Advanced Cell Biology. Lecture 31 - Materials of Alexey Shipunov
Advanced Cell Biology. Lecture 31 - Materials of Alexey Shipunov Advanced Cell Biology. Lecture 31 - Materials of Alexey Shipunov
Membrane transportSignaling in nerve cellsAction potential and Na + channels◮ Depolarization of neighbor region is a stimulus which opens Na +channels and initiate rapid movement of these ions into cell◮ Membrane potential changes from ≈–60 to ≈+40 mV and Na +channels inactivate◮ Then, voltage-gated K + channels are open, K + leaks out of celland potential (but not ions!) restores◮ Then, Na + channels close and Na + /K + pump restore ionconcentration to default valuesShipunov (MSU) Advanced Cell Biology. Lecture 31 April 17, 2013 12 / 24
Membrane transportSignaling in nerve cellsAction potentialShipunov (MSU) Advanced Cell Biology. Lecture 31 April 17, 2013 13 / 24
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Membrane transportSignaling in nerve cellsAction potential<strong>Shipunov</strong> (MSU) <strong>Advanced</strong> <strong>Cell</strong> <strong>Biology</strong>. <strong>Lecture</strong> <strong>31</strong> April 17, 2013 13 / 24