AIR POLLUTION – MONITORING MODELLING AND HEALTH

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346 Air Pollution – Monitoring, Modelling and Health C D Fig. 1. Meta-analyses of ambient NO 2 effects on lung function in children. (A) FVC (B) FEV 1 (C) MMEF (D) PEFR.
Air Pollution and Health Effects in Children 347 4. Gender difference for the air pollution effects in children Despite the literature is far from consistent, there is growing epidemiological evidence of the differing associations between air pollution and respiratory health for males and females (Clougherty 2010; Keitt et al. 2004). Generally, many investigations were focused on the differences of gender or sex, however, there is also the distinction between definition of gender and sex (Clougherty 2010). As a social construct, Krieger et al. (2003) had expatiated that gender includes cultural norms, roles, and behaviors shaped by relations among women and men and among girls and boys; however, sex, a biological construct, is based on physiologic differences enabling reproduction, defined by physiologic characteristics (especially reproductive organs) or chromosomal complement. Also, Clougherty et al. (2010) have given recently a summary account that gender, inherently social, varies continuously over multiple dimensions over the life course, whereas sex is normally dichotomous. Gender is shaped at the societal level and varies across nation, culture, class, race, ethnicity, nationality, sexuality, and religion. Gender describes patterns of behavior, place, and role, determining where people spend time and their activities, thereby shaping exposure distributions. Sex-linked traits (e.g., hormonal status, body size) influence biological transport of environmentally derived chemicals (Clougherty 2010). The gender analyses are more common in occupational epidemiology than in environmental health, because persistent job stratification by gender has produced marked differences in occupational exposures to chemical agents, ergonomic demands, injury, and psychosocial stressors (Clougherty 2010). Compared with the studies among adults, disentangling gender effects in air pollution–health associations among children may be more complicated, because lung function growth rates (critical periods for pollution effects) differ by sex (Berhane et al. 2000). Most air pollution epidemiology studies among children examine chronic exposures, although outcomes considered vary widely, including lung function growth, wheeze, asthma onset and exacerbation, and symptoms. It has been reported elsewhere that boys were more susceptible than girls to the effects of environmental factors including the effects of ambient air pollution. A 10-yr prospective cohort study of Southern California children in grade 4, 7 and 10 indicated that, based on the 1986–1990 exposure data, prevalence of wheeze was associated with exposure to NO 2 (OR=1.48; 95% CI: 1.08–2.02) and acid (OR=1.55; 95% CI: 1.09–2.21) in males only; also, based on the 1994 exposure measurements, again see a positive association of NO 2 (OR=1.54; 95% CI: 1.08–2.19) and acid (OR=1.45; 95% CI: 1.14–1.83) with wheeze in boys only (Peters et al. 1999a). The results from an international collaborative study on the impact of Traffic-Related Air Pollution on Childhood Asthma (TRAPCA) showed, when stratified analysis by gender, significant associations between residential PM 2.5 , NO 2 and respiratory symptoms (e.g., cough without infection, cough at night) only among boys but not among girls 0–2 years of age (Gehring et al. 2002). In a prospective cohort study of annual mean total suspended particle (TSP) and SO 2 exposures among preadolescent children in Krakow, Poland, Jedrychowski et al. (1999) reported stronger associations with FVC and FEV 1 among boys than among girls. The authors noted sex-differing lung growth rates, producing different critical periods for pollution effects. Also, the cohort study from Southern California suggested that the relation between FEV 1 growth and traffic air pollution was noticeably larger in boys than in girls, although a test of effect modification by sex was nonsignificant (p=0.10) (Gauderman et al. 2007). Some authors have ever explained that the
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AIR POLLUTION - MONITORING, MODELLI
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Contents Preface IX Chapter 1 Urban
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Preface This book provides a compre
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AIR POLLUTION – MONITORING MODELLING AND HEALTH

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