Oil for Life to Balance omega-3 polyunsaturated fatty acids ... - Oil4Life

10 kg/day of EPA+DHA 2:1 as in Oil4Life Balance. The supplementation of EPA and
DHA in relatively high doses compared to body weight, verified that an improved AA/EPA
balance in the cell membrane increased attention level and decrease both hyperactivity levels
and impulsiveness. There was a correlation between the dose of long chain omega-3 fatty
acids, the decrease of AA/EPA ratio and/or the entity of the clinical improvement. Our data
are in agreement with the results obtained by different Authors.
Depletion of omega-3 fatty acid levels in red blood cell membranes of depressed patients has
been reported. A significant positive relationship was observed between the severity of the
illness and the AA/EPA ratio in serum phospholipids and in erythrocyte membranes.
Preliminary results in our laboratory on depressed elderly patients demonstrated that
counteracting and balancing high levels of AA with EPA+DHA 2:1, as in Oil4Life Balance,
also decreased depression symptoms. Several authors have also reported lower
concentrations of erythrocyte essential fatty acids among schizophrenic patients as compared
with control. DHA is the major acid of neurological and retinal membranes. It makes up
more than 30% of the structural lipids of the neuron. Low levels of circulating DHA may be
a significant risk in the development of Alzheimer dementia. The inability to maintain a high
level of DHA may be due to a reduced capacity to synthesise DHA late in life, as the result
of a reduction in Δ-6-desaturase activity. Alterations in phospholipids, which are structural
components of all cell membranes in the brain, may induce changes in membrane fluidity
and, consequently, in various neurotransmitter systems that are believed to be related to the
pathophysiology of major depression.
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