Advanced Cell Biology. Lecture 31 - Materials of Alexey Shipunov
Advanced Cell Biology. Lecture 31 - Materials of Alexey Shipunov Advanced Cell Biology. Lecture 31 - Materials of Alexey Shipunov
Membrane transportSignaling in nerve cellsCa 2+ channels and synapses◮ Synapse converts electrochemical signal to pure chemical◮ Depolarization of presynaptic membrane will cause Ca 2+channels to open, increase calcium concentration inside cell andinitiate fusion of synaptic vesicles to the membrane◮ Fusion should be quickly stopped (one of mechanisms isretro-neurotransmitters like endocannabinoids)Shipunov (MSU) Advanced Cell Biology. Lecture 31 April 17, 2013 18 / 24
Membrane transportSignaling in nerve cellsTransmitter-gated channels◮ Neurotransmitter (small molecule of given configuration) crossessynaptic cleft and binds to ligand-gated receptors◮ In synaptic junctions between nerve and muscle cells,acetylcholine neurotransmitter will bind to receprots inpostsynaptic muscle cells◮ Neurotransmitters need to be quickly destroyed (many poisonslike kurare will block this destruction)Shipunov (MSU) Advanced Cell Biology. Lecture 31 April 17, 2013 19 / 24
- Page 1 and 2: Advanced Cell Biology. Lecture 31Al
- Page 3 and 4: OutlineQuestions and answersMembran
- Page 5 and 6: Questions and answersPrevious final
- Page 7 and 8: Membrane transportMembrane potentia
- Page 10 and 11: Membrane transportSignaling in nerv
- Page 12 and 13: Membrane transportSignaling in nerv
- Page 14 and 15: Membrane transportSignaling in nerv
- Page 16 and 17: Membrane transportSignaling in nerv
- Page 18 and 19: Membrane transportSignaling in nerv
- Page 22 and 23: Membrane transportSignaling in nerv
- Page 24 and 25: Membrane transportSignaling in nerv
- Page 26 and 27: Membrane transportSignaling in nerv
Membrane transportSignaling in nerve cellsTransmitter-gated channels◮ Neurotransmitter (small molecule <strong>of</strong> given configuration) crossessynaptic cleft and binds to ligand-gated receptors◮ In synaptic junctions between nerve and muscle cells,acetylcholine neurotransmitter will bind to receprots inpostsynaptic muscle cells◮ Neurotransmitters need to be quickly destroyed (many poisonslike kurare will block this destruction)<strong>Shipunov</strong> (MSU) <strong>Advanced</strong> <strong>Cell</strong> <strong>Biology</strong>. <strong>Lecture</strong> <strong>31</strong> April 17, 2013 19 / 24
Change language