Referat Dr. med. C. Caflisch

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The purpose of the study was to assess prevalence of benzodiazepine use in theSwiss adult population and to assess on benzodiazepine prescription patterns ofphysicians in domiciliary practice.Study design A retrospective, population-based cross-sectional study with520 000 patients covering a 6-month period.Methods We estimated the prevalence, amount and duration of benzodiazepineuse using a pharmacy dispensing database.
Results Of all patients, 9.1% (n= 45 309) received at least one benzodiazepineprescription in the 6-month period. Most persons receiving benzodiazepineprescriptions were women (67%), and half of all patients were aged 65 or older. Of45 309 patients with benzodiazepine prescriptions, 44% (n =19 954) had one singleprescription, mostly for a short period ( 90 days), and in lower than therecommended or within the recommended dose range.In patients with long-term use (n= 25 354), however, 1.6% (406) had benzodiazepineprescriptions in extremely high doses. The sample of patients with repeatedprescriptions allowed an estimation of a benzodiazepine use of 43.3 daily defineddoses per 1000 inhabitants in Switzerland.Conclusions Benzodiazepine prescriptions were appropriate for most patients andthus were prescribed in therapeutic doses, as indicated in the treatment guidelines.On the other hand, our survey showed that 1.6% of the patients had prescriptions forlong time periods at very high doses, indicating an abuse or dependence onbenzodiazepines in this subgroup.Int Clin Psychopharmacol 22:292–298 c 2007 Lippincott Williams & Wilkins.
Page 1 and 2: Zentrum für Abhängigkeitserkranku
Page 4 and 5: Geschichte der PsychopharmakaMorphi
Page 6: Librium wird als erstes Medikament
Page 9: Leavitt et al. 2000When „Enough
Page 14: Drug Alcohol Depend. 1993 May;32(3)
Page 19 and 20: Eine Abhängigkeit von Benzodiazepi
Page 21 and 22: Index · Contents · Introduction
Page 24: Authors’ conclusionsAll included
Page 27 and 28: Australian and New Zealand Journal
Page 29 and 30: METHODE (1)Benzodiazepinabhängige
Page 31 and 32: RESULTATE (1)Alle Patienten bis auf
Page 33 and 34: DISKUSSION (1)Die Substitution mit
Page 38 and 39: Der „Seresta-Notstand“Sommer 20
Page 41 and 42: Der „Seresta-Notstand“Sommer 20
Page 43 and 44: SCHLUSSBEMERKUNGENStudien zur Subst

Referat Dr. med. C. Caflisch

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