safety data sheet - Oxoid
safety data sheet - Oxoid
safety data sheet - Oxoid
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Creation Date<br />
1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE<br />
COMPANY/UNDERTAKING<br />
Product Identifier<br />
Product Description: Shigella boydii Polyvalent 1 Agglutinating Antisera<br />
Cat No. R30163901<br />
Relevant identified uses of the substance or mixture and uses advised against<br />
Recommended Use Laboratory chemicals<br />
Uses advised against No Information available<br />
Emergency Telephone Number<br />
Carechem 24: +44 (0) 1865 407333<br />
Classification of the substance or mixture<br />
REGULATION (EC) No 1272/2008<br />
Not hazardous<br />
2. HAZARDS IDENTIFICATION<br />
Classification according to EU Directives 67/548/EEC or 1999/45/EC<br />
For the full text of the R-phrases and H-Statements mentioned in this Section, see Section 16<br />
R-phrase(s) none<br />
Label Elements<br />
Signal Word None<br />
Hazard Statements<br />
22-Nov-2011<br />
Details of the supplier of the <strong>safety</strong> <strong>data</strong> <strong>sheet</strong><br />
Company<br />
Supplier<br />
REMEL (EUROPE) LIMITED<br />
<strong>Oxoid</strong> Ltd.<br />
Remel House<br />
Wade Road<br />
Clipper Boulevard West<br />
Basingstoke, Hants, UK<br />
Crossways, Dartford<br />
RG24 8PW<br />
Kent. DA2 6PT<br />
Telephone: +44 (0) 1256 841144<br />
UK<br />
Tel: (+44) 1322 295600<br />
Fax: (+44) 1322 225413<br />
mbd-sds@thermofisher.com<br />
E-mail address mbd-sds@thermofisher.com<br />
SAFETY DATA SHEET<br />
Revision Date 22-Nov-2011 Revision Number 1<br />
_____________________________________________________________________________________________<br />
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Shigella boydii Polyvalent 1 Agglutinating Antisera<br />
Revision Date 22-Nov-2011<br />
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Other Hazards<br />
No information available.<br />
3. COMPOSITION/INFORMATION ON INGREDIENTS<br />
Component EC-No. Weight % CAS-No Classification GHS<br />
Classification<br />
REACH No.<br />
Phenol<br />
EEC No. 203-
Shigella boydii Polyvalent 1 Agglutinating Antisera<br />
Revision Date 22-Nov-2011<br />
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Extinguishing media which must not be used for <strong>safety</strong> reasons<br />
No information available.<br />
Special hazards arising from the substance or mixture<br />
Thermal decomposition can lead to release of irritating gases and vapors<br />
Advice for fire-fighters<br />
As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective<br />
gear<br />
6. ACCIDENTAL RELEASE MEASURES<br />
Personal precautions, protective equipment and emergency procedures<br />
Avoid contact with skin, eyes and clothing. Ensure adequate ventilation.<br />
Environmental precautions<br />
Prevent further leakage or spillage if safe to do so<br />
Methods and material for containment and cleaning up<br />
Soak up with inert absorbent material. Clean contaminated surface thoroughly.<br />
Precautions for Safe Handling<br />
7. HANDLING AND STORAGE<br />
Avoid contact with skin, eyes and clothing. Do not breathe vapors or spray mist. Ensure adequate ventilation.<br />
Conditions for safe storage, including any incompatibilities<br />
Keep container tightly closed. Keep at temperatures between 2° and 8 °C.<br />
Specific End Uses<br />
Control parameters<br />
8. EXPOSURE CONTROLS/PERSONAL PROTECTION<br />
SAFETY DATA SHEET<br />
Exposure limits<br />
Component European Union The United Kingdom France Belgium Spain<br />
_____________________________________________________________________________________________<br />
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Revision Date 22-Nov-2011<br />
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Phenol<br />
Possibility of significant<br />
uptake through the skin<br />
STEL: 6 ppm 15 min<br />
STEL: 23.4 mg/m 3 15<br />
min<br />
TWA: 2 ppm 8 hr<br />
TWA: 7.8 mg/m 3 8 hr<br />
Skin<br />
VME: 2 ppm 8 heures.<br />
restrictive limit<br />
VME: 7.8 mg/m 3 8<br />
heures. restrictive limit<br />
VLCT: 4 ppm<br />
VLCT: 15.6 mg/m 3<br />
Skin<br />
Sodium hydroxide 2 mg/m 3 STEL VME: 2 mg/m 3 8<br />
heures.<br />
TWA: 2 ppm 8 uren<br />
TWA: 7.8 mg/m 3 8 uren<br />
Skin<br />
Skin<br />
VLA-ED: 2 ppm 8 horas<br />
VLA-ED: 8 mg/m 3 8<br />
horas<br />
2 mg/m 3 VLE VLA-EC: 2 mg/m 3 15<br />
minutos<br />
Component Italy Germany Portugal The Netherlands Finland<br />
Phenol<br />
Sodium hydroxide<br />
TWA: 2 ppm 8 ore.<br />
TWA: 7.8 mg/m3 skin notation<br />
8 ore. Skin<br />
Skin TWA: 2 ppm 8 Stunden.<br />
exposure factor 2<br />
TWA: 8 mg/m3 8<br />
Stunden. exposure<br />
factor 2<br />
2 mg/m 3 TWA<br />
(inhalable fraction)<br />
TWA: 5 ppm 8 horas<br />
Skin<br />
Skin<br />
TWA: 8 mg/m 3 8 uren<br />
TWA: 2 ppm 8 tunteina<br />
TWA: 8 mg/m 3 8<br />
tunteina<br />
STEL: 5 ppm 15<br />
minuutteina<br />
STEL: 20 mg/m 3 15<br />
minuutteina<br />
Skin<br />
Ceiling: 2 mg/m 3 STEL: 2 mg/m 3 15<br />
minuutteina<br />
Ceiling: 2 mg/m 3<br />
Component Austria Denmark Switzerland Poland Norway<br />
Phenol<br />
Sodium hydroxide<br />
Skin<br />
MAK: 2 ppm 8 Stunden<br />
MAK: 7.8 mg/m 3 8<br />
Stunden<br />
STEL: 4 mg/m 3 15<br />
Minuten<br />
MAK: 2 mg/m 3 8<br />
Stunden<br />
TWA: 1 ppm 8 timer<br />
TWA: 4 mg/m 3 8 timer<br />
Skin<br />
Skin<br />
STEL: 5 ppm 15<br />
Minuten<br />
STEL: 19 mg/m 3 15<br />
Minuten<br />
MAK: 5 ppm 8 Stunden<br />
MAK: 19 mg/m 3 8<br />
Stunden<br />
Ceiling: 2 mg/m 3 STEL: 2 mg/m 3 15<br />
Minuten<br />
MAK: 2 mg/m 3 8<br />
Stunden<br />
NDS: 7.8 mg/m 3 8<br />
godzinach<br />
NDSCh: 1 mg/m 3 15<br />
minutach<br />
NDS: 0.5 mg/m 3 8<br />
godzinach<br />
TWA: 1 ppm 8 timer<br />
TWA: 4 mg/m 3 8 timer<br />
STEL: 3 ppm 15<br />
minutter.<br />
STEL: 8 mg/m 3 15<br />
minutter.<br />
Skin<br />
Ceiling: 2 mg/m 3<br />
Component Bulgaria Croatia Ireland Cyprus Czech Republic<br />
Phenol<br />
TWA: 7.8 mg/m 3<br />
Skin notation<br />
Skin Notation<br />
TWA: 5 ppm 8 satima.<br />
TWA: 19 mg/m 3 8<br />
satima.<br />
Sodium hydroxide TWA: 2.0 mg/m 3 STEL: 2 mg/m 3 15<br />
minutama.<br />
TWA: 2 ppm 8 hr.<br />
TWA: 8 mg/m 3 8 hr.<br />
Skin<br />
Skin-potential for<br />
cutaneous absorption<br />
TWA: 2 ppm<br />
TWA: 7.8 mg/m 3<br />
TWA: 7.5 mg/m 3 8<br />
hodinách.<br />
Potential for cutaneous<br />
absorption<br />
Ceiling: 15 mg/m 3<br />
STEL: 2 mg/m 3 15 min TWA: 1 mg/m 3 8<br />
hodinách.<br />
Ceiling: 2 mg/m 3<br />
Component Estonia Gibraltar Greece Hungary Iceland<br />
Phenol<br />
Skin notation<br />
TWA: 2 ppm 8<br />
tundides.<br />
TWA: 7.8 mg/m 3 8<br />
tundides.<br />
Skin notation<br />
TWA: 2 ppm 8 hr<br />
TWA: 7.8 mg/m 3 8 hr<br />
skin - potential for<br />
cutaneous absorption<br />
STEL: 10 ppm<br />
STEL: 38 mg/m 3<br />
TWA: 5 ppm<br />
TWA: 19 mg/m 3<br />
SAFETY DATA SHEET<br />
STEL: 7.8 mg/m 3 15<br />
percekben.<br />
TWA: 7.8 mg/m 3 8<br />
órában.<br />
potential for cutaneous<br />
absorption<br />
TWA: 1 ppm 8<br />
klukkustundum.<br />
TWA: 4 mg/m 3 8<br />
klukkustundum.<br />
Skin notation<br />
Ceiling: 2 ppm<br />
Ceiling: 8 mg/m 3<br />
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Component Estonia Gibraltar Greece Hungary Iceland<br />
Sodium hydroxide<br />
TWA: 1 mg/m3 8<br />
STEL: 2 mg/m<br />
tundides.<br />
3<br />
TWA: 2 mg/m3 STEL: 2 mg/m3 15<br />
percekben.<br />
TWA: 2 mg/m3 STEL: 2 mg/m<br />
8<br />
órában.<br />
3<br />
Component Latvia Lithuania Luxembourg Malta Romania<br />
Phenol<br />
skin - potential for<br />
cutaneous exposure<br />
TWA: 2 ppm<br />
TWA: 7.8 mg/m 3<br />
TWA: 2 ppm<br />
TWA: 7.8 mg/m 3<br />
Skin notation<br />
STEL: 4 ppm<br />
STEL: 15.6 mg/m 3<br />
Sodium hydroxide TWA: 0.5 mg/m 3 Ceiling: 2 mg/m 3<br />
Possibility of significant<br />
uptake through the skin<br />
TWA: 2 ppm 8 Stunden<br />
TWA: 7.8 mg/m 3 8<br />
Stunden<br />
possibility of significant<br />
uptake through the skin<br />
TWA: 2 ppm<br />
TWA: 7.8 mg/m 3<br />
Skin notation<br />
TWA: 2 ppm 8 ore<br />
TWA: 7.8 mg/m 3 8 ore<br />
Component Russia - TWA Slovak Republic Slovenia Sweden Turkey<br />
Phenol<br />
TWA: 0.3 mg/m 3<br />
Skin notation<br />
STEL: 1 mg/m 3 vapor<br />
Potential for cutaneous<br />
absorption<br />
TWA: 2 ppm 8 urah<br />
TWA: 7.8 mg/m 3 8 urah<br />
Potential for cutaneous<br />
absorption<br />
Sodium hydroxide 2 TWA: 2 mg/m 3 8 urah<br />
inhalable fraction<br />
STEL: 2 mg/m 3 15<br />
minutah inhalable<br />
fraction<br />
STV: 2 ppm 15 minuter<br />
STV: 8 mg/m 3 15<br />
minuter<br />
LLV: 1 ppm 8 timmar.<br />
LLV: 4 mg/m 3 8 timmar.<br />
Skin notation<br />
LLV: 1 mg/m 3 8 timmar.<br />
inhalable dust<br />
CLV: 2 mg/m 3<br />
Skin notation<br />
TWA: 2 ppm 8 saat<br />
TWA: 7.8 mg/m 3 8 saat<br />
Biological limit values<br />
Component European Union United Kingdom France Spain Germany<br />
Phenol<br />
Total Phenol: 250 mg/g Phenol (with Phenol: 300 mg/L urine<br />
creatinine urine end of hydrolysis): 250 mg/g end of shift<br />
shift Creatinine urine end of<br />
shift<br />
Component Italy Portugal Netherlands Finland Denmark<br />
Phenol<br />
Total phenol: 1.3<br />
mmol/L urine end of the<br />
shift.<br />
Component Austria Switzerland Poland Norway Ireland<br />
Phenol<br />
Phenol: 250 mg/g<br />
creatinine urine end of<br />
shift<br />
Component Bulgaria Gibraltar Latvia Luxembourg Romania<br />
Phenol<br />
Phenol: 200 mg/L urine<br />
at the end of exposure<br />
or end of shift<br />
SAFETY DATA SHEET<br />
total Phenol: 50 mg/L<br />
urine end of shift<br />
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Component Slovak Republic Turkey<br />
Phenol<br />
Phenol: 200 mg/L urine<br />
end of exposure or<br />
work shift<br />
Derived No Effect Level (DNEL) No information available.<br />
Predicted No Effect Concentration<br />
(PNEC)<br />
No information available.<br />
Exposure controls<br />
Engineering Measures Ensure adequate ventilation, especially in confined areas<br />
Personal protective equipment<br />
Eye Protection Safety glasses with side-shields<br />
Hand Protection Protective gloves<br />
Skin and body protection Long sleeved clothing<br />
Respiratory Protection When workers are facing concentrations above the exposure limit they must use appropriate<br />
certified respirators<br />
Hygiene Measures Handle in accordance with good industrial hygiene and <strong>safety</strong> practice<br />
Environmental exposure controls No information available.<br />
9. PHYSICAL AND CHEMICAL PROPERTIES<br />
Physical State Liquid<br />
Appearance Amber<br />
pH 6.6 - 6.8<br />
Boiling Point/Range Not applicable<br />
Melting Point/Range No information available.<br />
Flash Point Not applicable<br />
Autoignition Temperature No information available.<br />
Reactivity<br />
Chemical Stability<br />
Stable under recommended storage conditions.<br />
Possibility of Hazardous Reactions<br />
Hazardous Polymerization No information available<br />
Hazardous Reactions . No information available.<br />
Conditions to Avoid<br />
Heat, flames and sparks<br />
10. STABILITY AND REACTIVITY<br />
SAFETY DATA SHEET<br />
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Incompatible Materials<br />
No materials to be especially mentioned.<br />
Hazardous Decomposition Products<br />
Carbon oxides. Nitrogen oxides (NOx). Hydrogen bromide .<br />
Information on Toxicological Effects<br />
Acute Toxicity<br />
11. TOXICOLOGICAL INFORMATION<br />
Product Information Product does not present an acute toxicity hazard based on known or supplied<br />
information<br />
Component Information<br />
Component LD50 Oral LD50 Dermal LC50 Inhalation<br />
Phenol 317 mg/kg ( Rat ) 525 mg/kg ( Rat )<br />
630 mg/kg ( Rabbit )<br />
316 mg/m3 1350 mg/kg ( Rabbit )<br />
( Rat ) 4 h<br />
Sodium hydroxide<br />
Chronic Toxicity<br />
Carcinogenicity The table below indicates whether each agency has listed any ingredient as a carcinogen<br />
Component IARC UK<br />
Phenol<br />
group 3<br />
Sensitization No information available.<br />
Mutagenic Effects No information available<br />
Reproductive Effects No information available.<br />
Developmental Effects No information available.<br />
Target Organs Liver Respiratory system Eyes Kidney Skin<br />
Endocrine Disruptor Information None known<br />
SAFETY DATA SHEET<br />
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Toxicity<br />
12. ECOLOGICAL INFORMATION<br />
Ecotoxicity effects Contains no substances known to be hazardous to the environment or that are not degradable<br />
in waste water treatment plants<br />
Component Freshwater Algae Freshwater Fish Microtox Water Flea<br />
Phenol 0.0188 - 0.1044 mg/L<br />
EC50 96 h<br />
46.42 mg/L EC50 = 96<br />
h<br />
187 - 279 mg/L EC50<br />
72 h<br />
4-7 mg/L LC50 96 h<br />
32 mg/L LC50 96 h<br />
Sodium hydroxide 45.4 mg/L LC50 96 h<br />
Persistence and degradability<br />
No information available<br />
Bioaccumulative potential<br />
No information available.<br />
Component<br />
Phenol<br />
Mobility in soil<br />
No information available.<br />
Results of PBT and vPvB assessment<br />
Other adverse effects<br />
No information available<br />
Waste treatment methods<br />
13. DISPOSAL CONSIDERATIONS<br />
SAFETY DATA SHEET<br />
EC50 21 - 36 mg/L 30<br />
min<br />
EC50 = 23.28 mg/L 5<br />
min<br />
EC50 = 25.61 mg/L 15<br />
min<br />
EC50 = 28.8 mg/L 5<br />
min<br />
EC50 = 31.6 mg/L 15<br />
min<br />
log Pow<br />
1.47<br />
10.2 - 15.5 mg/L EC50<br />
48 h<br />
4.24 - 10.7 mg/L EC50<br />
48 h<br />
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Revision Date 22-Nov-2011<br />
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Waste from Residues / Unused<br />
Products<br />
Dispose of in accordance with local regulations<br />
Contaminated Packaging Empty containers should be taken to local recyclers for disposal<br />
14. TRANSPORT INFORMATION<br />
IMDG/IMO Not regulated<br />
ADR Not regulated<br />
IATA Not regulated<br />
15. REGULATORY INFORMATION<br />
Safety, health and environmental regulations/legislation specific for the substance or mixture<br />
Take note of Directive 98/24/EC on the protection of the health and <strong>safety</strong> of workers from the risks related to chemical agents at work<br />
International Inventories<br />
Component EINECS ELINCS NLP TSCA DSL NDSL PICCS ENCS CHINA AICS KECL<br />
Phenol 203-632-7 - X X - X X X X X<br />
Sodium hydroxide 215-185-5 - X X - X X X X X<br />
Legend<br />
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory<br />
EINECS/ELINCS - European Inventory of Existing Commercial Chemical Substances/EU List of Notified Chemical<br />
Substances<br />
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List<br />
PICCS - Philippines Inventory of Chemicals and Chemical Substances<br />
ENCS - Japan Existing and New Chemical Substances<br />
CHINA - China Inventory of Existing Chemical Substances<br />
AICS - Inventory of Chemical Substances<br />
KECL - Existing and Evaluated Chemical Substances<br />
Chemical Safety Assessment<br />
SAFETY DATA SHEET<br />
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16. OTHER INFORMATION<br />
Full text of R-phrases referred to under sections 2 and 3<br />
R34 - Causes burns<br />
R35 - Causes severe burns<br />
R68 - Possible risk of irreversible effects<br />
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed<br />
R48/20/21/22 - Harmful: danger of serious damage to health by prolonged exposure through inhalation, in contact with skin and if<br />
swallowed<br />
Full text of H-Statements referred to under sections 2 and 3<br />
H301 - Toxic if swallowed<br />
H311 - Toxic in contact with skin<br />
H314 - Causes severe skin burns and eye damage<br />
H318 - Causes serious eye damage<br />
H331 - Toxic if inhaled<br />
H341 - Suspected of causing genetic defects<br />
H373 - May cause damage to organs through prolonged or repeated exposure<br />
Revision Date 22-Nov-2011<br />
Revision Summary Not applicable<br />
This <strong>safety</strong> <strong>data</strong> <strong>sheet</strong> complies with the requirements of Regulation (EC) No. 1907/2006<br />
Disclaimer<br />
The information provided on this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date<br />
of its publication. The information given is designed only as a guide for safe handling, use, processing, storage,<br />
transportation, disposal and release and is not to be considered as a warranty or quality specification. The information<br />
relates only to the specific material designated and may not be valid for such material used in combination with any other<br />
material or in any process, unless specified in the text.<br />
End of Safety Data Sheet<br />
SAFETY DATA SHEET<br />
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