LEGIONELLA - World Health Organization
LEGIONELLA - World Health Organization LEGIONELLA - World Health Organization
in warmer regions appears to be lacking, but up to 10 8 cells/litre have been found in surface waters in tropical regions, and Legionella has been cultured in high numbers from warm water sources (Ortiz-Roque & Hazen, 1987). Naturally occurring L. pneumophila can survive and multiply in water at temperatures of 25–45 °C, with an optimal range of 32–42 °C and the greatest increase in viable counts at 37–42 °C (Yee & Wadowsky, 1982). The multiplication rate decreases at temperatures below 37 °C, with no observable growth below 20 °C (HSE, 2004). In certain geographical regions, temperatures may routinely be above 20 ºC and, in some cases, may reach optimal temperatures for legionellae growth. 4.4 Monitoring This section should be read in conjunction with Section 3.3.2 of Chapter 3. The steps involved in monitoring, some of which are discussed below, are to: • identify control measures (Section 4.4.1) • monitor control measures (Section 4.4.2) • validate effectiveness of the WSP. 4.4.1 Identify control measures This section should be read in conjunction with Table 3.2 of Chapter 3, which provides information on the advantages and disadvantages of alternative methods of controlling Legionella in piped water systems. The focus of attention in managing legionellae risks should be on preventing both proliferation and exposure, in line with the multiple-barrier approach that forms part of a WSP. Systems will need to be assessed individually, and any treatment will need to be validated by testing for its effectiveness against legionellae and for the presence of legionellae in operating systems. For example, in order to choose appropriate control measures, it will be necessary to know the “normal” operating temperature of the water supply. Water quality and treatment — control measures Water from the supplier should meet the appropriate drinking-water standards or guidelines of the jurisdiction (e.g. WHO, 2004), and should not contain high levels of nutrients. Measures for reducing numbers of Legionella are not routinely applied in drinking-water distribution systems because (as explained in Section 4.3) levels of Legionella are usually below the detection limit of culture techniques. However, in most countries, surface water treatment includes a series of barriers to eliminate or inactivate pathogenic microorganisms of faecal origin. These physical techniques, such as coagulation–sedimentation, filtration and disinfection will also reduce the number of legionellae (Kuchta et al., 1983). LEGIONELLA AND THE PREVENTION OF LEGIONELLOSIS
Where temperature controls (discussed below) cannot be maintained, an alternative means of control needs to be implemented; for example, where legionellae multiply in warm areas of cold-water systems. The effectiveness of control measures for Legionella depends on many variables. Physical systems such as ultraviolet (UV) and filtration may be satisfactory if fitted near the point of use, but they are not dispersive; that is, they do not form a residual level of treatment throughout the water system and therefore will not affect biofilms harbouring Legionella downstream of their point of use. Criteria for a universal acceptable level of effectiveness have not been defined, but might include a required log reduction of Legionella in water and an effect on biofilms (e.g. reduction of formation or growth of biofilms). Applying alternative control techniques requires detailed consideration of the extent and complexity of the system, and of the composition of the water. Where alternative measures are implemented, monitoring is needed to ensure that controls are adequate and maintained (see Section 4.5). Tap diffusers reduce water use but can increase aerosol production. Therefore, in high-risk areas, such as hospitals, diffusers should not be installed (and facilities should consider removing diffusers that are already in place). Mixing valves should be as close to the shower outlet as possible, and shower fittings should be detachable so that they can be routinely cleaned and disinfected. Distribution systems — control measures Control of legionellae should begin at the design stage of the water system. There are many different designs for modern plumbed water systems that supply hot and cold water in buildings. Systems may be gravity fed, with a storage tank for cold water fed by the mains supply, or they may be pressurized, with no intermediate storage tank. Hot water is supplied from a water heater, calorifier, boiler or plate heat exchanger, depending on the scale of the system. Cold water is distributed either directly from the mains supply or via a cold-water storage tank. Pipes should be as short as possible. In complex systems, regulating valves should be used to control flow. Deadends should be avoided in both the design and construction phases, and in existing systems they should either be removed or regularly flushed. Standard system fittings should include devices to prevent backflow on heat production systems, and purge valves to prevent scaling and corrosion and facilitate monitoring. These should be installed at appropriate locations in the system, according to national standards. Construction materials — control measures The materials used to construct piped water distribution systems should be compatible with the chemical quality of water (after a corrective treatment) and should minimize bacterial growth. LEGIONELLA AND THE PREVENTION OF LEGIONELLOSIS
- Page 37 and 38: Table . R sk factors for Legionella
- Page 39 and 40: In the outbreak of Legionnaires’
- Page 41 and 42: Table . Potent al treatments for d
- Page 43 and 44: 1.4.2 Species and serogroups associ
- Page 45 and 46: Other causes of infection In Europe
- Page 47 and 48: The interaction of virulent legione
- Page 49 and 50: 1.5.2 Surface structures involved i
- Page 51 and 52: 1.5.4 Host defence The host defence
- Page 53 and 54: Chapter 2 Ecology and environmental
- Page 55 and 56: L. pneumophila is thermotolerant an
- Page 57 and 58: 2.2.3 Environmental factors and vir
- Page 59 and 60: Figure 2.1 Biofilm formation Biofil
- Page 61 and 62: 2.4 Sources of Legionella infection
- Page 63 and 64: Chapter 3 Approaches to risk manage
- Page 65 and 66: Table . Cool ng tower outbreaks Fac
- Page 67 and 68: Even when a source reaches a state
- Page 69 and 70: The WSP should be prepared in conju
- Page 71 and 72: Identify control measures Control m
- Page 73 and 74: F gure . Dec mal reduct on t mes fo
- Page 75 and 76: Method Advantages D sadvantages Dos
- Page 77 and 78: Validate effectiveness of water saf
- Page 79 and 80: • clear statements of responsibil
- Page 81 and 82: Chapter 4 Potable water and in-buil
- Page 83 and 84: The remainder of this chapter provi
- Page 85 and 86: 4.3.1 Document and describe the sys
- Page 87: Construction materials — risk fac
- Page 91 and 92: 4.4.2 Monitor control measures This
- Page 93 and 94: Chapter 5 Cooling towers and evapor
- Page 95 and 96: 5.1.1 Cross-flow cooling towers As
- Page 97 and 98: water treatments (including chemica
- Page 99 and 100: 5.3 System assessment This section
- Page 101 and 102: Spray drift — risk factors Even w
- Page 103 and 104: The section on control measures for
- Page 105 and 106: • periodic or continuous bleed-of
- Page 107 and 108: Box . Po nts to be noted when clean
- Page 109 and 110: In certain circumstances, samples m
- Page 111 and 112: Table . Example documentat on for m
- Page 113 and 114: Chapter 6 Health-care facilities Ma
- Page 115 and 116: For 1999 and 2000, a total of 384 c
- Page 117 and 118: 6.3 System assessment This section
- Page 119 and 120: Table . Type of colon zat on of wat
- Page 121 and 122: 6.4.1 Identify control measures Thi
- Page 123 and 124: 6.5.1 Prepare management procedures
- Page 125 and 126: Until the situation is under contro
- Page 127 and 128: Chapter 7 Hotels and ships Roisin R
- Page 129 and 130: F gure . Detected and reported case
- Page 131 and 132: Table . Rev ew of outbreaks (more t
- Page 133 and 134: 7.2 Water safety plan overview WSPs
- Page 135 and 136: The risk of legionellosis is increa
- Page 137 and 138: Kingdom to 66% in Spain (Starlinger
Where temperature controls (discussed below) cannot be maintained, an alternative means<br />
of control needs to be implemented; for example, where legionellae multiply in warm areas<br />
of cold-water systems. The effectiveness of control measures for Legionella depends on many<br />
variables. Physical systems such as ultraviolet (UV) and filtration may be satisfactory if fitted<br />
near the point of use, but they are not dispersive; that is, they do not form a residual level of<br />
treatment throughout the water system and therefore will not affect biofilms harbouring<br />
Legionella downstream of their point of use. Criteria for a universal acceptable level of effectiveness<br />
have not been defined, but might include a required log reduction of Legionella in water and<br />
an effect on biofilms (e.g. reduction of formation or growth of biofilms).<br />
Applying alternative control techniques requires detailed consideration of the extent and complexity<br />
of the system, and of the composition of the water. Where alternative measures are implemented,<br />
monitoring is needed to ensure that controls are adequate and maintained (see Section 4.5).<br />
Tap diffusers reduce water use but can increase aerosol production. Therefore, in high-risk<br />
areas, such as hospitals, diffusers should not be installed (and facilities should consider removing<br />
diffusers that are already in place). Mixing valves should be as close to the shower outlet as<br />
possible, and shower fittings should be detachable so that they can be routinely cleaned and<br />
disinfected.<br />
Distribution systems — control measures<br />
Control of legionellae should begin at the design stage of the water system. There are many<br />
different designs for modern plumbed water systems that supply hot and cold water in buildings.<br />
Systems may be gravity fed, with a storage tank for cold water fed by the mains supply, or<br />
they may be pressurized, with no intermediate storage tank. Hot water is supplied from a water<br />
heater, calorifier, boiler or plate heat exchanger, depending on the scale of the system. Cold<br />
water is distributed either directly from the mains supply or via a cold-water storage tank.<br />
Pipes should be as short as possible. In complex systems, regulating valves should be used to<br />
control flow. Deadends should be avoided in both the design and construction phases, and in<br />
existing systems they should either be removed or regularly flushed.<br />
Standard system fittings should include devices to prevent backflow on heat production systems,<br />
and purge valves to prevent scaling and corrosion and facilitate monitoring. These should be<br />
installed at appropriate locations in the system, according to national standards.<br />
Construction materials — control measures<br />
The materials used to construct piped water distribution systems should be compatible with the<br />
chemical quality of water (after a corrective treatment) and should minimize bacterial growth.<br />
<strong>LEGIONELLA</strong> AND THE PREVENTION OF LEGIONELLOSIS