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Anti-Orexin Receptor 1 antibody (ab124199) - Abcam

Anti-Orexin Receptor 1 antibody (ab124199) - Abcam

Anti-Orexin Receptor 1 antibody (ab124199) - Abcam

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Product Datasheet<strong>Anti</strong>-<strong>Orexin</strong> <strong>Receptor</strong> 1 <strong>antibody</strong><strong>ab124199</strong>画 像 数 1OverviewProduct name<strong>Anti</strong>-<strong>Orexin</strong> <strong>Receptor</strong> 1 <strong>antibody</strong>Description Rabbit polyclonal to <strong>Orexin</strong> <strong>Receptor</strong> 1Tested applicationsSpecies reactivityImmunogenWBReacts with: HumanSynthetic peptide conjugated to KLH, corresponding to a region within internal sequence aminoacids 269-298 of Human <strong>Orexin</strong> <strong>Receptor</strong> 1 (Accessions: NP_001516.2, O43613)Positive controlPropertiesNCI-H292 cell line lysatesFormStorage instructionsStorage bufferPurityPurification notesClonalityIsotypeLiquidStore at 4°C (up to 6 months). For long term storage store at -20°CPreservative: 0.09% Sodium azideConstituent: 99% PBSImmunogen affinity purifiedPurified through a protein A column, followed by peptide affinity purification.PolyclonalIgGResearch Areas Neuroscience Neurology process Circadian Rhythm <strong>Receptor</strong>sSignal Transduction Signaling Pathway G Protein Signaling GPCRNeuroscience Neurology process MetabolismMetabolism Types of disease ObesityMetabolism Types of disease CancerApplicationsOur Abpromise guarantee covers the use of <strong>ab124199</strong> in the following tested applications.The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the enduser.ApplicationWBTargetNotesWB: 1/100 - 1/500. Predicted molecular weight: 48 kDa.FunctionSequence similaritiesCellular localizationModerately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seemsto be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase Cmediated signaling cascade.Belongs to the G-protein coupled receptor 1 family.Cell membrane.Target information above from: UniProt accession O43613 The UniProt Consortiumhttp://www.abcam.co.jp/<strong>Orexin</strong>-<strong>Receptor</strong>-1-<strong>antibody</strong>-<strong>ab124199</strong>.html 1


Product DatasheetThe Universal Protein Resource (UniProt) in 2010Nucleic Acids Res. 38:D142-D148 (2010) .Database linksAlternative namesEntrez Gene: 3061 HumanOmim: 602392 HumanSwissProt: O43613 HumanUnigene: 388226 HumanHCRTR 1 <strong>antibody</strong>HCRTR1 <strong>antibody</strong>Hypocretin receptor type 1 <strong>antibody</strong><strong>Orexin</strong> receptor type 1 <strong>antibody</strong>Ox-1-R <strong>antibody</strong>Ox1-R <strong>antibody</strong>Ox1r <strong>antibody</strong>OX1R_HUMAN <strong>antibody</strong><strong>Anti</strong>-<strong>Orexin</strong> <strong>Receptor</strong> 1 <strong>antibody</strong> images<strong>Anti</strong>-<strong>Orexin</strong> <strong>Receptor</strong> 1 <strong>antibody</strong> (<strong>ab124199</strong>)at 1/10 dilution + NCI-H292 cell line lysates at35 µgPredicted band size : 48 kDaWestern blot - <strong>Anti</strong>-<strong>Orexin</strong> <strong>Receptor</strong> 1<strong>antibody</strong> (<strong>ab124199</strong>)Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"Our Abpromise to you: Quality guaranteed and expert technical supportAs standardReplacement or refund for products not performing as stated on the datasheetValid for 12 months from date of delivery**Response to your inquiry within 24 hoursIn additionWe provide support in Chinese, English, French, German, Japanese and SpanishExtensive multi-media technical resources to help youWe investigate all quality concerns to ensure our products perform to the highest standardsIf the product does not perform as described on this datasheet, we will offer a refund or replacement. For full details of the Abpromise,please visit http://www.abcam.com/abpromise or contact our technical team.Terms and conditionsGuarantee only valid for products bought direct from <strong>Abcam</strong> or one of our authorized distributors**Regional variations to our Abpromise may apply to the following countries: China, Korea, Singapore, Malaysia, Taiwan and Thailand,which operate a 120 day guarantee. Please contact your regional office for further detailshttp://www.abcam.co.jp/<strong>Orexin</strong>-<strong>Receptor</strong>-1-<strong>antibody</strong>-<strong>ab124199</strong>.html 2


Product Datasheetwhich operate a 120 day guarantee. Please contact your regional office for further details<strong>Anti</strong>bodies tested only in recombinant samples are not covered for use on endogenous samples. Please check the datasheet forinformation on tested species"Predicted to react" information on datasheets is based on sequence homology and provided for reference only"Predicted to react" species are not guaranteed, as they have not been testedFast Track products are not covered under the Abpromise. Please see Fast Track terms and condition for additional information<strong>Abcam</strong> biochemicals are novel compounds and we have not tested their biological activity in house. Please use the literature to identifyhow to use these products effectively. If you require further assistance please contact the scientific support teamJapan Officeアブカム 株 式 会 社〒103-0012 東 京 都 中 央 区 日 本 橋 堀 留 町 2-2-1 住 友 不 動 産 人 形 町 ビル2FTel: +81-(0)3-6231-0940Fax: +81-(0)3-6231-0941Email: orders@abcam.co.jpVisit us at: www.abcam.co.jphttp://www.abcam.co.jp/<strong>Orexin</strong>-<strong>Receptor</strong>-1-<strong>antibody</strong>-<strong>ab124199</strong>.html 3

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