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incorporating the BES1-5 April 2006Scottish Exhibition and Conference CentreGLASGOW, UKProgrammewww.ece2006.com
8th European Congressof <strong>Endocrinology</strong>incorporating the BES1-5 April 2006Scottish Exhibition and Conference CentreGLASGOW, UKECE 2006 Secretariat<strong>Society</strong> <strong>for</strong> <strong>Endocrinology</strong>22 Apex CourtWoodlandsBradley StokeBristol BS32 4JTUKContact: Liz BrookesTel: +44 (0)1454 642210Fax: +44 (0)1454 642222Email: conferences@endocrinology.orgWeb: www.ece2006.comThe <strong>Society</strong> <strong>for</strong> <strong>Endocrinology</strong>Company Limited by GuaranteeRegistered in England No 349408Registered office as shown aboveRegistered Charity No 26618www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>ContentsCongress in<strong>for</strong>mation 4Accreditation, Badges, Business meetings,Cloakroom, Commercial exhibition, Disabledvisitors, Disclaimer, Glasgow, Internet access,Language, Meals and refreshments, Media,Messages, Posters, Programme changes,Registration on-site in Glasgow, Slide preview room,Transport links, VenueProgramme OrganisingCommittee:Pierre Bouloux, UK (Chair)Josef Köhrle, Germany (Chair)Maria Alevizaki, GreecePaolo Beck-Peccoz, ItalyFrank Claessens, BelgiumKevin Docherty, UKWouter de Herder, The NetherlandsIlpo Huhtaniemi, UKChris Kelnar, UKEwa Malecka-Tendera, PolandChristoph Meier, SwitzerlandPeter Selby, UKMike Sheppard, UKBrian Walker, UKLocal Organising Committee:John Connell, Glasgow (Chair)Graham Beastall, GlasgowJohn Bevan, AberdeenPierre Bouloux, LondonNick Finer, CambridgeAshley Grossman, LondonColin Perry, GlasgowMartin Savage, LondonPeter Selby, ManchesterPeter Trainer, ManchesterPrize lectures and awards 5Social events 6Satellite sessions 7Overview programme 9Programme 15Saturday 1 April 15Sunday 2 April 15Monday 3 April 19Tuesday 4 April 22Wednesday 5 April 25Attended posters 29Floor plan 73Sponsors and exhibitors 74General UK in<strong>for</strong>mation 80Banking, Bureaux de change, Credit cards, Currency, Customs,Electricity, Embassies and consulates, Emergency services, Healthcare, Smoking, Telephone, Time, Tipping, Travel insurance,Vaccinations, Value-added tax (VAT),VisasTimetableinside back coverEuropean <strong>Society</strong> of <strong>Endocrinology</strong>(ESE) Executive CommitteeFor details please see the ESE web siteat www.euro-endo.org.ECE Abstract MarkersThe Programme Organising Committeewishes to thank all the abstract markers,who marked all the submissions <strong>for</strong> <strong>ECE2006</strong> in their own time.2www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>Congress In<strong>for</strong>mationPrize Lectures and AwardsProgramme changesThe organisers cannot assume liability <strong>for</strong> any changes inthe programme due to external or un<strong>for</strong>eseencircumstances.Registration on-site in GlasgowOn-site registration will start on Saturday 1 April at12.00 in Hall 3. The registration desk will be open at thefollowing times:Saturday 1 April 12.00-18.30Sunday 2-Tuesday 4 April 07.00-18.30Wednesday 5 April 07.00-16.00Slide preview roomThe Gala room will be the slide preview room andspeakers' lounge. This room will be available <strong>for</strong> speakersthroughout the congress. Speakers will be directed tothis room to drop off their presentations. Please note youwill not be able to use your own laptop <strong>for</strong> yourpresentation.Transport linksGlasgow has an excellent public transport network. TheSECC is served by a low-level train from Glasgow CentralStation, with a 5-minute journey time. Visitwww.spt.co.uk <strong>for</strong> local travel in<strong>for</strong>mation.Further in<strong>for</strong>mation regarding travel to Glasgow andfrom the airport can be found on our web site atwww.ece2006.com.VenueScottish Exhibition and Conference Centre, Glasgow G38YW, UK (Tel: +44 (0)141 2483000; Fax: +44 (0)1412263423; Email: info@secc.co.uk).The SECC is one of the world's finest conference venues.All sessions will be held within one compact site, withfirst-rate auditoria, meeting rooms and exhibition space.Geoffrey Harris PrizeThis prestigious prize is intended <strong>for</strong> established workersin the field of basic or clinical neuroendocrinology, and isgenerously supported by Ipsen Ltd. The winner of the2006 prize, Felipe Casanueva (Santiago de Compostela,Spain), will deliver a lecture at ECE 2006 from 17.30 to18.15 on Saturday 1 April in the Clyde Auditorium.European Journal of <strong>Endocrinology</strong> PrizeThis prize is awarded to a candidate who has significantlycontributed to the advancement of knowledge inendocrinology through publication. The recipient of thisprize, Sabine Costagliola (Brussels, Belgium) will give alecture at ECE 2006 from 16.30 to 17.15 on Saturday 1April in the Clyde Auditorium, and will also write areview paper to be published in European Journal of<strong>Endocrinology</strong>.Novartis Oncology Young Investigator AwardsSix European <strong>Society</strong> of <strong>Endocrinology</strong> (ESE) YoungInvestigator Awards of €3000, generously sponsored byNovartis Pharmaceuticals, will be presented toresearchers who have submitted abstracts (basic orclinical) to ECE 2006. Recipients are the first andpresenting authors of the abstracts, and will be less than35 years of age at the time of the meeting. The awardsare based on the achieved abstract scores, as determinedby the ECE Abstract Review Committee. The finaldecision has been made by the ECE ProgrammeOrganising Committee. Successful applicants will presenttheir abstracts as oral communications during theprogramme and will be presented with their awardcertificates during the closing ceremony.The six ESE Young Investigator Award recipients <strong>for</strong> 2006are as follows:Dr C Eller-Vainicher (Milan, Italy) <strong>for</strong> OC49Dr SR James (Birmingham, UK) <strong>for</strong> OC62Dr E Karteris (Coventry, UK) <strong>for</strong> OC10Mrs D Markovic (Coventry, UK) <strong>for</strong> OC2Dr E Murphy (London, UK) <strong>for</strong> OC51Mr AV Patchev (Berlin, Germany) <strong>for</strong> OC1These are marked in the programme book with anasterix.British Thyroid Association AwardThe BES and the British Thyroid Association are awardinga prize of £500 to the young researcher at the ECE 2006meeting who submits the highest scoring abstract in thethyroid field. Abstracts eligible <strong>for</strong> the award weresubmitted under the thyroid category, with a first authorunder the age of 35.The 2006 recipient is Dr JA Gilbert (London, UK).The abstract will be presented as part of OralCommunications 8 on Wednesday 5 April at 13.35 in theForth Room. The prize will be awarded on Wednesday 5April at 15.35 during the closing ceremony.www.ece2006.com 5CONGRESS INFORMATION / PRIZE LECTURES AND AW ARDS
8th European Congress of <strong>Endocrinology</strong>Social EventsGolf TournamentSATURDAY 1 APRIL 2006A golf tournament will be held at Glasgow Golf Club andis open to everyone who indicated their interest on theregistration <strong>for</strong>m. If you require any further in<strong>for</strong>mationplease contact Colin Perry (Tel: +44 (0)141 2112108;Email: colin@fulcrum.u-net.com).Five-a-side Football TournamentSATURDAY 1 APRIL 2006A five-a-side football tournament is taking place atDrumchapel, Great Western Road, Glasgow and is opento everyone who indicated their interest on theregistration <strong>for</strong>m. If you require further in<strong>for</strong>mationplease contact Colin Perry (Tel: +44 (0)141 2112108;Email: colin@fulcrum.u-net.com).Congress Banquet and CeilidhTUESDAY 4 APRIL 2006, 19.30,HILTON HOTEL, GLASGOW(Tickets €90/£65 each; sold on a first-come first-served basis)Mention 'Scotland' and 'dance' in the same breath and,<strong>for</strong> many, you'll immediately conjure up mental picturesof swinging kilts, the 'Highland Fling' and even crossedswords (danced over on the floor, that is!). But thesearen't just clichés: dance has always had an importantplace at all levels of Scottish society and, even today, it isstill very much a living tradition. So why not join yourfellow delegates in some exuberant dancing at theceilidh? This will follow the three-course gala dinner,served with wine, and Diagoe's will also kindly provide anafter dinner drink. (See www.hilton.co.uk/glasgow.)SOCIAL EVENTS6Tennis TournamentSATURDAY 1 APRIL 2006A tennis tournament will be held at the Scotstoun LeisureCentre and is open to everyone who indicated theirinterest on the registration <strong>for</strong>m. If you require anyfurther in<strong>for</strong>mation please contact Maggie Carson (Tel:+44 (0)131 2421378; Email: m.n.carson@ed.ac.uk).Welcome ReceptionSATURDAY 1 APRIL 2006, 18.30-20.00,GLASGOW SCIENCE CENTREJoin your colleagues <strong>for</strong> this welcome reception atGlasgow Science Centre and follow the piper from theauditorium to the venue. An example of contemporaryexcellence in a unique setting, Glasgow Science Centre isa £75m collection of attractions to illuminate, intrigue,inspire and fire your imagination. The welcome receptiongives delegates an opportunity to network with oneanother after the first day of sessions. Glasgow's LordProvost will welcome you to the city over a glass ofsomething bubbly! (See www.glasgowsciencecentre.org.)The Sunday SocialSUNDAY 2 APRIL 2006, 19.00,TIGER TIGER, GLASGOW(Tickets €15/£11 each)For those of you wishing to enjoy a relaxed evening withcolleagues, enjoying a drink and maybe a dance, whynot buy a ticket <strong>for</strong> the social event at Tiger Tiger?Set over several floors, the contemporary restaurant,laid-back lounge, funky Kaz bar and upbeat club eachhave their own distinct style, décor and soundtrack.Ticket price includes a complimentary drink and fingerbuffet. Please show ticket to gain entry. (Seewww.tigertiger-glasgow.co.uk.)www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>Satellite SessionsNovartis PharmaceuticalsSUNDAY 2 APRIL 12.20-13.50FORTH ROOMFrom controversy to clarity inacromegaly managementChair: M Sheppard (Birmingham, UK)Acromegaly is a clinical condition in which there is still avigorous debate as to optimal management options andoutcomes. This satellite symposium distils the conflictingscience and delivers practical treatment guidance.Professor Michael Sheppard (Birmingham, UK) will chairthe meeting and will conclude with an overview of theissues raised and a summary of practical advice ontreatment strategies <strong>for</strong> the clinical endocrinologist.Does surgery enhance the role of somatostatinanalogues or do somatostatin analogues enhance therole of surgery?R Cozzi (Milan, Italy)Medical therapy as primary therapy – how successfulis it?M Reincke (Munich, Germany)Target objectives – practical markers or academic debate?S Webb (Barcelona, Spain)Controversies or consensus?M Sheppard (Birmingham, UK)IpsenSUNDAY 2 APRIL 18.30-20.00CLYDE AUDITORIUMTailoring therapies <strong>for</strong> patients withendocrine disordersChairs: S Lamberts (Rotterdam, The Netherlands) &M Sheppard (Birmingham, UK)Self administration and longer injection intervalwith AutogelJ Bevan (Aberdeen, UK)Cardiac safety of SST analogs <strong>for</strong> acromegaly treatment:new data comparing Lanreotide to OctreotideG Lombardi (Naples, Italy)Choice of testosterone preparation <strong>for</strong> substitutiontherapyE Nieschlag (Münster, Germany)Transition from child to adult therapyW Drake (London, UK)Shire PharmaceuticalsMONDAY 3 APRIL 12.20-13.50PCOS - the cruel face of a complex diseaseChair: S Atkin (Hull, UK)The symposium will investigate the dermatologicalmanifestations with which PCOS patients present.FORTH ROOMUnderstanding the underlying pathophysiology has ledto an increased number of successful treatmentregimens.The complex collection of symptoms that make up PCOSwill be discussed by our next speaker especially in relationto adolescents. How we diagnose, treat and manage thisparticular group of patients will also be addressed.Canapes will be served prior to the commencement ofthe symposia.Pfizer 1MONDAY 3 APRIL 12.20-13.50CLYDE AUDITORIUMYoung, middle-aged and elderly patients withGH deficiency: insights into age-related responsesto GH replacementChair: J Sandahl Christiansen (Aarhus, Denmark)More than 10 years of experience in GH replacementhas guided us to understand individual needs of adultpatients with GH deficiency, not only in terms of doseadjustment, but also the ways they benefit most fromtreatment. The picture that emerges indicates differentage-related patterns of treatment response. This sessionwill provide insights that may help endocrinologistsexpect different responses and benefits depending onthe individual patient's phase of life.The transition: reaching full somatic developmentP Clayton (Manchester, UK)The middle-aged: securing cardiovascular healthJ Monson (London, UK)The third age: restoration of normality and abilityto enjoy itS Shalet (Manchester, UK)Pfizer 2MONDAY 3 APRIL 18.30-20.00CLYDE AUDITORIUMClinical management of acromegaly: applying10 years of human experience with pegvisomantChair: E Ghigo (Turin, Italy)It has now been 10 years since the first human studies withpegvisomant began. Initial safety and efficacy findingscontinue to be borne out in its use as a single medicaltherapy with unique benefits in the treatment of acromegaly.Acrostudy: learnings from the pegvisomantsurveillance programC Strasburger (Berlin, Germany)The importance of dose titration in normalisingIGF-I levelsP Trainer (Manchester, UK)Pegvisomant actions and glucose homeostasisD Dunger (Cambridge, UK)www.ece2006.com 7SATELLITE SESSIONS
8th European Congress of <strong>Endocrinology</strong>Overview ProgrammeSaturday 1 April 2006From 12.00RegistrationHALL 316.15-16.30 Opening CeremonyCLYDE AUDITORIUM16.30-17.15 European Journal of <strong>Endocrinology</strong>Prize LectureCLYDE AUDITORIUM17.30-18.15 Geoffrey Harris Prize LectureCLYDE AUDITORIUM18.30-20.00 Welcome ReceptionGLASGOW SCIENCE CENTREOVERVIEW PROGRAMMEwww.ece2006.com 9
8th European Congress of <strong>Endocrinology</strong>Sunday 2 April 200607.15-08.00 Meet the Expert 1:MacroprolactinaemiaCLYDE AUDITORIUM07.15-08.00 Meet the Expert 2:Gestational diabetesLOMOND AUDITORIUM07.15-08.00 Meet the Expert 3:Chips, arrays and biosensors:bioin<strong>for</strong>matics in endocrineresearchHALL 107.15-08.00 Meet the Expert 4:Cell immortalisation inendocrine researchFORTH ROOM08.10-10.10 Symposium 1:Thyroid and the heartCLYDE AUDITORIUM08.10-10.10 Symposium 2:The endocrinology ofpsychiatric diseaseLOMOND AUDITORIUM08.10-10.10 Clinical Management Workshop 1:Green over-the-counterendocrinologyHALL 108.10-10.10 Oral Communications 1:Signal transductionALSH ROOM08.10-10.10 Young Endocrinologists Session:Presenting your research -getting your work knownFORTH ROOM10.10-10.40 COFFEEHALL 311.35-12.20 Meet the Expert 4:Cell immortalisation inendocrine researchFORTH ROOM12.20-13.50 Novartis PharmaceuticalsSatellite SymposiumFrom controversy to clarity inacromegaly managementFORTH ROOM13.50-14.50 POSTERS AND LUNCHHALL 314.50-16.50 Symposium 3:Cancer and the skeletonCLYDE AUDITORIUM14.50-16.50 Symposium 4:Cannabinoid signallingLOMOND AUDITORIUM14.50-16.50 Clinical Management Workshop 2:Management of complex genitalanomalies and the transition fromchildhood to adulthoodFORTH ROOM14.50-16.50 Oral Communications 2:Steroids and reproductiveendocrinologyHALL 116.50-17.30 TEAHALL 317.30-18.15 Plenary 1:Vitamin D actionCLYDE AUDITORIUM18.30-20.00 Ipsen Satellite SymposiumTailoring therapies <strong>for</strong> patientswith endocrine disordersCLYDE AUDITORIUM10.40-11.25 <strong>Society</strong> <strong>for</strong> <strong>Endocrinology</strong>Transatlantic Medal LectureCLYDE AUDITORIUMFrom 19.00The Sunday SocialTIGER TIGEROVERVIEW PROGRAMME11.35-12.20 Meet the Expert 1:MacroprolactinaemiaCLYDE AUDITORIUM11.35-12.20 Meet the Expert 2:Gestational diabetesLOMOND AUDITORIUM11.35-12.20 Meet the Expert 3:Chips, arrays and biosensors:bioin<strong>for</strong>matics in endocrineresearchHALL 110www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>Monday 3 April 200607.15-08.00 Meet the Expert 5:Papillary thyroid cancermanagementCLYDE AUDITORIUM07.15-08.00 Meet the Expert 6:Adrenal carcinomaLOMOND AUDITORIUM07.15-08.00 Meet the Expert 7:Transgenic techniquesHALL 107.15-08.00 Meet the Expert 8:Pitfalls in signal transductionresearchFORTH ROOM08.10-10.10 Symposium 5:Novel peptides in reproductionCLYDE AUDITORIUM08.10-10.10 Oral Communications 3:Clinical endocrinologyHALL 108.10-10.10 Symposium 6:Hot topicsLOMOND AUDITORIUM08.10-10.10 Symposium 7:Flies, worms and fish:use in endocrine researchFORTH ROOM10.10-10.40 COFFEEHALL 310.40-11.25 Clinical <strong>Endocrinology</strong> TrustVisiting Professor LectureCLYDE AUDITORIUM11.35-12.20 Meet the Expert 5:Papillary thyroid cancermanagementCLYDE AUDITORIUM11.35-12.20 Meet the Expert 6:Adrenal carcinomaLOMOND AUDITORIUM11.35-12.20 Meet the Expert 7:Transgenic techniquesHALL 111.35-12.20 Meet the Expert 8:Pitfalls in signal transductionresearchFORTH ROOM12.20-13.50 Shire PharmaceuticalsSatellite SymposiumPCOS - the cruel face ofa complex diseaseFORTH ROOM12.20-13.50 Pfizer Satellite Symposium 1Young, middle-aged and elderlypatients with GH deficiency:insights into age-related responsesto GH replacementCLYDE AUDITORIUM13.50-14.00 <strong>Society</strong> <strong>for</strong> <strong>Endocrinology</strong> EGMCLYDE AUDITORIUM14.00-14.45 British Thyroid Association AGMALSH ROOM13.50-14.50 POSTERS AND LUNCHHALL 314.50-16.50 Symposium 8:Clinical lessons from novel aspectsof G protein-coupled receptorssignallingCLYDE AUDITORIUM14.50-16.50 Clinical Management Workshop 3:Management of Graves'ophthalmopathyLOMOND AUDITORIUM14.50-16.50 Basic Science Workshop:In vivo imaging of signallingHALL 114.50-16.50 Oral Communications 4:Diabetes and metabolism16.50-17.30 TEAFORTH ROOMHALL 317.30-18.15 Plenary 2:Statins and rhabdomyolysisCLYDE AUDITORIUM18.30-20.00 Pfizer Satellite Symposium 2Clinical management ofacromegaly: applying 10 yearsof human experience withpegvisomantCLYDE AUDITORIUMFREE EVENINGOVERVIEW PROGRAMMEwww.ece2006.com 11
8th European Congress of <strong>Endocrinology</strong>Tuesday 4 April 200607.15-08.00 Meet the Expert 9:Medical management ofCushing's diseaseCLYDE AUDITORIUM07.15-08.00 Meet the Expert 10:Graves' ophthalmopathyLOMOND AUDITORIUM07.15-08.00 Meet the Expert 11:Metabolic, functional andoncological consequences ofaltered GH/IGF expressionHALL 107.15-08.00 Meet the Expert 12:Growth hormone deficiencyin adultsFORTH ROOM08.10-10.10 Symposium 9:Stromal cell-matrix interactionsLOMOND AUDITORIUM08.10-10.10 Symposium 10:Controversies in male healthCLYDE AUDITORIUM08.10-10.10 Oral Communications 5:Neuroendocrinology and neoplasiaFORTH ROOM08.10-10.10 Nurses Session:Metabolic syndromeALSH ROOM10.10-10.40 COFFEEHALL 310.40-11.25 British Thyroid AssociationPitt-Rivers LectureCLYDE AUDITORIUM11.35-12.20 Meet the Expert 9:Medical management ofCushing's diseaseCLYDE AUDITORIUM11.35-12.20 Meet the Expert 10:Graves' ophthalmopathyLOMOND AUDITORIUM11.35-12.20 Meet the Expert 11:Metabolic, functional andoncological consequences ofaltered GH/IGF expressionHALL 111.35-12.20 Meet the Expert 12:Growth hormone deficiencyin adultsFORTH ROOM12.20-13.50 European <strong>Society</strong> of <strong>Endocrinology</strong>AGMCLYDE AUDITORIUMfollowed by a drinks reception <strong>for</strong> attendees inthe Gala Foyer13.50-14.50 POSTERS AND LUNCHHALL 314.50-16.50 Symposium 11:How hormones get into cellsCLYDE AUDITORIUM14.50-16.50 Symposium 12:<strong>Endocrinology</strong> in the fetusHALL 114.50-16.50 Clinical Management Workshop 4:Contrasting practices inEuropean endocrinologyLOMOND AUDITORIUM14.50-16.50 Oral Communications 6:Endocrine geneticsFORTH ROOM16.50-17.30 TEAHALL 317.30-18.15 <strong>Society</strong> <strong>for</strong> <strong>Endocrinology</strong>Dale Medal LectureCLYDE AUDITORIUMFrom 19.30Congress Banquet and CeilidhHILTON HOTELOVERVIEW PROGRAMMEwww.ece2006.com 13
8th European Congress of <strong>Endocrinology</strong>Wednesday 5 April 200607.15-08.00 Meet the Expert 13:Pregnancy-related pituitarydisordersCLYDE AUDITORIUM07.15-08.00 Meet the Expert 14:Hypoglycaemia and insulinomaLOMOND AUDITORIUM07.15-08.00 Meet the Expert 15:Interference in hormone assaysHALL 107.15-08.00 Meet the Expert 16:Mouse genetics in the identificationof quantitative traitsFORTH ROOM08.10-10.10 Symposium 13:Monogenic disorders illuminatemetabolic diseaseCLYDE AUDITORIUM08.10-10.10 Symposium 14:Steroid hormone receptorsHALL 108.10-10.10 Symposium 15:Anabolic hormones in sportLOMOND AUDITORIUM08.10-10.10 Oral Communications 7:Calcium and boneFORTH ROOM10.10-10.40 COFFEEHALL 310.40-11.25 Clinical <strong>Endocrinology</strong> Trust LectureCLYDE AUDITORIUM11.35-12.20 Plenary 3:Stem cells: regenerationin type 1 diabetesLOMOND AUDITORIUM12.20-13.05 Meet the Expert 13:Pregnancy-related pituitarydisordersCLYDE AUDITORIUM12.20-13.05 Meet the Expert 14:Hypoglycaemia and insulinomaLOMOND AUDITORIUM12.20-13.05 Meet the Expert 15:Interference in hormone assaysHALL 112.20-13.05 Meet the Expert 16:Mouse genetics in the identificationof quantitative traitsFORTH ROOM13.05-13.35 LUNCHHALL 313.35-15.35 Symposium 16:Disorders of melanocortin receptorfunctionsLOMOND AUDITORIUM13.35-15.35 Symposium 17:Endocrine oncogenesis andmanagement of hereditaryendocrine tumoursCLYDE AUDITORIUM13.35-15.35 Clinical Management Workshop 5:Research management workshopHALL 113.35-15.35 Oral Communications 8:ThyroidFORTH ROOM15.35 Novartis Oncology Young InvestigatorAward and BTA Award Announcementsand Close of MeetingCLYDE AUDITORIUMOVERVIEW PROGRAMME11.35-12.20 Debate:Met<strong>for</strong>min is the treatment ofchoice <strong>for</strong> polycystic ovariansyndromeCLYDE AUDITORIUM14www.ece2006.com
ProgrammeSaturday 1 April 2006 Sunday 2 April 20068th European Congress of <strong>Endocrinology</strong>From 12.00RegistrationHALL 316.15-16.30 Opening CeremonyCLYDE AUDITORIUMJ Wass (Ox<strong>for</strong>d, UK)16.30-17.15 European Journal of <strong>Endocrinology</strong>Prize LectureS1CLYDE AUDITORIUMChair: P Beck Peccoz (Milan, Italy)Evolutionary mechanisms of glycoproteinhormone receptors (TSHr, LH/CGr andFSHr) to cope with hCG in humansS Costagliola (Brussels, Belgium)17.30-18.15 Geoffrey Harris Prize LectureGENEROUSLY SUPPORTED BY IPSEN LTDS2CLYDE AUDITORIUMChair: S Lamberts(Rotterdam, The Netherlands)Ghrelin: a tale of modern endocrinologyF Casanueva(Santiago de Compostela, Spain)18.30-20.00 Welcome ReceptionGLASGOW SCIENCE CENTRE07.15-08.00 Meet the Expert 1:MacroprolactinaemiaCLYDE AUDITORIUMChair: TBAP Chanson (Paris, France)07.15-08.00 Meet the Expert 2:Gestational diabetesLOMOND AUDITORIUMChair: D Johnston (London, UK)R Corcoy (Barcelona, Spain)07.15-08.00 Meet the Expert 3:Chips, arrays and biosensors:bioin<strong>for</strong>matics in endocrineresearchHALL 1Chair: V Pirags (Riga, Latvia)A Turner (Leicester, UK)07.15-08.00 Meet the Expert 4:Cell immortalisation in endocrineresearchFORTH ROOMChair: TBAS Kim (London, UK)08.10-10.10 Symposium 1:Thyroid and the heartCLYDE AUDITORIUMChairs: A Tsatsoulis (Ioannina, Greece) &J Franklyn (Birmingham, UK)S11 08.10 Cardiac repercussions of thyroidhormonesJ Franklyn (Birmingham, UK)S12 08.40 The assessment of cardiovascular riskfactors in thyroid diseaseB Biondi (Naples, Italy)S13 09.10 Iodothyronamines: rapid-acting thyroidhormone metabolitesT Scanlan (San Francisco, USA)S14 09.40 Role of thyroid hormone receptoriso<strong>for</strong>ms in development and function ofheart and other tissuesJ Samarut (Lyon, France)08.10-10.10 Symposium 2:The endocrinology of psychiatricdiseaseLOMOND AUDITORIUMChair: P Bouloux (London, UK)S15 08.10 Glucocorticoids, enzymes and memoryimpairments with ageingJ Seckl (Edinburgh, UK)PROGRAMMEwww.ece2006.com 15
8th European Congress of <strong>Endocrinology</strong>PROGRAMME16Sunday 2 April 2006 - continuedS16 08.40 Effects of hypothyroidism on brainmetabolism and its associations withneuropsychiatric impairmentsM Bauer (Berlin, Germany)S17 09.10 Overview of neuroendocrine side-effectsR Tandon (Ann Arbor, USA)S18 09.40 <strong>Endocrinology</strong> of post-traumatic stressC Kirshbaum (Dresden, Germany)08.10-10.10 Clinical Management Workshop 1:Green over-the-counterendocrinologyHALL 1Chair: R Sharpe (Edinburgh, UK)S75 08.10 Regulation of steroid receptor expressionand proliferation in prostate cancer bygenistein and other flavonoidsH Klocker (Innsbruck, Austria)S76 08.40 Soy, flavonoids and osteoporosisE Lydeking-Olsen (Copenhagen, Denmark)S77 09.10 Aftermath of WHI: the risks or benefits ofred clover and soy extracts inpostmenopausal OTC HRTW Wuttke (Göttingen, Germany)08.10-10.10 Oral Communications 1:Signal transductionOC1* 08.10OC2* 08.25ALSH ROOMChairs: M Tena Sempere (Cordoba, Spain) &W Knepel (Göttingen, Germany)Stress response after TIF-2 disruption: lossof grip on feedback control oradrenocortical impairment?AV Patchev, D Fischer, M Herkenham, F Götz,SS Wolf, M Gehin, P Chambon, VK Patchev &OFX AlmeidaSignalling and internalisationcharacteristics of corticotropin-releasinghormone (CRH) receptorsD Markovic & D GrammatopoulosOC3 08.40 Activation of cyclic AMP (cAMP) bindingprotein (CREB) by gonadotrophinreleasinghormone (GnRH) requirescalcium influx and PKC activity ingonadotroph cell linesKC Jonas, IA Thompson, JM Burrin & RC FowkesOC4 08.55 The role of MRAP in the functionalexpression of the melanocortin 2receptorSN Cooray, JP Chapple, LA Metherell,ME Cheetham & AJL ClarkOC5 09.10 The overexpression Pit-1 pathway, switchon by Ret, get into apoptosis fateCM Cañibano Acebes, A Vidal, MG Borrello,C Diéguez & CV AlcarezOC6 09.25 Activation of androgen membranebinding sites induces potent regression ofprostate cancer cells in vitro and in vivoN Papadopoulou, M Kampa, A Gravanis,E Castanas & C StournarasOC7 09.40 The effect of bone marrow stem cell(BMSC) differentiation on growthhormone receptor (GHR)-associatedsignalling pathwaysMD Lewis, TE Easter, C El<strong>for</strong>d, ME Ludgate,BAJ Evans, DA Rees & MF ScanlonOC8 09.55 Role of the calcium-calmodulindependent kinase II in oncogenicras-induced proliferationAL Cavallo, M Illario, E Di Vito, S Monaco,G Fenzi, G Rossi & M Vitale08.10-10.10 Young Endocrinologists Session:Presenting your research -getting your work knownFORTH ROOMChair: W Arlt (Birmingham, UK)S102 08.10 Giving talksA McNeilly (Edinburgh, UK)S103 08.35 Practical tips <strong>for</strong> a perfect posterA Mostyn (Nottingham, UK)S104 09.00 Papers <strong>for</strong> peer-reviewed journalsS Pearce (Newcastle upon Tyne, UK)S105 09.25 PhD/MD thesis: a recipe <strong>for</strong> successD Abayasekara (London, UK)S106 09.50 Talking to a lay audienceT Parkhill (Bristol, UK)10.10-10.40 COFFEEHALL 310.40-11.25 <strong>Society</strong> <strong>for</strong> <strong>Endocrinology</strong>Transatlantic Medal LectureCLYDE AUDITORIUMChair: J Wass (Ox<strong>for</strong>d, UK)S3Nuclear receptors and transcriptionalcontrol of lipid metabolismD Mangelsdorf (Dallas, USA)11.35-12.20 Meet the Expert 1:MacroprolactinaemiaCLYDE AUDITORIUMChair: TBAP Chanson (Paris, France)11.35-12.20 Meet the Expert 2:Gestational diabetesLOMOND AUDITORIUMChair: D Johnston (London, UK)R Corcoy (Barcelona, Spain)www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>Sunday 2 April 2006 - continued11.35-12.20 Meet the Expert 3:Chips, arrays and biosensors:bioin<strong>for</strong>matics in endocrine researchHALL 1Chair: V Pirags (Riga, Latvia)A Turner (Leicester, UK)11.35-12.20 Meet the Expert 4:Cell immortalisation inendocrine researchFORTH ROOMChair: TBAS Kim (London, UK)12.20-13.50 Novartis PharmaceuticalsSatellite SymposiumFrom controversy to clarity inacromegaly managementFORTH ROOM13.50-14.50 POSTERS AND LUNCHHALL 314.50-16.50 Symposium 3:Cancer and the skeletonCLYDE AUDITORIUMChair: L Gennari (Sienna, Italy)S19 14.50 Mechanisms of malignant hypercalcaemiaP Clezardin (Lyon, France)S20 15.20 The management of malignanthypercalcaemiaP Selby (Manchester, UK)S21 15.50 Oncogenic osteomalacia: novel insightsinto the regulation of phosphatehomeostasisH Jueppner (Boston, USA)S22 16.20 Why does thyroid carcinoma metastasiseto bone?J Smit (Leiden, The Netherlands)14.50-16.50 Symposium 4:Cannabinoid signallingLOMOND AUDITORIUMChairs: C Tsigos (Athens, Greece) &M Korbonitz (London, UK)S23 14.50 Cannabinoids as modulators ofneuroendocrine signallingU Pagotto (Bologna, Italy)S24 15.30 Cannabinoids and feeding behaviourT Kirkham (Liverpool, UK)S25 16.10 Clinical applications of manipulation ofcannabinoid receptors (agonists)R Ross (Aberdeen, UK)14.50-16.50 Clinical Management Workshop 2:Management of complex genitalanomalies and the transition fromchildhood to adulthoodFORTH ROOMChair: A Grüters-Kieslich (Berlin, Germany)S78 14.50 Management of the infant withambiguous external genitalia. Thepediatric endocrinologist's approachC Dacou-Voutetakis (Athens, Greece)S79 15.30 Surgical management of ambiguousgenitalia in the infantC N Fékété (Paris, France)S80 16.10 Management of complex genitalanomalies and the transition fromchildhood to adulthood: a patient'sperspectiveP Carmichael (London, UK)14.50-16.50 Oral Communications 2:Steroids and reproductiveendocrinologyHALL 1Chair: I Huhtaniemi (London, UK)OC9 14.50 11β HSD1: anti-inflammatory mechanismin acute and chronic inflammation?AE Coutinho, M Gray, DA Sawatzky,D Brownstein, J Mullins, JR Seckl, JS Savill &KE ChapmanOC10*15.05OC11 15.20OC12 15.35OC13 15.50Progesterone signaling in humanmyometrium is mediated through twonovel membrane G protein-coupledreceptorsE Karteris, S Zervou, Y Pang, J Dong,EW Hillhouse, HS Randeva & P ThomasThe adrenal X-zone is involved inprogesterone inactivationF Beuschlein, L Heshkovitz, S Klammer,U Lichtenauer, I Shapiro, M Krup &Y WeinsteinExpression profiling of genes in the testisof rhesus macaques during developmentand agingHF Urbanski, VT Garyfallou, DR Lemos,JL Downs & DI BrownAnti-mullerian hormone (AMH)production by granulosa cells fromanovulatory PCO is 100 times higherthan from normal ovaries, but is inhibitedby met<strong>for</strong>minL Pellatt, L Hanna, D Feldman, P Malloy,H Brain, S Whitehead & H MasonPROGRAMMEwww.ece2006.com 17
8th European Congress of <strong>Endocrinology</strong>Sunday 2 April 2006 - continuedOC14 16.05OC15 16.20OC16 16.35Endometrial intracrinology: expression of3β-hydroxysteroid dehydrogenase(3βHSD), and 17β-hydroxysteroiddehydrogenase type 5 (17βHSD-5)SE McDonald, JI Mason & HOD CritchleyRole of the Hu proteins, HuR and HuD,and αCP1 in the regulation of androgenreceptor expression and activity inprostate cancer cellsCF Down, RR Lareu, B Granath, DJ Beveridge,H Furneaux, J Bentel & PJ Leedman17β-estradiol regulates pituitary AnxA1expression and externalization in vivo andin vitroEL Davies, HC Christian, S Omer,JC Buckingham & JF Morris16.50-17.30 TEAHALL 317.30-18.15 Plenary 1CLYDE AUDITORIUMChair: S Webb (Barcelona, Spain)S8Vitamin D actionR Bouillon (Leuven, Belgium)18.30-20.00 Ipsen Satellite SymposiumTailoring therapies <strong>for</strong> patientswith endocrine disordersCLYDE AUDITORIUMFrom 19.00The Sunday SocialTIGER TIGERPROGRAMME18www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>Monday 3 April 200607.15-08.00 Meet the Expert 5:Papillary thyroid cancermanagementCLYDE AUDITORIUMChair: I Szabolcz (Hungary)I Hay (Rochester, USA)07.15-08.00 Meet the Expert 6:Adrenal carcinomaLOMOND AUDITORIUMChair: M Terzolo (Orbassano, Italy)M Reincke (Munich, Germany)07.15-08.00 Meet the Expert 7:Transgenic techniquesHALL 1Chair: I Robinson (London, UK)M Poutanen (Turku, Finland)07.15-08.00 Meet the Expert 8:Pitfalls in signal transductionresearchFORTH ROOMChair: L Hunyady (Budapest, Hungary)W Knepel (Göttingen, Germany)08.10-10.10 Symposium 5:Novel peptides in reproductionCLYDE AUDITORIUMChairs: R Millar (Edinburgh, UK) &A Milewicz (Wroclaw, Poland)S26 08.10 The kisspeptin-GPR54 axisin reproductionM Tena-Sempere (Cordoba, Spain)S27 08.40 Use of recombinant leptin in womenwith hypothalamic amenorrheaC Welt (Boston, USA)S28 09.10 A genomic analysis of polypeptideligands and their receptors: examplesof relaxin and LGR familiesT Hsu (Stan<strong>for</strong>d, USA)S29 09.40 Novel recombinant gonadotropinmolecules in human reproductivedysfunctionB Mannaerts (Oss, The Netherlands)08.10-10.10 Oral Communications 3:Clinical endocrinologyHALL 1Chairs: M Grussendorf (Stuttgart, Germany) &S Lamberts (Rotterdam, The Netherlands)OC17 08.10Copeptin, a precursor of vasopressin, incritically ill patients - an observationalstudyM Christ-Crain, N Morgenthaler, J Struck,A Bergmann & B MuellerOC18 08.25OC19 08.40OC20 08.55OC21 09.10OC22 09.25OC23 09.40OC24 09.55Endoscope-assisted pituitary surgery <strong>for</strong>functioning and non-functioning pituitaryadenomas. The experience of the first 80patients in a single centrePL Hanson, SM Joshi, G Alusi, HI Sabin,WM Drake & JP MonsonDisease remission in long term treatedacromegalic patients after somatostatinanalogs withdrawalC L Ronchi, V Varca, A Lania, M Arosio,A Spada & P Beck-PeccozA European prospective real-lifeobservational study of quality of life inpatients with acromegalySM Webb, A Colao, P Caron, M Carvalheiro,E Ertürk, A Pokrajac-Simeunovic, J Schopohl,S Tsagarakis, IV Pearson, X Badia, S Caglio &B VincenziAdjuvant radiation therapy of the tumorbed prevents local recurrences inadrenocortical carcinomaM Fassnacht, S Hahner, B Polat, AC Koschker,M Flentje & B AllolioDetection of phaeochromocytoma: theemerging role of plasma metanephrinesRT Peaston, SG Ball, R Quinton, RA James,S Pearce, TWJ Lennard & RDG NeelyImproved prognosis in midgut carcinoidpatients by treating raised circulatingneurokinin A (NKA)JES Ardill, BJ Johnston, GB Turner, A McGinty& DR McCanceLow testosterone and atherogeniclipid profile in aging menJI Mäkinen, A Perheentupa, K Irjala,P Pöllänen, J Mäkinen, I Huhtaniemi &O Raitakari08.10-10.10 Symposium 6:Hot topicsLOMOND AUDITORIUMChairs: Pierre Bouloux (London, UK) &J Köhrle (Berlin, Germany)08.10 The obesity epidemic glutamate andumami regulation of food intakeJ Tresguerres (Madrid, Spain)08.35 Transthyretin and neuropeptide processingM Mendes Sousa (Porto, Portugal)09.00 Tissue specific effects of a novel plantderived SERM: 8-prenyl-naringeninWD Schleuning (Berlin, Germany)09.25 Genetic polymorphism redefine setpointsof the pituitary thyroid axisR Peeters (Rotterdam, The Netherlands)PROGRAMMEwww.ece2006.com 19
8th European Congress of <strong>Endocrinology</strong>PROGRAMME20Monday 3 April 2006 - continued09.50 Oligonucleotide microarrays and theirapplications in thyroid cancerB Jarzab (Gliwice, Poland)08.10-10.10 Symposium 7:Flies, worms and fish: use inendocrine researchFORTH ROOMChair: K Docherty (Aberdeen, UK)S30 08.10 Long live the worm: C. elgeans, insulinand agingD Gems (London, UK)S31 08.40 Dietary restriction and altered insulin/Igf1signalling: conserved mechanismsregulating lifespan in worms, flies androdentsD Withers (London, UK)S32 09.10 Giant flies and more: probing thefunctions and genetics of insulinsignalling in DrosophilaC Wilson (Ox<strong>for</strong>d, UK)S33 09.40 Specifying the cellular responses to IGFsignalling by IGF binding proteins: newlessons from the zebrafish modelC Duan (Ann Arbor, USA)10.10-10.40 COFFEEHALL 310.40-11.25 Clinical <strong>Endocrinology</strong> Trust VisitingProfessor LectureCLYDE AUDITORIUMChair: L Rees (London, UK)S4Understanding the genetic control ofpuberty in the humanW Crowley (Boston, USA)11.35-12.20 Meet the Expert 5:Papillary thyroid cancermanagementCLYDE AUDITORIUMChair: I Szabolcz (Hungary)I Hay (Rochester, USA)11.35-12.20 Meet the Expert 6:Adrenal carcinomaLOMOND AUDITORIUMChair: M Terzolo (Orbassano, Italy)M Reincke (Munich, Germany)11.35-12.20 Meet the Expert 7:Transgenic techniquesHALL 1Chair: I Robinson (London, UK)M Poutanen (Turku, Finland)11.35-12.20 Meet the Expert 8:Pitfalls in signal transductionresearchFORTH ROOMChair: L Hunyady (Budapest, Hungary)W Knepel (Göttingen, Germany)12.20-13.50 Shire Pharmaceuticals SatelliteSymposiumPCOS - The cruel face of a complexdiseaseFORTH ROOM12.20-13.50 Pfizer Satellite Symposium 1Young, middle-aged and elderlypatients with GHD: insights intoage-related responses to GHreplacementCLYDE AUDITORIUM13.50-14.00 <strong>Society</strong> <strong>for</strong> <strong>Endocrinology</strong> EGMCLYDE AUDITORIUM14.00-14.45 British Thyroid Association AGMALSH ROOM13.50-14.50 POSTERS AND LUNCHHALL 314.50-16.50 Symposium 8:Clinical lessons from novel aspectsof G protein-coupled receptorssignallingCLYDE AUDITORIUMChairs: A Spada (Milan, Italy) &A Breit (Marburg, Germany)S34 14.50 How the pattern of GPCR co-expressioncan regulate functionG Milligan (Glasgow, UK)S35 15.20 Alpha- and beta-adrenoceptordysfunctionL Hein (Würzburg, Germany)S36 15.50 Molecular pathology of the FSH receptorM Misrahi (Paris, France)S37 16.20 Therapeutic implications from newaspects in V2 vasopressin receptordysfunctionT Schöneberg (Leipzig, Germany)14.50-16.50 Clinical Management Workshop 3:Management of Graves'ophthalmopathyLOMOND AUDITORIUMChair: W Wiersinga (Amsterdam, TheNetherlands)S81 14.50 Prevention of thyroid eye diseaseG Krassas (Thessaloniki, Greece)www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>Monday 3 April 2006 - continuedS82 15.20 Medical treatmentC Marcocci (Pisa, Italy)S83 15.50 Alternative immunomodulatory therapies<strong>for</strong> Graves' ophthalmopathyJ Banga (London, UK)S84 16.20 Ophthalmic management of thyroid eyediseaseG Rose (London, UK)14.50-16.50 Basic Workshop:In vivo imaging of signallingHALL 1Chair: TBAS85 14.50 OPT: a novel wholemount imagingtechnology <strong>for</strong> visualising gene andprotein expressionS Wedden (Edinburgh, UK)S86 15.30 A mouse reporting on estrogen receptor(ER) transcriptional activity to understandthe complexities of female physiology inmammalsA Maggi (Milan, Italy)S87 16.10 Micro PET-ing in miceM Kreissl (Wuerzburg, Germany)14.50-16.50 Oral Communications 4:Diabetes and metabolismOC25 14.50OC26 15.05OC27 15.20FORTH ROOMChairs: R Corcoy (Barcelona, Spain) &H Romijn (Leiden, The Netherlands)Cannabinoids increase AMP-activatedprotein kinase (AMPK) enzyme activity inthe hypothalamus and heart via differentsignalling pathways - studies in CB1knockout animalsB Kola, M Christ-Crain, G Wittman,C Leontiou, A Grossman, C Fekete &M KorbonitsNeuropeptide S is a novel peptide, whichpotently stimulates the hypothalamopituitary-adrenalaxis and inhibits foodintakeKL Smith, M Patterson, WS Dhillo, SR Patel,NM Semjonous, JV Gardiner, MA Ghatei &SR BloomA selective increase in adipose 11β-HSD1expression in corticosterone-treatedPOMC-null mice is associated withdevelopment of metabolic syndromeZM Michailidou, APC Coll, NMM Morton,CJ Kenyon, S O'Rahilly, JR Seckl &KE ChapmanOC28 15.35OC29 15.50OC30 16.05OC31 16.20OC32 16.3516.50-17.30 TEA11β-Hydroxysteroid dehydrogenase type1 oxoreductase activity is increased inpatients with alcoholic chronic liverdisease: the key to the phenotype of thealcoholic pseudo-Cushing's state?A Ahmed, S Saksena, E Elias & PM StewartA choline deficient diet in mice preventshigh fat diet-induced insulin resistance inspite of more severe fatty liver diseasePJ Raubenheimer, MJ Nyirenda & BR WalkerThe release of the adipocytokine visfatinis regulated by glucose and insulinDG Haider, G Schaller, S Kapiotis, C Maier,A Luger & M WolztComparative analysis of the effects ofdehydroepiandrosterone (DHEA) onwhite and brown pre-adipocyteproliferation/differentiationSPL Rice, E Wang, MF Scanlon, M Ludgate &DA ReesThe in vitro effects of resistin on theinnate immune signalling pathway inisolated human subcutaneous adipocytesCM Kusminski, NF da Silva, AL Harte, S Kumar& PG McTernanHALL 317.30-18.15 Plenary 2S9CLYDE AUDITORIUMChair: B Ake Bengtsson (Sweden)Statins and rhabdomyolysisM Law (London, UK)18.30-20.00 Pfizer Satellite Symposium 2Clinical management ofacromegaly: applying 10 yearsof human experience withpegvisomantCLYDE AUDITORIUMFREE EVENINGPROGRAMMEwww.ece2006.com 21
PROGRAMME228th European Congress of <strong>Endocrinology</strong>Tuesday 4 April 200607.15-08.00 Meet the Expert 9:Medical management of Cushing'sdiseaseCLYDE AUDITORIUMChair: J Newell Price (Sheffield, UK)G Chrousos (Athens, Greece)07.15-08.00 Meet the Expert 10:Graves' ophthalmopathyLOMOND AUDITORIUMChair: P Perros (Newcastle upon Tyne, UK)W Wiersinga (Amsterdam, The Netherlands)07.15-08.00 Meet the Expert 11:Metabolic, functional and oncologicconsequences of altered GH/IGFexpressionHALL 1Chair: G Brockman (Berlin, Germany)P Jenkins (London, UK)07.15-08.00 Meet the Expert 12:Growth hormone deficiencyin adultsFORTH ROOMChair: D Johnston (London, UK)E-M Erfurth (Uppsala, Sweden)08.10-10.10 Symposium 9:Stromal cell-matrix interactionsLOMOND AUDITORIUMChair: G Williams (London, UK)S38 08.10 Role of heparan sulphates in neuronalstem cell differentiationJ Turnbull (Liverpool, UK)S39 08.40 Hormonal regulation of mesenchymalstem cell differentiation in boneF Jakob (Würzburg, Germany)S40 09.10 Cell adhesion molecules and osteoclastfunctionM Helfrich (Aberdeen, UK)S41 09.40 Wnt signalling in the stem cell nicheA Clark (Cardiff, UK)08.10-10.10 Symposium 10:Controversies in male healthCLYDE AUDITORIUMChair: M Maggi (Florence, Italy)S42 08.10 Does andropause exist?A Perheentupa (Turku, Finland)S43 08.40 Cardiovascular effects of androgensF Wu (Manchester, UK)S44 09.10 Endocrine regulation of prostatic growthZ Culig (Innsbruck, Austria)S45 09.40 Stem cell therapeutic approaches to maleinfertilityS Schlatt (Pittsburgh, USA)08.10-10.10 Oral Communications 5:Neuroendocrinology and neoplasiaFORTH ROOMChairs: S Tsagarakis (Athens, Greece) &I Gerendai (Budapest, Hungary)OC33 08.10OC34 08.25OC35 08.40OC36 08.55OC37 09.10OC38 09.25OC39 09.40OC40 09.55Effect of overexpression of GHsecretagogue receptor (GHSR) in thepituitary of transgenic miceLM Seoane, D Carmignac, FF Casanueva &ICAF RobinsonTransgenic mice overexpressing urocortin3 show increased anxiety and depressivelike behaviours but a hyporesponsiveACTH response to stressP M Jamieson, A Chen & W ValeImmunocytochemical colocalisation ofhormones in the human fetal pituitaryARM Chirculescu, C Badiu, JF Morris &M CoculescuSomatostatin analogues in the treatmentof acromegaly: correlation betweensomatostatin receptor subtype expressionlevels and clinical responseS Petersenn, A Redmann, DK Luedecke &K Mann90Y-dotatate in the treatment ofneuroendocrine tumoursD Handkiewicz-Junak, K Hasse-Lazar,B Jurecka-Lubieniecka, J Krajewska, J Roskosz,A Kukulska, S Szpak, A Krawczyk & B JarzabGermline mutations in patients withapparently sporadic pheochromocytomas/paragangliomasM Mannelli, MS Gaglianò, L Simi, T Ercolino,L Becherini, P Pinzani, R Sestini, GP Bernini,M Mascalchi & M Genuardi11β-hydroxysteroid dehydrogensemodulation of HPA function - importanceof genetic backgroundRN Carter, U Tworowska, JR Seckl &MC HolmesExpression of IGF-I and IGF-IR intamoxifen-sensitive and tamoxifenresistantbreast cancerCJ McVittie, S Khalaf, W Ogunkolade,R Carpenter, SA Bustin & PJ Jenkins08.10-10.10 Nurses Session:Metabolic syndromeALSH ROOMChairs: D Greenfield (Sheffield, UK) &S Shalet (Manchester, UK)S97 08.10 Leptin expands functionH Randeva (Coventry, UK)www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>Tuesday 4 April 2006 - continuedS98 08.35 Ghrelin updateV Popovic (Belgrade, Serbia and Montenegro)S99 09.00 Insulin resistance and type 2 diabetes -insights from the study of extremehuman phenotypesD Savage (Cambridge, UK)S100 09.25 Metabolic syndromeN Finer (Cambridge, UK)S101 09.50 Nurse-led weight management:the Counterweight ProgrammeL McCombie (Glasgow, UK)10.10-10.40 COFFEEHALL 310.40-11.25 British Thyroid Association Pitt-RiversLectureCLYDE AUDITORIUMChair: A Weetman (Sheffield, UK)S5Neurological abnormalities in mice with adominant negative thyroid hormone α1B Vennström (Stockholm, Sweden)11.35-12.20 Meet the Expert 9:Medical management of Cushing'sdiseaseCLYDE AUDITORIUMChair: J Newell Price (Sheffield, UK)G Chrousos (Athens, Greece)11.35-12.20 Meet the Expert 10:Graves' ophthalmopathyLOMOND AUDITORIUMChair: P Perros (Newcastle upon Tyne, UK)W Wiersinga (Amsterdam, The Netherlands)11.35-12.20 Meet the Expert 11:Metabolic, functional and oncologicconsequences of altered GH/IGFexpressionHALL 1Chair: G Brockman (Berlin, Germany)P Jenkins (London, UK)11.35-12.20 Meet the Expert 12:Growth hormone deficiencyin adultsFORTH ROOMChair: D Johnston (London, UK)E-M Erfurth (Uppsala, Sweden)12.20-13.50 European <strong>Society</strong> of <strong>Endocrinology</strong>AGMCLYDE AUDITORIUMfollowed by a drinks reception <strong>for</strong> attendees inthe Gala Foyer13.50-14.50 POSTERS AND LUNCHHALL 314.50-16.50 Symposium 11:How hormones get into cellsCLYDE AUDITORIUMChair: K Chapman (Edinburgh, UK)S46 14.50 Specific thyroid hormone transportersT Visser (Rotterdam, The Netherlands)S47 15.20 The spectrum of MCT8 gene mutationsH Krude (Berlin, Germany)S48 15.50 Multidrug resistance p-glycoprotein(Mdr-1): excluding corticosteroids frombrainE de Kloet (Leiden, The Netherlands)S49 16.20 Cell surface carrier-mediated transport ofsteroid hormonesJ Steffgen (Biberach, Germany)14.50-16.50 Symposium 12:<strong>Endocrinology</strong> in the fetusHALL 1Chair: TBAS50 14.50 Maternal thyroid function and cognitiveimpairment in childhoodA van Wassenaer (Amsterdam,The Netherlands)S51 15.20 Molecular basis of programming ofrenin-secreting cellsS Pennings (Edinburgh, UK)S52 15.50 Birth weight and later disease:genes and maternal diabetesR Lindsay (Glasgow, UK)S53 16.20 Endocrine therapy of the fetusA Grüters-Kieslich (Berlin, Germany)14.50-16.50 Clinical Management Workshop 4:Contrasting practices in EuropeanendocrinologyLOMOND AUDITORIUMChair: B Allolio (Wurzburg, Germany)S88/ 14.50 Diagnosis of hypercortisolismS89R Feelders (Rotterdam, The Netherlands) &A Atkinson (Belfast, UK)S90/ 15.30 New endocrinology medicines:S91when are they good value?A Walker (Glasgow, UK) &J Sandahl Christiansen (Aarhus, Denmark)S92/ 16.10 Contrasting practices in EuropeanS93endocrinology - radio-iodine therapyA Toft (Edinburgh, UK) &L Hegedüs (Odense, Denmark)www.ece2006.com 23PROGRAMME
8th European Congress of <strong>Endocrinology</strong>PROGRAMME24Tuesday 4 April 2006 - continued14.50-16.50 Oral Communications 6:Endocrine geneticsOC41 14.50OC42 15.05OC43 15.20OC44 15.35OC45 15.50OC46 16.05OC47 16.20OC48 16.25FORTH ROOMChairs: K Chatterjee (Cambridge, UK) &W de Herder (Rotterdam, The Netherlands)Mutations in cullin 7, a cofactor <strong>for</strong>ubiquitination, cause the 3M intra-uterinegrowth retardation syndromePE Clayton, L O'Sullivan, A Glaser,MH Oliveira, MRS de Alacantara,ES de Almeida Barretto, H Kingston, A Read,V Cormier-Daire, PJ Scambler & G BlackLinkage of a fourth gene <strong>for</strong> familialglucocorticoid deficiency to chromosome13qLA Metherell, C Becker, F Ruschendorf,D Naville, M Begeot, P Nurnberg, A Huebner,MO Savage & AJL ClarkMutation screening of SLC26A4 (PDS)gene in patients with Pendred syndromeand non-syndromic enlarged vestibularaqueductM Ladsous, V Vlaeminck-Guillem, C Vincent,F Dubrulle, V Dumur & JL WémeauFunctional impact of polymorphicvariation in the gene encoding 11βhydroxylase(CYP11B1): reduced adrenal11-hydroxylase efficiency identifies a keyintermediate phenotype in hypertensionM Barr, E Friel, SM MacKenzie, CD Holloway,EM Freel, NJR Brain, DM Wilkinson, M Ingram,R Fraser, AF Dominiczak, JMC Connell &E DaviesGenotype/phenotype correlation ofPRKAR1A mutations in patients withCarney complex (CNC) and/or sporadicprimary pigmented nodularadrenocortical disease (PPNAD) from theCNC networkL Groussin, F Rene-Corail, L Cazabat, E Jullian,E Clauser, X Bertagna & J BertheratPredictors and prevalence ofparaganglioma syndrome associated withmutations of the SDHC-geneHP NeumannFrequent involvement of BMP15 genevariants in women with prematureovarian failureE Di Pasquale, R Rossetti, A Marozzi, S Borgato,L Cavallo, F de Luca, S Einaudi, G Radetti, GRusso, M Sacco, P Beck-Peccoz & L PersaniProgressive osseous heteroplasia: aphenotype associated with mutations ofthe GNAS1 geneN Richard, G Abeguile & ML Kottler16.50-17.30 TEAHALL 317.30-18.15 <strong>Society</strong> <strong>for</strong> <strong>Endocrinology</strong>Dale Medal LectureCLYDE AUDITORIUMChair: J Wass (Ox<strong>for</strong>d, UK)S6From 19.30The actions of inhibin in endocrine tissuesJ Findlay (Clayton, Australia)Congress Banquet and CeilidhHILTON HOTELwww.ece2006.com
8th European Congress of <strong>Endocrinology</strong>Wednesday 5 April 200607.15-08.00 Meet the Expert 13:Pregnancy-related pituitarydisordersCLYDE AUDITORIUMChair: TBAF Kelestimur (Kayseri, Turkey)07.15-08.00 Meet the Expert 14:Hypoglycaemia and insulinomaLOMOND AUDITORIUMChair: TBAB Eriksson (Uppsala, Sweden)07.15-08.00 Meet the Expert 15:Interference in hormone assaysHALL 1Chair: J Barth (Leeds, UK)N Goncharov (Moscow, Russia)07.15-08.00 Meet the Expert 16:Mouse genetics in the identificationof quantitative traitsFORTH ROOMChair: S Kim (London, UK)G Brockman (Berlin, Germany)08.10-10.10 Symposium 13:Monogenic disorders illuminatemetabolic diseaseCLYDE AUDITORIUMChair: P Froguel (Lille, France)S54 08.10 Epidemic obesity in humansS O'Rahilly (Cambridge, UK)S55 08.40 Specific metabolic features in Prader-Labhart-Willi syndome (PWS) as indicatorsof the underlying genetic defectU Eiholzer (Zurich, Switzerland)S56 09.10 PPAR gamma and human metabolicdiseaseV Chatterjee (Cambridge, UK)S57 09.40 Learning from monogenic diabetes:insights into the fetal and adult β-cellA Hattersley (Exeter, UK)08.10-10.10 Symposium 14:Steroid hormone receptorsHALL 1Chairs: H Klocker (Innsbruck, Austria) &F Claessens (Leuven, Belgium)S58 08.10 The ups and downs of nuclear receptoraction in fat and fertilityM Parker (London, UK)S59 08.40 Chromatin remodelingF Gannon (Heidelberg, Germany)S60 09.10 Cell membrane receptors of steroidhormonesJ Brosens (London, UK)S61 09.40 Lysine modifications in transcriptionalregulation by steroid receptorsJ Palvimo (Helsinki, Finland)08.10-10.10 Symposium 15:Anabolic hormones in sportLOMOND AUDITORIUMChairs: G Tolis (Athens, Greece) &C Strasburger (Berlin, Germany)S62 08.10 Overview of anabolic steroids in sportK Kuoppasalmi (Helsinki, Finland)S63 08.40 Detecting growth hormone abuse inathletesC Strasburger (Berlin, Germany)S64 09.10 Gene doping: will the age of genetherapy usher in the age of geneticenhancement?H Sweeney (Pennsylvania, USA)S65 09.40 ErythropoietinD Cowan (London, UK)08.10-10.10 Oral Communications 7:Calcium and boneFORTH ROOMChair: TBAOC49*08.10OC50 08.25OC51*08.40OC52 08.55OC53 09.10The A990G polymorphism of calciumsensing receptor gene (CASR) isassociated with nephrolithiasis in patientswith primary hyperparathyroidism (PHPT)C Eller-Vainicher, M Filopanti, G Vezzoli,L Soldati, P Saeli, P Beck-Peccoz, A Spada &S CorbettaCongenitally hypothyroid mice with(Pax8-/-) or without (hyt/hyt) functionalTSH receptors (TSHR) display equivalentskeletal phenotypesGR Williams, R Swinhoe, E Murphy,AJ Williams, S Costagliola, G Vassart,PGT Howell, A Boyde, F Flamant, J Samarut,R Weiss, S Refetoff & JHD BassettTSH receptor action in osteoblasts andosteoclasts in vitroE Murphy, AJ Williams, TM Galli<strong>for</strong>d,S Costagliola, G Vassart, JHD Bassett &GR WilliamsIn acromegaly, bone mineral densitydepends on gonadal functionM Kochman, W Zgliczynski, W Misiorowski,P Zdunowski, L Papierska & S ZgliczynskiBone involvement in patients withadrenal incidentalomas: role of subclinicalhypercortisolismI Chiodini, F Coletti, P Epaminonda,S Di Lembo, V Morelli, B Masserini, G Adda &M ArosioPROGRAMMEwww.ece2006.com 25
8th European Congress of <strong>Endocrinology</strong>PROGRAMME26Wednesday 5 April 2006 - continuedOC54 09.25OC55 09.40OC56 09.5510.10-10.40 COFFEEHALL 3Adult mice harbouring a dominantnegative R384C mutation of TRα1 have amarked increase in trabecular bone andmicro-mineralisation densityJHD Bassett, K Nordstrom, B Vennstrom,PGT Howell, A Boyde & GR WilliamsThyroid hormones stimulate osteoblastdifferentiation but inhibit mineralizationof bone nodules in vitroAJ Williams, JC Barnard, JHD Bassett &GR WilliamsThe Scandinavian investigation of primaryhyperparathyroidism (pHPT) - end ofinclusion and preliminary resultsJB Bollerslev, SJ Jansson, CLM Mollerup,JN Nordenström, EL Lungren, OT Tørring,CF Franco, JEV Varhaug, GAI Isaksen &TR Rosen10.40-11.25 Clinical <strong>Endocrinology</strong> Trust LectureS711.35-12.20 Plenary 3CLYDE AUDITORIUMChair: L Rees (London, UK)Thyroid disease paradigms and problemsA Weetman (Sheffield, UK)LOMOND AUDITORIUMChair: P Bouchard (Paris, France)S10 Stem cells: regeneration in type 1diabetesM Trucco (Pittsburgh, USA)11.35-12.20 Debate:Met<strong>for</strong>min is the treatment ofchoice <strong>for</strong> polycystic ovariansyndromeCLYDE AUDITORIUMChair: S Franks (London, UK)For the motion: R Fleming (Glasgow, UK)Against the motion: A Balen (Leeds, UK)12.20-13.05 Meet the Expert 13:Pregnancy-related pituitarydisordersCLYDE AUDITORIUMChair: TBAF Kelestimur (Kayseri, Turkey)12.20-13.05 Meet the Expert 14:Hypoglycaemia and insulinomaLOMOND AUDITORIUMChair: TBAB Eriksson (Uppsala, Sweden)12.20-13.05 Meet the Expert 15:Interference in hormone assaysHALL 1Chair: J Barth (Leeds, UK)N Goncharov (Moscow, Russia)12.20-13.05 Meet the Expert 16:Mouse genetics in the identificationof quantitative traitsFORTH ROOMChair: S Kim (London, UK)G Brockman (Berlin, Germany)13.05-13.35 LUNCHHALL 313.35-15.35 Symposium 16:Disorders of melanocortinreceptor functionsLOMOND AUDITORIUMChair: H Biebermann (Berlin, Germany)S66 13.35 MC1R variants: Mendle is quite complexenoughJ Rees (Edinburgh, UK)S67 14.05 Identification of the genes causing ACTHinsensitivityA Clark (London, UK)S68 14.35 Melanocortin receptor mutations inhumansP Froguel (Lille, France)S69 15.05 Gs-independent signalling ofmelanocortin-4 receptorsA Breit (Marburg, Germany)13.35-15.35 Symposium 17:Endocrine oncogenesis andmanagement of hereditaryendocrine tumoursCLYDE AUDITORIUMChairs: B Kos Kudla (Zabrze, Poland) &E Rossella (Pisa, Italy)S70 13.35 RET function and dysfunctionL Fugazzola (Milan, Italy)S71 14.05 Novel management strategies inmedullary carcinoma of the thyroidJ Feldkamp (Bielefeld, Germany)S72 14.35 Hypoxia inducible factor (HIF) andphaeochromocytomaC Pugh (Ox<strong>for</strong>d, UK)S73 15.05 Familial phaeochromocytomasP Plouin (Paris, France)www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>Wednesday 5 April 2006 - continued13.35-15.35 Clinical Management Workshop 5:Research management workshopHALL 1Chair: C Meir (Geneva, Switzerland)S94 13.35 Better management of ethical review inEuropean medicine developmentI Klingmann (Brussels, Belgium)S95 14.15 Impact of the EU Clinical Trials Directiveon academic researchB Moulton (Dublin, Ireland)S96 14.55 Funding <strong>for</strong> commercialisation of researchafter the biotech bubbleRN Seabrook (London, UK)13.35-15.35 Oral Communications 8:ThyroidFORTH ROOMChairs: M Alevizaki (Athens, Greece) &M Colculescu (Bucharest, Romania)OC57 13.35OC64 13.50OC59 14.05OC60 14.20OC61 14.35OC62*14.50Treatment of experimental hyperthyroidGraves' disease with decoy TNF-familyligand receptors suggests an essential role<strong>for</strong> BAFF in production of thyroidstimulating antibodiesJA Gilbert, SL Kalled, J Moorhead, D Hess,P Rennert, Z Li, Z Khan & J-P BangaThyroid hormone receptor TRβ1 mediatesAkt activation by T3 in pancreatic β cellsSM Misiti, CV Verga Falzacappa, VP Patriarca,SM Michienzi, AS Stigliano, EB Brunetti &VT ToscanoTri-iodothyronine improveshaemodynamic per<strong>for</strong>mance and isassociated with improved myocardialprotection post on-pump coronary arterybypass graftingAM Ranasinghe, DW Quinn, TR Graham,BE Keogh, CJ Mascaro, SJ Rooney, IC Wilson,D Pagano, JA Franklyn & RS Bonser4-Methylbenzylidene-camphor (4MBC)causes pituitary effects comparable tohypothyroidismIH Hamann, C Schmutzler, P Kirschmeyer,H Jarry & J KöhrlePhosphodiesterase-resistant PKA Iagonists inhibit thyroid cancer cellgrowthS Lucchi, D Calebiro, T de Filippis, P Porazzi,P Beck-Peccoz & L PersaniThe role of the thyroid hormonetransporter monocarboxylate transporter8 (MCT8) in fetal brain developmentSR James, CJ McCabe, VE Smith, SY Chan,TG Barrett, JA Franklyn & MD KilbyOC63 15.05OC58 15.20Gender-specific differences in theexpression of deiodinase I (Dio1) inmammalsC Riese, U Schweizer, J Köhrle & L SchomburgInterleukin 1: the optimal cytokine targetin thyroid-associated ophthalmopathy?TJ Cawood, P Moriaty, C O'Farrelly &D O'Shea15.35 Novartis Oncology Young InvestigatorAward and BTA Award Announcementsand Close of MeetingCLYDE AUDITORIUMChair: S Lamberts (Rotterdam, TheNetherlands)PROGRAMMEwww.ece2006.com 27
IN TREATING ACROMEGALYWhat Matters MostGH ControlIGF-I ControlTumour ShrinkageSymptom ControlABBREVIATED PRESCRIBING INFORMATIONIndications: Treatment of patients with acromegaly:For symptomatic control and reduction of GH and IGF 1 levelsin patients with acromegaly:• who are adequately controlled on s.c. treatment withSandostatin, in whom surgery, or radiotherapy isinappropriate or ineffective, or in the interim period untilradiotherapy becomes fully effective.• In short term (3-12 months) treatment prior to pituitary surgeryGEP Tumours: Relief of symptoms of gastroenteropancreatic(GEP) tumours including carcinoid tumours, VIPomasand glucagonomas, in patients whose symptoms areadequately controlled on s.c. treatment with Sandostatin.Sandostatin is not antitumour therapy and is not curative in thesepatients.Presentation: Long-acting depot injection <strong>for</strong>m of octreotide(as acetate): 10, 20 or 30 mg per vial each supplied withvehicle.Dosage and Administration: Sandostatin LAR may only beadministered by deep intragluteal injection. The site of repeatintragluteal injections should be alternated between the left andright gluteal muscle.AcromegalyAdults: Deep intragluteal injection starting with 20 mg at 4weekly intervals <strong>for</strong> 3 months in patients who have hada test dose of s.c. Sandostatin or who are adequately controlledwith s.c. Sandostatin. Adjust according to clinical andbiochemical response. Dose can be increased to 30 mg every4 weeks.GEP tumoursAdults: Deep intragluteal injection starting with 20 mg at 4weekly intervals <strong>for</strong> 3 months in patients adequately controlledon usual therapeutic range of s.c. Sandostatin. Treatment withs.c. Sandostatin should be continued at the previously effectivedosage <strong>for</strong> 2 weeks after the first injection of Sandostatin LAR.Assess response after 3 months. Adjust according to clinical andbiochemical response (range 10 mg to 30 mg every 4 weeks).Children: Limited data available.Contra-Indications: Hypersensitivity to octreotide or anycomponents of <strong>for</strong>mulation.Precautions: Monitor glucose tolerance and antidiabetictreatment in patients with diabetes mellitus. The depth andduration of hypoglycaemia may be increased in patients withinsulinoma. As GH-secreting pituitary tumours may sometimesexpand, causing serious complications (e.g. visual field defects),it is essential that all patients are carefully monitored. Ultrasonicexamination of the gallbladder be<strong>for</strong>e and at about 6 monthlyintervals during Sandostatin LAR therapy is recommended. Donot use during pregnancy or lactation.Interactions: Cyclosporine, cimetidine, bromocriptine.Somatostatin analogues may decrease the clearance of drugsmetabolised by CYP3A4, particularly those which have a lowtherapeutic index (e.g. carbamazepine, digoxin, warfarin andterfenadine). Caution should be exercised during coadministrationof octreotide and these drugs.Side-Effects: Pain and rarely, swelling and rash at injectionsite. Anorexia, nausea, vomiting, abdominal pain or bloating,flatulence, loose stools, diarrhoea and steatorrhoea. In rareinstances, gastrointestinal side-effects may resemble acuteintestinal obstruction, with progressive abdominal distension,severe epigastric pain, abdominal tenderness and guarding.Gallstones can develop during long-term treatment. Persistenthyperglycaemia, hepatic dysfunction, hypoglycaemia, transientalopecia and acute pancreatitis have been reported rarely. Veryrare cases of hypersensitivity have been reported. Refer to theSPC <strong>for</strong> a full list of all side-effects.©2006 Novartis Pharma AG 2/06 SAN06000004–February 2006
8th European Congress of <strong>Endocrinology</strong>Attended PostersPosters will be displayed throughout the conference, and will be presented at 14.00-14.50 on the following dates:Topic Poster numbers DateBone P1-P46 Sunday 2 AprilClinical case reports P47-P89 Sunday 2 AprilClinical case reports P90-P132 Monday 3 AprilClinical case reports P133-P174 Tuesday 4 AprilClinical practice and governance P175-P210 Monday 3 AprilComparative endocrinology P211-P217 Tuesday 4 AprilCytokines and growth factors P218-P250 Tuesday 4 AprilDiabetes, metabolism and cardiovascular P251-P308 Sunday 2 AprilDiabetes, metabolism and cardiovascular P309-P367 Monday 3 AprilDiabetes, metabolism and cardiovascular P368-P425 Tuesday 4 AprilEndocrine disruptors P426-P436 Tuesday 4 AprilEndocrine tumours and neoplasia P437-P475 Sunday 2 AprilEndocrine tumours and neoplasia P476-P513 Monday 3 AprilEndocrine tumours and neoplasia P514-P552 Tuesday 4 AprilGrowth and development P553-P574 Sunday 2 AprilNeuroendocrinology and behaviour P575-P609 Monday 3 AprilNeuroendocrinology and behaviour P610-P644 Tuesday 4 AprilReproduction P645-P686 Sunday 2 AprilReproduction P687-P726 Tuesday 4 AprilSteroids P727-P770 Monday 3 AprilThyroid P771-P828 Sunday 2 AprilThyroid P829-P886 Tuesday 4 AprilThyroid P887-P944 Monday 3 Aprilwww.ece2006.com 29POSTERS
8th European Congress of <strong>Endocrinology</strong>POSTERSBoneP1P2P3An audit of the role of Sestimibi imaging ofthe parathyroid glands in the management ofparathyroid diseaseD Gable, J Bomanji & G ConwayDoes adrenal function influence bone status inprimary hyperparathyroidism? Preliminaryresults in a large series of patients at the timeof the diagnosisL Gianotti, F Tassone, A Pia, P Razzore, F Cesario,G Magro & G BorrettaThe effect of local radiotherapy onosteoprotegerin levels in patients with bonemetastasesA Abdulkhaliq, C Foo, G Baffoe, P Anand, SI Girgis& C QuigleyP4 Clinical aspects of diabetic osteoarthropathy intype 1 and type 2 diabetes mellitus patientsAP Shepelkevich & DI RomeikoP5 Osteoporotic fractures in old subjects: role offunctional and nutritional status and therapyeffects during one year after fractureF Magri, V Valdes, V Guazzoni, M Cupri, L Chiovato& E FerrariP6 Circulating osteoprotegerin and receptoractivator of NF-κB ligand system in patientswith beta-thalassemia majorN Angelopoulos, G Rombopoulos, D Kaltsas,V Kaltzidou, E Katounda & G TolisP7 The role of genetic individuality andphytoestrogens with minerals in preventionand treatment of postmenopausalosteoporosisI-O Vaasa, M Roosalu, S Teesalu & I KalitsP8 Is there any combined influence of the N363Spolymorphism in the glucocorticoid receptorgene and the BsmI polymorphism in thevitamin D receptor gene on the occurrence ofglucocorticoid-induced osteoporosis inpatients with bronchial asthma?U Tworowska, B Bidzinska-Speichert, A Obojski,M Demissie, JW Koper & R SlezakP9 Bone mineral density in patients with type 1diabetesE Giorgadze, M Tsagareli, N Jikurauli & N SvaniP10P11Thyroid hormone receptor alpha has a criticalnegative role in maintenance of the adultskeletonJHD Bassett, PJ O'Shea, A Boyde, PGT Howell,J Samarut, O Chassande & GR WilliamsPTH and phosphate circadian rhythms arealtered in adult growth hormone deficientpatients with low bone mineral densityHD White, AM Ahmad, BH Durham, WD Fraser &JP VoraP12P13P14P15P16P17P18P19P20P21P22Oral phosphate therapy used as an adjunct togrowth hormone in adult growth hormonedeficiency results in greater changes in bonemineral density compared with growthhormone replacement aloneHD White, AM Ahmad, BH Durham, WD Fraser &JP VoraPolymorphism in farnesyl pyrophosphatesynthase(FDPS) gene and relation with BMDand response to aminobisphosphonatetreatmentS Silvestri, S Carbonell, AB Thomsen, Y Bagger,C Christiansen & ML BrandiDo different generations of PTH assay inducedifferent diagnosis in renal bone disease?A Gendrot, A Georges, C Lasseur, L Bordenave &J-B CorcuffManagement of primary hyperparathyroidism- are we following consensus guidelines?KK Gangopadhyay, A Gurubili, D Nair & P DeValue of qualitative bone histology assessmentin the evaluation of subjects with primaryosteoporosisCE Georgescu, T Seck, HW Minne, R Ziegler,I Duncea, L Gozariu & J PfeilschifterHearing impairment increases risk of bonefractures in women with Turner's syndromeTS Han, GS Conway & B CadgeEvaluation of bone mineral density andmarkers of bone turnover in haemodialysispatientsA Zygmunt, I Kurnatowska, J Fijalkowska-Morawska, J Bialkowska, M Jablkowski, M Nowicki& A LewinskiThe effect of ceramide on IGF-I inducedproliferation in growth plate chondrocytesVE MacRae, SF Ahmed & C FarquharsonTreatment and follow-up of primaryhyperparathyroidism: 50 casesH Cheikhrouhou, I Hadj Ali, K Khiari &N Ben AbdallahIs there any relationship between the BsmIand FokI polymorphisms in the vitamin Dreceptor gene and bone mineral density inmen?J Kuliczkowska-Płaksej, A Trzmiel, A Filus,U Tworowska, D Jedrzejuk & A MilewiczMutational analysis of the PHEX gene infamilial and sporadic cases of X-linkedhypophosphatemia (XLH)S Clausmeyer, PC Clemens, E Schulze & F Raue30www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P23P24P25P26P27P28P29P30P31P32The reduction of bone mineral density inpost-menopausal women with primaryhyperparathyroidism is higher in the presenceof concomitant GH hormone secretionimpairmentE Cecconi, M Genovesi, F Bogazzi, L Grasso,M Procopio, C Marcocci, A Pinchera, L Bartalena,E Martino & M GasperiEffect of melatonin on gene expression andmineralization in mouse osteoblast cultureD Manda, C Busu, O Ianas, G Stefanovici,R Calarasu, D Grigorie & C DumitracheEffects of growth hormone administration onparathyroid hormone sensitivity and bonemineral metabolism in establishedosteoporosisF Joseph, A Ahmad, HD White, A Joshi, B Durham,S Vinjamuri, K Ashawesh, WD Fraser & JP VoraIs 1g of calcium and 800IU of vitamin Dsufficient to replenish vitamin D stores inpostmenopausal women with low bonedensity?T Sathyapalan, M Bottazzi, C Walton &P AlbertazziSynergistic induction of osteoblastic localglucocorticoid metabolism by inflammatorycytokines and glucocorticoids: a novelmechanism <strong>for</strong> glucocorticoid-induced bonediseaseK Kaur, R Hardy, PM Stewart, EH Rabbitt,M Hewison & MS CooperEvidence <strong>for</strong> high prevalence of hormonalirregularities in male osteoporosisS Goebel, C Riegel, L Seefried, B Saller & F JakobEvaluation of bone markers and structure insubclinical Cushing's syndromeM Monesi, MR Ambrosio, S Taroni, M Bondanelli,MC Zatelli & EC degli UbertiAsymptomatic primary hyperparathyroidism:preliminary results of a prospectiverandomized study on the effect ofparathyroidectomyE Ambrogini, L Cianferotti, E Vignali, F Cetani,G Viccica, A Picone, P Miccoli, A Pinchera &C MarcocciBrown tumors in a patient with glutenenteropathy and masked primary (or tertiary)hyperparathyroidismK Jacob, J Sudagani, M Davies & P SelbyBaseline characteristics of postmenopausalGreek women with osteoporosis who had aninadequate response to antiresorptivemedicationsA Ginis, E Charalampidou & N Thalassinos and theHellenic OSSO Study GroupP33P34P35P36P37P38P39P40P41P42P43Effect of grape procyanidins on TNF alphamRNA expression and cell DNA damage inMC3T3-E1 osteoblast-like cells in vitroJY Zhong & LH ZhangThe effects of dexamethasone anddehydroepiandrosterone (DHEA) on cytokinesand receptor expression in a humanosteoblastic cell line: potential steroid-sparingrole <strong>for</strong> DHEAG Harding, YT Mak, B Evans, J Cheung,D MacDonald & G HampsonAssessment of bone health and bodycomposition in Glasgow school childrenR Rashid & SF AhmedAssessment of bone mineral density (BMD) inpatients with adrenal incidentaloma (AI):comparison between dual-energy X-rayabsorptiometry (DEXA) and quantitativeultrasonometry (QUS)G Reimondo, S Bovio, M Ventura, G Osella, A Angeli& M TerzoloA comparative study of neck ultrasonography,Sestamibi scan and parathyroid surgeryfindingsKCS Dixit, AJ Norris, PG Wiles, MW Savage,AN Khan & A GandhiGlucocorticoid metabolism in mouseosteoblasts: a model <strong>for</strong> the effects of localglucocorticoid generation on boneR Crook, K Hewitt, PM Stewart, EH Rabbitt &MS CooperLong-term growth hormone (GH) replacementin GH deficient adults - favourable effect onbone and body compositionV Hána, J Cáp, T Vas˘átko & JJ StepánDoes parathyroidectomy reduce the risk offractures and renal stones? Results of asystematic review and meta analysisBE Sanders, M Davies & PL SelbyBrown tumors in hyperparathyroidism may bemistaken <strong>for</strong> primitive bone neoplasia: reportof two casesCA Rota, F Ingraudo, RM Paragliola, MP Ricciato,AL Bilotta, F Ianni, F Gallo, G Ubertini, SM Corsello& A PontecorviThe effect of once-weekly risedronate onbiochemical markers of bone turnover afterthree months of treatmentD Paun, D Grigorie, A Ghemigian, F Cofaru &C DumitracheQuantitative ultrasound at the hand phalangesin patients with acromegalyM Bolanowski, W Pluskiewicz & J Daroszewskiwww.ece2006.com 31POSTERS
8th European Congress of <strong>Endocrinology</strong>POSTERS32P44P45P46Selenium supplementation restores theantioxidative capacity and prevents celldamage in mesenchymal stem cells in vitroR Ebert, M Ulmer, S Zeck, J Meissner-Weigl,D Schneider, H Stopper, N Schupp, M Kassem &F JakobExpression of the membrane-associatedhormone-sensitive protein UO-44 in hMSC-TERT immortalized mesenchymal stem cellsL Seefried, R Ebert, M Kassem & F JakobThe effect of once-weekly risedronate onbiochemical markers of bone turnover afterthree months of treatmentD Paun, D Grigorie, A Ghemigian, F Cofaru &C DumitracheClinical case reportsP47 Forced conservative management of a patientwith pituitary tumour apoplexy and reducedconscious levelA Advani, RA James, A Jenkins, JH Parr, J Scott,R Cooper & ST WahidP48 An unusual presentation of 'fits'S Dissanayake, M Lazdam, V Basker, A Fryer,RC Strange, M Deaken & F HannaP49P50P51P52P53P54P55P56An unusual cause of confusionA Tahrani & P MoulikRecurrent congenital neonatalhyperthyroidism in a mother with Graves'disease (post radio-ablation) on thyroxinereplacementJ Kumar, P Rajendran, R Lapworth, C Buchanan &C WilliamsIsolated ACTH deficiency following long-termbenzodiazepine treatmentK Müssig, E Friess, K Mörike, H-U Häring &D OverkampInfertility and bilateral testicular masses due to21-hydroxylase deficiencyK Müssig, S Kaltenbach, C Maser-Gluth,MF Hartmann, SA Wudy, M Horger, B Gallwitz,F Raue, H-U Häring & E SchulzeGraves' eye disease following radioiodinetreatment <strong>for</strong> toxic nodular goitreA Tahrani & P MoulikRecurrent hypoglycaemia: an unusualassociation of islet cell hyperplasia and coeliacdiseaseRS Moisey, D Wright & SR PeaceyScreening of osteoporosis in a small RomaniantownS Mandasescu & MM TriscaAcute myocardial infarction and Graves'thyrotoxicosisRA Chudleigh, PJD Owen, S Bhattachrya &JS DaviesP57 Acromegaly, pregnancy and diabetes mellitus -a successful maternal and foetal outcomeSS Seshadri, D Wright, DC Whitelaw & SR PeaceyP58P59P60P61P62P63P64P65P66P67P68P69Surgical management of metastaticphaeochromocytoma: review of 2 casesTH El-Tawil, KH Darzy, R Carpenter, S Bhattacharya,S Edmondson & JP MonsonThe coincidence of mucoepidermoid andpapillary thyroid carcinoma. A case reportGL Kovacs, F Salamon, Z Gorombey, L Kovacs,E Hubina, MI Goth & I SzabolcsDIre Straits - hypothalamic diabetes insipidus,acute myeloid leukaemia and high riskcytogenetics: 45,XX,t(3;3)(q21q26),-7KS Myint, M Besser, J Craig, D Halsall, H Simpson,DF Wood, VKK Chatterjee & M GurnellMetastatic insulinoma or not?KS Myint, RK Semple, I MacFarlane, D Appleton,RK Praseedom, H Simpson, DF Wood,VKK Chatterjee & M GurnellAPECED (autoimmune polyendocrinopathycandidiasis-ectodermaldystrophy) syndromewith atypical or incomplete presentation:report of 4 cases with AIRE gene mutations inheterozygosityC Mazza, I Sparapani, L Costa, S Zanola,M Filisetti, A Pilotta, F Lombardi, MI Spagnuolo,G Valerio, A Franzese, G Radetti & F BuziRelationship between age of onset, naturalcourse and therapeutic approach in patientswith acromegalyEI Marova, VS Pronin, SE Agadzanjan,NN Molitvoslovova, MB Antsiferov & TM AlexeevaSweet's syndrome and thyroid diseases:is there a link?F Magri, E Gabellieri, AR Sorrentino, MI Rizza,L Chiovato & E FerrariBone marrow hypoplasia in a patient withpanhypopituitarism responsive to sexhormone therapy. The importance ofcompliance with testosterone therapyMA Badawi, FS Farah, MY Elkhalifa, A Al-Humaidi &TA ElhaddMultiple endocrine neoplasia type 1 (MEN1)in a patient with systemic mastocytosisA Jönsson, C Grännö, J Järhult & G RoupeBrown tumour of the maxilla as the presentingfeature of parathyroid carcinomaAJ Watt, T Gruning & DEH FlanaganUnexpected detection of thyroid cancer in apatient with presumed Graves' thyrotoxicosisAJ Watt, T Gruning & DEH FlanaganPrimary hyperparathyroidism (PHPT): still acause of hypertension resistant to therapyAP Baptista, EC Morgado, AP Silva & PL Neveswww.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P70P71P72P73P74P75P76P77P78P79P80P81P82P83Spontaneous pregnancy after trans-sphenoidalsurgery in a patient with pituitary hypophysitis- a case reportH Siddique, V Baskar, S Dissanayeke, RN Clayton &FWF HannaAdipsic diabetes insipidus following pituitarysurgery <strong>for</strong> a macroprolactinomaM Sherlock, A Agha, D Smith, R Crowley &C ThompsonRegression of somatotropinoma in the courseof treatment with octreotide in a femalepatient with acromegalyB Matuszek, M Lenart-Lipińska & A NowakowskiFamilial hyperparathyroidism with a mutationin the HRPT2 geneP Goulden, G Bano, VK Ajith Kumar, SV Hodgson &SS NusseyPendred's syndrome with three mutationsP Goulden, G Bano, VK Ajith Kumar, SV Hodgson &SS NusseyAbout three cases of Riedel thyroiditisMC Vantyghem, S Marcelli-Tourvieille, J Schmidt,B Néraud, P Perimenis, E Leteurtre, C Cardot-Bauters, F Pattou, B Carnaille & JL WémeauParathyroid carcinoma in a patient withchronic renal failure on long-term dialysisMR Diaconescu, M Glod & I CosteaShould prophylactic thyroidectomy be carriedout in mucosal neuroma syndrome?G Spyer, S Ellard, P Turnpenny, A Hattersley &B VaidyaSynchronous malignant para-aorticphaeochromocytoma and vagal nerveparaganglioma in a patient with germlineSDHB mutationRW McCallum, P Stanton, S Walker,V Parameswaran & T GreenawayOphthalmic presentations of Cushing'ssyndromeIM Ibrahim, A Al-Bermani & RA JamesLong-term outcome of untreated Cushing'ssyndrome due to pituitary microadenomaL Nduwayo, J Othmani & P RousseauxInvasive prolactinoma with multiplerecurrences: pituitary atypical adenoma orpituitary carcinoma? Report of a caseL Gomes, I Paiva, C Ribeiro, F Gomes, M Rito,O Rebelo & M CarvalheiroA case of primary pigmented micronodularhyperplasia as a cause of Cushing's syndromeA Akalin, O Son, S Isiksoy, N Kebapci & B EfeEndocrine evaluation in a man with restrictiveeating disorderM Moro, L Danesi, N Polli, E Rasi, B Filippini,M Andrioli, M Scacchi & F CavagniniP84 Hypopituitarism in an adult thalassemicpatient. Effects of different replacementtherapiesL Danesi, A Cattaneo, E Lavezzi, M Scacchi &F CavagniniP85 Langerhans cell histiocytosis; managementdilemma <strong>for</strong> the adult endocrinologist!IM Ibrahim, E-L Lim, S Razvi, SHS Pearce, N Leach,R Quinton, D Mitra, J Wilsdon, A Baborie,S Johnson, AD Burt, K Wood, G Jones, K Windebank,J Pritchard, CO Record & SMM BennettP86 A case of bacterial endocarditis in a patientwith acromegalyG Bassotti, D Di Sarra, D Pietrobono, T D'Amico,P Gargiulo & G TamburranoP87 Gitelman's syndrome in pregnant, type 1diabetic patient presented with foetal growthretardation, and bilateral hydronephrosis andhydroureterMA Elrishi, A Kilvert, B Sirnivasan & I LawrenceP88 The prolonged progressive course ofacromegaly, complicated with diabetesmellitus, bilateral gonarthropathy, thyroidpathology and severe papillomatosis (clinicalobservation)TS Kamynina, AV Dreval & JG PokramovichP89P90P91P92P93P94P95P96P97A case of adult GH deficit in a woman withautoimmune polyendocrine syndrome type IID Pietrobono, G Bassotti, F Diacono, R Iuorio,V Mercuri & P GargiuloSpontaneous thrombosis of ophthalmic arteryaneurysm causing isolated cortisol deficiencyA Zia, F Joseph, S Basu, TRK Varma & JP VoraAortic involvement in Turner syndromeM Ilyas, SL Atkin, V Mathew, C Chu & D EttlesPurely adrenaline-secretingphaeochromocytoma: a classical presentationof a rare entityA Merghani, KH Darzy, D Morris, R Carpenter,A Deaner & JP MonsonA scary awakening - acute paralysis in a youngmanLV Forrest & JK PlattsSystemic amyloidosis presenting withthyrotoxicosis: a case reportG Fegan, S Rasbridge & M TaylorUnusual case of pseudohypoparathyroidismtype IBLCH Ciin & T DornanA case of Cushing's syndrome and rapidcourse of illnessJ Sudagani, K Jacob, S Anwar, C Gibson, JRE Davis& FCW WuPrimary adrenal insufficiency, gonadal failureand weak legsJ Sudagani, K Jacob, S Anwar, C Gibson, JRE Davis& FCW Wuwww.ece2006.com 33POSTERS
8th European Congress of <strong>Endocrinology</strong>P98Hypocalcemic cardiomyopathy in a patientwith primary hypoparathyroidism and Fahr'sdiseaseS Azzoug & F ChentliP112Three generations of generalised resistance tothyroid hormone (GRTH)SC McGeoch, WA Watson, E Stephen, H Watson,A Mayo, P Abraham & JS BevanP99P100P101P102An unusual case of panhypopituitarismassociated with positive ANCA: atypicalpresentation of Wegener's disease orlymphocytic hypophysitis?F Medici & P KellyIsolated secondary hypothyroidism in identicaltwinsPJ Weston, AK Annamalai & S BandyopadhyayAdrenal-insufficiency manifesting ashyperkalaemic paralysisAS Kashyap, KP Anand & S KashyapHypercalcaemia and hypereosinophilicsyndrome in a patient withcholangiocarcinomaKP Papatheodorou, DP Papazoglou, NP Papanas,CI Iakovidis & EM MaltezosP113P114P115P116Mineral-rich baths - an unusual source ofexposure to excess iodineKD Hopkins & S IbrahimBiochemical screening <strong>for</strong> RET negativemedullary thyroid carcinoma (MTC): a casereport highlighting difficulties in theinterpretation of pentagastrin stimulatedcalcitonin testingDR Webb, N Seevaratnam, M Suri & P KingA long-standing lump in the neck provingtroublesome <strong>for</strong> the surgeonsS Bandyopadhyay & JP VoraA case of isolated ACTH deficiency whodeveloped autoimmune-mediatedhypothyroidism and hepatitisSY Kim, JH Kim & HY BaeP103P104Di-George syndrome presenting withhypocalcaemia and personality disorder inadulthood - a case reportM Jose, N Iqbal, P Gaut, D Balakrishnan &H MaksoudPhaeochromocytoma presenting as gestationaldiabetesKM Evans, I Montague, BA Millward & DE FlanaganP117P118Cushing's disease presenting as aschizophreni<strong>for</strong>m psychosisRW McCallum, V Parameswaran, A Duffield,L Hoffman, JR Burgess & T GreenawayObesity, hypertension and elevatedcatecholaminesAA Joshi, VKB Prabhakar, HD White, MJ Diver &JP VoraPOSTERSP105P106P107P108P109P110P111Conn's syndrome associated withhyperprolactinaemia: two case reports.Hypertension was cured by surgery in bothcases despite a 10- and 16-year historyI Talapatra, S Ghosh & DJ TymmsParathyroid carcinoma in multiple endocrineneoplasia (MEN) type 1: two case reportsA Agha, R Carpenter, S Bhattacharya & JP MonsonCo-existing hypoparathyroidism and vitamin Ddeficiency causing life-threateninghypocalcaemiaL Edwards & M AbubakerA rare case of metastatic choroidal melanomato the thyroid gland: the importance ofcytologyC Vezzosi, C La Magra, P Pedaccini, M Bernardini,S Silvestri & R NassiA complex case of pregnancy andpegvisamont treated acromegalyAI Qureshi, G Ramanathan, A Walton, L Seal,G Bano, I Manyonda & A PanahlooPost-partum thyroiditis (PPT): colour-Dopplerultrasonography evaluationP De Remigis, A De Remigis & L VianaleThe challenges of managing metabolicderangementsN Iqbal, A Gruber & G ThomsonP119P120P121P122P123P124P125P126P127Cushing's syndrome in an adolescent withMEN1: where is the lesion?F Smeeton, JS Davies, MF Scanlon & DA ReesGlucagonoma: does the clinical expressiondepend on the presence of inherited disease?F Smeeton, JS Davies, MF Scanlon & DA ReesA rare cause of gynaecomastiaC Ravikumar, M-F Kong, MJ Levy & TA HowlettIs the continuation of lithium treatment safeduring peri-operative periods?A Tan, S Bandyopadhyay & JP VoraAn unusual cause of jaundicePJD Owen, SS Lakra, LDKE Premawardhana,A Baghomian, A Godkin & JH LazarusSevere thyrotoxicosis and pregnancyJH Parr, A James Jones, K Wynne & S WahidIdentification of two novel GALNT3 mutationsin a patient with familial tumoral calcinosis(FTC)AM Barbieri, M Filopanti, G Bua & P Beck-PeccozMegadenomaBCT Field, SC Barnes, MJ Wheeler, MP Powell,SM Thomas & PV CarrollAutoimmune hypophysitis causing permanentdiabetes insipidus - a case reportD Grant, K Campbell & J Connell34www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P128P129P130P131P132P133P134P135P136P137P138P139P140P141P142Time course of neuroendocrine dysfunctionafter aneurysmal subarachnoid hemorrhage -need <strong>for</strong> reassessment even years after thehemorrhage?A Reineke, E Poll, S Levasseur, E Yagmur,JM Gilsbach & I Kreitschmann-AndermahrA case of late onset congenital adrenalhyperplasia in a female epileptic patient:implications <strong>for</strong> clinical practiceE Davies, J Kisalu, PM Bouloux & M ThomasAdult-onset nesidioblastosis- a rare clinical caseT Martins, L Gomes, J Guimarães, M Melo &M CarvalheiroSeeking an appropriate sex of rearing in5α-reductase deficiencyS Iyer, RM Thomas & T Cheetham49,XXXXY syndrome connected withhypothyroidismB Wikiera, R Slezak, E Glab, E Barg & A NoczynskaGiant labia majora in familial partiallipodystrophyT Kyaw Tun, N Correia, NA Phelan, M Shahid,O Buckley, W Prendeville & J GibneyPituitary apoplexy and acromegaly: a casereportK Jacob, J Sudagani, S Anwar, C Gibson, FCW Wu,DW Ray & JRE DavisThe effects of lanreotide administration vsunilateral adrenalectomy on disease activity inGIP-dependent Cushing's syndromeM Robaczyk, B Krzyzanowska-Swiniarska, G Kulig &K PilarskaEpilepsy at presentation of macroprolactinomaD Deepak, N Bashir, P Foy & IA MacFarlaneDifficulty to distinguish hyperandrogenia dueto a tumoral <strong>for</strong>mation or to polycystic ovarysyndrome: a case reportMP Teissier, C Combes, A Drutel & S LopezResolution of diagnostic uncertainties withDAX-1 gene mutation analysisP Arundel, R Fisher, C Chu & S AlviMultihormonal disorders in 17-year-old girlwith congenital hypoplastic anemia andsecondary hemochromatosisE Glab, B Wikiera & E BargCarcinoid tumour: spontaneous regressionfollowing pregnancyEL Lim, I Macleod, D Carr, D Manas, R Quinton &A JamesA rare cause of thyrotoxicosis andhypercalcemiaNPN Murthy, Y Prasad, M Thomas & T FiadMaternal virilization and female fetalpseudohermaphroditism caused byexaggerating androgen secretion ofpregnancy leutomasC Chen & Y WangP143P144P145P146P147P148P149P150P151P152P153P154P155P156P157Two unusual cases of extra-adrenalphaeochromocytomaPK Singh, N Iqbal, P Strouhal, BM Singh &HN BuchProlonged hungry bone syndrome in a patientwith Wolfram syndrome: a case reportO Basat, S Ucak, AB Oncul, S Seber, N Eren &Y AltuntasPostmenopausal androgen excess: a clinicalperspectiveSA Ritchie, A Collier, M McIntyre & JMC ConnellUse of pulse methylprednisolone therapy inGraves' ophthalmopathyO Nechaeva, Y Bardeeva, O Perepelova,T Shestakova & I ChikhAcute suprarenal impairment because of anadrenal bilateral necrosis withantiphospholipids' syndromeJ Combes, S Chabroux & JP OryChallenges in the management of anuncommon cause of diabetes insipidusK Kaushal, K Jacob & SM ShaletPsychiatric and movement disorders inprimary hypoparathyroidismS ChatterjeeA case report of malignant insulinomaN Jeandidier, S Boullu, L Ciarloni, S Drui, B Louis,M Pinget, JE Kurtz & G ChabrierMalignant paraganglioma in young patientwithout symptoms - a case reportZ Velija-AsimiSecondary amenorrhoea induced bydihydrocodeine ingestion resolves followingopiate withdrawalS González & RD MurrayCombined cortisol and aldosteronehypersecretion in two unusual cases ofhypertension due to adrenocortical neoplasiaSCM Miller & JMC ConnellEndocrine disorders in a high secure hospitalIA MacFarlane, D Deepak & GV GillAcromegaly with a double pituitary adenomaS Chandran & C Parkinson17β-Hydroxysteroid dehydrogenase deficiencycaused by homozygous H271R mutationA Bachelot, Z Chakhtoura, F Kuttenn, Y Morel &PH TouraineSmall intragenic somatic mutation associatedwith a germline mutation of HRPT2 gene in apatient with sporadic primaryhyperparathyroidismE Pardi, F Cetani, E Ambrogini, S Borsari, M Lemmi,A Pinchera & C Marcocciwww.ece2006.com 35POSTERS
8th European Congress of <strong>Endocrinology</strong>P158Plasma exchange <strong>for</strong> the prevention of severethyrotoxic exacerbation following radioactiveiodine therapy <strong>for</strong> Graves' hyperthyroidismA Wee, V DeSilva & MG PrenticeP172Addison's disease: soy sauce - a life-savingconcoctionB Bhattacharya, A Ullah, WSA Smellie, A McCulloch& AH HealdPretibial myxoedema: is this a marker <strong>for</strong>occult thyroid ophthalmopathy?B Bhattacharya, A Ullah, AJ McCulloch & AH HealdP159Not-so-silent, silent corticotroph adenomasSGI Suliman, SE Baldeweg, O Ansorge, A Clark,M Powell & JAH WassP173POSTERSP160P161P162P163P164P165P166P167P168P169P170P171Cushing's syndrome presenting withpalpitationsNG LessanAn unusual case of PTHrPoma with coexistentsecondary hyperparathyroidismMO Sharfi, E Hardy, AA Panahloo, F Lofts & LJ SealFalse positive newborn screen <strong>for</strong> congenitalhypothyroidism due to a TSH-IgG (macro-TSH)complexDJ Halsall, SK Hall, P Barker, J Anderson,M Fahie-Wilson, R Gama & VK ChatterjeeFamilial hypocalciuric hypercalcemia (FHH)caused by P748L mutation in the calciumsensing receptor (CaSR) geneR Mahto, A Tahrani, A Macleod & RV ThakkerImportance of complex evaluation of thechanges in ST-segment in ECG: case report ofthe patient with Addison disease and BrugadasyndromeM Pura & P VanugaMet<strong>for</strong>min-associated lactic acidosis in aCaucasian woman precipitated by acute renalfailure treated with bicarbonate haemodialysisT González Losada, L Del Olmo García, P Martinezde Icaya, V Alcázar Lázaro, T López del Val,M Pérez Pelayo & S Herranz AntolínDysgerminoma and gonadoblastoma inchildren with complete androgen insensibilityA Noczynska, T Zak & B SalmonowiczUnexpected features in Prader-Willi syndrome- case reportC Vulpoi, C Rusu, MC Ungureanu, C Preda,O Stoica & E ZbrancaThree extreme cases of electrolyte imbalanceinducedseizuresAG Gruber, N Iqbal & GA ThomsonTwo cases of idiopathic primaryhypoparathyroidismC Badiu, D Cristo<strong>for</strong> & M CoculescuCushing's syndrome due to medullary thyroidcarcinoma - a case reportA Sousa, E Rodrigues, A Varela, E Vinha, D Braga,P Couto, J Lopes, M Cardoso-Oliveira & JL MedinaPolymyalgia rheumatica and HashimotothyroiditisGN Karachalios, I Kostoglou-Athanassiou,P Athanassiou & PH KaldrymidisP174An unusual carcinoid tumor in a case ofCushing syndromeZT Turki, FA Aouididi, HS Smida, LBS Ben Salem,RB Bouguerra & CBS Ben SlamaClinical practice and governanceP175P176P177P178P179P180P181P182P183Audit on management of chronic adrenalinsufficiencyRK Rao, A Brahma & H GraySalivary cortisol daycurve and quality of lifeassessment in optimizing glucocorticoidreplacement therapy in patients withAddison's diseaseLCCJ Smans, EGWM Lentjes & PMJ ZelissenSymptom-specific thresholds <strong>for</strong> testosteronedeficiency modulate complaints and metabolicrisk in 434 aging male patientsM Zitzmann, S Faber & E NieschlagLong-term experience of more than 8 yearswith a novel <strong>for</strong>mulation of testosteroneundecanoate (nebido) in substitution therapyof hypogonadal menM Zitzmann, F Saad & E NieschlagImprovements <strong>for</strong> patients and nurses using2.5ml prefilled syringes as the vehicle solution<strong>for</strong> suspension of sandostatin LARmicrospheresKT Maher, WM Drake, GM Besser, AB Grossman,SL Chew, PJ Jenkins, LA Kalingag, FK Fode,MT O'Sullivan-Hawketts, DM Walker & JP MonsonImpaired thirst and AVP release in a patientwith partial cranial diabetes insipidus (CDI)and subtle pituitary diseaseWHMS Chandrasekara, S Khan, SS Lakra,MD Penney & LDKE PremawardhanaReactive hypoglycaemia - can measuringinsulin concentrations help understand thepathophysiology and support diagnosis?RB Poole, AJ Brooks & JSW Li Voon ChongImpaired quality of life in patients with adrenalinsufficiency - evidence that improvedglucocorticoid replacement strategies areneededS Hahner, M Loeffler, W Arlt, O Decker, ACKoschker, D Weismann, M Fassnacht & B AllolioLong-acting, intramuscular testosteroneundecanoate (TU, NEBIDO) in the treatmentof female-to-male transgender individualsJW Jaobeit, M Epe, U Hugo, M Ludwig &HM Schulte36www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P184P185P186P187P188P189Long-acting intramuscular testosteroneundecanoate (TU, NEBIDO) in treatment ofhypogonadal aging malesJW Jacobeit & HM SchulteScreening in primary care using fastingglucose uncovers significant hypoglycaemiaincluding an asymptomatic insulinomaS Wordsworth, M Hassanein & J PlattsComparison of the effect of sibutraminemonotherapy with sibutramine-met<strong>for</strong>mincombination therapy in nondiabetic obesewomenM Sargin, H Sargin, H Gozu, M Tuna, F Erkal,M Tekce & A YaylaTorbay adrenal and pituitary projectS CoxAutoimmune hypoadrenalism: the profile ofrelated conditionsJAH Wass, KG White & A ElliottRecombinant hGH therapy in males withorganic GHD: should we trust in totaltestosterone levels <strong>for</strong> diagnosis of centralhypogonadism?C Giavoli, AG Lania, E Ferrante, F Ermetici,S Bergamaschi, CL Ronchi, B Ambrosi, A Spada &P Beck-PeccozP190 Survey of steroid replacement therapyS Gorick, RH Greenwood, PJ Heyburn, MJ Sampson,KK Dhatariya & RC TempleP191 Concordance between GH determination andIGF-I in acromegaly using two IGF-I methodsS Hepburn, SM Chambers, JA Gilbert,AM McGregor, JP Miell & SJB AylwinP192 Adult Turner syndrome clinic: what are thepatients' perceptions of this specialist service?LE SmethurstP193 Adequacy of post-glucose GH nadir 20 000mU/l -review of presentation, management andoutcomeN Seevaratnam, E Khoo, R Rea & P MansellP195P196P197Long term outcome in men withmicroprolactinomaR Rea & W JeffcoateOphthalmic findings in Turner syndromeB Wikiera, M Mulak, E Barg & B ReniewskaEarly detection of diabetic autonomicneuropathy with a new deviceM Fevre-Genoulaz, MJ Lafitte, SS Srikanta,L Punitha & S VidyanandP198P199P200P201P202P203P204P205P206P207P208P209P210Adult growth hormone replacement therapyafter the institution of NICE guidelinesS Curran, P Lowdell, A Webb, C Holmes, M Gurnell,DF Wood, VKK Chatterjee & HL SimpsonClinical evaluation of Sheehan syndromeA Kubat Uzum, M Mert, Y Orhan, N Ozbey &F AralIs a repeat or resting prolactin necessary in theinvestigation of hyperprolactinaemia?R Agarwal, S Pramodh, P Durroch, S Chambers,A McGregor & SJB AylwinKnowledge of testosterone replacementtherapy is significantly correlated with patientsatisfaction, suggesting greater need <strong>for</strong>educationSV Llahana & GS ConwayCushing's disease - an audit of outcomesfollowing pituitary surgery from a singlecentreV Baskar, G Varugheese, V Carlin & RN ClaytonClinical characterization of patients withhyperprolactinaemia due to macroprolactinF Donadio, AR Angioni, A Lania, E Orsi,P Beck-Peccoz & A SpadaTotal cortisol and calculated free cortisolduring the 250µg ACTH testM Klose, M Lange, A Krogh-Rasmussen, E Haug &U Feldt-RasmussenComparison of the effects of transdermal andoral oestrogen treatments on serum andsalivary cortisol concentrationsA Bahri, L Breen, S Barnes, JK Powrie, SM Thomas &PV CarrollA survey of gender dysphoria (transsexual)patients attending an endocrine clinicG Scull, C Gibson, L Webster, DW Ray, FCW Wu &JRE DavisOsteoporosis, osteopaenia and osteoarthritis inautoimmune hypoadrenalismJAH Wass, KG White & A ElliottAutoimmune hypoadrenalism: symptoms atdiagnosisKG White, JAH Wass & A ElliottDoes HT still have a place? The impact onmenopausal-related symptomsC Cristea, C Vulpoi, MC Ungureanu, L Leustean,C Concita, V Mogos & E ZbrancaHigh mortality rate in hospital in-patients withhyponatraemiaLCH Ciin, P Narayanan, F Stewart, A Heald &T Dornanwww.ece2006.com 37POSTERS
8th European Congress of <strong>Endocrinology</strong>Comparative endocrinologyP211The patients with HIV lipodystrophy syndromehave lower total fat mass but similar free fatmassP Freitas, D Carvalho, F Correia, T Faria, B Perez,R Marques, R Serrão, J Pereira, A Mota Miranda &JL MedinaP223P224Low dose dexamethasone does not alterserum adiponectin or resistin concentrationsKC Lewandowski, K Szosland & A LewinskiInterleukin-6 and TNF-alpha in hemodialysispatients: association with obesity andmetabolic syndromeZ Rasic, G Perunicic, Z Gluvic, J Tica & M PavicevicP212Dynamic macroprolactin and adjustedprolactin responses in hyperprolactinaemicpatientsS Bandyopadhyay, MJ Diver & JP VoraP225VEGF and sVCAM in patients with adrenalgland tumorsTA Britvin, NE Kushlinsky, IA Kazantseva,MA Sivtsova & AP KalininP213P214Retrospective study of usefulness of Sestamibiscans in primary hyperparathyroidismK John, S Blackburn, J Miell & C DiazAssessment of oxidative stress in patients withpolycystic ovarian syndrome treated witheither orlistat or met<strong>for</strong>minJ Shepherd, V Jayagopal, ES Kilpatrick & SL AtkinPrognostication in canine parvoviral diarrhoeausing basal serum cortisol concentrationsJP Schoeman, LJ Venter, A Goddard, AL Leisewitz &ME HerrtageP226P227Prolactin deficiency is independentlyassociated with reduced IGF-I status inseverely GHD adultsA Mukherjee, WDJ Ryder, A Jostel & SM ShaletGH/IGF-I axis and haematological alterationsin anorexia nervosaN Polli & F CavagniniSelected hormones serum levels independence on BMI and sexM Tajtáková, Z Semanová, D Petrás˘ová,J Petrovičová & M PytliakP215P228P216Short-term effects of propionate on the leptinsystem and on G protein-coupled receptorGPR41 mRNA levels in adipose tissue of goatsMM Mielenz, CS Seybold & HS SauerweinP229Abnormalities of humoral immunity withreduced immunogenicity to pneumococcalvaccine in panhypopituitarismA Mukherjee, M Helbert, JRE Davis & SM ShaletLack of influence of an IGF-I genepolymorphism on circulating IGF-I levels inseverely GHD adultsJAMJL Janssen, A Mukherjee, HK Gleeson,S Lamberts & SM ShaletSerum TGF-beta-1 levels in non-alcoholicsteatohepatitisS Yener, B Akinci, F Bayraktar, T Demir, M Akarsu,MA Özcan, M Yalcin, L Kebapcilar, A Comlekci &S YesilP217Ontogeny of galanin and vasotocinimmunoreactivity in the supraoptic nucleus(SON) and the bed nucleus of the striaterminalis (BSTM) in chickensS Klein & R GrossmannP230POSTERSCytokines and growth factorsP218 The role of IL-4 and IFN-gamma as prognosticfactors of major adverse cardiac events inpatients with ST-elevation myocardialinfarction assigned primary percutaneouscoronary interventionM Osuch, B Szygula-Jurkiewicz, J Szkodzinski,R Wojnicz, A Lekston, L Polonski, A Blazelonis &B Zubelewicz-SzkodzinskaP219 Adiponectin and resistin concentrations duringoral glucose tolerance test (OGTT) in insulinresistantsubjectsK Szosland, K Lewandowski, H Randeva &A LewinskiP220 Effects of IGF-II on glucose metabolismS Zachariah, A Brackenbridge & D Russell JonesP221 Interleukin-6 and trans<strong>for</strong>ming growth factorbeta-1 concentration in serum in patients withcoronary vessels restenosisAB Blazelonis, J Szkodzinski, W Romanowski,A Danikiewicz, M Gasior, L Polonski, A Kaszuba,M Muc-Wierzgon & B Zubelewicz-SzkodzinskaP222 Immunosuppressive effect of recombinanthuman erythropoietinA Vahdati, M Adib & S KashfiP231P232P233P234P235Subclinical hypothyroidism could be regardedas a benign condition in oxidative stress butnot in atherosclerosisL Kebapcilar, B Akinci, F Bayraktar, A Comlekci,A Solak, T Demir, S Yener, T Kume, A Ozkaya &S YesilLow TGF-beta-1 levels in idiopathic maleosteoporosisB Akinci, F Bayraktar, A Saklamaz, T Demir, S Yener,A Comlekci, MA Ozcan, L Kebapcilar, F Yuksel &S YesilPossible predictive value of IGF-II mRNAexpression in breast cancer (BC)CG Giani, EG Giustarini, PF Fierabracci, DCCampani & MEL LippmanIGF-II protein expression in breast cancer.Relationship with the most importantpredictive parameters in breast malignancyEG Giustarini, AP Pinchera, DC Campani,PF Fierabracci, KC Cullen & CG Giani38www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P236P237P238P239P240P241P242P243P244P245P246The effect of growth hormone replacement onthe diurnal and ultradian dynamics of ghrelinand leptin in adult growth hormone deficiencyF Joseph, G Brabant, A Ahmad, B Durham,WD Fraser & JP VoraGrowth hormone receptor extracellulardomain linked to glycophosphatidyl inositol(GHR-GPI); a potential growth hormonereceptor antagonistCE Bowles, I Wilkinson, N Gavalas, P Watson,D Watts & R RossThe depot specific expression of NPY inhuman adipose tissue and its upregulationunder hyperinsulinaemic conditions in isolatedhuman adipocytesK Kos, AL Harte, P Gupta, P O'Hare, PG McTernan& S KumarThe role of BMPs in the establishment of zonaglomerulosa in the adrenal glandA Bakmanidis & PJ KingAnosmin-1: a novel cofactor <strong>for</strong> fibroblastgrowth factor receptor-1Y Hu, S Kim, S Cadman, S Guimond, J Turnbull &P BoulouxEffect of growth hormone deficiency in adultson insulin action and gene expression ofselected adipokines in subcutaneous adiposetissueA Penesova, M Skopkova, M Pura, M Vlcek,Z Radikova, I Vorzakova, M Tajtakova, P Vanuga,V Belan, J Koska, J Payer, I Klimes & D GasperikovaSoluble interleukin 2 receptor is elevated insera of women with Graves' disease and hasrelation to serum free thyroxine and thyroidvolumeJ Jiskra, M Antosova, E Potlukova, Z Lacinova,H Mareckova, P Sandova, D Smutek & Z LimanovaMolecular mechanisms of idiopathic musclehypertrophy in humansAM Solomon, EP Hoffman, SD Ghimbovschi,Z Wang, RW Orrell, G Goldspink, SD Harridge &PMG BoulouxCD4 T-cell count improves during sustainedIGF-I response following low dose growthhormone therapy in HIV-infected patients onstable antiretroviral regimens. A pilot studyO Andersen, BR Hansen, A Flyvbjerg, S Madsbad,H Ørskov, JO Nielsen, J Iversen & SB HaugaardThe differential influence of specific plantlectins on insulin and IGFs binding tosolubilised placental membrane IGF andinsulin receptorsR Masnikosa, I Baricevic & O NedicGH and GH antagonist B2036 effect on theimmune systemM Maamra, F Perna, A Colao, R Pivonello,S Zappacosta, RJM Ross & G MatareseP247P248P249P250IGF-I modulates HIF-1alpha and HIF-2alpha inKaposi sarcomaSB Catrina, IR Botusan, A Rantanen, AI Catrina,P Pyakurel, M Axelson, P Biberfeld, L Poellinger &K BrismarProinflammatory cytokine gene expressionshows intrinsic circadian oscillation inperipheral cellsA McMaster, J Lebiecki, A Loudon, R Donn &DW RayPlasma interleukin 1α in patients withpolycystic ovary syndrome - relation to insulinresistanceI Kowalska, M Straczkowski, A Nikolajuk,A Kozlowska, M Karczewska-Kupczewska,A Adamska, S Wolczynski, I Kinalska & M GorskaExpression of functional toll-like receptors inadipocytesKM Oeff & SR BornsteinDiabetes, metabolism and cardiovascularP251 The involvement of GH-IGF-I axis in a mousemodel of type II diabetic nephropathyR Eshet, D Landau, L Wachsmann & Y SegevP252 Sodium bicarbonate reacts withpolysaccharides, starch, to enhance exerciseTSM ArbabP253 New function <strong>for</strong> the enzyme amylasediscovered. Amylase works as acatalyst/hydrolyzing agent to break downdisaccharides (sucrose, lactose, maltose etc),and polysaccharides (starch)TSM ArbabP254 Liver GH receptor signaling in type I diabeticmiceL Wachsman, R Eshet, D Landau & Y SegevP255 The effects of changes in insulin sensitivity onandrogen supply values in diabetic men atdifferent ageMD Tronko & OV Korpacheva-ZinychP256 The effect, in clinical practice, of long-actingfluvastatin (LAF) on low density lipoproteincholesterol(LDL-Ch) in patients with type 2diabetes mellitus (T2DM) in which otherstatins have failed to achieve the goalsFJ del Cañizo-GómezP257 Nutritional outcome in end-stage renal diseasediabetic patients: short term follow-up ofpatients initiating/escaping dialysisC Raffaitin, P Chauveau, C Lasseur, N Barthe,H Gin, C Combe, JB Corcuff & V RigalleauP258 Improvement of nutritional status in nondialyseduremic diabetic patientsC Raffaitin, P Chauveau, C Lasseur, N Barthe,H Gin, C Combe, JB Corcuff & V Rigalleauwww.ece2006.com 39POSTERS
8th European Congress of <strong>Endocrinology</strong>P259P260Subthalamic nucleus stimulation inParkinsonian patients does not increase serumghrelin levelsJB Corcuff, C Perlemoine, F Macia, F Tison, I Coman,D Guehl, P Burbaud, E Cuny, L Baillet, H Gin &V RigalleauHyperandrogenism as a risk factor of coronaryartery disease in young womenZ Sablik, A Samborska-Sablik, JH Goch & K KulaP271P272AT1 receptor activation mediated oxidativestress and uncoupling protein-2 driven betacelldysfunction in obesity-induced type 2diabetes mellitusKY Chu & PS LeungEffects of hyperglycemia on the AT1 receptorexpression and secretory function in an INS-1Ebeta-cell linePS Leung, KK Leung & KY ChuEvaluation of garlic extract effect on serumangiotensin converting enzyme (ACE) level instreptozotocin-diabetic ratsSM Shafiee, SM Hosseini, A Yabesi & ZB HesabiP261 Comparison of urinary N-acytylβ-D-glucoseaminidase activity in diabeticpatients and controlsZB Hesabi & S SalimiP262 Association of hypogonadism and type 2diabetes in men attending an outpatienterectile dysfunction clinicG Corona, E Mannucci, L Petrone, R Mansani,G Balercia, R Giommi, V Chiarini, G Forti &M MaggiP263 Estimation of the lipid metabolism in womenwith gestational diabetes mellitus (part 2).Differences resulting from the method oftreatmentA Bronisz, M Sobis-Zmudzinska, M Pujanek &R JunikP264 Estimation of some parameters of lipidmetabolism in pregnant women withgestational diabetes mellitusM Sobis-Zmudzinska, A Bronisz, M Pujanek &R JunikP265 The role of a lifestyle modification inpreventing type II diabetes mellitus in subjectswith high-risk factorsEI Shishko & TV MokhortP266 The effect of Greek mediterranean diet ontrace elements and blood coagulation factorsin type 2 diabetes patientsA Ginis, C Tzioras, N Panayotou & C PhenekosP267 12-month audit of insulin glargine use in thediabetic clinicD Ghosh & M ElsheikhP273POSTERSP268P269P270Increased expression of the adipokines resistinand FIAF in hypoxic/ischemic mouse brainG Wiesner, RE Brown, GS Robertson, E Ur &M WilkinsonPrevalence of chronic cardiovascularcomplications in newly diagnosed type 2diabetic patientsD Metreveli, N Bibilashvili, I Gudushauri,N Gambashidze, Z Robitashvili, K Mikadze,L Tigishvili & C SajaiaHormonal profile associated with the insulinsensitive obese subjectsDH St-Pierre, AK Karelis, JF Henry, FM Malita,J Fontaine, D Mignault, M Brochu, JP Bastard,E Doucet, K Cianflone & R Rabasa-LhoretP274P275P276P277P278P279P280P281P282P283Determinants of metabolic syndrome andinsulin resistance in hemodialysis patientsHC Chen & JY GuhHyperlactatidemia caused by acute myocardialinfarction in patients with type 2 diabetesmellitusA Jovanovic, V Peric, S Sovtic, T Novakovic, R Stolic& S Markovic-JovanovicThe safety and efficacy of chinese herbalmedicine PHS-E2 (Glucoherb) instreptozotocin-induced diabetic Wistar ratsTA Elhadd, AA Al-Amoudi, SMG Al-Ghamdi,E M Ibrahim & HA El-ShiekhEducation <strong>for</strong> diabetic patients <strong>for</strong> fasting ofRamadan: a questionnaire studyAA Al-Amoudi, N Al-Ulagi, M Bashir, L Bissar,SMG Al-Ghamdi & TA ElhaddAlcohol intake deteriorates insulin receptorsand adipokines expression in rat adipose tissueE Pravdová, M Ficková & L MachoDes-acyl ghrelin regulates glucose and lipidmetabolism in HL-1 cardiomyocytesMJ Iglesias, R Piñeiro, S Eiras, B Rodiño,JR González-Juanatey & MF LagoRegulation of brain-derived resistin and FIAF ina novel hypothalamic neuronal cell lineRE Brown, A Imran, DD Belsham, E Ur &M WilkinsonMyocardial ischemia in type 1 diabeticpatients - re-examination after four yearsM Kowalczyk, B Chrapko, J Zaorska-Rajca,JS Tarach & A NowakowskiThe metabolic syndrome presence inperipheral arterial occlusive disease of diabeticpatientsDS Tesic, P Pantelinac, M Mitrovic, R Pejin,J Radosavljevic, D Naglic, D Tomic & I ObrovackiA TCF1 mutation may cause transientcongenital hyperinsulinism followed byMODY3K Brusgaard, HBT Christesen, T Hansen, P Njölstad,J Malec & B Brock Jacobsen40www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P284P285P286P287P288P289P290P291P292P293P294P295Waist circumference cut-offs <strong>for</strong> categorisationamong Tunisian adult populationR Bouguerra, H Smida, L Ben Salem, J El Ati,S Gaigi, CH Ben Rayana, C Ben Slama & B ZouariAssociations between BMI and smoking withreference to other life style factors, the 4thand the 5th Tromsø studiesM Sneve & R JordeGene variants at calpain-5 locus are associatedwith obesity and other features of metabolicsyndromeME Saez, MT Martinez-Larrad, R Ramirez-Lorca,JL Gonzalez-Sanchez, C Zabena, A Gonzalez,A Ruiz & M Serrano-RiosPlasma concentrations of asymmetric dimethylarginine and total homocysteine in siblings oftype 2 diabetes mellitusS Guldiken, CH Karadag, E Arikan, M Demir &M KaraMortality risks of diabetic patients who reachend-stage renal disease (ESRD) in the UnitedStates: age and gender differencesAG Stack & L O'SheaHormonal profile in men suffering fromcoronary artery disease and metabolicsyndromeZ Sablik, A Samborska-Sablik, JH Goch & K KulaThe impact of vitamins and/or mineralsupplementation on blood pressure in type 2diabetesM Farvid, M Jalali & F SiassiPro12Ala PPAR gamma2 gene polymorphismin PCOS women - the role of the satiety andinsulin activity regulating compoundsB Bidzinska-Speichert, U Tworowska, M Demissie,G Bednarek-Tupikowska & R SlezakGlucose metabolism, insulin secretion andinsulin sensitivity in juvenile hemochromatosisN Angelopoulos, M Noutsou, A Goula & G TolisGlucocorticoids are metabolised withinperivascular adipose: the link betweenmetabolic diseases and their vascularconsequences?AR Dover, CJ Huang, DE Livingstone,PJ Raubenheimer, PWF Hadoke, BR Walker &RM ReynoldsAbsence of sexual dimorphism in thesymptomatic responses to hypoglycaemia inadults with and without type 1 diabetesJ Geddes, RE Warren, AJ Sommerfield, V McAulay,MWJ Strachan, KV Allen, IJ Deary & BM FrierMetabolic syndrome and insulin sensitivity inearly glycoregulation disordersV Dimitrijevic-Sreckovic, P Djordjevic, S Popovic,D Gostiljac, F Canovic, B Sreckovic, M Ilic,T Novakovic, E Colak, R Obrenovic, G Milic, T Nisic& V PanasiukP296P297P298P299P300P301P302P303P304P305Biochemical predictors of the cardiovascularcomplications in patients with obesity andtype 2 diabetesT Doliashvili, E Giorgadze, N Tsagareli, K Asatiani &K BochorishviliDecreased cardiac and arterial noradrenalineand dopamine concentrations occurconcomitantly with the development of type IIdiabetes in rats treated neonatally withmonosodium glutamate (MSG): a possiblebasis <strong>for</strong> autonomic neuropathy?JFB Morrison, M Shaffiullah, S Dhanasekaran,R Sheen & EK Mensah-BrownGender distribution in Ukrainian adult insulintreateddiabetics depending on age atdiagnosisM Tronko, M Khalangot, V Kravcenko, Y Kulchinska& A VaisermanEffects of arm exercise on metabolicparameters in type 2 diabetic patientsN Leelayuwat, O Tunkumnerdthai, M Donsom,N Punyaek, T Pratipanawatr & U KukongviriyapanThe ethanolic extract of Combretumdecandrum Roxb. improved glucose toleranceand increased glucose uptake ofhyperinsulinemic ratsP Pannangpetch, W Theansuwan, B Kongyingyoes,V Kukongviriyapan & U KukongviriyapanIn-patients food intake and reasons of nonconsumptionB Gatta, D Daniel-Lamazière, J-B Corcuff, F Poirier,M-N Petitpierre, F Morizot & H GinRenal expression of alpha-ENaC is increased intestosterone treated ratsT Kienitz, B Allolio, CJ Strasburger & M QuinklerInsulin resistance syndrome and non-alcoholicfatty liver disease in obese children: influenceof ethnic background, sex, age and familyhistory of type 2 diabetesDL Clough, L Watson, C Cuisick, L Tetlow, RA Amin,PE Clayton & CM HallSerum ghrelin levels during oral glucosechallenge - new insights from gastrectomizedpatientsD Miljic, S Pekic, P Pesko, M Djurovic, M Doknic,J Glodic, C Dieguez, FF Casanueva & V PopovicA gene-gene interaction of single nucleotidepolymorphisms within two oxidative stressgenes affects arterial compliance in patientswith coronary artery diseaseRS Drummond, HHC Koh-Tan, NJR Brain,JD McClure, LM Cherry, AJB Kirk, N Sattar,JMC Connell & AF Dominiczakwww.ece2006.com 41POSTERS
8th European Congress of <strong>Endocrinology</strong>P306P307The variable number of tandem repeatpolymorphism in the NOS3 gene is associatedwith arterial compliance and insulin resistancein coronary artery diseaseRS Drummond, HHC Koh-Tan, NJR Brain, A Kirk,N Sattar, JMC Connell & AF DominiczakAltered cholesterol and bile acid homeostasisin the hexose-6-phosphate dehydrogenase(H6PDH) knockout mouseKN Hewitt, IJ Bujalska, GG Lavery, PM Stewart &EA WalkerInsulin secretion in HBV and HCV infectedpatients with type 2 diabetes mellitusLY Hamnueva, LS Andreeva & AV DavydovaP318P319Cardiovascular risk factors and macrovascularcomplications in type 2 diabetesK Khiari, H Cheikhrouhou, I Hadj Ali &N Ben AbdallahEffects of ezetimibe on serum lipoproteins inpatients with homozygous familialhypercholesterolemia undergoing LDLcholesterol apheresis and high doseatorvastatin therapyA Azezli, T Bayraktaroglu, F Kutluturk, A Cikim,S Tanyolac & Y OrhanEffect of micronised fenofibrate on plasmalevels of C-reactive protein in combinedhyperlipidemiaA Azezli, T Bayraktaroglu, F Kutluturk, A Cikim,S Tanyolac & Y OrhanLong term safety of atorvastatin andfenofibrate therapy in patients with combinedhyperlipidemiaA Azezli, A Telci, T Bayraktaroglu, A Cikim, A Uzum,F Kutluturk, S Tanyolac & Y OrhanUse of insulin glargine during pregnancy inwomen with type 1 diabetes mellitusD Ghosh, D Graham, P Street & M ElsheikhP308P309P310P311The pancreatic beta-cells autoantibodies inHBV and HCV infected patients with type 2diabetes mellitusAV Davydova, LY Hamnueva & LS AndreevaAdrenomedullin increases the expression ofCLR and RAMP2 in microvascular endothelialcellsN Schwarz, K Sidhu, S Kapas & JP HinsonSympathetic function in carriers of MC4RmutationsD Heutling, F Sayk, C Dodt, HL Fehm, T Frank,A Hinney, J Hebebrand & H LehnertP320P321P322P323Serum ferritin levels and obesityF Kutluturk, A Sertkaya Cikim, A Azezli & Y OrhanP312P313P314A case of myocardial infarction induced byfactitious hypoglycaemia in type 2 diabetespatientR Srinivasan, E Sanders & M FlynnOrlistat improves postprandial triglyceridemetabolism in obese patients with or withoutdiabetesI Sahin, R Bentli, L Keskin, C Taskapan, S Senel &S YologluChallenge in achieving target HbA1c in arelatively rare diabetes complicationMU Haq, G Morrison & PJ WestonDepot specific activation of inflammatorysignalling molecules JNK and NFκB in humanabdominal subcutaneous and omental adiposetissueNF da Silva, AE Fowler, AL Harte, AR Baker,CM Kusminski, SJ Creely, P O'Hare, S Kumar &PG McTernanP324P325P326Utility of continuous glucose monitoring(CGMS) to explore glycemic patterns inpatients with diabetes mellitus in the UAENG Lessan, A Abdullah, H AlMousavi, Q Nasir &S AthamnehDyslipidemia in premenopausal andpostmenopausal obese womenA Sertkaya Cikim, F Kutluturk, A Azezli & Y OrhanThe effect of moxonodine on endothelialdysfunction in metabolic syndromeA Sertkaya Cikim, E Topal, K Cikim, I Temel &R OzdemirThe BsmI and FokI polymorphisms in thevitamin D receptor gene in relation toanthropometric and metabolic parametersdescribing metabolic syndromeA Filus, A Trzmiel, J Kuliczkowska-Płaksej,U Tworowska & A MilewiczPOSTERSP315P316P317Endothelial, inflammatory and endocrinemarkers in women with PCOS be<strong>for</strong>e and aftermet<strong>for</strong>min treatmentD Heutling, H Schulz, I Nickel, J Kleinstein,P Kaltwasser, HS Randeva, K Krzyzanowska,F Mittermayer, M Wolzt, G Schernthaner &H LehnertExpression and regulation of adiponectinreceptors (AdR-1 and AdR-2) in pancreaticbeta-cellsJEP Brown, JE Digby, SJ Dunmore & HS RandevaP327P328P329Comparison between NPH insulin and insulinglargine in intensive insulin therapy in type 1diabetes mellitusM Pes˘ic, S Radenkovic, Sživic, M Velojic, D Dimic &D MikicAssociation of C-reactive protein with insulinresistance in first degree relatives of type 2diabetic patientsNE Gulcelik, R Serter, M Ozkaya & Y Aral42www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P330P331P332P333P334P335P336P337P338P339P340P341P342How do glucose, insulin, potassium improvehaemodynamic per<strong>for</strong>mance? Evidence <strong>for</strong>beta-adrenoreceptor and sarcoplasmicreticulum calcium ATPase up-regulationAM Ranasinghe, DW Quinn, CJ McCabe, D Pagano,JA Franklyn & RS BonserEffects of weight loss on the coronary riskprofile in obese patients two years afterbariatric surgeryM Melo, D Rodrigues, MV Campos, J Guimaraes,A Fagulha, J Figueiredo, C Manso, G Tralhão,A Milheiro, F Castro e Sousa & M CarvalheiroThe severity of cardiovascular disease inwomen is modified by estrogen receptor alphapolymorphic variantsM Alevizaki, K Saltiki, I Kanakakis, A Cimponeriu,C Alevizaki, I Georgiou & E AnastasiouAdult pancreatic islet progenitor cells exhibitplasticity in vitroWE Leadbeater, MR Summerfield, DJ Hill, M Berry &A LoganRegulation of hexose-6-phosphatedehydrogenase (H6PDH) in human fetal liverWRL-68 cellsA Swali, I Bujalska, PM Stewart & EA WalkerRelationships between plasma adiponectin andtestosterone concentrations in middle-agedmen and womenJ Zhang, RIG Holt, SH Wild, H Holt, RB Poole,QX Zeng & CD ByrneRelationship between testosterone and in vivoexpression of adipoR1 in skeletal muscle inmiddle aged Caucasian menJ Zhang, H Holt & CD ByrneTestosterone secretion and melatonin rhythmin men with the metabolic syndromeR Robeva, G Kirilov & PH KumanovMortality and morbidity of diabetes patientsIV Misnikova, YA Kovaleva & AV DrevalPrevalence of diabetic foot syndrome amongdiabetes patientsIV Bakharev, IV Misnikova & AV DrevalDecreased cutaneous vasomotor responses inpatients with insulin resistanceP Tretjakovs, A Jurka, K Geldenere, A Stifts, JI Aivars& V PiragsLipid profile in normal weight and obesewomen with polycystic ovary syndromeM Stojkovic, M Zarkovic, J Ciric, B Beleslin, S Savic,M Drezgic & B TrbojevicIs ghrelin a potential signal of decreased fatfreemass in elderly subjects?P Magni, S Bertoli, M Ruscica, E Dozio, V Krogh,M Motta, G Testolin & A BattezzatiP343P344P345P346P347P348P349P350P351P352P353Obesity and expression of serotonintransporter (SERT) in human plateletsA Marsili, F Santini, C Pelosini, L Betti, L Fabbrini,G Galli, I Ricco, S Baroni, P Italiani, P Fierabracci,G Giannaccini & A PincheraAcute and chronic effect of teriparatide onglucose metabolism in women withestablished osteoporosisA Anastasilakis, DG Goulis, G Koukoulis, A Slavakis,M Kita & A AvramidisAdipose glucocorticoid synthesis: transcriptionof the 11β-hydroxylase gene in omental butnot subcutaneous adipose tissueSM MacKenzie, CJ Kenyon, DEW Livingstone,R Andrew, R Fraser, JMC Connell & E DaviesMetabolic syndrome among patients withprimary aldosteronism: a common feature?G Giacchetti, V Ronconi, F Turchi, L Agostinelli,S Rilli & M BoscaroMetabolic parameters in patients with primaryaldosteronism: relation to SNPs of theadiponectin geneV Ronconi, L Agostinelli, F Turchi, S Rilli, M Boscaro& G GiacchettiCoronary artery disease and heart failure indiabetic patients in the north of PortugalC Neves, JL Medina & F LopesPhysiological concentrations of testosteroneinhibit extracellular calcium entry via voltagegatedcalcium channels in the A7r5 vascularsmooth muscle cell line - a non-genomiceffectJ Hall, RD Jones, KS Channer, C Peers & TH JonesComparison between premixed insulin as part30 vs premixed human insulin 30/70 incombination with met<strong>for</strong>min in obese type 2diabetic patientsD Mikic, MV Golubovic, M Pesic, R Kocic,S Radenkovic, D Dimic & S AnticEffect of repaglinide vs glimepirid onglycaemic control in overweight and obesepatients with type 2 diabetes mellitusuncontrolled by met<strong>for</strong>minMV Golubovic, D Mikic, M Pesic, D Dimic,S Radenkovic & R KocicAssociation of an insertion/deletionpolymorphism in the alpha 2B adrenergicreceptor with essential hypertension indiabetic patientsDP Papazoglou, KP Papatheodorou, NP Papanas,LP Papazoglou, PP Papathanasiou, TE Exiara,DC Christakidis & EM MaltezosThe metabolic syndrome and insulin resistancein polycystic ovary syndrome - study of over40 casesC Neamtu, I Gherlan, C Boanta,A Caragheorgheopol & C Dumitrachewww.ece2006.com 43POSTERS
8th European Congress of <strong>Endocrinology</strong>P354P356P357P358P359P360P361P362P363P364Prevalence of registered diabetic nephropathyand its terminal stagesVA Gubkina, IV Misnikova, AV Dreval &ON VetchinnikovaNon-insulinoma pancreatogenoushypoglycaemia syndrome (NIPHS) caused byan activating glucokinase mutationHBT Christesen, K Brusgaard, H Beck-Nielsen,J Malec & B Brock JacobsenRelationship between plasma visfatin levelsand the metabolic variables in metabolicsyndromeA Sonmez, T Dogru, I Tasci, I Yilmaz, M Pinar,I Naharci, N Bingol, S Kilic, A Demirtas, S Bingol,U Musabak, T Ozgurtas, K Erbil & S ErikciThe vasodilatory action of oestrogen inisolated human pulmonary arteriesAM Smith, RK Sandher, RD Jones, TH Jones &KS ChannerThe effect of fluvastatin on adiponectin andinsulin sensitivityA Sonmez, T Dogru, I Tasci, I Yilmaz, M Pinar,I Naharci, N Bingol, S Kilic, A Demirtas, S Bingol,U Musabak, T Ozgurtas, K Erbil & S ErikciLeptin as a regulator of serum acylated ghrelinin normal-weight and obese premenopausalwomenA Kempa, B Krzyżanowska-Świniarska,T Miazgowski & K PilarskaInsulin receptoropathies are distinguishedfrom other syndromes of severe insulinresistance by elevated plasma adiponectinlevelsRK Semple, MA Soos, CM Mitchell, JC Wilson,J Luan, EK Cochran, NJ Wareham, P Gorden, VKKChatterjee & S O'RahillyImpaired endothelial function in young nonobesewomen with polycystic ovary syndrome:normalization after therapy with ethinylestradiol-cyproterone acetateM Kravariti, KK Naka, N Kazakos, LK Michalis,A Tsatsoulis & S KalantaridouCarbohydrate metabolism in children withDown's syndromeE Wojcik, E Barg, M Gromkowska, B Wikiera &E MaslowskaAnti-oxidative effect of 17beta-estradiol inhuman endothelial cells: the role of Bcl-2W Zhong & SL AtkinEmergence of new addictions following gastricreduction surgery <strong>for</strong> morbid obesityJ O'Connell, R Yoder, O Fogarty, J Geoghegan &D O'SheaP367P368P369P370P371P372P373P374P375Increased prevalence of the metabolicsyndrome by NCEP, WHO and IDF criteria inwomen with PCOSAJ Cussons, J Shaw, BGA Stuckey, GF Watts &P ZimmetEstrogen receptor alpha (ER'alpha') genepolymorphisms and first-ever primaryintracerebral hemorrhage (PICH)M Strand, I Söderström, P-G Wiklund, G Hallmans,L Weinehall, S Söderberg & T OlssonThe metabolic control levels of 548 diabeticoutpatients compared with the currentguidelines of Polish Diabetes Association (PDA)J Malicka, M Kurowska, JS Tarach & A NowakowskiIncreased sub-clinical inflammation andmarkers of vascular injury in obese childrenAL Harte, AR Baker, ML Hill, L Gilardini, A Girola,NF da Silva, C Invitti, S Kumar & PG McTernanClinical, functional and polysomnographicsparameters in severely obese patientsM Giannetti, F Santini, M Di Giorgio, G Scartabelli,P Fierabracci, A Marsili, R Valeriano, I Ricco, G Galli,A Pucci, N Carpenè, P Vitti, A Palla & A PincheraThe role of tumour necrosis factor-alpha ininsulin-stimulated endothelial nitric oxideproductionSA Ritchie, JMC Connell & IP SaltCorrelation of WBC and PLT count withparameters of type 2 diabetes mellitusKP Papatheodorou, NP Papanas, DP Papazoglou,GD Dimitriadis, LP Papazoglou, EN Ntakomyti,SK Kotsiou & EM MaltezosField evaluation of a multi-sensor armband inGreek womenDP Papazoglou, LP Papazoglou, TP Papadopoulos,NP Papanas, KP Papatheodorou, SK Kotsiou &EM MaltezosThe acute stimulation of nitric oxide synthesisby rosiglitazone in human aortic endothelialcells is independent of the PPAR gammareceptor but is dependant on the fuel sensingenzyme AMPKJG Boyle, IP Salt, SJ Cleland & JMC ConnellP376 Dehydroepiandrosterone in relation to obesity,insulin resistance and lipid spectra in Czechnon-diabetic populationB Bendlova, J Vcelak, D Vejrazkova, M Vankova,K Dvorakova, J Vrbikova, M Hill, L Starka &K VondraP377 Frequency of dyslipidaemias in children -results of lifestyle interventionVA Petrou, AK Tertipi, E Posnaghidou, ED Kostakioti,VT Skarpa, M Anastasakou & C HadjiathanasiouP378 SiRNA-mediated depletion of synaptotagmin-11 abrogates insulin-stimulated glucoseuptake in 3T3-L1 adipocytesSCM Miller, P Mitra, JMC Connell & GW GouldP365POSTERSP366Is the male androgenetic alopecia the sign ofmale equivalent of polycystic ovary syndromeor metabolic syndrome?M Duskova, L Starka, M Hill, M Dolezal,K Simunkova & I Cermakova44www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P379P380P381P382P383P384P385P386P387P388Chromosome 1p shows significant linkage tosteroid metabolism in hypertension in theBritish Genetics of Hypertension StudyS Padmanabhan, R Fraser, M Ingram, E Davies,PB Munroe, R Dobson, M Brown, N Samani,D Clayton, M Farrall, J Webster, M Lathop,M Caulfield, AF Dominczak & JM ConnellImpaired glucose metabolism in patients withCushing's syndromeGA Arnaldi, TM Mancini, BP Polenta,MC Cardinaletti, PC Canibus, EF Faloia &MB BoscaroEffects of bariatric surgery on preclinicalmyocardial alterations in severe obesity andthe related role of insulin resistanceA Pucci, F Santini, V Di Bello, A Marsili,P Fierabracci, A Di Cori, C Palagi, MG Delle Donne,M Giannetti, M Anselmino, P Vitti, A Balbarini &A PincheraThe effect of an 18 week group exerciseeducation program on weight, physicalactivity, cardiovascular fitness, quality of lifeand attitudes to exercise in obese Irish femaleadultsA Quinn, E Fogarty & D O'SheaDirect effect of cannabinoids and ghrelin onliver and adipose cell metabolism via the AMPactivatedprotein kinase (AMPK) enzymeP Dalino, D Aguilar, AM Isidori, E Hubina,EA Garcia, B Kola, AB Grossman & M KorbonitsExpression and localisation of human tissuekallikrein in transfected human embryonickidney cells (HEK-293). Development of anovel panel of monoclonal antibodies (mAbs)against human tissue kallikreinYC Pham, PA Meadows & JN HarveyDietary regulation of peripheral glucocorticoidaction: comparison of saturated andunsaturated fatsTY Man, L Ramage, A Gokcel, Z Michailidou,CJ Kenyon, K Chapman, JR Seckl & NM MortonThe KCNJ11 E23K and UCP2 G-866A SNPs inrelation to DM2 in Czech populationD Vejrazkova, M Vankova, P Lukasova, J Vcelak,H Kvasnickova, K Vondra & B BendlovaAndrogen regulation of hepatic glucocorticoidmetabolism in obese Zucker ratsDEW Livingstone, P Barat, CR McDonnell, BR Walker& R AndrewPlasma N-terminal pro-brain natriureticpeptide and adiponectin levels increasesduring weight lossC Kistorp, H Bliddal, A Flyvbjerg, J Frystyk,P Hildebrandt & J FaberP389P390P391P392P393P394P395P396P397P398P399P400Multiple signalling pathways are involved inthe phosphorylation of ERK1/2 uponactivation of human OX1R and OX2R:evidence <strong>for</strong> differential modulation by orexin-A and orexin-BJ Tang, J Chen, H Lehnert & HS RandevaAssociation among individual deprivationusing the EPICES score and anthropometricfactors linked to abdominal and metabolicmarkersH Bihan, G Nguyen, R Cohen, C Menu, K Soufi,G Reach & H LeClésiauMapping of adiponectin and adiponectinreceptors in the human adult and fetal heartJ Chen, M Lencioni, E Karteris, H Lehnert &HS RandevaTestosterone replacement therapy reducesinsulin resistance and improves glycaemiccontrol in hypogonadal men with type 2diabetesD Kapoor, E Goodwin, KS Channer & TH JonesFunctional analysis of cardiac orexin receptors:preferential activation by OR-BJ Chen, E Karteris, G Rodrigo, P Stanfield, A Ng &HS RandevaOrexin receptor expression in human adiposetissue: differential effects of orexinsJE Digby, J Chen & HS RandevaInsulin sensitivity and lipid profile in obese andnormal weight hypertensive subjectsS Ognjanovic, M Petakov, DJ Macut, T Isailovic,B Popovic, I Bozic & S DamjanovicHuman adipocytes attenuate cardiomyocytecontraction. A direct link between heart failureand obesityV Lamounier-Zepter, M Ehrhart-Bornstein,P Karczewski, SR Bornstein & I MoranoDietary potassium driven responses in therenal WNK kinase pathway in vivoM O'Reilly, E Marshall, T MacGillvray, M Mittal,CJ Kenyon & RW BrownThe in vitro and in vivo role of diabetic statusand insulin sensitisers on the noveladipocytokine, visfatinKC McGee, NF da Silva, AR Baker, AL Harte,SJ Creely, MJ Hill, M Khanolkar, M Evans, S Kumar& PG McTernanAdrenocortical function in obese Zucker ratsCJ Kenyon, DEW Livingstone, AD McNeilly, E Davies,R Andrew & SM MacKenzieRecurrence rate of atrial fibrillation inamiodarone-induced hyperthyroidismRA Trifanescu, S Fica, D Dimulescu, C Barbu,I Coman, C Ceck, R Bunghez & M Coculescuwww.ece2006.com 45POSTERS
8th European Congress of <strong>Endocrinology</strong>POSTERSP401P402P403P404P405P406P407P408P409P410P411The effect of hyperthyroidia on glycemiccontrol in patients with diabetes mellitusS Fica, C Barbu, A Lazar, M Grigorescu, A Albu &R BunghezFlow mediated dilatation and sVCAMconcentration as the markers of endothelialdysfunction in patients with acromegalyM Bolanowski, M Kaluzny, J Daroszewski & A SzubaLow endogenous testosterone induces fattystreak <strong>for</strong>mation following cholesterol feedingin the testosterone deficient testicularfeminised mouse and castrated maleJE Nettleship, RD Jones, CM Biggins, KS Channer &TH JonesTestosterone replacement reduces aortic fattystreak <strong>for</strong>mation in testosterone deficient Tfmmice following feeding on a cholesterolenricheddietJE Nettleship, RD Jones, CM Biggins, KS Channer &TH JonesGrowth hormone and IGFBP-3 but not IGF-Iare independent predictors <strong>for</strong> insulinsensitivity in healthy subjects: on the role ofhGH in the metabolic syndromeMA Arafat, F Perschel, C Schöfl, M Weickert,J Purschwitz, H Rochlitz, J Spranger, M Möhlig &AFH PfeifferDehydroepiandrosterone inhibitsdifferentiation, proliferation and 11βhydroxysteroiddehydrogenase type 1 activityin human preadipocytesJ McNelis, IJ Bujalska, PM Stewart & W ArltUrocortin 2 mediates glucose utilization andinsulin sensitivity in skeletal muscleA Chen, B Brar, CS Choi, D Rousso, J Vaughan,C Donaldson, S Smith, C Li, SN Kim, T Nagy,G Shulman, KF Lee & W ValeElevated serum hs-CRP in the obese - stillmuch to be explainedM Koziolek, B Krzyzanowska-Swiniarska,M Robaczyk, A Szczerkowska, A Kempa, G Kulig,E Andrysiak-Mamos & K PilarskaLipoprotein Lp(a) in patients with systemiclupus erythematosusP Athanassiou, I Kostoglou-Athanassiou, A Kordalis,TH Kalogirou, CH Galanaki, E Bastakis &PH KaldrymidisEffects of alcoholic extract of walnut (Juglansregia L.) septum on serum lipids and activitesof aminotransferase enzymes in streptozocininduced diabetic ratsR Hadjikhani & J SolatiThe ways in which zinc enters beta cells in thepancreas and the influence of zinc blockers onthe development of type 1 diabetesT Priel, M Hershfinkel & I SeklerP412 Lipoprotein Lp(a) in patients with rheumatoidarthritisP Athanassiou, I Kostoglou-Athanassiou, A Kordalis,TH Kalogirou, CH Galanaki, E Bastakis &PH KaldrymidisP413 Polymorphisms in insulin-like growth factorbinding protein-1 (IGFBP-1) are associatedwith altered circulating IGF-I and lower bodymass index in type-2 diabetes mellitusAH Heald, RH Stephens, P McElduff, K Kaushal,K Siddals, JP New, J Worthington, WE Ollier &JM GibsonP414 Polymorphisms in insulin-like growth factorbinding protein-1 (IGFBP-1) are associatedwith increased type-2 diabetes mellitusprevalenceAH Heald, RH Stephens, P McElduff, K Kaushal,JP New, J Worthington, WE Ollier, N Pendleton,M Horan, A Payton & JM GibsonP415 Cardiac autonomic neuropathy in relation tosome components of metabolic syndrome innewly diagnosed type 2 diabetic patientsMA Nishnianidze, RB Kurashvili, MG Khelashvili,E Shelestova, LR Tsutskiridze & MG BekaiaP416 Severity of depression in patients with type 1and type 2 diabetes and its relation to thelevel of glycemia control and anti-depressivetherapyLR Tsutskiridze, RB Kurashvili, GR Kurashvili,MG Khelashvili, MA Nishnianidze, EL Shelestova &MG DunduaP417 Cardiac autonomic and peripheral neuropathyin newly diagnosed type 2 diabetic patientsGR Kurashvili, RB Kurashvili, MG Khelashvili,LR Tsutskiridze, EL Shelestova & MN KobaidzeP418P419P420P421P422Rapid effect of repaglinide in combinationwith met<strong>for</strong>min in poorly controlled obesepatients with type 2 diabetes mellitusRB Kurashvili, NG Asatiani, MG Nishnianidze &EL ShelestovaImpact of migration on circulatingadipocytokines in an Asian Indian populationAH Heald, J Patel, D Prabharakan, S Anderson,E Hughes, A Vyas, D Bhatnagar, S Reddy,P Durrington & JK CruickshankMigration to the UK results in significantlylower testosterone levels in South Asian menJV Patel, N Panja, D Prabharakan, S Anderson,A Vyas, D Bhatnagar, P Durrington, JM Gibson,E Hughes, S Reddy, JK Cruickshank & AH HealdPrevalence of skin manifestation in diabeticpatients in Ahvaz University Diabetes CenterH Shahbazian, R Yaghoobi & R MeamariCorrelations between leptin, insulin resistanceand lipid profile in postmenopausal womenC Poiana, L Stoian & AM Stefanescu46www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P423P424P425Correlation between glycemia levels andmortality rate in patients with type 2 diabetesand prior myocardial infarctionM Dundua, N Asatiani, R Kurashvili, M Khelashvili,L Tsutskiridze & E ShelestovaLeft ventricular geometry and contractileability in type 2 diabetes and non-diabeticpatients with mild hypertensionN Beridze, I Bochorishvili, M Iashvili, R Kurashvili &M DunduaEffect of lacidipine on left ventricular mass andblood pressure circadian rhythm inhypertensive diabetic patientsT Akhobadze, R Kurashvili, M Khelashvili,L Tsutskiridze, E Shelestova, M Dundua, K Paghava,T Kajaia & T KhidesheliEndocrine disruptorsP426 Prevalence of the phyto-oestrogen urinarymetabolites enterodiol and enterolactone inpatients under endocrine investigationL Reilly, L Scobbie, CA Dorrian & AM WallaceP427 Comparative review of primary and secondaryempty sella syndromeMB Babarina, IA Gracheva & EI MarovaP428 Adult's primary empty sellaM Rezzoug, L Zadoud, L Cherf & F ChentliP429P430P431P432P433The UV filter benzophenone 2 inactivateshuman recombinant thyroperoxidase in vitroand disturbs thyroid hormone homeostasis inratsC Schmutzler, A Bacinski, P Ambrugger, H Klammer,W Wuttke, A Grüters, H Jarry & J KöhrleEndocrine disorders in thalassaemia - localexperience in an inner city hospital inBirmingham, EnglandKK Gangopadhyay, G Das, W Burbridge, C Wright& P DeExtracts of black cohosh (Actaea racemosa)inhibit growth of MCF-7 and MDA-MB-231breast cancer cells and dose-dependentlyinhibit oestrone sulphatase activitySA Whitehead, C Kotalla, S Rice & HD MasonAndrogen-dependent Sertoli cell proliferationas a target <strong>for</strong> endocrine disruptors relevant tohuman male reproductive healthH Scott, N Hallmark, PTK Saunders, G Verhoeven,K De Gendt, G Hutchison & RM SharpeA randomized, open-label, multicenter studyto evaluate octreotide LAR with surgicaltherapy as primary therapy in patients withacromegalyA Colao, H Bouterfa, P Cappabianca, P Caron,E De Menis, A Farrall, M Gadelha, A Reed,M Reincke, M Safari, G T'Sjoen & R CuneoP434P435P436Origin of dysgenetic areas in testes of ratsexposed to di-n-butyl phthalate (DBP) duringfetal life: a model of human testiculardysgenesis syndromeIK Mahood, HM Scott, N Hallmark, C McKinnell,M Walker, JS Fisher & RM SharpeEndocrine disruptors and idiopathicgynecomastia with aromatase genepolymorphismIK Czajka, S Zgliczynski & W ZgliczynskiLoss and resumption of ovarian function aftermitotane administrationI Kostoglou-Athanassiou, M Goula, P Athanassiou &PH KaldrymidisEndocrine tumours and neoplasiaP437P438P439Estrogen receptor alpha and beta (ERα and -β)gene and protein expression in breast cancercell lines: verification by RT-PCR and WesternblottingMD Al-Bader, CHJ Ford, J Jacob, LJ Jacob &SS MohanChallenges associated with the diagnosis,differential diagnosis and treatment of 4 casesof ACTH-dependent Cushing's syndrome dueto intermittent hypercortisolismJR Lindsay & LK NiemanHyperprolactinaemia in a series of adults withcraniopharyngiomas and Rathke's cleft cysts:what are the upper limits?G Thanabalasingham, N Karavitaki, N Meston,HE Turner & JAH WassP440 Parathyroid scintigraphy <strong>for</strong>hyperparathyroidism, an assessment ofper<strong>for</strong>manceT Vizhalil Paul, N Thomas, M Seshadri,S Rajaratinam, K Sudeep & J Jubbin JaganP441 Insulinomas - an experience from a tertiarycare institution in South IndiaT Vizhalil Paul, N Thomas, M Seshadri,K Senthilvasan, E Esther & K SudeepP442 Biological diagnosis of 63pheochromocytomas and/or paragangliomasM d'Herbomez, C Bauters, N Rouaix, G Forzy,C Do Cao, B Carnaille & JL WemeauP443 Dedifferentiated papillary thyroid cancer. Useof array CGH in searching <strong>for</strong> prognosticmarkersA Gazdag, G Pocsay, R Pocsay, L Puskas, L Feher,E Tarko & M TarkoP444 Stereotactic con<strong>for</strong>mal radiotherapy inpituitary adenomas - outcome in 36consecutive patients during years 1996-2004C Schalin-Jäntti, L Valanne, M Kouri & T SaneP445Intra-ovarian adrenocortical carcinomaF Chentli, F Yesli, N Meziani, S Alem, N Kesri &S Fedalawww.ece2006.com 47POSTERS
8th European Congress of <strong>Endocrinology</strong>POSTERSP446P447P448P449P450P451P452P453P454P455P456P457P458P459Comparative efficacy of therapy bysandostatin and parlodel of patients withacromegaliaZY Khaimova & AA KhalikovaPituitary tumors in Republic of CroatiaM Vrkljan, A Maric, M Matovinovic, V Cerina,D Herman & HI PecinaHistological pecularities of pituitary adenomasZY Khalimova & ER MagdievaSurgical treatment in acromegaly: predictorsof outcomePV Iushkov, NN Molitvoslovova, EG Luljeva &EI MarovaPituitary mass and hypothyroidism. A casereportH Smida, R Bouguerra, L Ben Salem, N Younsi,CH Saidi & C Ben SlamaIncidence rate of thyroid cancer in Olsztynregion in the years 1993-2004E Bandurska-Stankiewicz & E Aksamit-BiałoszewskaA typical clinical picture of four insulinomacasesM Kurowska, J Malicka, JS Tarach & A NowakowskiWhat is the best glycaemic index <strong>for</strong> diagnosisof insulinoma?JM Andrieu, DB Bassiri, RM Ramdani, EG Guzman,JF Fabre, EA Aboud & JC CourregesSustained correction of hypercortisolism with alow dose mitotane regimen in a youngwoman with PPNAD and Carney ComplexM Campo, G Picca, ED Laudadio, O Lamacchia &M CignarelliHypocorticism after radiosurgery(protonotherapy) in patients with normal MRIand in patients with confirmed tumor <strong>for</strong>Cushing's diseaseOV Manchenko & EI MarovaPrognostic value of Ki-67 expression in thecytologic identification of pancreaticendocrine tumors: preliminary dataMF Manzoni, GM Franchi, C Piani, C Cappelletti,PG Arcidiacono, L Albarello, C Doglioni & E BosiDifficulties in diagnosing persistentacromegaly using current consensus criteria<strong>for</strong> cure after transsphenoidal surgeryM Petakov, M Djurovic, S Ognjanovic, DJ Macut,T Isailovic, B Popovic, I Bozic, M Joksimovic &S DamjanovicCarbohydrate metabolism in patients withhypercorticismV Chachibaia, M Korinteli, E Giorgadze,B Gvadzabia & K BochorishviliRole of family history <strong>for</strong> diabetes mellitus indetermining insulin resistance in acromegalicpatientsF Diacono, D Pietrobono, G Bassotti, L Borgognoni,D Di Sarra, R Iuorio, P Gargiulo & G TamburranoP460P461P462P463P464P465P466P467P468P469P470P471P472Familial acromegalyG Oruk, O Kucuksahin, D Soysal, E Tatar &C OzdemirRole of complex Cdk4/cyclin D1 insomatostatin subtype 2 receptor-mediatedinhibition of cell proliferation of a medullarythyroid carcinoma cell line in vitroF Tagliati, MC Zatelli, A Bottoni, D Piccin, A Luchin,MD Culler & EC degli UbertiSelective cyclo-oxygenase 2 inhibitors revertchemoresistance in medullary thyroidcarcinoma by a mechanism mediated by P-gpand PGH2MC Zatelli, A Luchin, D Piccin, F Tagliati, A Bottoni,C Vignali, M Bondanelli & EC degli UbertiAn intrasellar germinoma with normalcerebrospinal fluid β-HCG concentrationmisdiagnosed as hypophysitisS Tanyolac, A Cikim, N Ozbey, A Sencer, R Kurt,S Sencer, I Turantan & S MolvalilarResponse to medical treatment in malemacroprolactinomasF Chentli, S Azzoug & S BoudiarNon-functioning pituitary tumorsF Chentli, N Meziani, K Takbou, C Habbak,S Bendaoud, L Cherf & AEM HaddamDiabetic retinopathy in acromegalyS Azzoug, A Adem & F ChentliMalignant catecholamine-secretingparagangliomas of retrocardial localizationM Sabljar-Matovinovic, I Prkacin, N Crkvencic,S Gracin & M KnotekShort-term evaluation of quality of life inacromegalic patientsC Sardella, C Cosci, S Gavioli, F Bogazzi &E MartinoOctreotide as alternative to surgicaladrenalectomyD Katalinic, G Mirosevic & V Zjacic-RotkvicInhibition of IGF-II signal transductionimproves chemosensitivity in humanadrenocortical cancer cellsS Hahner, E Beidinger, A Stuermer, AC Koschker,D Weismann, M Fassnacht & B AllolioThe new TNM classification is inferior to theLee classification in predicting outcome inpatients with adrenocortical carcinomaM Fassnacht, AC Koschker, S Hahner, U Maeder,D Weismann, T Linden, M Quinckler, H Willenberg,P Bucsky, S Diehl, M Brauckhoff, M Schaefer,N Schlenz, K Muessig, M Reincke & B AllolioStimulated and spontaneous growth hormonerelease in irradiated acromegalic patientsAA van der Klaauw, AM Pereira, SW van Thiel,JWA Smit, EPM Corssmit, NR Biermasz, M Frohlich,A Iranmanesh, JD Veldhuis, F Roelfsema &JA Romijn48www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P473P474P475P476P477P478P479P480P481P482P483P484P485P486WNT4 expression in normal human adrenalsand adrenocortical tumoursT Kuulasmaa, J Jääskeläinen, T Pietiläinen,S Loimas, S Aaltomaa, P Heikkilä, V-M Kosma &R VoutilainenThe clinical particularities, medical possibilityof prolactinomas in menLK Dzeranova, VV Vax & EN GiniatullinaManagement of thyroid cancer in childrenA Mazilu, AE Ranetti, A Mihai & C SpiroiuDiagnosis difficulties in insulinomasAE Ranetti, A Mazilu, C Spiroiu & A MihaiInsulin-like growth factor-I signalling intamoxifen sensitive and tamoxifen resistantbreast cancer cellsCJ McVittie, S Khalaf, W Ogunkolade, R Carpenter,SA Bustin & PJ JenkinsFunctioning adrenocortical carcinoma and theclinical endocrinologist: toxic treatments andpoor prognosisRM Thomas, R Bliss, D Richardson, S Johnson,S Turner, S Bennett & R QuintonPost-operative serum cortisol <strong>for</strong> prediction oflong-term remission from Cushing's syndromeJR Lindsay, EH Oldfield & LK NiemanAn in-frame complex germline mutation in thejuxtamembrane intracellular domain causingRET activation in familial medullary thyroidcarcinomaL Fugazzola, D Cordella, M Muzza, L Alberti,P Travaglini, P Colombo, P Beck-Peccoz & L PersaniMacroprolactinoma: 5 casesI Hadj Ali, H Cheikhrouhou, K Khiari &N Ben Abdallah48h appears as sufficient duration of fasting inthe diagnosis of insulinoma - a single centreexperience with 23 casesM Quinkler, F Strehlow, H Biering, M Pirlich, H Gerl,CJ Strasburger & M VentzA case of a patient with differentiated thyroidcarcinoma and metastases to the kidneysZ Adamczewski, J Makarewicz, M Knapska-Kucharska, L Oszukowska, A Karwowska &A LewinskiDevelopment of a non-isotopic immunoassay<strong>for</strong> the measurement of aldosterone in salivaJ Manolopoulou & M BidlingmaierThyroid autoimmunity and breast cancer (BC):absence of morphological autoimmunechanges in breast malignant tissueEG Giustarini, AP Pinchera, PF Fierabracci,DC Campani & CG GianiPituicytoma - a case reportP Rao-Balakrishna, C Dang, K Gnanalingam, H Reid& T KearneyP487 PTTG promotes a novel VEGF-KDR-ID3autocrine mitogenic pathway in thyroidcancerDS Kim, MA Buchanan, AL Strat<strong>for</strong>d, R Susarla,JC Watkinson, MC Eggo, JA Franklyn & CJ McCabeP488 Multiple endocrine neoplasia type 1 (MEN 1)is associated with insulin resistance and anincreased prevalence of diabetes and impairedfasting glucoseRW McCallum, V Parameswaran & JR BurgessP489 Evaluation of a standardized protocol <strong>for</strong> thecollection and storage of adrenal tumorsamples - preparation <strong>for</strong> a European adrenaltumor bank (ENS@T)I Johnsen, S Hahner, M Fassnacht, J Bertherat,X Bertagna, PF Plouin, M Reincke, B Allolio &F BeuschleinP490 Value of overnight dexamethasonesuppression test (1mg-DST) in subclinicalCushing's syndromeZ Penezic, M Zarkovic, M Ivovic, S Vujovic, J Ciric,BZ Beleslin, M Stojanovic, LJ Marina & M DrezgicP491 Effect of catecholamine uptake inhibition oncatecholamine content in human adrenalchromaffin cells and pheochromocytesJ Rosmaninho-Salgado, AR Álvaro, D Grand,A Mota, E Grouzmann & C CavadasP492P493P494P495P496P497PTTG binding factor (PBF) can trans<strong>for</strong>m cellsindependently of interaction with PTTGAL Strat<strong>for</strong>d, K Boelaert, DS Kim, JA Franklyn &CJ McCabeCarney's complex with acromegaly as theleading clinical conditionLM Fatti, G Bertola, G Balza, E Lavezzi, F PecoriGiraldi & F CavagniniDaily profiles of aldosterone secretion inprimary aldosteronismJ Ciric, M Zarkovic, B Beleslin, Z Penezic,M Stojkovic, S Savic & B TrbojevicAnalysis of succinyl dehydrogenase (SDH)subunits gene mutations in patients withparagangliomasA Krawczyk, K Hasse-Lazar, A Pawlaczek,D Rusinek, S Szpak-Ulczok, M Peczkowska,A Preibisz, A Kubaszek, E Gubala, A Januszewicz &B JarzabNeuropeptide Y-Y1 receptors mediate theeffects of neuropeptide Y on prostate cancercell growthM Ruscica, E Dozio, M Motta & P MagniDifferential expression of neurogenins byhuman pituitary adenomasA Fratticci, R Padronetti, F Giangaspero, L Ventura,M Piccirilli, V Esposito, A Gulino, E Alesse &ML Jaffrain-Reawww.ece2006.com 49POSTERS
8th European Congress of <strong>Endocrinology</strong>POSTERSP498P499P500P501P502P503Evidence <strong>for</strong> an attenuated 11betahydroxysteroiddehydrogenase type-1response to an inflammatory stimulus inprimary cultures of epithelial ovarian cancerKS Fegan, MT Rae & SG HillierLong-term somatostatin analog octreotidetreatment in insulinoma patientsD Vezzosi, A Bennet, F Courbon & P CaronDevelopment of dopamine agonist resistanceand progression from microadenoma tomacroadenoma in two women withhyperprolactinaemiaD McCall, SJ Hunter, RS Cooke, B Herron,B Sheridan & AB AtkinsonThe rare RET mutation (insTTCTdelG) atcodon 666 is associated with a low penetranceof medullary thyroid carcinoma andpheochromocytomaM Bex, B Decallonne, G Matthijs & E LegiusUse of TRH in addition to CRH stimulationduring bilateral petrosal sinus sampling inCushing's syndrome - long term experienceP Sathiskumar, J Wright & TA HowlettGlucagonoma syndrome - treatment withintensive insulin and high dose vitamin BcomplexNA Phelan, M Shahid, N Correia, T Kyaw Tun,KC Conlon & J GibneyP504 Headaches cured by surgeryA Banerjee, M Balaratnam, W Dhillo, N Mendoza &K MeeranP505 Chromogranin-a in adrenal incidentalomas -marker <strong>for</strong> tumour secretionM Ivovic, Z Penezic, S Vujovic, Lj Marina,M Stojanovic & M DrezgicP506P507P508P509P510A novel germ-line mutation GLY321ARG in theexon 5 of the RET proto-oncogene detected ina family with familial medullary thyroidcarcinomaE Vaclavikova, S Dvorakova, J Duskova, P Vlcek,A Ryska & B BendlovaContemporary management ofmacroprolactinomasAI Palalau, C Miller, NJ Gittoes & AA ToogoodCushing's paraneoplastic syndrome secondaryto recurrent ovarian carcinomaJ Combes, S Chabroux, D Debieuvre & JP OryMolecular, genetic and clinical characterisationof neurofibromatosis type 1-associatedpheochromocytomaB Bausch & HP NeumannAcroBel: a registry and survey on acromegalyin BelgiumM Bex, R Abs, GT Sjoen, J Mockel, B Velkeniers &D MaiterP511P512P513P514P515P516P517P518P519P520The latest safety and efficacy data of patientstreated with pegvisomantI Schreiber, K Forssmann, M Buchfelder, M Droste,K Mann, B Saller & CJ StrasburgerMutation at codon 804 in a Greek kindreddetected by screening of the six RET exons inpatients with medullary thyroid carcinomaN Mytakidis, E Vassiliou, V Liakos, L Papagrigoriou,F Hadzimarkou, I Kostoglou-Athanasiou,G Koutsodontis, A Ladopoulou, T Bei,D Yannoukakos & P KaldrymidisA rare RET gene mutation is found in twoapparently unrelated Greek kindreds withfamilial medullary thyroid carcinomaN Mytakidis, M Zachariou, T Anagnostopoulos,E Vassiliou, D Thomas, A Tertipi, T Rampias,I Konstantopoulou, P Natsis, D Yannoukakos &P KaldrymidisSurgical cure with preserved pituitary functionis rare in acromegalic patients. Results fromthe POTA study (preoperative octreotidetreatment of acromegaly)SM Carlsen, T Schreiner, S Anderud, Ø Johannesen,J Svartberg & J BollerslevDifferent scintigraphic patterns betweensympathetic and parasympatheticparagangliomasMS Gaglianò, L Simi, T Ercolino, L Becherini,R Sestini, M Mascalchi, M Genuardi, V Briganti,G La Cava, C Olianti & M MannellimRNA expression of somatostatin receptorsubtypes in pheochromocytomas/paragangliomasM Mannelli, S Gelmini, F Malentacchi, L Simi,MS Gaglianò, T Ercolino, L Becherini, A Valeri,C Pratesi & C OrlandoA retrospective review of the effect of pituitaryradiotherapy after trans-sphenoidal surgery <strong>for</strong>non-functioning pituitary adenomasP Chellamuthu, I Robertson, MJ Levy & TA HowlettBiochemical characteristics of 'silent' ACTHsecretingpituitary adenomas: preoperativeserum and urine studiesC Maser-Gluth, G Artlich, A Gutenberg &M BuchfelderRadiotherapy and o,p'-DDD induce aninhibition of growth and interfere in the cellcycle in H295-R adrenocortical cell lineA Stigliano, L Cerquetti, B Bucci, P Carlini,D Amendola, S Misiti, R Miceli, U de Paula,E Brunetti & V ToscanoRole of PKA regulatory subunit 2B protein oncortisol-secreting adrenocortical cellsproliferationA Lania, G Mantovani, S Bondioni, E Peverelli,S Ferrero, L Vicentini, S Bosari, P Beck-Peccoz &A Spada50www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P521P522P523P524P525P526P527P528P529P530P531Outcome of management ofcraniopharyngiomas - a contemporary seriesJD Rippin, RD Mitchell, EJ McGregor, AA Toogood &NJ GittoesAnatomo-clinical features in multihormonalprolactinomasD Voicu, C Badiu, D Hortopan, C Stancu,A Caragheorgheopol & M CoculescuGlucocorticoid receptor gene N363S variant inpatients with clinically inapparent adrenaladenomasG Reimondo, I Micossi, D Giachino, S Bovio,B Allasino, F Daffara, A Angeli, M Terzolo &M De MarchiCharacteristics and follow-up of thyroid cancerin patients with hyperthyroidismM Boudina, K Pazaitou-Panayiotou, A Chrisoulidou,A Drimonitis, A Kaprara, E Georgiou & I VainasInvestigation and surgical management ofpancreatic neuroendocrine tumoursFM Coyle, WM Drake, SL Chew, P Jenkins,RR Hutchins, AB Grossman, JP Monson &S BhattacharyaEstrone and cortisol co-secretingadrenocortical carcinoma in a man presentingwith hypogonadotrophic hypogonadism andpainful gynaecomastiaEL Lim, S Razvi, S Vaikkakara, IM Ibrahim, S Turner,S Johnson, JI Mason, TJW Lennard, R Bliss, S Elloitt,D Richardson, RD Neely & R QuintonOrigin and spread of the SDHD p.Y114Cmutation causing head and neckparaganglioma in Trentino, ItalyF Schiavi, Z Erlic, T Savvoukidis, S Demattè,A Del Piano, ME Cecchini, P Amistà, F Grego,F Trabalzini, M Hoffman, A Schwentek, F Mantero,F Branz, HPH Neumann & G OpocherCharacterization of familial non-syndromicpheochromocytomaG Opocher, F Schiavi, M Iacobone, S Sattarova,Z Erlic, M Martella, C Mian, L Zambonin,P De Lazzari, A Murgia, G Favia & F ManteroEndostatin and VEGF levels in serum ofpatients with pituitary tumorsA Gruszka, J Kunert-Radek, M Pawlikowski,H Stepien & A Radek18F-deoxy-D-glucose positron emissiontomography (FDG-PET) increases thedetection rate of recurrent or residualmedullary thyroid cancerA Faggiano, P Ferolla, LC Pezzullo, M Chiofalo,F Milone, N Mozzillo, G Scarpelli, F Santeusanio,G Angeletti, G Lombardi & A ColaoPapillary thyroid microcarcinoma: a low riskneoplasia?GA Lupoli, S Colarusso, A Panico, F Fonderico,F Nappi, F Marciello, A Martinelli, P Cuofano,F Lo Calzo, L Vicedomini & G LupoliP532P533P534The value of fluorine-18 fluorodeoxyglucosePET during follow-up of patients withmedullary thyroid carcinomaGA Lupoli, S Colarusso, A Panico, F Fonderico,F Nappi, F Marciello, A Gonnella, MR Poggiano,E Nicolai, M Salvatore & G LupoliN363S and Bcl I variants in the glucocorticoidreceptor gene and their associations inCushing's syndrome and Addison's diseaseG Arnaldi, G Appolloni, C Polloni, P Romagni,B Polenta, M Cardinaletti, A Falorni & M BoscaroNovel inactivating mutations in four Italiancases of familial hypocalciuric hypercalcemiaF Cetani, S Borsari, M Lemmi, E Pardi, E Ambrogini,A Pinchera & C MarcocciP535 Genetic analyses of familial isolated primaryhyperparathyroidism: implications <strong>for</strong> clinicalassessment and surgical managementC Marcocci, E Pardi, S Borsari, E Ambrogini,M Lemmi, A Picone, E Vignali, G Viccica, P Berti,P Miccoli & F CetaniP536 Non-pancreatic carcinoid tumours -prognostic value of proliferative index (Ki67%)RM Thomas, G Bernstone, S Johnson, D Manas,RA James & P PerrosP537 Somatostatin receptor subtypes 1-5 inpituitary tumors of various etiologies:investigation by immunohistochemistryN Unger, I Serdiuk, W Saeger, H Wiedemeyer,J Van de Nes, S Schulz, D Stolke, K Mann &S PetersennP538P539P540P541P542High per<strong>for</strong>mance liquid chromatography(HPLC) in the follow-up of mitotane therapy ina patient with adrenal carcinomaD Thomas, I Kostoglou-Athanassiou, S Bournazos,N Mytakidis, V Liakos, E Vassiliou, P Athanassiou &PH KaldrymidisMultiple endocrine neoplasia type 1 andangiomyxomaI Kostoglou-Athanassiou, P Athanassiou, D Thomas,N Mytakidis, E Vassiliou, V Liakos & PH KaldrymidisNovel L301R heterozygous mutation of themenin gene in a Hungarian MEN 1 familyP Gergics, K Balogh, M Toth, A Patocs, L Hunyadi,S Czirjak, J Horanyi, A Gyorkos & K RaczDifferences in the presenting biochemical andimaging data in patients with acromegalycaused by pure GH adenomas, adenomas withGH and PRL cell differentiation andplurihormonal adenomasA Fernandez, N Karavitaki, O Ansorge,V Fazal-Sanderson, HE Turner & JAH WassManagement of thyrotrophin-secretingadenoma with octreotide therapyAEC Fountain, NM Neary, ECI Hatfield & K Meeranwww.ece2006.com 51POSTERS
8th European Congress of <strong>Endocrinology</strong>P543Tumor size and gonadotrophinimmunoreactivity of pituitary adenomasC Badiu, C Stancu, O Filip, D Hortopan,V Ciubotaru & M CoculescuP554Developmental control of tissue deiodinasesby cortisol in fetal sheep during late gestationAJ Forhead, K Curtis, E Kaptein, TJ Visser &AL FowdenPOSTERSP544P545P546P547P548P549P550P551P552Carotid arterial intima-media thickness (IMT),a marker of atherosclerosis, does not differ inpatients with acromegaly compared to healthycontrolsAN Paisley, JAL Lawrance, R Murray, SM Shalet &PJ TrainerAcute biliary tract problems are common ondiscontinuation of somatostatin analogue (SA)therapyAN Paisley, ME Roberts & PJ TrainerCell proliferation and outcome of GHsecretingpituitary adenomasL De Marinis, A Bianchi, L Tilaro, F Doglietto,F Veltri, GV Vellone, F Lugli, A Fusco, V Cimino,A Pontecorvi & L LauriolaEfficacy and safety of high doses of longacting somatostatin analogues <strong>for</strong> treatmentof well-differentiated functioningneuroendocrine tumorsP Ferolla, A Faggiano, R Pivonello, G Lombardi,G Angeletti, A Colao & F SanteusanioSurgical debulking of GH secreting adenomasimproves control of acromegaly by lanreotide- a prospective studyJAH Wass, V Fazal-Sanderson, J Byrne, S Rowel,N Karavitaki, P Trainer & HE TurnerDiagnostic utility of dexamethazonesuppression tests in the work-up of Cushing'sdiseaseEJ Roderick, K Collison, N Karavitaki, HE Turner,S Suliman & JAH WassDescriptive epidemiology of thyroid canceroccurring in the population living in theRhône Alpes region: 1998-2004Z Nejjari, L Remontet, F Borson-Chazot, N Bossard,N Berger, M Decaussin-Petrucci, J Estève &G SassolasIn vitro effects of SOM230 on primary culturedpheochromocytoma cellsD Pasquali, G Conzo, V Rossi, G Bellastella,L Maione, A Bellastella & AA SinisiFourier trans<strong>for</strong>m infrared spectroscopy (FTIR)of parathyroid pathologyK Das, N Stone, C Kendall, C Fowler &J Christie-BrownGrowth and developmentP553 Prevalence of the main GH receptorpolymorphisms in GH deficient children and inthe general populationM Filisetti, P Mella, A Pilotta, L Costa, I Sparapani,S Zanola, B Guaragni, B Felappi, E Prandi & F BuziP555P556P557P558P559P560P561P562P563P564P565P566P567Significance of neonatal steroid imprinting andof peripubertal growth hormone excess <strong>for</strong>the development of prostatic hyperplasia inthe ratF Goetz, A Mitroshkin, AV Patchev & W RohdeAdrenal (interrenal) development in thezebrafishTT To, S Hahner, K Rohr, G Nica,M Hammerschmidt, C Winkler & B AllolioComparison of dietary pattern and food habitin urban and rural adolescent girls, Gillan, IranH Pouraram & M AbtahiEffective factors on status of nutritionaleducation in primary school children, Tehran,Iran: a focus group discussion (FGD)M Abtahi, M Abdollahi, M Amini, H Kianfar,M Dadkhah & H PouraramMorphological changes of pituitary region inprimary GH deficiencyJ Bruna & J BrunovaGrowth without growth hormone: normalfinal height of four patients with multiplepituitary hormone deficiencyM Doknic, D Miljic, S Pekic, M Djurovic, V Zivkovic,M Stojanovic, C Dieguez, FF Casanueva &V PopovicRAD21-dependent effects of securin/PTTG andseparase on fetal neuronal NT2 cellsHN Pemberton, K Boelaert, DS Kim, SY Chan,MD Kilby, JA Franklyn & CJ McCabeLeukemia inhibitory factor promotes thechemomigration of immature GNRH neuronsE Dozio, M Ruscica, M Motta, R Maggi & P MagniThe study of nutrition with different saltconcentrations in prenatal period on BP andtissue changes Na and aldosterone level innext generationF HeydarpourSodium, birth weight, adult weight and BP inadulthoodF Alaee & F HeydarpourEmbryonic gene expression affected bydifferent sodium concentrationsM Heydarpour & F HeydarpourSodium changes autonomic nervous responseM Heydarpour & F HeydarpourLipid peroxidation, activity of caspase 3 andapoptosis activation in low birth weightchildrenE Barg, K Gasiorowski, B Wikiera, A Skoczynska,B Turczyn & E Glab52www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P568P569P570P571P572P573P574Growth hormone induced improvement inquality of life does not correlate withreduction in vascular risk in adulthypopituitary patientsRW McCallum, JR Petrie, AF Dominiczak &JMC ConnellThe response of infant's adrenal gland and saltappetite, aldosterone and Na serum level tomother's salt consumptionP Heydarpour & F HeydarpourMaternal testosterone levels during pregnancyare associated with offspring size at birthSM Carlsen, G Jacobsen & P RomundstadMortality in growth hormone deficiencyK Stochholm, C Gravholt, T Laursen, J SandahlChristiansen & A GreenThe cardiovascular risk profile and carotid IMTof adults with partial GH deficiencyRD Murray, G Wieringa, JA Lawrance & SM ShaletDouble blind placebo controlled study on theimpact of rGH replacement on quality of life inpatients with severe growth hormonedeficiencyS González, S Sugunendran & SL AtkinProlonged expression of the ACTH receptor,MC2-R, during 3T3-L1 adipocytedifferentiation is dependent upon switchingpromoter usage to an adipocyte-specific,C/EBP-driven, downstream promoterLA Noon, AJL Clark, PJ O'Shaughnessy & PJ KingNeuroendocrinology and behaviourP575 Association between the LRP5 gene and serumpost-menopausal follicle stimulating hormonelevelsI Zofkova, K Zajickova & M HillP576 Structural analysis of somatotrophs andlactotrophs in annexin 1 null miceT Afzal, JF Morris, JC Buckingham & HC ChristianP577 Dietary supplements <strong>for</strong> stress and obesity comorbiditiesreductionD Dimitrov & L KoevaP578 The impact of hypothalamic-pituitary (h-p)irradiation on the TSH bio/immuno (B/I) ratioin the fed and fasting statesKH Darzy, L Persani, S Borgato, P Beck-Peccoz &SM ShaletP579 Comparison of the catecholaminergicresponse to 2 different stressors in healthymenBC Binnert, SG Seematter, SR Stettler,BS B Beck-Schimmer, SD Spahn & TL TappyP580Effect of gastric bypass and gastric banding onneurotensin levels in morbidly obese patientsM Christ-Crain, R Stoeckli, A Ernst, N Morgenthaler,S Bilz, M Korbonits, A Bergmann, B Mueller &U KellerP581P582P583P584P585P586P587P588P589P590P591P592P593Mental and neuropsychological disorders ofchildren with congenital hypothyroidismYM Urmanova & SM SafarovaHypopituitary patients have a high occurrenceof metabolic syndrome markers and increasedprevalence of cardiovascular risk factorsB Matuszek, E Obel, M Kowalczyk & A NowakowskiSpontaneous GH secretion in the fed andfasting states in cranially irradiated adultcancer survivors with normal peak GHresponses to two provocative tests: does GHneurosecretory dysfunction exist?KH Darzy, RD Murray, HK Gleeson, SS Pezzoli,MO Thorner & SM ShaletThe long-term predictive accuracy of the shortsynacthen (corticotropin) stimulation test <strong>for</strong>assessment of the hypothalamic-pituitaryadrenalaxisA Agha, J Tomlinson, PM Clark, G Holder &PM StewartGH secretion in amyotrophic lateral sclerosisLL Morselli, P Bongioanni, M Genovesi, R Licitra,B Rossi & E MartinoClinical significance of macroprolactinP Álvarez-Vázquez, D Rodríguez Pérez, E ÁlvarezGarcía, C Páramo Fernandez, E Hervás Abad &MA Andrade OliviéADH and thirst function in defence withhypernatremia <strong>for</strong>mationF HeydarpourThe effect of garlic odor on appetite centerF HeydarpourTaste protective mechanism in relation withsaltF HeydarpourThe effect of salt on night sleepF HeydarpourEvaluation of cognitive functions by usingP300 auditory event related potentials (ERPs)in patients with growth hormone (GH)deficiency and GH excessF Tanriverdi, C Suer, H Yapislar, K Unluhizarci,F Bayram & F KelestimurAppetite regulating hormones inconstitutionally lean and anorexia nervosasubjectsB Galusca, N Germain, CW le Roux, D Frere,MA Ghatei, SR Bloom & B EstourDifferentiation of TSH-OMA from thyroidhormone resistance syndrome using thyroidcolor Doppler sonographyC Cosci, C Sardella, L Manetti, M Gasperi,L Tomisti, S Gavioli, E Macchia, F Bogazzi &E Martinowww.ece2006.com 53POSTERS
8th European Congress of <strong>Endocrinology</strong>P594Maternal consumption of a high-meat, lowcarbohydrate diet in late pregnancy and stressresponsiveness in the offspringRM Reynolds, H Simonsen, S Pearson, ME Barker,DJP Barker, M Campbell-Brown, KM Godfrey &DIW PhillipsPatients with pituitary disease who have hadradiotherapy have reduced cerebral vasomotorreactivityN Rathbone, JS Davies & MF ScanlonAn open label, controlled study to assess theability of patients with acromegaly, or theirpartners, to administer somatuline autogelJS Bevan, J Newell-Price & JAH WassP606Effectiveness of the association ofbromocriptine and cabergoline in thetreatment of 05 invasive and giants prolactinmacroadenomaAEM Haddam, S Fedala, S Bouzidi, S Ouahid,NS Fedala, MS Bourouba & D MeskineHypothalamic-pituitary dysfunction followingirradiation of non-pituitary brain tumours inadultsA Agha, M Sherlock, S Brennan, SA O'Connor,E O'Sullivan, B Rogers, C Faul, D Rawluk, W Tormey& CJ ThompsonBone mass and metabolism in activeacromegaly - no impact of gonadal status. astudy of 73 patientsSL Fougner, K Godang, T Ueland, T Schreiner &J BollerslevEffect of pegvisomant on glucose metabolismS Aznar, E Boix, P Revert, O Moreno, A López-Maciá& A PicóPsychological and gastrointestinal problems inanorexia nervosa patientsM Djurovic, D Popovic, S Pekic, I Jovanovic,B Lapcevic, M Petakov, V Zivkovic, M Stojanovic,M Doknic, FF Casanueva, C Diguez & V PopovicOctreotide shrinks the cellular rather than thevascular compartment in acromegalic tumoursin vivoAM Manuchehri, M Lowry, C Rowland Hill,LW Turnbull & SL AtkinPositive correlation between acroqol and SF-36 and negative with BDI in sample of 60acromegalicsM Abreu, D Carvalho, E Vinha, S Webb &JL MedinaQuality of life (QoL) and psychiatric sequelaefollowing aneurysmal subarachnoidhemorrhage (SAH): does neuroendocrinedysfunction play a role?I Kreitschmann-Andermahr, E Poll, B Saller,A Reineke, JM Gilsbach & BO HütterP595P596P597P598P599The effect of dopamine on neuroendocrinedisorders in women with PCOS under chronicstress conditionsDK Virsaladze, K Natmeladze, I Topuria,A Natmeladze & N PaichadzeMeasurement of basal cortisol in serum andsaliva <strong>for</strong> the diagnosis of secondary adrenalinsufficiencyT Deutschbein, N Unger, K Mann & S PetersennSensitivity and specificity of differentprovocative tests <strong>for</strong> the diagnosis ofsecondary hypoadrenalism in patients withhypothalamo-pituitary disordersA Picu, R Giordano, L Bonelli, M Balbo,M Pellegrino, R Berardelli, G Corneli, V Gasco,E Ghigo & E ArvatPulmonary function in Cushing's diseaseT Bayraktaroglu, F Kutluturk, E Turan, Y Orhan &S TanyolacP607P608P609P610P611P600P601P602P603Adenosine stimulates connexin 43 expressionand increases intercellular communication inthe folliculostellate cells of the anteriorpituitary glandBM Lewis, K Francis, A Pexa, A Deussen,MF Scanlon, DA Rees & J HamComplement C5a inhibits the secretion ofmacrophage migration inhibitory factor (MIF)in anterior pituitary cell linesBM Lewis, K Francis, P Monk, MF Scanlon & J HamUnrecognized chronic hypopituitarism inpatients who survived hemorrhagic fever withrenal syndromeM Stojanovic, S Pekic, G Cvijovic, A Kendereski,M Doknic, D Miljic, V Zivkovic, M Djurovic, D Micic& V PopovicGhrelin test <strong>for</strong> the assessment of growthhormone (GH) status in successfully treatedpatients with acromegalyS Pekic Djurdjevic, M Doknic, D Miljic,M Joksimovic, J Glodic, M Djurovic, C Dieguez,FF Casanueva & V PopovicP612P613P614P615Pituitary function in patients with detectableserum pituitary autoantibodiesLL Morselli, L Manetti, I Lupi, S Albertini, L Grasso,R Fessehatsion, M Genovesi, M Gasperi & E MartinoPrevalence of pituitary autoantibodies inthyroid disordersL Manetti, LL Morselli, I Lupi, S Albertini, L Grasso,M Genovesi, R Fessehatsion, S Mariotti & E MartinoRate of change in size of macroprolactinomaswith dopamine agonist therapy - is there anyrelationship to fall in prolactin concentrations?CL Miller, A Palalau, AA Toogood & NJL GittoesPOSTERSP604P605The thickening of the pituitary stem inconnection with 06 casesNS Fedala, AEM Haddam & F ChentliP616P617The levels of ghrelin and leptin and body fatmass in patients treated <strong>for</strong> thyroiddysfunctionJ Brunova, L Karasova & P Kasalicky54www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P618P619P620P621P622P623P624P625P626P627P628P629Night sleep affected by saltR Samadie & F HeydarpourADH and thirst function in defence withhypernatremia <strong>for</strong>mationR Samadie & F HeydarpourTaste protective mechanism in relation to saltF Alaee & F HeydarpourCushing's syndrome as a model to investigatethe effects on cognition of high circulatinglevels of glucocorticoidN Correia, S Mullally, M Shahid, NA Phelan,S O'Mara, T Kyaw Tun & J GibneyThe influence of growth hormonereplacement (GHR) in adults with GHdeficiency (GHD) on body composition, basalmetabolic rate, physical activity and ingestivebehaviourD Deepak, C Daousi, JP Wilding, J Pinkney &IA MacFarlaneInfluence of affective changes on cortisolresponse to ACTHM Zarkovic, J Ciric, B Beleslin, Z Penezic,M Stojkovic, S Savic & B TrbojevicInterest of a single treatment by somatostatinanalogues in a macroadenoma secreting TSHand GHS Lopez, C Combes, A Drutel, F ArchambeaudMouveroux & MP TeissierDehydroepiandrosterone (DHEA) improvespsychological well-being in male and femalehypopituitary patients in addition to growthhormone replacement (GHR)AM Brooke, LA Kalingag, F Miraki-Moud,C Camacho-Hubner, KT Maher, DM Walker,JP Hinson & JP MonsonThe influence of a GH receptor antagonist(GHRA) on the relationship between GH andIGF-I in adults with severe growth hormonedeficiency (AGHD)A Pokrajac, CA Berg, M Bidlingmaier,CJ Strasburger, SM Shalet & PJ TrainerCan adults with severe growth hormonedeficiency (AsGHD) and a low IGF-I bedistinguished from those with a normal IGF-I?CA Berg, A Pokrajac, M Bidlingmaier,CJ Strasburger, K Mann, SM Shalet & PJ TrainerSleep disorders in acromegaly: preliminarydata demonstrating a high prevalence ofrestless leg syndrome (RLS)S Cannavo, R Condurso, S Squadrito, G Romanello,I Arico, G Mento, F Trimarchi & R SilvestriRisk factors <strong>for</strong> the development ofatherosclerosis in patients with acromegalyM Medic-Stojanoska, B Kovacev-Zavisic, LJ Popovic,J Radosavljevic, T Radovanov, I Bajkin, G Mitic &M MitrovicP630P631P632P633P634P635P636P637P638P639P640Microalbuminuria as well as insulin sensitivityare improved under octreotide-LAR treatmentin acromegalic patientsR Baldelli, V Gasco, R Pivonello, A Bianchi,V Cimino, F Galenca, A Pontecorvi, G Lombardi,E Ghigo, A Colao, L De Marinis & S GrottoliPro-opiomelanocortin and ACTH, precursors ofalphaMSH, are secreted from humanmelanocytes and keratinocytes and canstimulate melanogenesisK Rousseau, S Kauser, LE Prtichard, A Warhurst,RL Oliver, CA Schmitz, AJ Thody, DJ Tobin &A WhiteProcessing and sorting of proopiomelanocortinis an important checkpointin regulating release of ACTH from secretoryvesicles in pituitary cellsA Warhurst, RL Oliver, RA Davies, LE Pritchard &A WhiteHormone therapy effects on sleep and dreamsin menopausal womenC Rasanu, D Niculescu, I Botusan, O Filip &M CoculescuGlucose-suppressed GH levels compared withIGF-I levels in patients with acromegalyB Steffin, B Gutt, J Roemmler, M Bidlingmaier &J SchopohlLoss of rise in awakening cortisol response inprepubertal survivors of leukaemia post bonemarrow transplantation and chemotherapytreatmentML Yeap, D Jessop, R Elson, J Cornish, S Lightman& EC CrowneThe incidence of spontaneous cerebro-spinalfluid rhinorrhea in a large series of patientswith macroprolactinomaSGI Suliman, J Byrne, O Ansorge & JAH WassGonadotropin levels in the cerebrospinal fluid(CSF) as a marker of the gonadotropinsecretion from non-functioning pituitaryadenomasML Gheorghiu, C Badiu, A Caragheorgheopol,D Hortopan, A Dumitrascu, S Galoiu, C Capatana& M CoculescuProlonged post-operative follow-up isnecessary <strong>for</strong> unirradiated non-functioningpituitary adenomataKV Allen & JAH WassAnterior pituitary hormone dysfunction aftertraumatic brain injury: less common thanpreviously thought?N Karavitaki, JD Henderson-Slater, DT Wade &JAH WassEffects of long-term GH treatment in Prader-Willi adultsC Hoybyewww.ece2006.com 55POSTERS
8th European Congress of <strong>Endocrinology</strong>P641P642P643P644Endocrine abnormalities are common intranssexual individualsSJ Iqbal, H Baig, R Green, J Barrett & LJ SealGlucagon-induced suppression of ghrelinsecretion is exerted at hypothalamus-pituitarylevel and is not mediated by an increase incatecholamine secretionMA Arafat, F Perschel, B Otto, M Weickert,H Rochlitz, C Schöfl, J Spranger, M Möhlig &AFH PfeifferComplications of hormonal therapy in male tofemale transsexuals is uncommonH Baig, SJ Iqbal, R Green, J Barrett & LJ SealEffects of targeted ablation of GHRH neuronsin mice on anterior pituitary somatotrophsand lactotrophsA Miller, P Le Tissier, I Robinson & HC ChristianP653P654P655P656Psycho-biological correlates of free-floatinganxiety symptoms in male patients with sexualdysfunctionsG Corona, E Mannucci, L Petrone, V Ricca,G Balercia, R Giommi, G Forti & M MaggiHistone deacetylase inhibitors exert estradiolinducedproliferation and hyperplasia<strong>for</strong>mation in the mouse uterusAG Gunin & AA OsipovaAetiologies of galactorrheasF Chentli & D MeskineStandardisation and validation of a sensitiveenzyme immunoassay procedure to estimate13,14-dihydro-15-keto-PGF2α (PGFM) inmithun (Bos frontalis) plasmaDP Mishra, A Dhali, A Mech, M Karunakaran,H Choudhury & C RajkhowaPOSTERSReproductionP645P646P647P648P649P650P651P652Spermatogenesis in autologous testiculartransplants in the non-human primateCallithrix jacchusCM Luetjens, S Schlatt, E Nieschlag, M Simoni &J WistubaHormonal status of women with benignendometrial hyperplastic lesionsAA Osipova, VA Matveeva, AV Samoilova &AG GuninDependence of semen characteristics onabstinence time, testicular volume andhormonesF Tüttelmann, CM Luetjens, TG Cooper, M Simoni& E NieschlagPlasma endothelin-1 levels in patients withmale hypogonadismA Tomova, PH Kumanov & G KirilovOutcome of 59 pregnancies in 43 acromegalicwomenPH Caron, J Bertherat, A Brac de la Périère, TH Brue,C Cortet-Rudelli, F Schillo & PH ChansonDifficulties in achieving versus maintainingerection: organic, psychogenic and relationaldeterminantsG Corona, L Petrone, E Mannucci, M Mansani,G Balercia, C Krausz, R Giommi, G Forti & M MaggiPsycho-biological correlates of smoking inpatients with erectile dysfunctionG Corona, L Petrone, E Mannucci, V Ricca,R Mansani, A Cilotti, G Balercia, R Giommi,V Chiarini, G Forti & M MaggiPsycho-biological correlates of delayedejaculation in male patients with sexualdysfunctionsG Corona, L Petrone, E Mannucci, AD Fisher,G Balercia, R Giommi, V Chiarini, G Forti &M MaggiP657P658P659P660P661P662P663P666Sio<strong>for</strong> efficacy in treatment of obesity andreproductive disordersZY Khalimova & GD NarimovaEndothelin-1 levels in men of reproductive agewith idiopathic hypogonadism after treatmentwith tamoxifen or raloxifeneM Tzoitou, E Papadopoulou, A Papageorgiou,M Kita, V Zournatzi, A Kourtis, A Avramidis &D PanidisClinical, hormonal, neuroradiologicalcharacteristics and response to treatment in29 macroprolactinomasR Bouguerra, L Ben Salem, Z Turki, H Smida,I Kammoun, C Saidi & C Ben SlamaPrevalence of macroprolactinemia duringpregnancy of women with prolactinproducingpituitary microadenomasI Varga, C Jakab, E Toldy, P Gergics, M Toth, R Kiss,N Szucs, P Pusztai, A Patocs, I Adler, E Glaz &K RaczHormone replacement therapy inpostmenopausis fails to normalizegonadotropins - does it matter?J Zmire, P Cvitkovic, P Jukic, B Colak, D Lucinger,L Sokolic, B Rocic & K KljajicAll that is hypogonadal in haemochromatosisis not due to iron depositionEP O'Sullivan & CH WalshNitric-oxide-cGMP and ATP-cAMP pathways inpregnant women with gestation diabetesmellitusZV Zabarovskaya, OD Bichan & AP ShepelkevichThe influenace of estradiol on erythrocyteantioxidative enzyme system activity in preandpostmenopausal womenG Bednarek-Tupikowska, U Tworowska &B Bidzinska-Speichert56www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P667P668P669P670P671P672P673P674P675P676P677P678P679P680The influence of the cimicifuga racemosa onthe vegetovascular and psychoemotionaldisorders in women with climacteric syndromeE Giorgadze, M Korinteli, K Asatiani & M TsagareliGonadal dysfunction in hypercortisolic menF Chentli, H Boudina, K Gati, S Azzoug & NMezianiRole of estrogen receptor α- or β-iso<strong>for</strong>ms insex-specific brain organizationF Goetz, AV Patchev & W RohdeAn immortalised cell line (SK11) derived fromimmature mouse testes express functionallyactive androgen and oestrogen receptorsRP Hooley, SF Sneddon, F Collins & PTK SaundersClinical and laboratory relationships in womenwith hirsutism as a primary symptomI Duncea, CE Georgescu, C Ghervan, A Valea &L GozariuBone mass density in 180 women withpremature ovarian failureS Vujovic, M Stojanovic, Z Penezic, M Ivovic,M Kovacevic, B Barac, L Marina & M DrezgicOxidized low-density lipoproteinautoantibodies in patients with polycysticovary syndromeA Azezli, A Telci, T Bayraktaroglu, F Kutluturk,A Uzum, A Cikim, S Tanyolac & Y OrhanTrans<strong>for</strong>ming growth factor beta 1 anddecidualisation of the human endometriumNM Kane, J Brosens, HOD Critchley & RW KellyEvidence <strong>for</strong> synergy of SHBG and androgenreceptor genes in PCOS phenotypeN Xita, I Georgiou, V Psofaki, G Kolios &A TsatsoulisFactor analysis identifies three independentfactors within PCOSAJ Cussons, V Burke, BGA Stuckey & GF WattsImpaired vascular function in hypogonadalmales is unaltered during treatment cycle withintramuscular testosterone estersHA Lane, JC Smith, K Morris, J Cockcroft,J Goodfellow, MF Scanlon & JS DaviesChanges in GnRH gene expression in themedial basal hypothalamus of rhesusmacaques across the menstrual cycleHF Urbanski, N Noriega, VT Garyfallou, JL Downs &SG KohamaMechanisms of Wolffian duct differentiation;development of a model <strong>for</strong> studyingandrogen-driven stromal-epithelial interactionsM Welsh, RM Sharpe & PTK SaundersNeonatal, but not maternal, plasma lipidprofiles are altered in pregnancy in womenwith polycystic ovarian syndrome (PCOS),compared with weight matched controlsEK Tan, M Kanagalingam, R Fleming, JMR Gill &DJ FreemanP681P682P683P684P685P686P687P688P689P690Kisspeptin-54 stimulates the hypothalamicpituitary-gonadalaxis in human malesWS Dhillo, OB Chaudhri, M Patterson,EL Thompson, KG Murphy, MK Badman,BM McGowan, V Amber, S Patel, MA Ghatei &SR BloomEffect of chronic tadalafil administration onpenile hypoxia induced by cavernousneurotomy in the ratL Vignozzi, A Morelli, S Filippi, S Donati, M Luconi,XH Zhang, S Ambrosini, GB Vannelli, V Mirone,G Forti & M MaggiNeuromedin U (NMU) and neuromedin S(NMS) function as putative regulators of thegonadotropic axis in the ratE Vigo, J Roa, JM Castellano, R Fernandez-Fernandez, VM Navarro, R Pineda, E Aguilar,L Pinilla & M Tena-SempereCircadian changes in melatonin secretion andits relationship to gonadotropins inpremenopausal womenO Ianas, D Manda, R Calarasu, C Busu &D CampeanSerum levels of PSA do not change in healthypre-menopausal and in menopausal women,but are increased in subjects with polycysticovary syndrome (PCOS)A Burelli, E Rineladi, R Cionini, E Benelli, A Pinchera& E PucciExpressions of KISS1 and GPR54 aredifferentially regulated by estradiol and GnRHin adult female rat pituitaryN Richard, G Galmiche, S Corvaisier & ML KottlerAnti-Mullerian hormone (AMH) production byand AMH type II receptor (AMHRII) in normalhuman ovariesL Hanna, L Pellatt, S Rice, S Whitehead & H MasonIdentification and functional study of a newFSH receptor gene mutation in womenaffected by polycystic ovary syndrome (PCOS)E Ferrarini, FJ Orio, S Palomba, T Cascella, ADimida, S di Biase, D Labella, P Agretti, G deMarco, E Gianetti, P Vitti, A Colao, G Lombardi, EPucci, A Pinchera & M TonaccheraPlasma kisspeptin is a novel tumour marker inpatients with gestational trophoblasticneoplasiaWS Dhillo, P Savage, KG Murphy, OB Chaudhri,M Patterson, VM Foggo, GS Dancey, H Mitchell,MJ Seckl, MA Gahtei & SR BloomChronic subcutaneous administration ofkisspeptin-54 causes testicular degeneration inadult male ratsEL Thompson, KG Murphy, M Patterson, GA Bewick,PH Jethwa, GWH Stamp, JF Todd, MA Ghatei &SR Bloomwww.ece2006.com 57POSTERS
8th European Congress of <strong>Endocrinology</strong>POSTERSP691P692P693P694P695P696P697P698P699P700P701P702P703Oxidative stress, endothelial function, andarterial stiffness in young patients withpolycystic ovary syndromeE Benelli, L Ghiadoni, D Giannini, E Rinaldi,Y Plantinga, C Taurino, A Burelli, GP Bernini,A Pinchera & E PucciAldosterone and renin plasma levels in youngpatients with polycystic ovary syndromeGP Bernini, S Bela, R Cionini, M Bardini, A Moretti,E Benelli, E Rinaldi, A Burelli, P Vitti & E PucciAssociation between polymorphisms withinthe SUR1/Kir6.2 gene region and polycysticovary syndrome: a case-control studyTM Barber, E Zeggini, MJ Goh, L Webber, JAH Wass,S Franks & MI McCarthyEffect of family history of type 2 diabetes onmetabolic status of women with polycysticovary syndromeA Vryonidou, I-A Vatalas, V Loi, T Terzi,A Dionyssiou-Asteriou & C PhenekosA review of cimetidine (tagamet) effects as areproductive toxicant in male rat prostate andseminal vesicleE EilatiA review of male rat genital systemmorphology following cimetidine (tagamet)injectionE EilatiA review of cimetidine (tagamet) as areproductive toxicant in male rat Leydig cellsE EilatiFunctional restoration of intact rabbit ovaryafter cryopreservation and transplantationC Chen, S Chen & G WuEffects of met<strong>for</strong>min therapy in lean subjectswith PCOS on insulin resistance indicesY Altuntas, O Basat, S Ucak, S Seber, N Eren,CY Ersoy & K ArslanComparison of various insulin sensivity indicesin idiopathic hirsutismS Ucak, O Basat, S Seber, E Satir & CY ErsoyMet<strong>for</strong>min therapy decreaseshyperandrogenism and hyperinsulinaemia inwomen with polycystic ovary syndromeTME Abdalla, D Wilton, A Wilton, A Wayte,K Griffiths & J HuberA unique subgroup of patients with polycysticovary syndrome identified by clinical andbiochemical featuresTME Abdalla, A Wilton, D Wilton, K Griffiths,A Wayte & J HuberObstetric hazards of maternal obesityS Paiva, L Ruas, M Campos, M Melo, J Guimarães,A Lobo, E Sobral, E Marta, A Cravo & M CarvalheiroP704P705P706P707P708P709P710P711P712P713P714P715Cardiopulmonary impairment in youngwomen with polycystic ovary syndromeF Orio, F Giallauria, S Palomba, T Cascella,A De Lorenzo, R Lucci, F Manguso, L Vuolo,T Russo, G Lombardi, A Colao & C VigoritoMet<strong>for</strong>min decreases CRP level andcardiovascular risk in PCOS womenZ Velija-AsimiFunctional characterization of the folliclestimulatinghormone receptor core promoter:applying a comparative approach amongprimatesM Brune, E Kostova, E Nieschlag & J GromollTestosterone restores diabetes-induced erectiledysfunction and sildenafil responsiveness intwo distinct animal models of chemicaldiabetesS Filippi, A Morelli, L Vignozzi, XH Zhang, M Luconi,S Donati, G Forti & M MaggiAndrogenic status is influenced by ARpolymorphism (CAG repeats number)D Canale, C Caglieresi, C Moschini, E Macchia &E MartinoRole of D327N sex-hormone binding globulingene polymorphism in the pathogenesis ofpolycystic ovary syndromeJ Vrbikova, J Zavadilova, M Vankova, D Vejrazkova,P Lukasova, J Vcelak, K Dvorakova, K Vondra &B BendlovaEndocrine evaluation of a large cohort of malecancer survivors compared with healthycontrolsDM Greenfield, RE Coleman, BW Hancock,HA Davies, J Snowden & RJ RossThe use of prolonged human chorionicgonadotrophin stimulation testing in theevaluation of cryptorchidismJR Dixon, S Murthy, E McNeil, M Wallace, S O'Toole& SF AhmedStage-specific mRNA expression of androgenreceptor correlated with FSH receptor inindividual pre-antral follicles isolated fromhuman ovaryS Rice, K Ojha, S Whitehead & H MasonHyperprolactinaemia due to big prolactinJA Ahlquist, AR Ellis & MN Fahie-WilsonEfficacy of testogel in the treatment ofhypogonadism in routine clinical practiceTH Jones, LR Chilukuri & A MunirWhich clinical features of polycystic ovarysyndrome are improved with met<strong>for</strong>mintherapy? A retrospective studyMA Elrishi, MJ Levy & TA Howlett58www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P716P717P718P719P720P721P722P723P724P725P726SteroidsP727Comparison of insulin resistance levels in preandpost-menopausal women, women withpolycystic ovarian syndrome andpostmenopausal women with type 2 diabetesLW Cho, V Jayagopal, ES Kilpatrick, P Jennings &SL Atkin11β-Hydroxysteroid dehydrogenase (11βHSD)activities in porcine granulosa cells fromovarian follicles and cystsN Sunak, V Sharp, LR Abeydeera, LM Thurston &AE MichaelSecretion of adiponectin by human placenta:differential modulation by cytokinesM Vatish, J Chen, E Karteris, S Zervou, JE Digby,EW Hillhouse & HS RandevaFunctionality of largest follicles is affected ingonadotrophin-stimulated cyclesA Veiga-Lopez, MJ Cocero, V Dominguez,CJH Souza, RM Garcia-Garcia, C Ariznavarreta,JAF Tresguerres, AS McNeilly & A Gonzalez-BulnesScreening <strong>for</strong> gene SRY by FISH in patientswith Turner syndromeJ Guimarães, T Almeida Santos, A Barbosa,M Bastos, A Almeida Santos & M CarvalheiroSerum anti-Mullerian hormone (AMH)concentrations in infants and childrenG Wilson, R Fleming, P Galloway, AM Wallace &SF AhmedPrenatal diagnosis of P450 oxidoreductasedeficiencyHE Ivison, BA Hughes, EM Blair, A Haskins Olney,CHL Shackleton & W ArltIsolated progesterone secretion by an ovarianLeydig cell tumour: I, hormonal andimmunohistochemical characterization; II,effects on the gonadotrope axisH Bry, G Meduri, F Abirached, E Constancis,S Brailly, P Chanson & J YoungSerum inhibin levels in patients with polycysticovary syndromeM Lankarani & N ValizadehOutcomes of pregnancy and glycaemiccontrol in patients with type 1 diabetesN Asatiani, R Kurashvili, M Dundua, E Shelestova,K Pagava, M Hod, S Smirnov & V VlasovCharacteristic changes of skin and itsaccessories in relation to diabetic peripheralneuropathy in patients with type 2 diabetesmellitusLR Nikoleishvili, RB Kurashvili & NG KhachapuridzeHigh risk of adrenal insufficiency after singleintra- or peri-articular steroid administration inyoung healthy sportsmenM Duclos, M Guinot, M Colsy, F Merle, JB Corcuff &Y Le BoucP728P729P730P731P732P733P734P735P736P737P738P739Capillary blood, an alternative to saliva <strong>for</strong> thediagnosis of Cushing's syndrome?N Belaidi, S Mimouni, C Ourioux, B Gatta &JB CorcuffGonadal dysfunction in male hypercortisolicsubjectsF Chentli, H Boudina, K Gati, S Azzoug &N MezianiA ras recruitment screen <strong>for</strong> glucocorticoidreceptor-interacting proteins using the entirereceptor as baitK Ecker, F Wolf, S Geley & A HelmbergHormones of cortex of adrenal glands inpatients after cardiac arrest in early postresuscitation periodA Samborska-Sablik, Z Sablik, W Gaszynski,JH Goch & K KulaClinical presentation of a patient with novelmutation in CYP17 geneLK Dzeranova, AN Tiulpakov, EA Pigarova,AV Voroncov & AM ArtemovaHypothalamic-pituitary-adrenal axis indiabetes: role of autonomic imbalanceI Chiodini, V Morelli, S Di Lembo, P Epaminonda,F Coletti, B Masserini, A Scillitani, M Arosio &G AddaEstablishing circadian rhythm profiles <strong>for</strong>salivary testosterone in women: evidence ofdecline during ageingEAS Al-Dujaili & MA SharpPrevalence of classical <strong>for</strong>ms of 21-hydroxylasedeficiency in western Siberia according to theresults of neonatal screening of congenitaladrenal hyperplasiaLA Suplotova, EB Hramova, OB Makarova,NU Yuzakova & TV BarcovaThe New Zealand white albino rabbit is asuitable model <strong>for</strong> the evaluation of 11betahydroxysteroiddehydrogenase type 1 activityin ocular tissuesCU Onyimba, P Khosla, SV Hughes, PI Murray,PM Stewart, EA Walker & S RauzAndrogen status in women withhypogonadotropic hypogonadismIA Ilovayskaya, VU Zektser, NV Latkina,NP Goncharov, EI Marova & GA MelnichenkoLong-term glucocorticoid repression of proopiomelanocortin(POMC) expressionA Eltobgi, L Abbott & J Newell-PriceA novel CYP11B2 gene mutation in an Asianfamily with aldosterone synthase deficiencyK Lovas, I McFarlane, CA Dorrian, J Schwabe,AM Wallace & VKK Chatterjeewww.ece2006.com 59POSTERS
8th European Congress of <strong>Endocrinology</strong>P740Long-term effect of flutamide, met<strong>for</strong>min andtheir combination in dieting obese womenwith polycystic ovary syndromeA Gambineri, L Patton, A Vaccina, U Pagotto &R PasqualiCan the 250mcg Synacthen test be used toscreen <strong>for</strong> primary hyperaldosteronism?K Mullan, H Leslie, B Sheridan & AB AtkinsonThe functional consequences of localglucocorticoid metabolism in synovialfibroblastsRSH Hardy, CDB Buckley, MH Hewison, LR Rabbitt& MSC CooperP752Alterations in scavenger receptor B1 andsteroidogenic enzymes within the adrenalgland in response to dietary bile acidsAD McNeilly, DEW Livingstone, SM MacKenzie,E Davies, CJ Kenyon, BR Walker & R AndrewSalivary cortisol as an alternative to serumcortisol in 1µg ACTH testK Simunkova, K Vondra, R Hampl, J Skibova,H Kazihnitkova, K Dvorakova, J Doucha & L StarkaP741P742P753P754Novel mutations in the ACTH receptor gene asa cause of familial glucocorticoid deficiencyLF Chan, LA Metherell, H Krude, JC Carel,PV DeLamater, A Huebner & AJL ClarkP743P744P745P746Challanges in paediatric Cushing's diseaseRM Fikri & P WinocourEndogenous corticosteroid synthesis insubjects after bilateral adrenalectomyM Freel, R Fraser, M Ingram, E Davies, M Wallace &J ConnellTissue specific regulation of insulin signalling:a mechanism of glucocorticoid inducedobesity?LL Gathercole, IJ Bujalska, PM Stewart &JW TomlinsonBXL-628, a vitamin D analogue, decreasesRhoA/ROK signalling in rat and humanbladderA Morelli, S Filippi, R Mancina, L Vignozzi,GB Vannelli, S Ambrosini, C Crescioli, S Donati,L Adorini & M MaggiEvaluation of aldosterone to renin ratio inpatients with adrenal incidentalomas and/orhypertensionG Efremidis, D Vassiliadi, A Sabo, A Evaggelopoulos,E Botoula, M Tzanela & NC ThalassinosP755P756P757P758Opposite effects of DHEA and DHEAS onchromaffin cell proliferationF Sicard, AW Krug, CG Ziegler, S Sperber,M Ehrhart-Bornstein & SR BornsteinThe glucocorticoid receptor 1A promoter inCD4+CD8+ thymocytes is rapidly upregulatedfollowing dexamethasone treatment in vitroJ Nixon, J Sheridan, C Blackburn & K Chapman11beta-hydroxysteroid dehydrogenase is anearly and essential marker of humanadipogenesisIJ Bujalska, LL Gatherocole, JW Tomlinson,C Darimont & PM StewartMechanisms of human prolactin regulation byoestrogenAD Adamson, S Friedrichsen, S Semprini, M Wilding,CV Harper, MRH White & JRE DavisDimerisation of the melanocortin-2 receptoraccessory protein (MRAP)MI Almiro do Vale, M Egertová, MR Elphick &AJ ClarkP747P748Prenatal diagnosis of the 'low-oestriol'disorders Smith-Lemli-Opitz syndrome (SLOS),oxidoreductase deficiency (ORD) and sulfatasedeficiency (STSD)CHL Shackleton, W Craig, W Arlt & J MarcosP759P760Expression of oestrogen receptor relatedprotein beta occurs in multiple cell typeswithin human endometrium during thenormal menstrual cycleV Bombail, T Henderson, HOD Critchley &PTK SaundersP749Corticosteroid replacement therapy - thecontroversy continues...M Freel, A Thomson, M Devers, K Campbell,D Grant, M Wallace & J ConnellP761Rapid glucocorticoid effects on insulinsensitivityBZ Beleslin, J Ciric, M Stojkovic, S Savic, Z Penezic,B Trbojevic & M ZarkovicP750Dietary polyunsaturated fatty acidsupplementation in vivo modulates ovineadrenal steroidogenesis in vitroEC Chin, JM Naddafy, Z Cheng, JS Brickell,DC Wathes & DRE AbayasekaraP762Differential regulation of Cyp4A iso<strong>for</strong>ms inmouse kidney during the development ofmineralocorticoid, salt-sensitive inducedhypertensionE Marshall, D Roy, J Mullins, C Kenyon & R BrownPOSTERSP751Human endothelial cells (HUVECs) potentiatealdosterone secretion from humanadrenocortical cells through a PKAindependentpathwayI Ansurudeen, AW Krug, S Kopprasch,M Ehrhart-Bornstein & SR BornsteinP763Glucocorticoid receptors exert a profoundanti-proliferative and anti-survival effect onhuman small cell lung cancer cellsP Le Rouzic, H Gillingham, A Berry, M Kayahara,T Huynh, P Sommer, A White & DW Ray60www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P764P765P766P767P768P769P770ThyroidP771P772P773Quantitative analysis of mifepristone(RU38486) in plasma by HPLC triplequadrupole mass spectrometryNZM Homer, GR Small, LY Ooi, H Bollina,RM Reynolds, BR Walker & R AndrewNaB affects the local regulation of vitamin D incolorectal cancerBW Ogunkolade, S Khalaf, BJ Boucher, D Davis,S Dorudi, PJ Jenkins & SA BustinBone mineral density in patients withCushing's disease. The impact of impairedglucose homeostasisM Toth, J Toke, L Futo, A Patocs, R Bertalan,P Gergics, I Varga, E Glaz & K RaczBone mineral density and its correlation withplasma cortisol concentrations in patients withinactive adrenal adenomas and in patientswith subclinical and overt Cushing's syndromeL Futo, J Toke, A Patocs, P Gergics, R Bertalan,I Varga, M Sereg, E Glaz, K Racz & M TothPhenotypic variability in P450 oxidoreductasedeficiency may be caused by differentialeffects of P450 oxidoreductase mutations onsteroidogenesisV Dhir, HE Ivison, AJ Doherty, PM Stewart & W ArltInsulin-like factor 3: a new circulating marker<strong>for</strong> the polycystic ovary syndrome-type ofovarian dysfunctionR Pasquali, L Patton, A Vaccina, R De Iasio,U Pagotto & A GambineriTranscriptional control of differentialglucocorticoid receptor expression:determining tissue specific expression andprotein iso<strong>for</strong>msJD Turner & CP MullerIn healthy women increasing TSHconcentrations within the normal range areassociated with increasing cardiovascular riskDF Waterhouse, AM McLaughlin, F Sheehan &D O'SheaA case of delayed diagnosis of pituitaryresistance to thyroid hormone (PRTH)A Nyunt & SM OrmeRelationship between sodium iodinesymporter and thyroid peroxidase expressionand cytokines production by thyrocytes frompatients with immune and non-immunethyroid disordersA Bossowski, B Czarnocka, A Stasiak-Barmuta,K Bardadin, M Urban, A Lyczkowska, J Czerwinska& J DadanP774P775P776P777P778P779P780P781P782P783P784P785The reference ranges of maternal thyroidhormones (thyrotropin and free thyroxine) atthe second and third trimesters of pregnancy:impact of FT4 assaysM d'Herbomez, G Forzy, R Sapin, D Houze del'Aulnoit, S Lepers & P CaronThe effect of high calcium on activity ofthyroid gland in ratF Ebrahimian & S Zahedi-AslSafety and efficacy of administering 0.2mg ofrecombinant human TSH <strong>for</strong> two consecutivedays as an adjuvant to low-dose radioiodinetherapy in out-patients with large non-toxicmultinodular goitreM Giusti, C Cappi, B Santaniello, E Ceresola,C Augeri, C Lagasio & F MinutoClinical aspects and diagnostics of follicularthyroid tumoursI Abesadze, I Martirosyan, EA Troshina &NV MazurinaPrevalence of thyroid dysfunction in oldresidents in the province of Pavia, northernItalyF Magri, CA Galimberti, S Chytiris, L Chiovato &E FerrariThyroid function in patients with atrialfibrillationTV Bystrova, EA Troshina, FM Abdulchabirova &LA PanchenkovaHyperthyreosis treated with thyroid arteryembolizationGW Kaminski, A Jaroszuk, K Brzozowski,A Kowalczyk, P Zukowski, Z Podgajny,P Twarkowski & M SiekierzynskiPsychological wellbeing correlates with free T4but not free T3 levels in patients on 'adequate'thyroid hormone replacementP Saravanan, T Visser & CM DayanCorrelation between endogenous thyroxineand A, G and M immunoglobulins indysthyreosisA Laszlo, I Pascanu, C Gliga, A Schiopu & M LaszloLong-term results of decompression surgery inthyroid-associated ophthalmopathyM Jern<strong>for</strong>s, M Välimäki, A Pitkäranta, K Setälä &K LaitinenFixed dose radioactive iodine therapy <strong>for</strong>hyperthyroidism: the west of IrelandexperienceJH McDermott & J O'DonnellPathogenic mutations in gene RET in patientswith medullary thyroid carcinoma found inPolish populationZ Paszko, M Sromek, M Czetwertynska,D Czapczak, A Wisniewska, E Skasko, I Kozlowicz-Gudzinska, A Prokurat & M Chrupekwww.ece2006.com 61POSTERS
8th European Congress of <strong>Endocrinology</strong>P786Epidemiology of endemic goiter in mountainregion of Adjara Autonomy Republic (Georgia)N Sekhniashvili, R Kvanchakhadze, D Tsereteli,Z Sekhniashvili & L BaramidzeP798Thyroid disease prevalence and incidence in aDutch population surveyA Roos, TP Links, SJL Bakker <W de Jong-van den BergPOSTERSP787P788P789P790P791P792P793P794P795P796P797Epidemiologic analysis of thyroid fine needleaspiration biopsies over a period of 18 years(1987-2004)S Polyzos, M Kita, DG Goulis, A Benos, N Flaris,M Leontsini & A AvramidesDifferentiated thyroid carcinoma - experiencesfrom a centre in South IndiaK Sudeep, N Thomas, M Seshadri, S Anjali,R Oommen & TV PaulUltrasound thyroid changes: Moscowpopulation screening resultsEA Troshina, NV Mazurina, NV Galkina &IT MartirosyanQuality of life, health status, symptoms andtreatment satisfaction in subclinicalhypothyroidism: a double-blind 12-weekcross-over study of L-thyroxine versus placeboS Razvi, CV McMillan & JU WeaverLoss of heterozygosity and genetic associationanalyses within 11q13.5-q14 chromosomalregion in papillary thyroid carcinomaR Ramirez-Lorca, E Ferrero Herrero, ME Saez,M Labalde Martinez, LM Real, A Ruiz & M HidalgoPascualEnvironmental and socio-economic risk factorsof thyroid cancer in Olsztyn and the Warmiaand Mazury region, PolandE Bandurska-Stankiewicz & E Aksamit-BialoszewskaReverse transcriptase (RT) inhibitors downregulate tumor growth, induce celldifferentiation and re-establish iodine uptakein human thyroid anaplastic carcinoma in vitroand in vivoM Landriscina, A Fabiano, S Altamura, C Bagalà,A Piscazzi, N Maiorano, F Giorgino, C Barone &M CignarelliThe effect of block and replacement regimefollowing radioiodine therapy <strong>for</strong>thyrotoxicosis on thyroid function in the postradioiodineperiodB Vaidya & S EstcourtPrevalence of amiodarone-induced thyroiddisorders in iodine deficiency regionSI Ismailov, NL Kayumova & N AbdusalamovaCorrection of oxidative metabolism inmyocardium by oligocrine duringexperimental thyrotoxicosisM Kvirikashvili, T Sanikidze & D MetreveliThe metabolic syndrome and the thyroid ineuthyroidismA Roos, SJL Bakker, TP Links & BHR WolffenbuttelP799P800P801P802P803P804P805P806P807P808P809P810Increased lipid peroxidation in critically illpatients with low-T3 syndromeM Karbownik, A Kokoszko, M Jozefiak & A LewinskiAsymmetric dimethyl arginine levels in thyroiddysfunctionsE Arikan, CH Karadag & S GuldikenResults of fine-needle aspiration biopsy ofthyroid nodules in region of mild iodinedeficiencyD Metreveli & K MikadzeThyroid cancer: diagnostic role of ultrasoundand ultrasound-guided fine needle aspirationbiopsy (US-FNAB) evaluationV Triggiani, E Guastamacchia, F Resta, C Sabba &E TafaroParathyroid hormone determination in fineneedle aspirates (PTH-FNAB) allows thedifferentiation between thyroid andparathyroid lesionsV Triggiani, E Guastamacchia, F Resta, C Sabba &E TafaroHeart rate variability in thyroidectomizedpatients using suppressive therapy withthyroxineAV Kovalchuk, ST Zubkova & VN KovalchukClinical value of the assessment of neopterinin Graves' ophthalmopathyA Baldys-Waligorska, B Kusnierz-Cabala,E Placzkiewicz-Jankowska & B HusznoMaternal iodine deficiency alters learningability and emotional state of the progenyA Sarishvili, N Lazrishvili & D MetreveliQuantitative and qualitative evaluation of theimpact of a ten-year iodine interventionprogramme in rural areas of TehranN Salarkia, F Rabiee & F AziziEffect of oral administration of propylthiouracilduring pregnancy and lactation period onisolated aorta response of their adult maleoffspringS Zahedi, M Khaksari, M Shafiee & A GasemiStudy of the prevalence and mechanisms ofaction of TSH receptor and Gs protein alfasubunitmutations in toxic multinodular goiterand toxic adenoma in Galicia (Spain)F Palos, O Perez, V Alvarez-Iglesias, J Cameselle,F Barreiro, D Araujo, R Argueso, M Botana,JM Cabezas, L Dominguez, T Martinez, J Nuño,JC Rueda & J Lado-AbealThe relationship between echocardiographicleft atrial size and atrial fibrillation in patientswith Graves' diseaseIA Vaychulis & II Shaposhnik62www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P811P812P813P814P815P816P817P818P819P820P821P822ClC-5 does not affect megalin expression andfunction in the thyroid glandS Lisi, T Maritzen, R Botta, A Pinchera, C Marcocci,TJ Jentsch & M MarinòRAP (LDL receptor-associated protein)expression in thyroid epithelial cells: evidence<strong>for</strong> TSH-dependence in vivo and in vitroR Botta, S Lisi, A Pinchera, C Segnani, L Cianferotti,MA Altea, F Menconi, L Mattii, GU Corsini,C Marcocci, A Dolfi, N Bernardini & M MarinòLiver enzyme alterations during high doseintravenous glucocorticoid pulse therapy <strong>for</strong>Graves' ophthalmopathy: frequency andputative risk factorsMA Altea, E Morabito, F Menconi, R Piccione,F Latrofa, B Mazzi, L Bartalena, A Pinchera,C Marcocci & M MarinòHigh-intensity focused ultrasound (HIFU)treatment <strong>for</strong> thyroid nodules: first clinicalstudyOE Esnault, BF Franc, FM Ménégaux, AR Rouxel,EDK Kerviller, PB Bourrier & LL LeenhardtDigital infra-red orbital thermography in theassessment of thyroid eye diseaseSE Williams, AR Hill & BW FleckPrognostic factors <strong>for</strong> persistent or recurrentdisease from a series of 81 patients withoncocytic thyroid carcinomaCD Cao, H Mirghani, JL Wemeau, E Leteurtre,M D'Herbomez, X Marchandise & C ProyeAssociation of CTLA-4 exon 1 polymorphismwith Graves' disease in Spanish patientsP Álvarez-Vázquez, D Valverde, L Constela, L PérezMéndez & RV García-MayorReference intervals of maternal free thyroxine(FT4) at the second and third trimesters ofpregnancy using the Beckman Coulter's AccessFree T4 assayV Jarrige, H Meurisse & M D'HerbomezBioavailability of iodine bound in humicsubstances in drinking water and the impacton thyroid functionS Andersen, P Gustenhoff, F Iversen, S Terpling,KM Pedersen & P LaurbergApplication of positron emission tomography(PET) in the study of cerebral glucose uptakein hypothyroid rats: effect of T3 administrationM De Servi, N Belcari, J Bernal, S Refetoff,P Salvadori, E Gianetti, G De Marco, M Tonacchera,P Vitti, A Del Guerra & A PincheraThe development of a symptom-based clinicalactivity score <strong>for</strong> thyroid eye diseaseCE Elder, BW Fleck & S RajackA qualitative study of patients' experience ofthyroid eye diseaseCE Elder & BW FleckP823P824P825P826P827P828Etiology of congenital hypothyroidism inchildren with a normal located thyroid glandC Di Cosmo, M Tonacchera, G De Marco, P Agretti,ME Banco, A Perri, H Ramos, C Ceccarelli, P Vitti &A PincheraClinical characterisation and genetic analysis ofa large euthyroid family with TSH-receptorgermline mutation (N372T) and ahyperthyroid index patient with an additionalsomatic TSH-receptor mutation (S281N) onthe second TSH-receptor alleleHI Gozu, R Bircan, K Krohn, S Müller, D Yavuzer,G Ekinci, H Sargin, M Sargin, E Orbay, B Cirakoglu& R PaschkeEstimation of the optimal diagnostic complexof the treatment of the nodular euthyroid<strong>for</strong>mations of thyroidV Chachibaia, B Gvadzabia, E Giorgadze &K MirianashviliThe diagnostic value of Dopplerultrasonography in determining themalignancy potential of thyroid nodulesF Sahin, M Varer, A Sarsilmaz, G Oruk, M Apaydin& E UlucFavourable outcome of Graves'ophthalmopathy (GO) after glucocorticoids(GC) in patients treated with total thyroidablation (TTA): results of a randomized clinicaltrialFM Menconi, MM Marinò, LB Bartalena, RR Rocchi,MN Nardi, AP Pinchera & CM MarcocciLipids profile and carotid scan atheroscleroticparameters in newly diagnosed hypothyroidfemalesVP Popovic-Radinovic, ZG Gluvic, MV Vujovic,JT Tica, ZR Rasic-Milutinovic, DM Milicevic,EI Isenovic & MP PavicevicP829 Safety of pharmacological treatment of thyroiddiseases during pregnancyE Gianetti, M Tonacchera, L Russo, A Perri, P Vitti &A PincheraP830 Increase of L-thyroxine requirement duringpregnancyL Russo, M Tonacchera, E Gianetti, A Perri, P Vitti &A PincheraP831 Congenital thyroid hemiagenesis in associatonwith multinodular goitre - a case reportM Varer, A Sarsilmaz, G Oruk, H Akin, M Apaydin& E UlucP832 Insulin-like growth factor-I counteracts 131 I-induced thyroid stunning by stimulating thetranscription of the sodium/iodide symporter(NIS)M Nordén, C Johanson, S Tedelind, F Larsson,T Carlsson & M NilssonP833 A case of Riedel's thyroiditis successfullytreated with glucocorticoidsG Viccica, T Rago, P Berti, A Pinchera & C Marcocciwww.ece2006.com 63POSTERS
8th European Congress of <strong>Endocrinology</strong>POSTERSP834P835P836P837P838P839P840P841P842P843P844An audit of radioiodine treatment <strong>for</strong>thyrotoxicosis in CambridgeH Andreou, S Kalavalapalli, M Gurnell, H Simpson,DF Wood, KK Balan & VKK ChatterjeeOn-levothyroxine measurement ofthyroglobulin is not a reliable screening test<strong>for</strong> patients at high risk of remnant/recurrentdifferentiated thyroid carcinomaA Gholamrezanezhad, M Saghari, S Mirpour &D BeikiPrevalence of somatic TSHR and Gs alphamutations in toxic thyroid nodules (TTNs) inendemic and non-endemic goiter areas ofTurkeyHI Gozu, R Bircan, K Krohn, S Müller, S Vural,C Gezen, H Sargin, M Sargin, B Çirakoglu &R PaschkeThe role of autoimmunity and thyroid functionon pregnancy outcomes in euthyroid womenwith autoimmune disease undergoing assistedreproductionR Negro, G Formoso, L Coppola, G Presicce,T Mangieri, A Pezzarossa & D DazziValue of routine measurement of serumcalcitonin concentrations in patients withnodular goiter: a multicenter studyG Papi, SM Corsello, K Cioni, AM Pizzini, S Corrado,C Carapezzi, G Fadda, A Baldini, C Carani,A Pontecorvi & E RotiAssociation between patient- and tumorrelatedfactors and the gene expression profileof papillary thyroid cancerS Szpak-Ulczok, M Wiench,M Oczko-Wojciechowska, J Wloch, K Fujarewicz,A Swierniak, D Lange & B JarzabLevothyroxine suppressive therapy in thyroidnodulesS Azzoug, K Maachi & F ChentliLevothyroxine suppressive therapy and bodycompositionS Dubois-Ginouves, S Laboureau-Soares Barbosa,JF Dumas, P Abraham, A Sallé, F Illouz, P Rodien,P Ritz & V RohmerDifferential regulation of soluble Fas inpatients with autoimmune thyroid diseaseS Fountoulakis, N Kolaitis, G Philippou,G Vartholomatos & A TsatsoulisApplication of new technology of anti-DNAantibodies detection in diagnostics ofautoimmune thyroiditisG Vagapova, L Anchikova, O Konovalova,L Sattarova, E Podshivalina, V Vinter & M SalahovThyroxine replacement dose in patients withHashimoto disease: a potential role <strong>for</strong>interleukin-6NP Papanas, DP Papazoglou, KP Papatheodorou,LP Papazoglou, TE Exiara, MB Bitsakaki, SK Kotsiou& EM MaltezosP845P846P847P848P849P850P851P852P853P854P855P856P857The glutathione peroxidase 3 promoter isactivated by Pax8B Mentrup, N Renault, C Schmutzler & J KöhrleSimilarities in the role of FoxE1 in thyrocytesand keratinocytes?M Bullock, M Jehani, P Bowden & M LudgateInhibin B/inhibin binding protein complex isdifferentially expressed in normal and nodularhuman thyroid tissueM Della Guardia, A Franchi, S Nardo,MG Santaguida, R Sibilla & M CentanniTowards the development of a valid quality oflife questionnaire <strong>for</strong> patients with thyroiddiseases: which questions shall we ask?T Watt, M Groenvold, AK Rasmussen, SJ Bonnema,L Hegedüs, JB Bjorner & U Feldt-RasmussenThe efficacy of levothyroxine therapy in thenontoxic multinodular goiterAM Mihai, AE Ranetti, C Spiroiu, A Mazilu &C RanettiAssociation of the FCRL3 gene with Graves'disease in the UK Caucasian populationMJ Simmonds, JM Heward, J Carr-Smith, JAFranklyn & SCL GoughTreatment options in progressive medullary,follicular, and papillary thyroid carcinomas:evaluation of chemotherapy with doxorubicinA Matuszczyk, A Bockisch, P Veit, K Mann &S PetersennStaging of progressive papillary, follicular, ormedullary thyroid carcinomas: comparison ofvarious staging procedures to define theextent and progress of diseaseA Matuszczyk, S Petersenn, A Bockisch, S Sheu,P Veit & K MannThe effect of obesity and weight loss onthyroid hormone statusL Keskin, I Sahin, R Bentli, S Senel & C TaskapanThe research of IQ level in school childrenwho live in the regions with iodine deficiencySL Slovjeva, A Troshina & AO ZhukovUnmasking of central hypothyroidismfollowing growth hormone replacement inadult hypopituitary patientsA Agha, D Walker, WM Drake, SL Chew,AB Grossman, PJ Jenkins & JP MonsonSomatostatin receptor scintigraphy with99mTc-HYNIC-TATE in visualization of nonradioiodine-aviddifferentiated thyroidcarcinomaZ Podgajny, G Kaminski, N Szalus, A Kowalczyk,J Pietrzykowski, A Jaroszuk & M SiekierzynskiA novel test with recombinant human TSH <strong>for</strong>the differential diagnosis of congenitalhypothyroidism in pediatric ageL Fugazzola, G Weber, D Mannavola, G Vannucchi,M Carletto, V Longari, L Persani & P Beck-Peccoz64www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P858P859P860P861P862P863P864P865P866P867P868P869The use of recombinant human thyrotropin(rhTSH) in amiodarone-inducedhyperthyroidismZ Adamczewski, J Makarewicz, M Knapska-Kucharska, L Oszukowska, A Karwowska &A LewinskiThyrotropin receptor (TSHR) activation hasvariable effects on the TNF alpha axis inpreadipocytes and osteoblast-like cell linesM Mandrikoula, M Henry, BAJ Evans & M LudgateFollicular and Hürthle thyroid nodule atcytology: diagnostic value of nuclear atypiacell neoplasiaT Rago, G Di Coscio, F Basolo, M Scutari, P Berti,R Romani, P Faviana, P Miccoli, A Pinchera & P VittiThe use of Konjac glucomannan to lowerserum thyroid hormones in hyperthyroidismT Bayraktaroglu, F Kutluturk, A Azezli, Y Orhan &S TanyolacComparison of the effects of thyrotropinreceptor (TSHR) activation on preadipocytecell lines from white (WAT) and brown (BAT)adipose tissueL Zhang, C Paddon, GC Baker & M LudgateEffects of increment of endogenous TSH levelson the effective half-life time of 131 I and iodineuptake by thyroid remnants in patients afterthyroidectomyM Knapska-Kucharska, J Makarewicz,L Oszukowska, Z Adamczewski & A LewinskiSurgery should be considered equally with 131 Iand thionamide treatment as first line therapy<strong>for</strong> thyrotoxicosisT Sathyapalan, SL Atkin & RJA EnglandThyrotoxicosis - a risk factor <strong>for</strong> subsequentdevelopment of osteoporosis?T Zimmermann-Belsing, B Langdahl, P Charles &U Feldt-RasmussenRelationship between cardiac arrhythmias andsubclinical hyperthyroidismP De Remigis, L Vianale, A De Remigis, P Sabatini &E Di GirolamoCardiovascular disease in patients with andwithout hypothyroidismC Neves, JL Medina & F LopesClinical parameters and echographic patternsare poor predictors of malignancy in follicularand Hürthle cell nodules at cytologyT Rago, G Di Coscio, F Basolo, M Scutari, P Berti,R Romani, P Faviana, P Miccoli, A Pinchera & P VittiIdentification of housekeeping genes useful <strong>for</strong>the normalization of RNA in studies of geneexpression in thyroid carcinomasP Piampiani, C Romei, B Cosci, A Vivaldi, R Ciampi,A Pinchera & R EliseiP870P871P872P873P874P875P876P877P878P879P880Identification of a novel germ-line pointmutation of the RET gene (Met848Thr) in apatient affected by medullary thyroidcarcinoma and Castleman's syndromeB Cosci, M Altea, M Castagna, C Romei,P Piampiani, A Vivaldi, R Ciampi, P Faviana,F Basolo, A Pinchera & R EliseiUsefulness of molecular analysis of BRAFmutation and RET/PTC rearrangements in fineneedle aspiration (FNA) of thyroid noduleswith non-diagnostic cytologyC Romei, T Rago, M Scutari, V Bottici, G Di Coscio,F Basolo, P Berti, A Pinchera, P Vitti & R EliseiDoes selenium deficit trigger post partumthyroiditis?HG Bohnet17-AAG and DIDS increase the iodideretention time in thyroid cancer cellstransfected with NISA Vivaldi, R Ciampi, F Santini, B Cosci, P Piampiani,C Romei, A Pinchera & R EliseiDemethylating treatment with azacytidineinduces retinoic acid receptor RAR betaexpression in human thyroid cancer cellsFY Miasaki, A Vivaldi, R Ciampi, L Agate, B Cosci,P Piampiani, C Romei, A Pinchera & R EliseiFree thyroxine (FT4) is the analyte of choice inearly gestationB Dando, R Taylor, R Henley, AB Parkes, R John &JH LazarusComparison of TPOAb assays in earlypregnancyR Henley, AB Parkes, L Taylor, R John & JH LazarusAge and gender differences and phenotypesof patients with autoimmune thyroid disease -the UK AITD consortiumJD Carr-Smith, N Manji, K Boelaert, A Allahabadia,M Armitage, J Lazarus, S Pearce, B Viadja,SC Gough & JA FranklynInfluence of family history on the age ofpresentation of AITD - the UK AITDconsortiumN Manji, JD Carr-Smith, K Boelaert, A Allahabadia,M Armitage, J Lazarus, S Pearce, B Viadja,SC Gough & JA FranklynPrevalence of thyroid dysfunction and otherautoimmune disorders within the families ofsubjects with autoimmune thyroid disease -the UK AITD consortiumN Manji, JD Carr-Smith, MJ Simmonds,A Allahabadia, M Armitage, J Lazarus, S Pearce,B Viadja, JA Franklyn & SC GoughDo SNPs within the PTPN22 gene contributeto autoimmune disease via differentmechanisms?J Heward, M Simmonds, JA Franklyn & SC Goughwww.ece2006.com 65POSTERS
8th European Congress of <strong>Endocrinology</strong>POSTERSP881P882P883P884P885P886P887P888P889P890P891P892Screening of autoimmune thyroid disorders inpregnancy in a highland districtJ Horacek, S Spitalnikova, J Cepkova, V Ceeova,J Dolezal, J Vizda & J MalyGene expression profile in functioning andnon-functioning nodules of autonomousmultinodular goiters from an area of iodinedeficiencyP Agretti, G de Marco, M de Servi, E Gianetti,F Basolo, A Pinchera, P Vitti & M TonaccheraComparison of efficiency of iodine-prophylaxisin healthy pregnant women and pregnantwomen with non-toxic goiter, living in aregion with mild iodine-deficiencyTPS Shestakova, AVD Dreval & OAN NechaevaGene expression profile in orbital fibroblastsfrom a TAO patient be<strong>for</strong>e and afteradipocytic differentiationP Agretti, G de Marco, E Ferrarini, A Dimida,D Sansone, M Banco, M de Servi, S Lisi, C Marcocci,M Marinò, P Vitti, A Pinchera & M TonaccheraIs subclinical hyperthyroidism associated withblood pressure and hypertension?H Völzke, M Dörr & H WallaschofskiThyrotoxicosis in childhood. UK and IrelandSurveillance Study 2004-2005SM Williamson & SA GreenePKA II mediates cAMP-dependentphosphorylation of CREB and activation ofgene transcription in differentiated rat thyroidcellsD Calebiro, T de Filippis, S Lucchi, P Porrazzi,P Beck-Peccoz & L PersaniTranscriptomic analysis of the oncocytic signalin vesicular thyroid tumoursJF Fontaine, F Savagner, M Melo, B Ballester,R Houlgatte & Y MalthièryApplication of MRI in the differential diagnosisof different <strong>for</strong>ms of Hashimoto's thyroiditis inpatients from the iodine deficient regionG Vagapova & I MikhailovImmunohistochemical staining <strong>for</strong> thyroidperoxidase (TPO) of TRU-CUT biopsies fromscintigraphically cold thyroid nodulesU Yousaf, L Christensen, AK Rasmussen, F Jensen,E Hilmer, C Mollerup, J Kirkegaard, I Lausen &U Feldt-RasmussenRegulation of fibroblast growth factorreceptor-1 (FGFR1) by thyroid hormone (T3):identification of a thyroid hormone responseelement (TRE) in the murine Fgfr1 promoterPJ O'Shea, GR Williams & SY ChengSubclinical hypothyroidism - how soon totreat?S Ghita, M Musat, M Simescu, E Balmes, H Ursu,C Badiu & G TotoianuP893P894P895P896P897P898P899P900P901P902P903Cytostatic effect of plitidepsin (aplidintm) inhuman undifferentiated (anaplastic) thyroidcarcinomaS Bravo, M Garcia-Renduelles, R Seoane, V Dosil,J Cameselle, L Lopez-Lázaro, J Zalvide, F Barreiro,C Pombo & C AlvarezA case of severe thyrotoxic hypercalcaemiaVKB Prabhakar & PJ HaleEfficacy of high dose radioiodine in thetreatment of elevated serum thyroglobulin inpatients with differentiated thyroid carcinomaand negative whole body iodine scanA Gholamrezanezhad, M Saghari, S Mirpour,D Beiki & B FallahiIsometric tension studies in a transgenicmouse model of thyroid hormone resistancePJD Owen, D Tomlinson, H Ying, D Lang, SY Cheng& JH LazarusThe GH response to ghrelin in humans isreduced in conditions of hyper- andhypothyroidismF Broglio, F Prodam, F Riganti, E Gramaglia,R Rossetto, M Maccario & E GhigoMulticenter evaluation of the Abbott Architectanti-Tg and anti-TPO assaysR Anarat, C Bena, H Garth, M Klein, A Radicioni,S Schmitt, C Smith, S Szepanski, M Turanchik &J WaterstonAutoantibody profile in patients with Graves'disease and thyroid-associatedophthalmopathyNV Latkina, IA Ilovayskaya & IV KryukovaTreatment of disseminated non-radioiodine-AVID papillary thyroid cancer with 90Y-DOTA-TATE preparationN Szalus, G Kaminski, K Obuchowski,J Pietrzykowski, Z Podgajny, M Zagrodzka &E DziukHashimoto's thyroiditis in the children. Clinicalfeatures at presentationVT Skarpa, ED Kostakioti, AK Tertipi, PA Petrou,E Posnaghidou, M Anastasakou, P Papahilleos,A Papathanasiou & C HadjiathanasiouCorticotherapy alone or corticotherapycombined with orbital radiotherapy in severeactive Graves' ophthalmopathy: therapeuticoutcome in 905 patientsH Jastrzebska, M Gietka-Czernel, J Janik,S Zgliczynski, R Karczmarzyk & J FijuthThe effects of treatment with L-thyroxine onlevel of prolactin, CRP and insulin inpremenopausal women with subclinicalhypothyroidismZ Velija-Asimi & B Heljic66www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>P904P905P906P907P908P909P910P911P912P913Modifications in the frequency of presentationand the TNM stage at diagnosis of thyroidcarcinoma in the last decade in Valencia(Spain)J Yanini, R Casañ, K García, A Jover, M Gómez,E Solá, C Morillas, H Peña, ML Muñoz &A HernándezPretreatment with rhTSH allows effective 131 Itherapy in patients with multinodular toxicgoiter and low radioiodine uptakeM Gietka-Czernel, H Jastrzebska, W Zgliczynski,G Wasniewska, M Wróblewska, K Wernic,B Cybulska & E KarpińskaRepression of the human NIS upstreamenhancer (hNUE) by PTTGVE Smith, K Boelaert, AL Strat<strong>for</strong>d, SR James,R Susarla, T Kogai, MC Eggo, JA Franklyn &CJ McCabeComparison of cytogenetic damage inpatients with differentiated thyroid cancerreceiving ablative 131 I therapy in thehypothyroid status versus the euthyroid status(rhTSH assisted treatment)A Frigo, G Francia, MV Davi, G Boni, C Traino,L Scilanga, F Bernardi, G Mariani, A Vaiano,C Colato, V lo Cascio & M FerdeghiniCorrection of hypomagnesaemia improves thesymptoms of hypocalcaemia afterthyroidectomyMFA Abdelhamid, MS Barsoum, SA Shaheen &LA MansourThe thyroid gland and its selenoenzymes arepreferentially supplied in selenium-deficienttransgenic miceL Schomburg, C Riese, M Michaelis, E Griebert,MO Klein, R Sapin, U Schweizer & J KoehrleChanges in thyroxine requirement in the longtermfollow-up of hypothyroid patientsAK Viswanath, A Avenell, S Philip, S Acharya,G MacLennan, K Dalziel, SA Copland, JS Bevan &P AbrahamProblems of identifying independent non-classII susceptibility loci within the HLA region <strong>for</strong>Graves' diseaseMJ Simmonds, JM Heward, JA Franklyn &SCL GoughIs 131 I therapy <strong>for</strong> hyperthyroidism harmful <strong>for</strong>testis function?C Ceccarelli, D Canale, E Fiore, C Moschini,C Caglieresi, P Vitti & A PincheraWhat is the most effective screening interval inthe long-term follow-up of stable hypothyroidpatients on thyroxine?AK Viswanath, A Avenell, S Philip, S Acharya,G MacLennan, K Dalziel, O Pereira, SA Copland,JS Bevan & P AbrahamP914 Expression and signal transduction of thecAMP-binding protein Epac in thyroid cellsand thyroid tumorsM Broecker-Preuss, S-Y Sheu, J Baten, M Bollepalli,M Schmidt, KW Schmid & K MannP915 Orbital tissue expansion expressed as anumber: usefulness in grading the severity ofthyroid-associated ophthalmopathy (TAO)GM Vannucchi, I Campi, S Avignone, AM Minetti,C Guastella, F Sbrozzi, P Beck-Peccoz & M SalviP916 Radioiodine treatment <strong>for</strong> hyperthyroidism -do Royal College guidelines suggest too higha radioiodine dose?R Zakir Ahmed & J P HoskerP917 Thyroid cancer management: are guidelinesbeing met?HS Chahal, S Velmurugan, SA Mellish, R Lewis,KA Metcalfe & JA AhlquistP918 Treatment of patients with Graves' disease andophthalmopathy with the anti-CD20monoclonal antibody rituximabM Salvi, GM Vannucchi, I Campi, C Guastella,F Sbrozzi, S Simonetta, S Rossi, P Bonara,S Avignone & R RatigliaP919P920P921P922P923P924P925Withdrawal of alfacalcidol supplementsfollowing thyroidectomy: baseline plasma PTHpredicts successful outcomeM Morris & P PerrosTreatment of pretibial myxedema withdexamethasone injected subcutaneously bymesotherapy needlesI Campi, GM Vannucchi, L Forzenigo, P Beck-Peccoz& M SalviRadioiodine uptake test reduces duration ofrestrictions following radioiodine therapy <strong>for</strong>management of hyperthyroidismVN Cherukuri, M Edavalath, N Iqbal, SL Ryan,BM Singh & HN BuchThe distance between histotypes ofdifferentiated thyroid cancer: gene expressionprofiling studyB Jarzab, J Wloch, D Lange, M Oczko-Wojciechowska, E Chmielik, A Czarniecka,M Kowalska, K Fujarewicz, K Simek, G Gala &A SwierniakThe risk of hypercholesterolemia in patientswith subclinical hypothyroidismL Marina, Z Penezic, S Vujovic, M Stojanovic,M Ivovic & M DrezgicAudit of management of hypothyroidism in ajoint endocrine/antenatal clinicN Batra, E Ferriman & PE BelchetzThyrotoxicosis is coupled with quantitativeand qualitative sleep disruptionsF Riganti, F Prodam, E Gramaglia, E van Cauter,E Ghigo & F Brogliowww.ece2006.com 67POSTERS
8th European Congress of <strong>Endocrinology</strong>P926The Gods placed the diagnosis be<strong>for</strong>e thetherapy: case reports of the Slovak familieswith resistance to thyroid hormonesP Vanuga, E Mendelova, G Fodor, K Vitesnik,F Savagner, Y Malthiery & M PuraEpidemiology of thyroid cancer in Republic ofSakha during 1970-2001A Makarov, E Makarova, V Argunov & F IvanovaP940Further results of treatment and outcomes inpatients with subacute thyroiditis observed inthe period from 1993 to 2005LA Kabelnitskaya, EB Petrova, N Platonova &EA TroshinaAge related changes of soluble Fas, Fas ligandand Bcl-2 in autoimmune thyroid diseasesJK Mysliwiec, M Oklota, A Nikolajuk & M GorskaComparison of radioiodine with radioiodineplus lithium in the treatment ofhyperthyroidismK Ahmed, GMK Nijher, A Banerjee,J Frank & K MeeranP927P941P928P929P930Rate of decrease in anti-thyroid antibody levelsafter therapeutic intervention in patients withthyroid cancerD Thomas, I Kostoglou-Athanassiou, E Vassiliou,V Liakos, N Mytakidis, F Chatzimarkou,P Athanassiou & P KaldrymidisFuther results of treatment and outcomes inpatients with subacute thyroiditis observed inthe period from 1993 to 2005EV Petrova, NM Platonova, LA Kabelnitskaya &EA TroshinaCowden syndrome - a clinical entity to beaware ofO Schmiedel, K Becker & JK PlattsFine-needle aspiration biopsy of thyroidnodulesS Radenkovic, M Pes˘ic, R Kocic, D Dimic,D Mikic & M Velojic GolubovicP942P943P944Monitoring of goiter and urinary iodineexcretion in 6- to10-year-old school childrenin Ahvaz (2003-2004)H Shahbazian & S SaiediniaPrevalence of subclinical dysfunctions ofthyroid gland in women older than 40 yearsS Glonti, L Jashi, G Tsetskhladze & T RukhadzeP931P932Palpation versus ultrasonography-guided fineneedleaspiration biopsy of thyroid nodules inendemic goiter areaBK Koroglu, N Tamer, M Koroglu, NE Gulcelik &O AksuP933Thyroid storm induced cardiomyopathy isreversibleNM Neary, AEC Fountain, ECI Hatfield, KF Fox &K MeeranP934Medullary thyroid carcinoma - which test isthe best?D Ciobanu, C Vulpoi, B Galusca, L Andriescu,A Grigorovici, C Cristea, V Mogos, MS Mihailovici &E ZbrancaGlutamic acid decarboxylase (GAD) and antityrosinephosphatase (IA2) antibody positivityin newly-diagnosed Graves' disease patientsA Harmanci, M Bayraktar, G Hascelik & A GurlekP935P936Hyperthyroidism presenting as ventricularfibrillationLR Chilukuri, Z Merza & TH JonesP937Heart rate dynamics in hyperthyroidismJ-L Chen, Y-J Tseng & W-C ChuP938Impact of TNM classification categories onthyroid gland carcinomaP Sykorova, P Vlcek, L Jirsa & K PersonovaAntiproliferative effects of SOM230 on orbitalfibroblasts from active Graves'ophthalmopathyD Pasquali, V Rossi, G Bellastella, D Esposito,MC Quinto, A Bellastella & AA SinisiPOSTERSP93968www.ece2006.com
FHFHF.P.F.P.FHFHFH8th European Congress of <strong>Endocrinology</strong>Floor Plan – Hall 3EmergencyExitVehicle AccessDoor 3.3F.P.EmergencyExitVehicle AccessDoor 3.2FHF.P.F.P.EmergencyExitVehicle AccessDoor 3.12928272536Seating Area42 39344140 332632243138 2235233021 1920REG DESKF.P.Exit / EntranceCatering18STORAGE16REG DESK179 1015 12 114 13REG DESKEmergencyExit / Entrance811STORAGERegistration Area6REG DESK2 3547F.P.Exit / EntranceFHKIOSKKEEPCLEARF.P.KIOSKF.P.ROLLER SHUTTER ROLLER SHUTTERS ROLLER SHUTTERSF.P.PRIVATEEmergencyExit DoorsExhibitors1 Pfizer Endocrine Care2 International Journal of<strong>Endocrinology</strong> and Metabolism3 European <strong>Society</strong> of<strong>Endocrinology</strong>4 S Karger Publishers5 LINCO Research6 Internet caféKINDLY SUPPORTED BY ORGANON7 GlaxoSmithKline8 Novartis9-11 Novo Nordisk12-15 Ipsen Ltd16-17 Eli Lilly18 BioSource19 Ardana20 <strong>Society</strong> <strong>for</strong> <strong>Endocrinology</strong>/BioScientifica Ltd21 Schering Healthcare22 Roche23 Ferring Pharmaceuticals24 British Thyroid Foundation25 AACE26 Thyroid Eye Disease27 The Endocrine <strong>Society</strong>28 ECE 200729 EASO30 Pituitary Foundation31-32 Genzyme33 IDS34 Shire Pharmaceuticals35 Addisons Disease Self-Help Group36 Wisepress38 AMEND39 HRA Pharma40 Turner Syndrome Support <strong>Society</strong>41 Glasgow Convention Bureauwww.ece2006.com 73EXHIBITORS AND SPONSORS
8th European Congress of <strong>Endocrinology</strong>Exhibitors and SponsorsGold sponsorsIpsen Ltd Novartis Pharmaceuticals PfizerBronze sponsorsEli Lilly Novo Nordisk RocheExhibitors and sponsorsEXHIBITORS AND SPONSORSAddison’s Disease Self-HelpGroupAMENDAmerican Association ofClinical EndocrinologistsArdanaBioSourceBritish Thyroid FoundationECE 2007The Endocrine <strong>Society</strong>European <strong>Society</strong>of <strong>Endocrinology</strong>European Association<strong>for</strong> the Study of ObesityFerring PharmaceuticalsGenzymeGlasgow Convention BureauGlaxoSmithKlineHRA PharmaIDSInternational Journal of<strong>Endocrinology</strong> and MetabolismLINCO ResearchOrganon LaboratoriesPituitary FoundationS Karger PublishingSchering HealthcareShire Pharmaceuticals<strong>Society</strong> <strong>for</strong> <strong>Endocrinology</strong>and BioScientifica LtdThyroid Eye DiseaseTurner SyndromeSupport <strong>Society</strong>Wisepress74www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>Exhibitor and Sponsor Profiles - continued• We screen about 65 million compounds every year inour search <strong>for</strong> new medicines• We supply one quarter of the world's vaccines• We have protected more than 85 million people fromlymphatic filariasis (elephantiasis) with GSK-donatedalbendazole• In 2004 we shipped more than 33 million tablets ofpreferentially-priced Combivir (our HIV treatment) toAfrica• More than 100 countries have benefited from ourhumanitarian product donations• We produce over 600 million tubes of toothpaste everyyearGenzymeSTANDS 31-32Thyrogen (thyrotropin alfa) is therecombinant human thyroidstimulating hormone (rhTSH), developed by Genzyme (ahighly diversified global health care biotech company)<strong>for</strong> use in patients with well-differentiated thyroid cancerwho have had their thyroid gland removed. Thesepatients must take thyroid hormone suppression therapy(THST) and undergo periodic testing <strong>for</strong> recurrent ormetastatic cancer. Thyrogen allows patients to remainon their THST and avoid the debilitating symptoms ofclinical hypothyroidism.4620 Kingsgate, Cascade Way, Ox<strong>for</strong>d Business ParkSouth, Ox<strong>for</strong>d, OX4 2SU, UK (Tel: +44 -1865 -405-217,Fax: +44 -1865 -402-964, Website: www.genzyme.com)HRA PharmaSTAND 39Laboratoire HRA Pharma commercialises pharmaceuticalproducts that fulfil unmet medical needs. The companyidentifies and develops its products using its own internalresources and through collaborative endeavours withpublic research institutions. It focuses primarily on women'sand reproductive health and oncology, but is open to otheropportunities that fit within its overall mission.HRA Pharma was founded in 1996 by two experiencedprofessionals from the pharmaceutical industry. Between1995 and 1999 the company's founders, in collaborationwith a small but experienced team, worked to developseveral products. This work was entirely financed by thefounders' own personal resources and contributions fromprivate investors.The company's first product, NorLevo emergencycontraception, was launched in France in May 1999.NorLevo generated such strong interest among keyplayers in public health that French health authoritiestook measures to make it more readily available. As aresult, NorLevo became the first hormonal contraceptiveavailable without a medical prescription in France, andthe only contraceptive available free of charge <strong>for</strong>adolescents (under age 18) in pharmacies.From 1999 to 2002, Laboratoire HRA Pharma focused itsenergy on the international development of NorLevo viaproduct licensing agreements. As a result, NorLevo isnow available in over 50 countries.In parallel, the company has developed new products,and today Laboratoire HRA Pharma has four products:NorLevo, Lysodren, Gymiso and Cicatridine. Thecompany has a worldwide exclusive licence agreement<strong>for</strong> the KPH Hip Protector, which is commercialisedthrough licensing agreements. HRA Pharma alsocurrently promotes some products from the portfolio ofOrion Pharma (Finland) in France.In 2005, HRA Pharma completed an alliance withCelogos, an emerging biotechnology company in thefield of cell therapy.IDSSTAND 33Immunodiagnostic Systems (IDS)offers a range of esotericimmunoassay kits <strong>for</strong> clinical and research use. Thecompany focuses on bone and mineral metabolism andgrowth factor research, and engages in collaborativeprojects with researchers worldwide.IDS is a leader in the field of vitamin D analysis, offeringboth manual and automated 25-hydroxyvitamin Dmethods, an award-winning 1,25-dihydroxyvitamin DRIA system, and now announcing a 1,25-dihydroxyvitamin D EIA that employs the provenimmunocapsule sample preparation. The IDS VDBPreagent pack has recently been launched to provide ameasure of the specific capacity of vitamin D bindingprotein <strong>for</strong> vitamin D compounds in serum samples.IDS offers a full range of bone and skeletal products,covering intact PTH, bone-specific alkaline phosphatase(Ostase ® BAP), BoneTRAP ® , RatTRAP TM , MouseTRAP TM ,urinary DPD, RANKL and OPG (osteoprotegerin) <strong>for</strong> bothclinical and research (animal) use. The IDS growth andresearch product range includes IGF-I (animal andhuman use), IGFBP-1 and -3 (animal), corticosterone(animal) and POMC.In the UK, IDS also distributes products of otherreputable suppliers such as DRG, Brahms, IBL, Cayman,BBI, Diaclone etc.Visit www.idsltd.com <strong>for</strong> more in<strong>for</strong>mation.Immunodiagnostic Systems (IDS) Ltd, 10 Didcot Way,Boldon Business Park, Boldon NE35 9PD, UK (Tel: +44(0)191 5190660; Fax: +44 (0)191 5190760; Email:marketing@idsltd.com; Web: www.idsltd.com).www.ece2006.com 77EXHIBITOR AND SPONSOR PROFILES
8th European Congress of <strong>Endocrinology</strong>EXHIBITOR AND SPONSOR PROFILES78Exhibitor and Sponsor Profiles - continuedIpsen LtdSTANDS 12-15Ipsen is a European pharmaceuticalgroup with over 20 products onthe market and a total worldwide staff of nearly 4000.The company's development strategy is based on acombination of products in targeted therapeutic areas(oncology, endocrinology and neuromuscular disorders),which are growth drivers, and primary care productswhich contribute significantly to its research financing.This strategy is also supported by an active policy ofpartnerships. The locations of its four research anddevelopment centres (Paris, Boston, Barcelona andLondon) give the group a competitive edge in gainingaccess to leading university research teams and highlyqualified personnel. In 2004, research and developmentexpenditure reached €143.2 million, or 18.7% ofconsolidated sales. These amounted to €767.8 million inthe group's pro-<strong>for</strong>ma accounts set up according to theIFRS. More than 650 people in research anddevelopment are dedicated to the discovery anddevelopment of innovative drugs <strong>for</strong> patient care.Ipsen Ltd, 42 rue du Dr Blanche, France(Tel: +33 -1 -44304315; Fax: +33 -1 -44304200;Web: www.ipsen.com).LINCO ResearchSTAND 5LINCO Research develops, manufactures and markets"gold standard" RIA and ELISA immunodiagnostic test kitsused worldwide <strong>for</strong> diabetes and obesity research, andLINCOplex ® multi-analyte panels using Luminex xMAPtechnology. LINCOplex panels are available <strong>for</strong>cytokines/chemokines, as well as biomarkers <strong>for</strong> the studyof metabolic disease (diabetes, obesity, cardiac disease).LINCO Research, 6 Research Park Drive, St Charles, MO63304, USA (Tel: +1 636-441-8400; Fax: +1 636-441-8050; Email: info@lincoresearch.com; Web:www.lincoresearch.com)The Pituitary FoundationSTAND 30The Pituitary Foundation is anational UK charity which isworking to provide in<strong>for</strong>mation and support to thoseliving with pituitary disorders, including patients, theirrelatives, friends and carers. We also work to increasepublic awareness and act as a 'Patient Voice' in order toimprove services and policies to meet the needs of thepituitary population.We provide support to patients, carers and relativesincluding:• An In<strong>for</strong>mation and Support Helpline (0845 450 0375)Open 9:00 to 5:00 Mondays through Fridays• An Endocrine Nurse Helpline (0845 450 0377)Open Tuesday Mornings 9:30 to 12:30 and ThursdayEvenings 6:30 to 9:30• A Network of Local Support Groups around the UnitedKingdom and Ireland• A Telephone Buddy Support Network• An Ongoing Schedule of National and RegionalConferences• In<strong>for</strong>mational NewslettersThe Pituitary Foundation also acts as a source ofvalidated in<strong>for</strong>mation <strong>for</strong> patients, carers, primary careand other clinicians, and raises public awareness ofpituitary disorders. This includes leaflets on conditionsand publications <strong>for</strong> patients and GPs. We also providein<strong>for</strong>mation on particular conditions and lifestyle issues.Pituitary Foundation, PO Box 1944, Bristol BS99 2UB, UK(Tel: +44 (0)845 450 0376; Web: www.pituitary.org.uk).Pfizer Endocrine CareSTAND 1Thank you <strong>for</strong> inviting us to workclosely with you to best serve yourpatients' needs. We take pleasure in inviting you to visitour Pfizer Endocrine Care exhibition booth during the8th European Congress of <strong>Endocrinology</strong>:• Study the data supporting the medical rationale <strong>for</strong>treating adult growth hormone deficiency (GHD)across different age and patient groups, includingtransition and older adult GHD patients• Celebrate the 10th anniversary of the first use ofSomavert in humans• Learn how Somavert benefits the acromegaly patientwith diabetes• Find out more about KIMS and AcrostudyPfizer Endocrine Care are sponsoring two satellitesymposia during the congress which we hope you areable to attend:Young, middle-aged, and elderly patients with GHdeficiency: insights into age-related responses to GHreplacement on Monday 3 April, 12.20-13.50 in theClyde AuditoriumClinical management of acromegaly: applying 10years of human experience with pegvisomant onMonday 3 April, 18.30-20.00 in the Clyde AuditoriumWe look <strong>for</strong>ward to welcoming you to the booth, andhope you have an enlightening and productive ECE 2006!www.ece2006.com
8th European Congress of <strong>Endocrinology</strong>Exhibitor and Sponsor Profiles - continuedOrganonOrganon have kindly supportedthe Internet Café at ECE 2006.Organon are not exhibiting at ECE 2006.Organon - with shared head offices in Roseland, NJ, USAand Oss, The Netherlands - creates, manufactures andmarkets prescription medicines that improve the healthand quality of human life. Through a combination ofindependent growth and business partnerships, Organonstrives to remain or become one of the leadingpharmaceutical companies in each of its core therapeuticfields: gynecology, fertility, neuroscience and anesthesia.Organon products are sold in over 100 countries, of whichmore than 60 have an Organon subsidiary. Organon is thehuman health care business unit of Akzo Nobel.S. Karger PublishersSTAND 4Karger's range of publications inthe field of endocrinology includesthe scientific journals Hormone Research (Editor-in-Chief:P. Czernichow, Paris) and Neuroendocrinology (Editor-in-Chief: R. Millar, Edinburgh), as well as the book seriesEndocrine Development edited by M.O. Savage andFrontiers of Hormone Research edited by A.B. Grossmann.New releases presented during the 8th EuropeanCongress of <strong>Endocrinology</strong> Growth Hormone Deficiency inAdults, edited by J.O.L. Jørgensen and J.S. Christiansen,Pituitary Surgery - A Modern Approach, edited by E.R.Laws, Jr. and J.P. Sheehan, Yearbook of Pediatric<strong>Endocrinology</strong> 2005, edited by J-C. Carel and Z.Hochberg, and many more. Publications are accessibleonline at www.karger.com/endocrinology, with full-textsearch of articles and many other services.S. Karger Medical and Scientific Publishers is aninternational privately-owned publishing house, whichcombines highly sophisticated production technologywith customized services <strong>for</strong> its authors, editors andreaders.Schering HealthcareSTAND 21Schering is the UK subsidiary ofSchering AG, a research-basedpharmaceutical company based in Berlin, Germany. Wefocus on four strategic business areas: gynaecology &andrology, oncology, diagnostic imaging and specializedtherapeutics.Our andrology portfolio consists of Nebido ® (testosteroneundecanoate) and Testogel ® (testosterone) licensed <strong>for</strong>the treatment of hypogonadism in men.As a successful pharmaceutical company, we are investingin the future of medicine, developing drugs of highmedical value so as to continuously improve quality of life.Making the most of knowledge, we use interdisciplinarynetworks to build bridges to academic researchers aroundthe world, as well as to highly specialised biotechnologypioneers and partners in the pharmaceutical industry. Wecombine our own long-standing medical andpharmaceutical expertise with the latest discoveries fromgenomic research. Throughout, our research focuses on ameaningful combination of early diagnosis, prevention,treatment and therapy control.Shire PharmaceuticalsSTAND 34Shire Pharmaceuticals Group plc isa global specialty pharmaceuticalcompany with a strategic focus on meeting the needs ofthe specialist physician. Shire currently focuses ondeveloping projects and marketing products in the fieldsof the CNS, gastrointestinal tract and renal diseases. Shirehas operations in the world's key pharmaceutical markets(USA, Canada, UK, France, Italy, Spain and Germany) aswell as a specialist drug delivery unit in the USA.For further in<strong>for</strong>mation, visit www.shire.com.WisepressSTAND 36-37Wisepress OnlineBookshop ispleased to present a display of titles selected from theworld's leading publishing houses especially <strong>for</strong> <strong>ECE2006</strong>, incorporating the British Endocrine Societies. Alltitles can be bought or ordered either at the congress orvia our web site: www.wisepress.co.uk. We can also orderfree sample copies of the journals on display <strong>for</strong> you, andtake subscription orders. Whatever your bookrequirements, Wisepress will be happy to help. Whetheryou are an author seeking a publisher or are havingdifficulty obtaining a title, our professional staff will behappy to assist you.Wisepress Online Bookshop, The Old Lamp Works, 25High Path, Merton Abbey, London SW19 2JL, UK (Email:bookshop@wisepress.co.uk; Web: www.wisepress.co.uk).EXHIBITOR AND SPONSOR PROFILESwww.ece2006.com 79
8th European Congress of <strong>Endocrinology</strong>General UK In<strong>for</strong>mationGENERAL UK INFORMATION80BankingMost banks are open from Monday to Friday between0900 and 1700. Some city centre offices are also openon Saturday mornings. Automatic teller machines (ATMs)are widely available throughout the area and most arelinked to Cirrus, Maestro or Plus International moneysystems. Visitors are advised to check with their localbank prior to travelling.Bureaux de changeBureaux de change can be found at the airports, railwaystations, most city centre banks, Tourist In<strong>for</strong>mationCentres and travel outlets.Credit cardsMost hotels, restaurants and shops in the UK acceptmajor credit cards such as Visa, Mastercard, AmericanExpress, Diners Club and JCB.CurrencyUK currency is the pound sterling (£) and is made up of100 pence (p). Several Scottish banks issue their ownnotes in denominations of £5, £10, £20, £50 and £100.These are also legal tender elsewhere in the UK. Likewise,English and Northern Irish banknotes are legal tender inScotland. Coins come in denominations of 1p, 2p, 5p,10p, 20p, 50p, £1 and £2.CustomsFor in<strong>for</strong>mation regarding customs and duty freeallowances, please see the HM Revenue and Customsweb site (www.hmrc.gov.uk/home.htm).ElectricityThe standard voltage in the UK is 240V AC, 50Hz. Anynon-UK appliance will require an adapter; NorthAmerican appliances will need a trans<strong>for</strong>mer and anadapter. Plugs have three square pins and adapters arewidely available.Embassies and consulatesForeign embassies can assist travellers with lost or stolenpassports and provide assistance in emergencies. Forin<strong>for</strong>mation on European Union embassies in the UK seewww.cec.org.uk.Emergency servicesFor police, fire brigade, ambulance and, in some areas,mountain rescue or coastguard, dial 999.Health careEU citizens are entitled to free or reduced cost medicaltreatment at National Health Service hospitals. With theexception of accident and emergency treatment, all non-EU members will be charged <strong>for</strong> medical treatment andmust have adequate health insurance when travelling.SmokingSmoking in Scotland is prohibited in enclosed publicplaces from 26 March 2006.TelephoneMost public telephones accept coins (10p, 20p, 50p,£1), with a minimum connection charge of 20p. Anincreasing number of kiosks also accept credit cards andoffer email and internet access.TimeBetween late March and late October, British SummerTime applies in the whole UK. This is 1 hour ahead ofGreenwich Mean Time. Most public transport timetablesuse the 24-hour clock.TippingThere are no exact rules <strong>for</strong> tipping in the UK. If you arehappy with the service, a 10-15% tip is customary,particularly in a restaurant or café with table service.Tipping is not expected in bars. For taxi fares, it is usualto round up to the nearest pound (£).Travel insuranceIt is strongly recommended that visitors to the UKarrange travel insurance to cover the loss of possessionsand money as well as health and dental treatment.VaccinationsNo vaccinations are required prior to visiting the UK.Value-added tax (VAT)All purchases in Britain, with the exception ofunprepared food and books, are subject to VAT, whichincreases the cost of an item by 17.5%. This is generallyalready included in the requested price. Visitors fromnon-EU countries can claim a refund of VAT fromselected shops on goods that are to be taken out of thecountry, under the Retail Export Scheme.VisasEU members may travel and work in the UK without avisa. Citizens from the USA, Canada, South Africa,Australia or New Zealand do not require a visa to visitthe UK but are prohibited from working. Citizens fromother countries require a visa, which can be obtainedfrom their nearest British Consular office. For additionalin<strong>for</strong>mation on UK immigration and visa requirementsvisit the Foreign and Commonwealth Office web site(www.fco.gov.uk).www.ece2006.com
TIMETABLE8th European Congress of <strong>Endocrinology</strong>07.0007.3008.0008.3009.0009.3010.0010.3011.0011.3012.00Key to Meet the Expert Sessions1: Macroprolactinaemia2: Gestational diabetes3: Chips, arrays and biosensors: bioin<strong>for</strong>maticsin endocrine research4: Cell immortalisation in endocrine research5: Papillary thyroid cancer management6: Adrenal carcinoma7: Transgenic techniques8: Pitfalls in signal transduction research9: Medical management of Cushing's disease10: Graves' ophthalmopathy11: Metabolic, functional and oncologicalconsequences of altered GH/IGF expression12: Growth hormone deficiency in adults13: Pregnancy-related pituitary disorders14: Hypoglycaemia and insulinoma15: Interference in hormone assays16: Mouse genetics in the identification ofquantitative traitsSATURDAY 1 APRIL07.0007.3008.0008.3009.0009.3010.0010.3011.0011.3012.00Meet the Expert 1 (CA)Meet the Expert 2 (LA)Meet the Expert 1 (CA)Meet the Expert 2 (LA)SUNDAY 2 APRILMeet the Expert 3 (H1)Meet the Expert 4 (FR)Symposium 1: Thyroid and the heart (CA)Symposium 2:The endocrinology of psychiatric disease (LA)Clinical Management Workshop 1:Green over-the-counter endocrinology (H1)Oral Communications 1: Signal transduction (AR)Young Endocrinologists Session: Presentingyour research - getting your work known (FR)COFFEETransatlantic Medal LectureD MangelsdorfHALL 3CAMeet the Expert 3 (H1)Meet the Expert 4 (FR)07.0007.3008.0008.3009.0009.3010.0010.3011.0011.3012.00Meet the Expert 5 (CA)Meet the Expert 6 (LA)Symposium 5:Novel peptides in reproduction (CA)Oral Communications 3:Clinical endocrinology (H1)Symposium 6:Hot topics (LA)Symposium 7:Flies, worms and fish:use in endocrine research (FR)Clinical <strong>Endocrinology</strong> TrustVisiting Professor LectureW CrowleyMeet the Expert 5 (CA)Meet the Expert 6 (LA)MONDAY 3 APRILCOFFEEMeet the Expert 7 (H1)Meet the Expert 8 (FR)HALL 3CAMeet the Expert 7 (H1)Meet the Expert 8 (FR)07.0007.3008.0008.3009.0009.3010.0010.3011.0011.3012.00Meet the Expert 9 (CA)Meet the Expert 10 (LA)Symposium 9:Stromal cell-matrix interactions (LA)Symposium 10:Controversies in male health (CA)Oral Communications 5:Neuroendocrinology and neoplasia (FR)Nurses Session:Metabolic syndrome (AR)British Thyroid AssociationPitt-Rivers LectureB VennströmMeet the Expert 9 (CA)Meet the Expert 10 (LA)TUESDAY 4 APRILCOFFEEMeet the Expert 11 (H1)Meet the Expert 12 (FR)07.0007.3008.0008.3009.0009.3010.00COFFEEHALL 3 10.30HALL 3CAMeet the Expert 11 (H1)Meet the Expert 12 (FR)11.0011.3012.00WEDNESDAY 5 APRILMeet the Expert 13 (CA) Meet the Expert 15 (H1)Meet the Expert 14 (LA)Symposium 13: Monogenic disordersilluminate metabolic disease (CA)Symposium 14:Steroid hormone receptors (H1)Symposium 15:Anabolic hormones in sport (LA)Oral Communications 7:Calcium and bone (FR)Clinical <strong>Endocrinology</strong>Trust LectureA WeetmanPlenary 3:Stem cells: regeneration in type 1 diabetes (LA)Debate (CA)Meet the Expert 16 (FR)CA12.3013.0013.3014.0014.3015.0015.3016.0016.3017.0017.3018.00Registration(from 12.00 onwards)Opening CeremonyEuropean Journal of <strong>Endocrinology</strong>Prize LectureS CostagliolaGeoffrey Harris Prize LectureF CasanuevaHALL 3CACACA12.3013.0013.3014.0014.3015.0015.3016.0016.3017.0017.3018.00Novartis PharmaceuticalsSatellite Symposium:From controversy to clarity inacromegaly managementPOSTERS& LUNCHHALL 3Symposium 3:Cancer and the skeleton (CA)Symposium 4:Cannabinoid signalling (LA)Clinical Management Workshop 2:Management of complex genital anomalies andthe transition from childhood to adulthood (FR)Oral Communications 2:Steroids and reproductive endocrinology (H1)TEAPlenary 1:Vitamin D actionFRHALL 3CA12.3013.0013.3014.0014.3015.0015.3016.0016.3017.0017.3018.00Shire PharmaceuticalsSatellite Symposium:PCOS - The cruel faceof a complex diseaseBM1BM2FRPfizer SatelliteSymposium 1:Young, middle-agedand elderly patientswith GHD: insights intoage-related responses toGH replacement CAPOSTERS& LUNCHSymposium 8:Clinical lessons from novel aspects ofG protein-coupled receptors signalling (CA)Clinical Management Workshop 3:Management of Graves' ophthalmopathy (LA)Basic Workshop:In vivo imaging of signalling (H1)Oral Communications 4:Diabetes and metabolism (FR)TEAPlenary 2:Statins and rhabdomyolysis12.3013.0013.3014.0014.3015.0015.3016.0016.3017.00European <strong>Society</strong> of <strong>Endocrinology</strong> AGMPOSTERS& LUNCHHALL 3 HALL 3Symposium 11:How hormones get into cells (CA)Symposium 12:<strong>Endocrinology</strong> in the fetus (H1)Clinical Management Workshop 4:Contrasting practices in Europeanendocrinology (LA)Oral Communications 6:Endocrine genetics (FR)TEAHALL 3 HALL 317.30Dale Medal Lecture18.00J FindlayCACACA12.3013.0013.3014.0014.3015.0015.3016.0016.3017.0017.3018.00Meet the Expert 13 (CA) Meet the Expert 15 (H1)Meet the Expert 14 (LA)LUNCHHALL 3Symposium 16:Disorders of melanocortin receptor functions (LA)Symposium 17:Endocrine oncogenesis and management ofhereditary endocrine tumours (CA)Clinical Management Workshop 5:Research management workshop (H1)Oral Communications 8:Thyroid (FR)Novartis Oncology Young InvestigatorAward and BTA Award AnnouncementsMeeting CloseCAKey to locationsCA Clyde AuditoriumLA Lomond AuditoriumH1 Hall 1FR Forth RoomMeet the Expert 16 (FR)18.3018.3018.3018.3018.30ARAlsh Room19.0019.3020.00Welcome ReceptionGLASGOW SCIENCE CENTRE19.0019.3020.00Ipsen SatelliteSymposium:Tailoring therapies<strong>for</strong> patients withendocrine disordersCAThe Sunday SocialTIGER TIGER19.0019.3020.00Pfizer Satellite Symposium 2:Clinical management of acromegaly:applying 10 years of human experiencewith pegvisomantFree EveningCA19.0019.3020.00Congress Banquet and CeilidhHILTON HOTEL19.0019.3020.00Key to Business MeetingsBM1 <strong>Society</strong> <strong>for</strong> <strong>Endocrinology</strong> EGMCLYDE AUDITORIUMBM2British Thyroid Association AGMALSH ROOMwww.ece2006.com
SPONSORSThe ECE 2006 Organising Committee would like to thank all the sponsorsand supporters of this meeting, in particular:THE GOLD SPONSORSTHE BRONZE SPONSORSECE 2006 Secretariat<strong>Society</strong> <strong>for</strong> <strong>Endocrinology</strong>22 Apex Court, WoodlandsBradley Stoke, Bristol BS32 4JT, UKContact: Liz BrookesTel: +44 (0)1454 642210Fax: +44 (0)1454 642222Email:conferences@endocrinology.orgWebsite: www.ece2006.comThe <strong>Society</strong> <strong>for</strong> <strong>Endocrinology</strong>Company Limited by GuaranteeRegistered in England No 349408Registered office as shown aboveRegistered Charity No 26618
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