Application for the Reassessment of a Hazardous Substance under ...

With full-body chemical resistant clothes and gloves:[0.015 x {(1.155 x 0.05) + (90.86 x 0.05) + (2.49 x 0.1)} x 0.3] / 70 =(0.0728 x 0.3) / 70 = 0.0218 / 70 = 0.0003 mg/kg b.w.For 1500 m 2 – dermal exposure:With full-body chemical resistant clothes and gloves:[0.15 x {(1.155 x 0.05) + (90.86 x 0.05) + (2.49 x 0.1)} x 0.3] / 70 = (0.7275 x 0.3) / 70= 0.2182 / 70 = 0.0031 mg/kg b.w.For 2500 m 2 – dermal exposure:With full-body chemical resistant clothes and gloves:[0.25 x {(1.155 x 0.05) + (90.86 x 0.05) + (2.49 x 0.1)} x 0.3] / 70 = (1.2125 x 0.3) / 70= 0.3638 / 70 = 0.0078 mg/kg b.w.At the higher use rate of 0.3g a.i./m 2 requiring 45, 450 and 750g a.i. to be handled andapplied.For 150 m 2 – dermal exposure: With full-body chemical resistant clothes and gloves:[0.045 x {(1.155 x 0.05) + (90.86 x 0.05) + (2.49 x 0.1)} x 0.3] / 70 =(0.2182 x 0.3) / 70 = 0.0655 / 70 = 0.0009 mg/kg b.w.Inhalation exposures:For inhalation exposures from using high pressure handwand equipment indoors,APVMA modified the most relevant PHED model to account for the high volatility ofdichlorvos and estimated an inhalation exposure rate of 13.2 mg a.i./kg applied [50 foldincrease to account for the higher volatility, but also the slower volatilisation and greaterdroplet precipitation of an aerosol compared to a CO 2 pressure gun efflux].For 150 m 2 – inhalation exposure:= amount active handled [kg] x inhalation exposure [mg/kg handled]0.015 x 13.2 = 0.198 mg a.i./personDichlorvos reassessment – application Page 361 of 436