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Das B.P. et al. 111 have found that chalcones possesses larvicidal properties.Kim Min-Young et al. 112 have synthesized chalcones and tested for their matrixmetalloproteinase inhibitor activity. Satyanarayana M. et al. 113 have synthesisedchalcone derivatives as antihyperglycemic activity (Type-II)CH 2R"C H 3NO .C H 3HOType-IIMoreover, synthesis and antibacterial activity of substituted chalconederivatives have been reported by Modi et al. 114 and Attia A. 115 , V. Mudalir et al. 116have prepared phenoxy chalcones and observed their insecticidal activity, Kammeiet al. 117 have synthesised chalcone derivatives having antitumor activity.De Vincenzo et al. 118 and Han et al. 119 have reported chalcone derivatives for theirantiinflammatory activity.Aldose reductanse inhibitor activity of chalcone derivatives have beenreported by Okuyama et al. 120 Chalcones are also associated with antitumor andantifungal activity as reported by A. Tsotitns and co-worker. 121 Antifeedant activity ofchalcones have been observed by Sarma and Sreenivasulu. 122 Liu Mei et al. 123 haveprepared antimalarial chalcones. Opletalova Veronika et al. 124 have synthesisedchalcones and screened as cardiovascular agents. Moreover, it has been found thatchalcone derivatives possesses nitric oxide inhibitor 125,126 anti HIV 127,128 andantiproliferative 129,130 activities.26Chalcone…..