strong>’s <strong>urine</strong> was compared to <strong>the</strong> nectar. In some o<strong>the</strong>r ingredients) has been recommended for bath,<br />
substrata, several medicinal properties <str<strong>on</strong>g>of</str<strong>on</strong>g> <strong>cow</strong>’s <strong>urine</strong> anointing and intake [2]. The <strong>cow</strong> <strong>urine</strong> distillate has been<br />
have been menti<strong>on</strong>ed and are known to cause weight loss, patented as activity enhancer and availability facilitator<br />
reversal <str<strong>on</strong>g>of</str<strong>on</strong>g> certain cardiac and kidney problems, for bioactive molecules including anti- infective and<br />
indigesti<strong>on</strong>, stomach ache, edema, etc. Cow <strong>urine</strong> has a anti-cancer agents (US Patent No 6410 059/2002) [3].<br />
unique place in Ayurveda and has been described in Chakra pani mishra in vishva vallabba recommends using<br />
‘Sushrita Sumhita’ and Ashtanga Sangraha’ to be <strong>the</strong> extracts <str<strong>on</strong>g>of</str<strong>on</strong>g> <strong>cow</strong> <strong>urine</strong> in herbal insecticides [4]. Feeding <str<strong>on</strong>g>of</str<strong>on</strong>g><br />
most effective substance secreti<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> animal origin with <strong>cow</strong> <strong>urine</strong> increased <strong>the</strong> feed intake in white legborn<br />
innumerable <strong>the</strong>rapeutic values. It has been recognized as layers [5]. The present study was carried out to prepare<br />
water <str<strong>on</strong>g>of</str<strong>on</strong>g> life or “Amrita” (Beverages <str<strong>on</strong>g>of</str<strong>on</strong>g> immortality), <strong>the</strong> <strong>cow</strong> <strong>urine</strong> distillate and to determine <strong>the</strong> antibacterial and<br />
nectar <str<strong>on</strong>g>of</str<strong>on</strong>g> <strong>the</strong> God. In India, drinking <str<strong>on</strong>g>of</str<strong>on</strong>g> <strong>cow</strong> <strong>urine</strong> has been antifungal activities.<br />
practiced for thousands <str<strong>on</strong>g>of</str<strong>on</strong>g> years. Panchagavya is a term<br />
used in Ayurveda to describe five important substances<br />
MATERIALS AND METHODS<br />
obtained from <strong>cow</strong> namely Urine, Dung, Milk, Ghee and<br />
Curd. A number <str<strong>on</strong>g>of</str<strong>on</strong>g> formulati<strong>on</strong>s menti<strong>on</strong>ed in Ayurveda Collecti<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> Sample: Cow <strong>urine</strong> sample was collected<br />
describe <strong>the</strong> use <str<strong>on</strong>g>of</str<strong>on</strong>g> Panchagavya comp<strong>on</strong>ents ei<strong>the</strong>r al<strong>on</strong>e from <strong>cow</strong> farm (at Avanam, Thanjavur Dt) using sterile<br />
or in combinati<strong>on</strong> with drugs <str<strong>on</strong>g>of</str<strong>on</strong>g> herbal, animal or mineral c<strong>on</strong>tainer and stored for fur<strong>the</strong>r uses.<br />
origin [1].<br />
An exhaustive reference <str<strong>on</strong>g>of</str<strong>on</strong>g> <strong>cow</strong>’s <strong>urine</strong> having CUD Preparati<strong>on</strong>: Cow <strong>urine</strong> was distilled at 100°C using<br />
curative properties in skin diseases, especially leprosy, distillati<strong>on</strong> apparatus [6]. The single distilled <strong>cow</strong> <strong>urine</strong><br />
is referred to in Caraka samhita. Fur<strong>the</strong>rmore, in <strong>the</strong> was acidified by lowering <strong>the</strong> pH below 2.0 with <strong>the</strong><br />
Corresp<strong>on</strong>ding Author: Arunkumar Sathasivam, Muthaiyah Research Foundati<strong>on</strong>, Thanjavur, Tamilnadu, India-613 005.<br />
Mob: 09486131235, Email: microbiologyarun@yahoo.com<br />
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