More Questions and AnswerstfosflA uhoat DyesBy ALBERT C. jUDEOur popular contributor on the fascinating subject of animal geneticssustains the growing interest in the scientific aspects of cat breeding withthis sixth instalment in a fine new series. Readers are invited to submittheir'simple.problems to Mr. Jude who will be pleased to answer themfor the general interest in ensuing isrues.What facts are known about thegenetics of eye-colour?As far as I am aware, genetics o{eye-colour in cats has not beenu'orked on separately, but the follorvingobservations may be of interest.The colour of the eye dePends onthe pigment in the iris. In sorneeyes there is pigment on both sidesof the iris, on the side tacing theretina and on the side rvhich Iacesoutw-ard. Other eyes have Pigmentonly on the retinal side. In the latterclass there are the blues and cleargreys ; whiie the eyes rvith Pigmentin front of the iris also are browns,hazels or greens in various shades,according to the amount of pigmentpresent. Pigment is entirely absentin the eyes of albino animals, and asthe tiny l;loocl vessels are notobscured the iris takes on a pinkisha.ppearance.The instances in rvhich the pigmentic nresent in front of the iris areclominant to those in which it isabsent from tl-re front of the iris.Rrorvns hazcls ,,r orccns maled 1oco*harmo' i{ h-lprn.rron,r- oitp rh'.""fb".':b.'-.,.-recessive b1ue, but u'hen blues aremated together no individuais of thebrorrn class appear. Blues, hon'ever,may carry factors n'hich t'ill rnodifyl,rnrr ne trnr inctannp r {"^,^. -. "be cairied by blues rvhich t'il1 intensi[ythe bri)\rn pigment, and rn eyervith very little bron'n pigment matedrvith certain blues produces progenyof 3, deep brorvn, far deeper, maybe,than that in the e1'e of the brorvneyedparent,Orrite likclv there are other factorsu'hich modi{y brorvn, but not enoughis yet knou'n about the inheritance o{the shades to make possible any statementexcept that the heredity of thepigment in front of the iris behavesas though it rvere due to a Mendelianfactor. Th:t, hou'ever, is of importance,for it does suggest that presentsystems of classification of eye-colourszrre on rather an unsatisJa"ctory basis.Depth of co,our and shade is at presentthts accepted arrangemcnt, start.rvith the pa)e greys and ending uiththe brou'ns.The lighter qrecns arr place I amongthe blues. It is knorvn, hou.ever,thal Llrcs mav diffpr {rnm thp deenl,ro\\'ns in the absence o{ on}y onefactor, but the difierence betrveen ablue and a green rnav be :L dilTerenceclue to more than one factor.My queen recently had four normallyhealthy kittens and one rvhichwas bcrn with both eyes partiy open.WilI you piease explain this eye condition?In normal circumstances, the eyelidsof kittens are joined up beforebirth by a briclge of epjLhelium. 'lheL4
tittens are born in tbis condition andare unable to see simply because ttreiids completely covei the eyes. Norma]l-vthe eyeiids will open at about 'the seventh to tenth d4Y. In casesrvhere kittens are homozygous for thegene (" open eyes at birth ") the eyelidsdo not get comPletelY bridgedbe{ore birth, and these kittens aretherefore born with oPen eyes. Insome cases the lids maY be PartiYopen and in others ful1Y oPened. Inall cases the eyes are exPosed, andrvithout the usual lid movements toprotect against injury-including thatfrom early excessive light-damagemay be done rvhich could be impossibleto repair.Sometinies during the first twentvfourhours a slight haemorrhage takesplace in the lo'w'er lid and occasionallyin the upper one. SimultaneouslY, aslight haemorrhagic exudate is formedbetrveen the lids, rvhich may quicklydry up, Iilling the space betrveen thelids. This adheres to the cornea, but,as a rule, disappears rvhen kittens arefrom seven to fourteen daYs o d.\l'here it has adhered to the cornea abulging often remails for some time,but later this often disappears. Quitefrequently, hou'ever, kittens soafiected retain some opacities in thecornea throughout 1ife.Readets have asked for advicewhich might help in selecting suitablestuds for their queens,As the queens concerned are not ailof one breed, this ansrver is framedin zr lay mos'c likely to assist allreaders similarly interested..Undoubtedly, I s'ould be \-eryn'rong if I did not suggest that healthshould be the first consideration s'henchoosing an\ animal for 1.1eedingpurposes. Very definitell this mustbe the cr -e rr here stock is beingselected to lorm the foundation of astrain. No matter how near to Perfectionof colour or form these initialanimals may be, their value tvi1l havebeen very littie if theY Possessedu,eaknesses in ttre factors Ior healthand reproductive caPacitY.The fancier x'ho takes heed thisway can be successful' If he ignoresthe point of " health first," then hewill not be successful. The first need,therefore, is to estabiish the fact thatany prospective stud cornes from aline oI healthy qnd ful1Y fertiieanimals. Get to know the Performanceof his ancestors, especially thoseon the rnale side.The next consideration will be thatthe colour and type of the studmatches up to the colour and tYPe ofthe queen to be mated, rememberingthat all the individual characteristicsof outward bodily make-up constitute" type." The aim must be tocounteract any faiiings !n the queenby using a. male definitely strong inthose particular failings. For instance,should the queen have ratherpoor eye-colour, choose a male withreally good eye-colour. Each separatecharacteristic must be consideredin this rvay, but the greatest failingmust al*'ays have prior attention'\,Iake certain at mating time ttrat thestud is in tight coat. In the case oflonghaired cats the length of coat atthe time of mating is not important'provided it is knorvn that when inful1 c.oat good length of coat iscarried.Obviously, the most likely place tochoose el suitable stud is at a show,n,here sevetal likely males can be seenand compared. Tt u'il1 not necessarilylre the rvinnins male rvhich rtill bethe m,sr suitabl'{or a, particularmr f in q Th. celee tinn rur duy rrra L-ino mrci he made on the basis ofcomparison u'ith the queen point bypoint.I:Iaving selected the 1ikely. stud, itis nou' vital to have proof that he iscanahrc of renrodrrrinp himsell in hisprogeny. We often talk of " throwingbatk," and this is the reason whysome males have the ability of breedingyoungsters rvhictr may be much15