Tour-de-Force

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Tour-de-Force: Interplay between Mitochondria and Cell Cycle Progression Fall 2007Author’s PageProject 1: Regulation of Cell Cycle Progression Through Mitochondrial ROS ProductionS.E. BoschH.T. CaylakK.K. DijkstraN.C. FrenkelD.D.J.J. van HooijdonkJ.C. MostertProject 2: Checking the Checkpoint: Understanding the Influence of AMPKA.M. AlbersL.M. HamerslagE. KhalilH.M. MelseM. SilanikoveM.J.K. StolteJ. WalkProject 3: Mitochondrial Biogenesis during the Cell CycleB.B.F. EidhofI. FlamentS.L. GilesJ. GunkelW.P. van KlinkenJ.A.J.M. PijnenburgProject 4: Mitofusin 2 and the Cell CycleJ. ClausS.J.H. DiederenL. HussaartsS. KampsA. MoussaA. SchierenbergSCI 332 Advanced Molecular Cell Biology Research Proposal 2
Tour-de-Force: Interplay between Mitochondria and Cell Cycle Progression Fall 2007Table of ContentsAuthor’s page 2Acknowledgements 4General introduction 5Project 1: Regulation of Cell Cycle Progression Through Mitochondrial ROS Production 9Introduction 10Background 11Research Proposal 16Conclusion 30Proposed Costs 32Proposed Timeline 33References 34Project 2: Checking the Checkpoint: Understanding the Influence of AMPK 36Introduction 37Background 38Research Proposal 43Proposed Costs 52Proposed Timeline 52Conclusion 53References 54Project 3: Mitochondrial Biogenesis during the Cell Cycle 57Introduction 58Background 59Research Proposal 64Proposed Costs 69Proposed Timeline 69Discussion 70References 71Project 4: Mitofusin 2 and the Cell Cycle 73Introduction 74Background & Research Proposal 77Discussion 89Proposed Costs 90Proposed Timeline 90Acknowledgements 91References 92General Conclusion 94Appendix A 95Appendix B 102Appendix C 111Appendix D 112Appendix E 116SCI 332 Advanced Molecular Cell Biology Research Proposal 3
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