EEBA Program (PDF/3MB) - EEBA - Annual Meeting

ANATOMICAL AND FUNCTIONAL RESULTS OF PENETRATING QUERATOPLASTY IN PATIENTSWITH ACANTAMOEBA-KERATITISJ. Rosandic, M. Fideliz de la Paz, C. D. P. de los Rios, J. Alvarez de ToledoCentro de Oftalmologia Barraquer, SpainPurpose: to describe the anatomical and functional outcomes of patients who underwentpenetrating keratoplasty for acanthamoeba keratitis.Methods: This is a retrospective study on 16 eyes of 16 patients who underwent penetratingkeratoplasty for acanthamoeba keratitis at our eye center from 1995 -2009. Data on preoperativefactors like use of contact lenses, visual acuity and treatment, as well as post-operative data likegraft diameter, intraocular pressure, complications and treatment were evaluated. Graft survival wasevaluated with the Kaplan-Meier life table analysis and comparisons were performed using Log-rank.Results: 68% of the patients were women, and mean age was 35.5 (+/- 12.6, range: 13-56) years.68% reported use of contact lens prior to infection. 6.8% reported ocular trauma as a possible causeof the keratitis. In the post-operative follow-up, 56% developed glaucoma, 75% developed cataract,12.5% had retinal detachment and 6.2% ended up in endophthalmitis. 9 patients required a secondpenetrating keratoplasty due to graft failure, 1 patient required a third keratoplasty. 43% maintaineda clear graft during the first year post-operation. 2 patients had recurrence of acanthamoeba keratitisonto the graft.Conclusions: Penetrating keratoplasty is a viable treatment option in patients with acanthamoebakeratitis who do not respond to medical treatment. However, graft survival has guarded prognosis dueto the aggressiveness of the infection, as well as the medical treatment which has to be continued inthe post-operative period. Post-operative glaucoma and cataract are post-operative complicationswhich may condition the anatomical and functional success of the graft.62