Advanced Cell Biology. Lecture 31 - Materials of Alexey Shipunov
Advanced Cell Biology. Lecture 31 - Materials of Alexey Shipunov
Advanced Cell Biology. Lecture 31 - Materials of Alexey Shipunov
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Membrane transportSignaling in nerve cellsAction potential and Na + channels◮ Depolarization <strong>of</strong> neighbor region is a stimulus which opens Na +channels and initiate rapid movement <strong>of</strong> these ions into cell◮ Membrane potential changes from ≈–60 to ≈+40 mV and Na +channels inactivate◮ Then, voltage-gated K + channels are open, K + leaks out <strong>of</strong> celland potential (but not ions!) restores◮ Then, Na + channels close and Na + /K + pump restore ionconcentration to default values<strong>Shipunov</strong> (MSU) <strong>Advanced</strong> <strong>Cell</strong> <strong>Biology</strong>. <strong>Lecture</strong> <strong>31</strong> April 17, 2013 12 / 24
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