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The World in 2030

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<strong>The</strong> <strong>World</strong> <strong>in</strong> <strong>2030</strong> 299<br />

drugs by target<strong>in</strong>g them more selectively to tumors<br />

and boost<strong>in</strong>g their solubility <strong>in</strong> water.<br />

Besides be<strong>in</strong>g safer and easier to adm<strong>in</strong>ister, polymeric<br />

micelles ma<strong>in</strong>ta<strong>in</strong> anti-cancer drugs like rapamyc<strong>in</strong><br />

<strong>in</strong> blood plasma for longer periods than do standard<br />

formulations, Kwon has found. It’s a promis<strong>in</strong>g<br />

result that could give the drugs a greater chance of<br />

accumulat<strong>in</strong>g at tumor sites.<br />

Polymeric micelles may also make it easier to mix<br />

stronger cancer-fight<strong>in</strong>g cocktails conta<strong>in</strong><strong>in</strong>g more<br />

than one chemotherapeutic agent. Do<strong>in</strong>g so now is<br />

a challenge because hydrophobic drugs <strong>in</strong> solution<br />

together tend to ‘crash out,’ says Kwon, becom<strong>in</strong>g<br />

particulate, aggregated — and useless. 525<br />

And plastics are be<strong>in</strong>g used alongside carbon nanotubes to<br />

help fight HIV, as the New Scientist reported <strong>in</strong> March 2007:<br />

Carbon nanotubes have been used to smuggle HIVblock<strong>in</strong>g<br />

molecules <strong>in</strong>to human cells. Although prelim<strong>in</strong>ary,<br />

the discovery could lead to new treatments<br />

for the deadly virus. A complex chemical trick was<br />

used to attach the siRNA to the carbon nanotubes.<br />

Carbon-hydrogen cha<strong>in</strong>s, which b<strong>in</strong>d tightly to nanotubes,<br />

were connected with a polymer called polyethylene<br />

glycol (PEG). This was then fixed to siRNA<br />

via two sulphur atoms. 526<br />

In addition plastic robots are already help<strong>in</strong>g surgeons to<br />

operate <strong>in</strong> conditions unsuitable for conventional surgery.

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