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The regulation of lin-14 mRNA translation bylin-4 RNAsThe lin-4 gene produces smallRNA that has complementarysequence of lin-14. The binding of lin-4 transcripts tothe lin-14 mRNA 3’-UTR causesdegradation of the lin-14 mRNA.microRNA (miRNA)
Current model for the formation and use ofmicroRNAs (Part 1)1. Initial RNA transcriptform hairpin loop.2. RNase (Drosha andDicer), which used inRNAi, process thestem-loop structuresto ss miRNA.
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Page 49: Next Class on Sep-15 Chapter 7, Fer

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