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List of used abbreviations - RosDok - Universität Rostock

List of used abbreviations - RosDok - Universität Rostock

List of used abbreviations - RosDok - Universität Rostock

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Chart 3. Structure <strong>of</strong> sumatriptan<br />

Sumatriptan (Chart 3.) represents an sufonamide-substituted indole which is an<br />

important modern drug for the treatment <strong>of</strong> migraine. Some organosulfur compounds<br />

in the environment, are generated as minor by-products <strong>of</strong> industrial processes such<br />

as the manufacture <strong>of</strong> plastics and tires.<br />

Because the role <strong>of</strong> elemental sulfur in human nutrition has not been studied<br />

extensively, it is the purpose <strong>of</strong> this introduction to emphasize the importance <strong>of</strong> this<br />

element for humans and to discuss the therapeutic applications <strong>of</strong> sulfur compounds<br />

in medicine. Sulfur is the sixth most abundant macromineral in breast milk and the<br />

third most abundant mineral based on percentage <strong>of</strong> total body weight. The sulfur-<br />

containing amino acids (SAAs) are methionine, cysteine, cystine, homocysteine,<br />

homocystine, and taurine. Dietary SAA analysis and protein supplementation may be<br />

indicated for vegan athletes, children, or patients with HIV, because <strong>of</strong> an increased<br />

risk for SAA deficiency in these groups. Methylsulfonylmethane (MSM), a volatile<br />

component in the sulfur cycle, is another source <strong>of</strong> sulfur found in the human diet.<br />

9

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