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Contribution of mRNA ends to translation1. Eukaryotic initiation factor-4E (eIF4E), eIF4A andeIF4G bind to 5’-cap.2. PolyA binding protein binds to polyA tail and eIF4G.3. Ribosome recognized mRNA.4. Active Translation
Translational regulation in oocytesMaskin links the 5’ and 3’ endsinto a circle by binding to CPEB(cytoplasmic polyadenylationelement-bindingprotein) andeIF4E.No TranslationSome Oocyte makes some mRNA without the methylated 5’-capto regulate the translation
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Page 49: Next Class on Sep-15 Chapter 7, Fer

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