EEBA Program (PDF/3MB) - EEBA - Annual Meeting

RECURRENCE OF ANTERIOR CORNEAL DYSTROPHIES AFTER KERATOPLASTYP. Sauvageot, I. Rodriguez, A. Buigues, J. Alvarez de ToledoCentro de Oftalmología Barraquer, SpainPurpose: To describe the rate of simple recurrence (SR) and/or clinically significant recurrence (CR) ofdifferent kinds of anterior dystrophies in donor corneas after keratoplasty.Methods: Retrospective case series of patients who underwent keratoplasty for anterior dystrophiesfrom 1954 to 2008 with a minimum follow-up time of three years. Kaplan Meier survival curves werecalculated for both parameters (SR and CR) to demonstrate recurrence through time.Results: A total of 109 eyes of 66 patients were included: 8 cases of Bowman´s dystrophy (6 eyes withCDRB/Reis Bucklers and 2 eyes with CDTB/Thiel Behnke), 19 cases of CDG/Granular, 53 cases of CDL/Lattice and 29 cases of CDM/Macular. The median follow-up time for each kind of dystrophy variedfrom 75 months (6.25 years) to 180 months (15 years). The survival function for simple recurrencewas significantly higher (376.2 months/31 years) for cases of CDM, as compared to those dystrophiesrelated to the keratoepithelin gene : CDRB =177.6 months, CDL=168 months and CDG =89.2 months.Clinically significant recurrence (CR) was noted predominantly in cases of CDL and CDG.Conclusions: Keratoplasty (whether penetrating or lamellar) is an effective treatment for cases ofanterior dystrophies, when visual axis is affected or when other less invasive treatment modalities fail.The statistically significant difference in survival time of recurrence after keratoplasty for the differentkinds of anterior dystrophies coincides with literature and may help us in prognosticating the besttreatment option for each individual case.XXV ANNUAL MEETING OF THE EUROPEAN EYE BANK ASSOCIATION Zagreb, Croatia 18/19 January 2013 65