Referat Dr. med. C. Caflisch

Authors’ conclusionsAll included studies showed that gradual taper was preferable toabrupt discontinuation. The results of this systematic reviewpoint to the potential value of carbamazepine as an effectiveintervention for benzodiazepine gradual taper discontinuation.But, larger controlled studies are needed to confirmcarbamazepine’s potential benefit, to assess adverse effects andto identify when its clinical use might be most indicated. Othertreatment approaches to benzodiazepine discontinuationmanagement should be explored (antidepressants,benzodiazepine receptors modulator).