Assistive Reproductive Technologies: A Literature Review and ...

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Figure 2-A: Hospital and physician costs for infants$20,000$19,437Total-LBW Hosp-NBW Phys-NBWTotal-NBW Hosp-LBW Phys-LBW$18,314$18,170$17,139r Prediction of CostsLinea$15,000$10,000000$12,795$11,746$14,253$13,173$5,000$3,953$2,425$1,862$1,121$556$0Singleton$1,163Twin$3,368$1,891$657 $1,176HOMNote: Skew was assessed separately for hospital costs, physician costs and total costs. Refer to Appendix B forfurther details.Hosp: N=36,292 R-squared = 0.2294 Phys: N=36,272 R-squared =0.0993 Total: N=36,278 R-squared = 0.2245Table 2-E: Comparison of infant total costsBirth Weight Plurality Linear Predictionof Mean TotalCostCost DifferenceCompared to NBWSingletonsCost Ratio(Compared toSingletons)NBW Singleton $2425 — —NBW Twin $3953 $1528 1.63LBW Singleton $12,795 $10,370 5.28LBW Twin $14,253 $11,828 5.88NBW HOM $18,314 $15,889 7.55LBW HOM $19,437 $17,011 8.0122 Assistive Reproductive Technologies:a Literature Review and Database Analysis
Figure 2-B shows the predicted hospital and physician costs of mothers (refer toAppendix E to contrast with results when not excluding outliers). There were noHOM infants who were of LBW in the data set for mothers’ costs and thereforethe interaction between birth weight and HOMs could not be entered separatelyin the regression model. Thus, twins and HOM were grouped together and thefigure presents the predicted mean costs for singletons and ≥ twins (i.e. twinsor HOM). There were statistically significant differences (p < .05) in physician,hospital, and total costs observed between NBW and LBW infants and betweensingletons and ≥ twins (refer to Appendix D for full regression coefficients).Furthermore, there was a statistically significant interaction effect observedbetween LBW/NBW singletons and LBW/NBW ≥ twins for hospital andtotal costs.Mothers of NBW singletons were associated with the lowest mean total cost($4695), followed by mothers of LBW singletons ($5733), mothers of NBW ≥twins ($6707), and mothers of LBW ≥ twins ($7216) (see Table 2-F). Comparedto mothers of NBW singletons, total costs were 1.22 times greater for mothers ofLBW singletons ($1039 more), 1.43 times greater for mothers of NBW ≥ twins($2012 greater) and 1.54 times greater for mothers of LBW ≥ twins($2521 greater).Figure 2-B: Hospital and physician costs for mothersHosp-NBW Hosp-LBW Phys-NBWPhys-LBW Total-NBW Total-LBW$7,216$6,707(Mother Costs)Linear Prediction$5,733$4,695$3,701$2,733$2,405$2,072$4,780$4,105$3,544$3,1361000SingletonTwin plus HOMNote: Skew was assessed separately for hospital costs, physician costs and total costs. Refer to Appendix B for furtherdetails. There were no HOM infants who were of LBW in the data set for mother’s costs and therefore HOM could notbe entered separately in the regression model. Therefore the figure presents the linear prediction of costs of singletonsand ≥twins.Hosp: N=35,261 R-squared =0.0371; Phys: N=36,158 R-squared = 0.0249; Total: N=34,787 R-squared = 0.0276Assistive Reproductive Technologies:a Literature Review and Database Analysis 23
Page 1 and 2: IHE ReportAssistive ReproductiveTec
Page 3 and 4: n Assistive Reproductive Technologi
Page 5 and 6: Executive Summaryn ObjectivesThis r
Page 7 and 8: n ConclusionsBased on the evidence
Page 9 and 10: Table of ContentsAcknowledgementsEx
Page 11 and 12: n Background to Technology ReviewAs
Page 13 and 14: Section 1: Review of Economic Studi
Page 15 and 16: naturally in 2003). Cost data was d
Page 17 and 18: vs. €13,469). The authors conclud
Page 19 and 20: IVF in Ontario are greater than the
Page 21 and 22: Cost impact of providing insurance
Page 23 and 24: the analysis had a relatively short
Page 25 and 26: Section 2: Preliminary Analyses of
Page 27 and 28: Table 2-A: Summary of statistical a
Page 29 and 30: DescriptiveThere were 36,158 mother
Page 31: Table 2-D: Probability of LBW by pl
Page 35 and 36: Figure 2-C: Linear prediction of in
Page 37 and 38: Figure 2-E shows the total costs an
Page 39 and 40: Caveats and Limitations of Current
Page 41 and 42: 5. Greene C, Lange I. The Assisted
Page 43 and 44: Appendix A: Search Strategyn Genera
Page 45 and 46: DatabaseWeb of ScienceISI Interface
Page 47 and 48: Data ExtractionExtracted data from
Page 49 and 50: Results Study Conclusions Evidence
Page 57 and 58: Table B-1: Hospital, physician, and
Page 59 and 60: Trimming Outliers 2×SDInfant HospV
Page 61 and 62: Dropped by 2*SDInfant Hosp Costs --
Page 63 and 64: Figure B-2: Scatterplot of mother h
Page 65 and 66: Mother Hosp Costs----Trimmed data0
Page 67 and 68: Dropped by 2*SDInfant Hosp Costs (t
Page 69 and 70: Figure B-4: Scatterplot of mother h
Page 71 and 72: Dropped by 3*SDMother Hosp Costs (t
Page 73 and 74: Infant Hosp Costs (Excluding Outlie
Page 75 and 76: Infant Hosp Costs (Excluding Outlie
Page 77 and 78: Infant Hosp Visits (Excluding Outli
Page 79 and 80: Appendix E: Sensitivity Analysis Re
Page 81 and 82: Appendix F: Calculation of Savings
Page 83 and 84:
n IHE PublicationsFor additional co
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