INTERPOL HANDBOOK ON DNA DATA EXCHANGE AND PRACTICE

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NameTH01, TPOX,CSF1POmonoplexes(silver stain)AmpF/STR BlueAmpF/STR GreenISourceReleaseDateSTR Loci includedPromega Feb 1993 TH01 TPOX CSF1POAppliedBiosystemsAppliedBiosystemsOct 1996 D3S1358 VWA FGAJan 1997 Amelogenin TH01 TPOX CSF1POCTTv Promega Jan 1997 CSF1PO TPOX TH01 VWAFFFL Promega Jan 1997 F13A1 FES/ESP F13B LPLGammaSTR Promega Jan 1997 D16S593 D13S317 D7S820 D5S818PowerPlex(version 1.1 and1.2 later)AmpF/STRProfilerAmpF/STRProfiler PlusAmpF/STRCofilerAmpF/STR SGMPlusPowerPlex 2.1(for HitachiFMBIO users)PromegaAppliedBiosystemsAppliedBiosystemsAppliedBiosystemsAppliedBiosystemsJan 1997 CSF1PO TPOX TH01 VWA D16S593Sep 1997 D13S317 D7S820 D5S818May 1997Dec 1997May 1998Feb 1999Promega Jun 1999PowerPlex 16 Promega May 2000PowerPlex 16 BIO(for HitachiFMBIO users)Table 6: Commercially available STR kits – chronological overviewPromega May 2001D3S1358 VWA FGA Amelogenin TH01TPOX CSF1PO D5S818 D13S317 D7S820D3S1358 VWA FGA Amelogenin D8S1179D21S11 D18S51 D5S818 D13S317 D7S820D3S1358 D16S539 Amelogenin TH01 TPOXCSF1PO D7S820D3S1358 VWA D16S539 D2S1338 AmelogeninD8S1179 D21S11 D18S51 D19S433 THo1FGAD3S1358 THo1 D21S11 D18S51 VWAD8S1179 TPOX FGA Penta ECSF1PO FGA TPOX TH01 VWAD3S1358 D5S818 D7S820 D8S1179 D13S317D16S539 D18S51 D21S11 Penta D Penta EAmelogeninCSF1PO FGA TPOX TH01 VWAD3S1358 D5S818 D7S820 D8S1179 D13S317D16S539 D18S51 D21S11 Penta D Penta EAmelogeninPAGE 92 APPENDIX 3what is forensic dna profiling?
NameAmpF/STRIdentifilerAmpF/STRProfiler Plus IDSourceReleaseDateAppliedBiosystems Jul 2001AppliedBiosystemsSep 2001PowerPlex ES Promega Mar 2002AmpF/STR SefilerAppliedBiosystemsSep 2002STR Loci includedCSF1PO FGA TPOX TH01 VWAD3S1358 D5S818 D7S820 D8S1179 D13S317D16S539 D18S51 D21S11 D2S1338 D19S433AmelogeninD3S1358 VWA FGA Amelogenin D8S1179D21S11 D18S51 D5S818 D13S317 D7S820FGA TH01 VWA D3S1358 D8S1179D18S51 D21S11 SE33 AmelogeninFGA TH01 VWA D3S1358 D8S1179D16S539 D18S51 D21S11 D2S1338 D19S433SE33 AmelogeninTable 7: example of a <strong>DNA</strong> profile in compliance with international standardsVWA THO1 D21S11 FGA D8S1179 D3S1358 D18S51 Amelogenin17 18 6 8 29 31.2 22 26 14 15 17 17 14 15 X YTPOX CSF1P0 D13S317 D7S820 D5S818 D16S539 D2S1338 D19S43311 13 8 11 11 12Penta D Penta E FES F13A1 F13B SE33 CD4 GABA28 28.2 10 10APPENDIX 3what is forensic dna profiling?PAGE 93
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INTERPOLINTERPOL HANDBOOK ONDNA DAT
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INTERPOLINTERPOL HANDBOOK ONDNA DAT
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dna investigative considerations .
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INTRODUCTIONby ronald k. noblethe s
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•back to basics: the use of dna i
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•the dna databaseThe INTERPOL DNA
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PART i: CASE SCENARIOFICTITIOUS SCE
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He cautiously pushes the door open
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The only obvious item of evidential
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• Consider physical evidence that
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DNA SAMPLINGAND EVIDENCE COLLECTION
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•crime scene investigator (csi)Wh
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•potential sources of dnaThere ar
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Open the sampling kit and ensure th
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If at any time during the sampling
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IN THE LABORATORYOnce evidence has
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INTERPRETATION OF THE DNA PROFILEAs
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THE MATCH REPORTTo get to step 5 of
Page 43: QUALITY ASSURANCEQuality principles
Page 47 and 48: to ensure the best possible results
Page 49 and 50: •in-laboratory trainingAnother as
Page 51 and 52: •key education requirementAnother
Page 53 and 54: PART II: an overviewdna databasesPA
Page 55 and 56: With the increasing use of DNA prof
Page 57 and 58: INTERPOLMember CountryCrimeSceneRef
Page 59 and 60: THE VALUE OF A NATIONAL DNA DATABAS
Page 61 and 62: ESTABLISHING AN EFFECTIVE DNADATABA
Page 63 and 64: •need for a dna databaseOnce the
Page 65 and 66: PublicityOnce a database has been e
Page 67 and 68: It is not only the individual who i
Page 69 and 70: LEGISLATIONSpecific legislation is
Page 71: In conclusion, legislation has to f
Page 74 and 75: THE USE OF POST-CONVICTION DNA TEST
Page 76 and 77: FAMILIAL SEARCHINGThe idea that a D
Page 78 and 79: “Familial searching” has its ad
Page 80 and 81: Recent progress in the forensic use
Page 82 and 83: The most informative target loci fo
Page 84 and 85: Another obvious issue associated wi
Page 86 and 87: APPENDIX 1INTERPOL Standard Set of
Page 88 and 89: 1 16 DNA CODE:VWA THO1 D21S11 FGA D
Page 90 and 91: the process of dna analysisThe biol
Page 92 and 93: AnalysisThe data generated by elect
Page 96 and 97: APPENDIX 4questions around anintell
Page 98 and 99: APPENDIX 5DNA FACT SHEETDNA Profili
Page 100 and 101: APPENDIX 6interpol dna search reque
Page 102 and 103: APPENDIX 7recommendationsfrom the e
Page 104 and 105: 21. As a national DNA-database regu
Page 106 and 107: Glossary1-24/7AlleleAmelogeninBiolo
Page 108 and 109: Member CountriesMitochondrial DNA(m
Page 110 and 111: ABBREVIATIONSaimsascld/labasipbelte
Page 112 and 113: eferences1 Retrieved from: www.iso.
Page 114 and 115: 40 Sibille, I., Duverneuil, C., Lor
Page 117 and 118: OIPC-INTERPOL200, Quai Chales de Ga
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INTERPOL HANDBOOK ON DNA DATA EXCHANGE AND PRACTICE

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