Referat Dr. med. C. Caflisch
Referat Dr. med. C. Caflisch
Referat Dr. med. C. Caflisch
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Leavitt et al. 2000When „Enough“ Is Not Enough: New Perspectives onOptimal Methadone Maintenance DoseThe Mount Sinai Journal of Medicine Vol. 67Some methadone maintenance treatment (MMT) programsprescribe inadequate daily methadon doses. Patient complain ofwithdrawal symptoms and continue illicit opioid use, yetpractitioners are reluctant to increase doses above certainarbitrary thresholds.New research suggests that doses ranging from 120mg/d tomore than 700mg/d, with correspondingly higher serummethadone levels, may be optimal for many patients.
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