List of used abbreviations - RosDok - Universität Rostock

More documents

Recommendations

Info

1492 (w), 1437 (s), 1386 (s), 1354 (m), 1319 (s),1230 (s), 1198 (m),. 1142 (s), 1014 (m), 776 (m), 767 (m), 702 (s); cm−1; GC-MS (EI, 70 eV): m/z (%): 288 (M + , 100), 245 (9), 244 (38), 216 (11), 215 (54), 213 (8), 202 (3), 189 (3), 152 (5), 139 (3), 122 (6), 113 (4), 107 (16), 94 (7). HRMS (EI): calcd for C20H16O2 [M + ]: 288.10632, found 288.105768. Me OH O 5'-Hydroxy-6'-methyl-[1,1';3',1'']terphenyl-4'-carboxylic acid methyl ester (17c); Starting with 15 (453mg, 1.65 mmol), 16c ( 444mg, 1.5 mmol), TiCl4 (0.2ml, 1.65 mmol) and CH2Cl2 (9ml), 17c was isolated as a gummy compound (222.9mg, 37%); 1 H NMR (300 MHz, CDCl3): δ = 2.12 (s, 3H, CH3), 3.39 (s, 3H, OCH3), 6.66-7.29 (m, 11H, ArH), 11.05 (s, 1H, OH); 13 C NMR (75 MHz, CDCl3): δ = 13.7 (CH3), 52.1 (OCH3), 110.4, 123.7, 124.2, 127.1, 127.6 (ArCH), 127.9, 128.0, 128.5 (2C ArCH), 141.2, 141.9, 143.3, 145.3, 144.5, 147.5, 160.6 (ArCH), 172.3 (C); IR (neat): ν̃ = 3426 (m), 3087 (w), 3052 (m), 3028 (m), 2947 (m), 1664 (s), 1597 (m), 1556 (m), 1493 (w), 1437 (s), 1386 (s), 1359 (m), 1320 (s), 1256 (s), 1230 (s), 1198 (m),. 1143 (s), 1014 (m), 776 (m), 767 (m), 702 (s); cm−1; GC-MS (EI, 70 eV): m/z (%):318 (M+, 100), 300 (20), 288 (4), 276 (3), 245 (9), 244 (38), 216 (11), 215 (54), 213 (8), 202 (9), 189 (7), 152 (3), 139 (9), 122 (8), 113 (6), 107 (16), 94 (7). HRMS (EI): calcd for C21H18O3 [M + ]: 318.10654, found 318.109762. OMe 90
Refrences 1. Handbook of Chemistry and Physics, 81st Edition CRC Press ISBN 0-8493- 0481-4. 2. Cavallito, C. J.; Bailey, J. H. J. Am. Chem. Soc., 1944, 66, 1950. 3. http://www.phytochemicals.info/phytochemicals/allicin.php 4. Fleischauer, A. T.; Arab L. J. Nutr. 2001, 131, 1032. 5. Herman-Antosiewicz, A.; Singh, S. V. Mutat. Res 2004, 555, 121. 6. Milner, J. A. J Nutr 2001, 131, 1027. 7. Pinto, J. T.; Lapsia, S.; Shah, A.; Santiago, H.; Kim, G. Antiproliferative effects of garlic-derived and other allium related compounds. In: Go VLW, editor. Nutrition and cancer prevention: new insights into the role of phytochemicals. Advances in experimental medicine and biology, 492, chapter 8. New York: Kluwer Academic/Plenum Publishers; 2001. p. 83–106. 8. Wu, X.; Kassie, F.; Mersch-Sundermann, V. Mutat. Res. 2005, 589, 81. 9. See for example: Mori, Y.; Taneda, S.; Hayashi, H.; Sakushima, A.; Kamata, K.; Suzuki, A. K.; Yoshino, S.; Sakata, M.; Sagai, M.; Seki, K.-i. Biol. Pharm. Bull. 2002, 25, 145. 10. (a) Davidson, B. S.; Molinski, T. F.; Barrows, L. R.; Ireland, C. M. J. Am. Chem. Soc. 1991, 113, 4709. (b) Behar, V.; Danishefsky, S. J. J. Am. Chem. Soc. 1993, 115, 7017. (c) Toste, F. D.; Still, I. W. J. J. Am. Chem. Soc. 1995, 117, 7261. 91
Page 1 and 2:
Synthesis of functionalized 2-(aryl
Page 3 and 4:
The ink of the scholar is more holy
Page 5 and 6:
Affectionately Dedicated to “All
Page 7 and 8:
Table of Contents 03 List of used a
Page 9 and 10:
RCM Ring Closing Metathesis TBAI Te
Page 11 and 12:
humans: 1) the thiomethyl of methio
Page 13 and 14:
Chart 3. Structure of sumatriptan S
Page 15 and 16:
disulfide (DADS) and diallyl sulfid
Page 17 and 18:
1. Synthesis of functionalized 2-(a
Page 19 and 20:
3-Arylthio-1-trimethylsilyloxy-1,3-
Page 21 and 22:
under kinetic reaction control, by
Page 23 and 24:
l a u 4-FC6H4 H Me H 40 m a v 4-FC6
Page 25 and 26:
Table 2. Synthesis of thioxanthones
Page 27 and 28:
3a O OSiMe 3 O OMe + Me Me Cl 3TiO
Page 29 and 30:
Table 3. Synthesis of 8a-x 3 7 8 Ar
Page 31 and 32:
Cl + SPh OSiMe 3 3a 9 O OMe O O H i
Page 33 and 34:
solution. The use of an excess (1.5
Page 35 and 36:
Table 4. Synthesis of 12a-r 3 11 12
Page 37 and 38:
2.3 Conclusion In conclusion, I hav
Page 39 and 40:
aromatization). An unseparable 1:2
Page 41 and 42:
Table 5. Synthesis of arenes 14a-l
Page 43 and 44: 3.3 Conclusion In conclusion, I hav
Page 45 and 46: Mass Spectroscopy: AMD MS40, AMD 40
Page 47 and 48: 131.0 (ArCH), 132.7, 134.0, 135.9,
Page 49 and 50: (EI, 70 eV): m/z (%): 380 (100), 21
Page 51 and 52: (m), 1490 (m), 1434 (m), 1383 (w),
Page 53 and 54: 15.4, 16.9, 18.9 (CH3), 28.3 (CH2),
Page 55 and 56: (C). IR (neat): ν̃ = 2945 (w), 29
Page 57 and 58: 948 (w) 853 (m), 803 (m), 751 (m),
Page 59 and 60: 135.4, 139.2, 143.8, 146.5, 182.2 (
Page 61 and 62: Me S O Me Ph Br Methyl 4-methyl-5-(
Page 63 and 64: 35 Cl, 37 Cl, 61), 430 (M + , 35 Cl
Page 65 and 66: ArH). 13 C NMR (62 MHz, CDCl3): δ
Page 67 and 68: Me S O Me Me Methyl 4,6-dimethyl-5-
Page 69 and 70: S Methyl 4-methyl-5-(2-bromoethyl)-
Page 71 and 72: (CH2CH3), 33.3 (CH2), 40.1 (CH2), 5
Page 73 and 74: Me 3,4-Dimethyl-2-phenylsulfanyl-be
Page 75 and 76: Me 3,4-Dimethyl-2-(p-tolylsulfanyl)
Page 77 and 78: OCH3), 7.08-7.17 (m, 7H, Ar); 13 C
Page 79 and 80: (w), 750 (s), 732 (s), 688 (s), 650
Page 81 and 82: 35 Cl 35 Cl, 100), 359 (26), 357 (3
Page 83 and 84: 2924 (w), 2853 (w), 1728 (s), 1712
Page 85 and 86: Me 3-Hydroxy-5-(4-methylphenylsulfa
Page 87 and 88: Et 3-Hydroxy-5-(4-ethylphenylsulfan
Page 89 and 90: (13), 264 (13), 262 (36) ,260 (12),
Page 91 and 92: MS (EI, 70 eV): m/z (%) = 337 (16),
Page 93: OH O 5'-Hydroxy-[1,1';3',1'']terphe
Page 97 and 98: 20. For a review of [3+3] cyclizati
Page 99 and 100: Nationality Pakistan Place of Birth
Page 101 and 102: Publications 1. Inam Iqbal, Muhamma
Page 103 and 104: Tetrahedron 2007, 63, 12562-12575.
show all

List of used abbreviations - RosDok - Universität Rostock

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?