10th Symposium on the Flora of Southeastern Serbia and ...
10th Symposium on the Flora of Southeastern Serbia and ...
10th Symposium on the Flora of Southeastern Serbia and ...
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10 th <str<strong>on</strong>g>Symposium</str<strong>on</strong>g> <strong>on</strong> <strong>the</strong> <strong>Flora</strong> <strong>of</strong> Sou<strong>the</strong>astern <strong>Serbia</strong> <strong>and</strong> Neighbouring regi<strong>on</strong>s,Vlasina 17 to 20 June 2010Percentage proporti<strong>on</strong> <strong>of</strong> camphor in leaves <strong>of</strong> <strong>the</strong>se plants may be significantchemosystematic delineati<strong>on</strong>.Health properties <strong>of</strong> extracts <strong>of</strong> two wild garlic taxa(Alliumvineale, Alliaceae)Bozin, B. 1 , Lakic, N. 1 , Samojlik, I. 2 , Mimica-Dukic, N 3 , Igic, R. 4 , Anackov,G. 41 Medicinski fakultet, Katedra za farmaciju, Novi Sad, Srbija2 Department <strong>of</strong> Pharmacology <strong>and</strong> Toxicology, Faculty <strong>of</strong> Medicine, HajdukVeljkova 3, University <strong>of</strong> Novi Sad, 21000 Novi Sad, <strong>Serbia</strong>3 Department <strong>of</strong> Chemistry, Faculty <strong>of</strong> Sciences, Trg D. Obradovica 3University <strong>of</strong> Novi Sad, 21 000 Novi Sad, <strong>Serbia</strong>4 University <strong>of</strong> Novi Sad, Faculty <strong>of</strong> Sciences, Department <strong>of</strong> Biology <strong>and</strong>Ecology, <strong>Serbia</strong>nedalakic@yahoo.comAlthough <strong>the</strong> health benefits <strong>of</strong> different garlic preparati<strong>on</strong>s (Allium sativum,Alliaceae) are well documented, <strong>the</strong>re is very few data <strong>on</strong> chemistry <strong>and</strong> healthpropreties <strong>of</strong> different taxa <strong>of</strong> wild garlic, A. vineale. With respect to this, in <strong>the</strong>present study wide array <strong>of</strong> biological <strong>and</strong> pharmacological properties <strong>of</strong> twovarieties <strong>of</strong> A. vineale (A. vineale subsp. vineale <strong>and</strong> A. vineale subsp. compactum)comparing to A. sativum extracts are presented. Antioxidant activity was evaluatedas free radical-scavenging capacity (RSC), toge<strong>the</strong>r with <strong>the</strong> effect <strong>on</strong> lipidperoxidati<strong>on</strong> (LP). RSC was assessed by measuring <strong>the</strong> scavenging activity <strong>of</strong> garlicextracts <strong>on</strong> 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical <strong>and</strong> hydrogen peroxide.Effects <strong>on</strong> LP were evaluated by following <strong>the</strong> activities <strong>of</strong> examined garlic extractsin Fe2+/ascorbate <strong>and</strong> Fe2+/H2O2 systems <strong>of</strong> inducti<strong>on</strong>. Antimicrobial activity wastested against several bacterial strains <strong>and</strong> fungi. Fur<strong>the</strong>rmore, <strong>the</strong> influence <strong>of</strong> examined extracts <strong>on</strong> gut micr<strong>of</strong>lora was evaluated. Fur<strong>the</strong>rmore, <strong>the</strong> effects <strong>of</strong> <strong>the</strong>extracts <strong>on</strong> different liver enzymes after intoxicati<strong>on</strong> with carb<strong>on</strong> tetrachloride wereassayed. In all <strong>of</strong> <strong>the</strong> examined model systems extrats <strong>of</strong> A. vineale exhibitedstr<strong>on</strong>ger antioxidant effects comparing to garlic. Similar results were obtained forantimicrobial activities <strong>and</strong> effects <strong>on</strong> gut micr<strong>of</strong>lora. In vivo investigati<strong>on</strong> pointed<strong>on</strong> similar protective activity <strong>of</strong> both investigated species.95
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