SPEH948990 51835-51-9 SPED289070 212321 ... - Spectra 2000 Srl

Products for Innovative ResearchCatalogue NumberSPET947660Chemical NameTylosin 3-AcetateMol. FormulaCAS No.63409-10-9AppearanceOMeMeHO OMeO OOMe OMeOMeMe OMeN MeHOO O MeOAcO OOHMeOHMeC 48 H 79 NO 18Off-White SolidMol Weight.SolubilityStorage958.14DMSO, Methanol-20˚C FreezerApplication notesA new acyl derivative of Tylosin (T947650) produced by microbial transformation.Catalogue Number CAS No.SPEA161232Chemical Name4-Acetaminophen-d3 Sulfate Potassium SaltMol. FormulaAppearanceKO 3 SONHOCD 3C 8 H 5 D 3 KNO 5 SMol Weight.272.33White SolidSolubilityDMSO, WaterStorageRefrigeratorApplication notesA labelled metabolite of Acetaminophen.Catalogue NumberSPEF322520Chemical NameFexofenadinoneMol. FormulaCAS No.76811-98-8AppearanceHO 2 CMe MeC 32 H 37 NO 4Off-White SolidMol Weight.SolubilityStorage499.64DMSOHygroscopic, Refrigerator, UnderApplication notesThe oxo analogue of Fexofenadine (F322470); H1-histamine receptor antagonist and an activemetabolite of Terfenadine (T114500).ONPhPhOH

Products for Innovative ResearchCatalogue NumberSPEC184112Chemical NameL-Carnitine- 13 CMol. FormulaCAS No.Appearance- O13 COOHN + Me 3C 13 6 CH 15 NO 3Mol Weight.SolubilityStorage162.19Application notesEssential cofactor of fatty acid metabolism; required for the transport of fatty acids through the innermitochondrial membrane. Synthetized primarily in the liver and kidney; highest concentrations found inheart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado.Catalogue NumberSPEA603405Chemical Name(S)-Amino CarnitineMol. FormulaCAS No.125377-87-9AppearanceMeMeN + COO -Me NH 2C 7 H 16 N 2 O 2Off-White SolidMol Weight.SolubilityStorage160.21WaterHygroscopic, Refrigerator, UnderApplication notesAn inhibitor of fatty acid oxidation. Aminocarnitine acts as a hypoglycemic and antiketogeniccompound. It alters lipidic metabolism by inhibiting carnitine acetyltransferase (CAT) and carnitinepalmitoyltransferase (CPT).

Products for Innovative ResearchCatalogue NumberSPEC242560Chemical NameΔ 2 -Cefcapene PivoxilMol. FormulaCAS No.AppearanceH 2 NNSOH HS O NHN2HN OOOCH 3O O O C(CH 3 ) 3C 23 H 29 N 5 O 8 S 2Mol Weight.567.64Off-White to Pale Yellow SolidSolubilityMethanolStorage-20˚C FreezerApplication notesCefcapene Pivoxil (C242550) derivative. Δ2-Cephalosporins are potentially related compounds incephalosporin antibacterial compounds.Catalogue Number CAS No.SPEL470495 138584-35-7Chemical NameLosartan N2-Glucuronide (90%)Mol. FormulaAppearanceH 3 CHO 2 CHOHOHOClNOHNNNO N NC 28 H 31 ClN 6 O 7Mol Weight.599.03SolubilityStorageApplication notesA metabolite of Losartan (L470500).Catalogue NumberSPEE975065Chemical NameEzetimibe KetoneMol. FormulaC 24 H 19 F 2 NO 3Mol Weight.407.41CAS No.191330-56-0AppearanceWhite to Off-White SolidSolubilityChloroformOFStorage-20˚C FreezerONOHFApplication notesPhase-I metabolite of Ezetimibe (E975000).

SPEP206500CAS No.149-29-1OHPatulinOOOC 7 H 6 O 4Off-White to Pale Orange Solid154.12Acetone, MethanolHygroscopic, -20°C Freezer, UnderApplication notesPatulin (PAT), a mycotoxin produced by certain species of Penicillium, Aspergillus, and Byssochlamys,is mainly found in ripe apple and apple products. Patulin-induced genotoxicity and modulation ofglutathione in Hep G2 cells. Patulin is an antibiotic. Patulin-induced nephropathy and gastrointestinaltract malfunction have been demonstrated in several animal models. The oral LD50 value of patulinranges between 29 and 55 mg/kg body weight in rodents and 170 mg/kg body weight in poultry. TheW ld H lth O i ti id t li t t i d t bli h d f t l l f t li i lCatalogue Number CAS No.NH 2HOSPEH94665215 NChemical Name5-Hydroxy-2’-deoxycytidine- 13 C, 15 N 2Mol. FormulaAppearance13C 8 CH 13 N 15 N 2 O 5Off-White SolidMol Weight.SolubilityStorage246.20Water-20˚C FreezerApplication notes5-Hydroxy-2’-deoxycytidine- 13 C, 15 N 2 is the Isotope labelled analogue of 5-Hydroxy-2’-deoxycytidine(H946650), a substrate for uracil DNA N-glycosylase and has been used to study the oxidation of DNAdue to exposure to reactive oxygen species.HOOHO13 15 CNO

Products for Innovative ResearchCatalogue Number CAS No.SPEH102490 64924-67-0Chemical NameHalofuginone HydrobromideMol. FormulaAppearanceBrClNONOHNOHHBrC 16 H 18 Br 2 ClN 3 O 3 White to Off-White SolidMol Weight.SolubilityStorage495.59DMSO, Water-20˚C Freezer, Under InertApplication notesHalogenated derivative of Febrifugine. Used as an antiprotozoal (coccidiostat).

Products for Innovative ResearchCatalogue NumberSPEA108492Chemical NameAbiraterone-d4Mol. FormulaC 24 H 27 D 4 NOMol Weight.353.53CAS No.AppearanceWhite to Off-White SolidSolubilityMethanolHOStorageRefrigeratorApplication notesLabelled Abiraterone (A108490). A steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor(CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment ofandrogen-dependent prostate cancer.MeHNDMeHHDDDCatalogue NumberSPET795320Chemical Name3,3',5-Triiodo Thyroacetic AcidMol. FormulaCAS No.51-24-1AppearanceHOIIOICO 2 HC 14 H 9 I 3 O 4Mol Weight.621.93White to Off-White SolidSolubilityDMSO, MethanolStorageRefrigeratorApplication notesThyroid hormone analogue. A potent Thyroxine impurity.

Products for Innovative ResearchCatalogue NumberSPEC256700Chemical NameCephaelineMol. FormulaC 28 H 38 N 2 O 4Mol Weight.466.61CAS No.483-17-0AppearanceOff-White to Pale Yellow SolidSolubilityChloroform, MethanolH 3 COH 3 COStorage-20°C FreezerHNHNHCH 3OCH 3OHApplication notesHas been used as an emetic and expectorant.Catalogue NumberSPEH954010Chemical Name5-HydroxysulfapyridineMol. FormulaCAS No.50930-57-9AppearanceHONNH 2HN SO OC 11 H 11 N 3 O 3 SMol Weight.265.29Yellow SolidSolubilityDMSO, MethanolStorageRefrigeratorApplication notes5-Hydroxysulfapyridine is a hydroxy metabolite of Sulfapyridine (S699083), an antibacterial agent usedin the treatment of dermatitis and herpetiformis.Catalogue NumberSPEL466507Chemical Name(R)-Linezolid-d3Mol. FormulaC 16 H 17 D 3 FN 3 O 4Mol Weight.340.36CAS No.AppearanceBrown SolidSolubilityChloroform, Ethyl AcetateONFStorageRefrigeratorApplication notesLabelled analogue of (R)-Linezolid, an enatiomeric impurity of Linezolid (L466500).ON O HNCD3HO