Trauma Guideline Manual - SUNY Upstate Medical University

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42____________ Trauma Guideline ManualUpstate Medial University Trauma CenterOPERATIONAL GUIDELINES: BLOOD AND BLOOD PRODUCT TRANSFUSIONOBJECTIVE:To provide a guideline for the transfusion of blood and blood products into trauma patients.DEFINITIONS:1. Packed red blood cells: A blood product that contains red blood cells with most of theplasma eluted off. The average hematocrit of PRBC’s is 70%. Each unit of PRBC’s (220 ml)will raise the hematocrit by about 3%.2. Fresh frozen plasma: A blood product that contains fresh components of plasma, includingcolloid proteins and clotting factors. Note that some FFP is “cryo-poor” and may have asmuch as 50% of the Factor VIII depleted.3. Platelets: A blood product that contains primarily platelets suspended in a small amount ofplasma. Each unit of plasma will raise the platelet count by about 10,000.4. Cryoprecipitate: A blood product component of plasma that primarily contains Factor VIII,Factor V and fibrinogen. This is the best blood product for treatment of low fibrinogen (
Trauma Guideline Manual______________Upstate Medical University Trauma Center43ii.Obvious major bleeding during transport with subsequent impending cardiac arrestdue to anemia (not hypovolemia).b. Risks: about 1.3% of all patients will have a clinically significant antibody other thananti-D and 70% of these will be women. These patients are at risk for delayedhemolytic transfusion reaction.The following guidelines apply to patients not receiving blood products via the MTP.5. Uncross-matched, ABO, Rho(D) compatible blood: available in 10 minutes after samplereceived in the Blood Bank; requires signed release form.a. Indications:i. Hypotensive; hematocrit
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