Assistive Reproductive Technologies: A Literature Review and ...

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n List of AcronymsAHWARTsCEACIHICMGDAMDETHOMHRQLICSIIUIIVFICERLBWNBWPGDRIWSDSETAlberta Health and Wellnessassistive reproductive technologiescost effectiveness analysisCanadian Institute for Health Informationcase mix groupdecision analytic modellingdouble embryo transferhigher order multipleshealth related quality of lifeintracytoplasmic sperm injectionintra uterine inseminationin-vitro fertilizationincremental cost effectiveness ratiolow birth weightnormal birth weightpre implantable genetic diagnosesresource intensity weightstandard deviationsingle embryo transferVIAssistive Reproductive Technologies:a Literature Review and Database Analysis
Table of ContentsAcknowledgementsExecutive SummaryList of AcronymSIIIIIvIBackground to Technology Review 1Initial Request for Technology Review 1Report Objectives 2Section 1: Review of Economic Studies 3Search Strategy 3Selection Criteria 3Quality Assessment Criteria 3Search Results 4Evidence from Published Literature 4Cost impact of ARTs on the health care system 4Costs and cost effectiveness of limiting embryo transfers 7Cost impact of providing insurance coverage or regulator policies 11Summary 13Conclusion 14Section 2: Preliminary Analyses of Available AHW Data 15Population 15Cost Data 15Statistical analyses 16Exclusion criteria for costs and visits 18Sensitivity Analysis 18Results 18Descriptive 18Regression analyses 20Logistic regression 20Linear regression 21Discussion 26Comparisons between plurality and birth weight 26Costs potentially attributable to ARTs 26Summary and Conclusion 28Caveats and Limitations of Current Evidence 29Conclusion 30References 30Assistive Reproductive Technologies:a Literature Review and Database Analysis VII
Page 1 and 2: IHE ReportAssistive ReproductiveTec
Page 3 and 4: n Assistive Reproductive Technologi
Page 5 and 6: Executive Summaryn ObjectivesThis r
Page 7: n ConclusionsBased on the evidence
Page 11 and 12: n Background to Technology ReviewAs
Page 13 and 14: Section 1: Review of Economic Studi
Page 15 and 16: naturally in 2003). Cost data was d
Page 17 and 18: vs. €13,469). The authors conclud
Page 19 and 20: IVF in Ontario are greater than the
Page 21 and 22: Cost impact of providing insurance
Page 23 and 24: the analysis had a relatively short
Page 25 and 26: Section 2: Preliminary Analyses of
Page 27 and 28: Table 2-A: Summary of statistical a
Page 29 and 30: DescriptiveThere were 36,158 mother
Page 31 and 32: Table 2-D: Probability of LBW by pl
Page 33 and 34: Figure 2-B shows the predicted hosp
Page 35 and 36: Figure 2-C: Linear prediction of in
Page 37 and 38: Figure 2-E shows the total costs an
Page 39 and 40: Caveats and Limitations of Current
Page 41 and 42: 5. Greene C, Lange I. The Assisted
Page 43 and 44: Appendix A: Search Strategyn Genera
Page 45 and 46: DatabaseWeb of ScienceISI Interface
Page 47 and 48: Data ExtractionExtracted data from
Page 49 and 50: Results Study Conclusions Evidence
Page 57 and 58: Table B-1: Hospital, physician, and
Page 59 and 60:
Trimming Outliers 2×SDInfant HospV
Page 61 and 62:
Dropped by 2*SDInfant Hosp Costs --
Page 63 and 64:
Figure B-2: Scatterplot of mother h
Page 65 and 66:
Mother Hosp Costs----Trimmed data0
Page 67 and 68:
Dropped by 2*SDInfant Hosp Costs (t
Page 69 and 70:
Figure B-4: Scatterplot of mother h
Page 71 and 72:
Dropped by 3*SDMother Hosp Costs (t
Page 73 and 74:
Infant Hosp Costs (Excluding Outlie
Page 75 and 76:
Infant Hosp Costs (Excluding Outlie
Page 77 and 78:
Infant Hosp Visits (Excluding Outli
Page 79 and 80:
Appendix E: Sensitivity Analysis Re
Page 81 and 82:
Appendix F: Calculation of Savings
Page 83 and 84:
n IHE PublicationsFor additional co
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