UV-VIS-NIR

UV-VIS-NIRVarianCary 4000, 5000and 6000iSpectrophotometers

Varian Cary—At the leading edgeVarian’s Cary® range of UV-Vis-NIRspectrophotometers has been synonymouswith excellence and high performancefor over 50 years.The Cary range has become the standardfor researchers wanting to extendthe boundaries of spectrophotometricmeasurement techniques.The range is equally at home in routinelaboratories where reliability and easeof-useare vital. In fact, no matter whatyour measurement challenge, Varian’s Caryproduct range has a solution for you.The new generation Cary seriesNow, Varian introduces the latestbreakthrough in UV-Vis-NIR: the newgeneration Cary series. Comprising theCary 4000, 5000 and 6000i instruments,this research grade series sets newstandards for UV-Vis-NIR performance.With unsurpassed photometric accuracyand a wide range of flexible accessories,the new Cary series satisfies all yourmeasurement needs and is the only choicefor researchers who need to stay at theforefront of their field.Cary 4000Offering the ultimate in UV-Vis photometricperformance from 175-900 nm, the Cary4000 sets the industry standard for researchand reference spectrophotometers.Cary 5000With innovative PbSmart technology,the Cary 5000 extends the unparalleledCary performance into the NIR to 3300 nm.Cary 6000iHaving provided the world’s first UV-Vis NIRspectrophotometer with InGaAs detection,the Cary 6000i represents the secondgeneration of this technology. No otherinstrument can match the NIR performanceof the Cary 6000i.The wavelengthranges of the VarianCary 4000, 5000 and6000i instruments.2

What’s inside?The new generation Cary series featuresthe Optical Isolation System, which providesall the optical stability of an independentlymounted, research grade optical bench.Vibrational noise is reduced, as the opticscasting is mounted on an isolated systemwhich floats independently of thespectrophotometer cover and samplecompartment. The system has also beeninsulated from vibrational effects,so you can be sure that your laboratoryenvironment won’t affect yourinstrument’s performance.The Cary 4000/5000/6000i instruments alsofeature the unique LockDown mechanismthat ensures you can mount accessoriesin the sample compartment quickly, easilyand reproducibly. With the Cary LockDownmechanism, you’ll spend less time onsetup and more time on analysis.With ‘Plug-and-Go’lamp management,lamps are noweasily replaced andpre-aligned, requiringno adjustment.The lamp managementelectronics ensuresthat a wider rangeof lamp designs canbe accommodated.Schwarzchild couplingoptics ensure themaximum level of lightthroughput. This producesmore accuratemeasurements at lowtransmission levels.The slits can be fixedin the NIR as well asthe UV-Vis.A large samplecompartment, with aremovable floor plate,gives you maximumflexibility whenmounting samples.4The unique precisionLockDown mechanismallows you to positionyour accessories quicklyand reproducibly inthe sample compartment.

Unparalleled performanceThe new generation Cary range beginswith the Cary 4000. This instrument setsthe standard for photometric noise,range and linearity, providing excellentresolution across the UV-Visible spectrumfrom 175-900 nm. Featuring Varian’s newOptical Isolation System, the Cary 4000provides advances in noise and straylight reduction, making it ideal for themost challenging research applicationsor as your own primary referenceUV-Vis spectrophotometer.The Cary 5000 combines unparalleledCary performance with Varian’s innovativePbSmart technology, extending thewavelength range into the NIR to 3300 nm.PbSmart optimizes the performanceof the PbS NIR detector in real time,providing noise and linearity performancenever before achieved using thisdetector technology.The Cary 5000 can be used to achievesignificant performance breakthroughsacross a range of applications—fromquantifying out-of-band blockingcharacteristics of band pass filters ormeasuring the high transmission of nextgeneration fibre optic materials to QCapplications for testing of raw materialsor finished pharmaceutical products.6

Specialized spectrophotometersfor specialized applicationsAdvanced NIR performance foradvanced photonicsWith an operating range from 175-1800 nm,the Cary 6000i is the instrument of choicefor users needing to keep abreast of rapidlydeveloping photonics and communicationstechnologies—both now and in the future.Varian pioneered the world’s first doublebeam UV-Vis-NIR spectrophotometer withInGaAs detection to take advantage of thedramatically reduced noise and improvedsensitivity the detector provides in the NIR.The Cary 6000i represents the secondgeneration of this technology and is theworld’s most advanced UV-Vis-NIRspectrophotometer with InGaAs detection.The InGaAs detector provides superiorsignal-to-noise performance compared toconventional lead sulfide detectors.This results in improved detection limitsand increased scan rates, giving you cleanerspectra with better resolution in less time.The unmatched NIR capabilities of theCary 6000i are further enhanced by theCary Optical Isolation system and Peltierdetector cooling. Like the Cary 4000 in theUV-Vis region, the 6000i can be used asa primary reference spectrophotometerin the NIR, providing absolute accuracymeasurements without the need forreference to expensive external calibrationstandards.The addition of threefilters shows thesuperior photometricrange and linearityof the Varian Caryinstruments in the NIR.The actual andpredicted measurementsshow excellentcorrelation across theentire NIR wavelengthrange measured.Using the Cary 6000i,a high resolution NIRscan of water vaporclearly resolvesabsorption bandsaround 940 nm whichare barely visible onstandardspectrophotometers.The fine resolutiondelivered by the Cary6000i is made possiblethrough the use of adedicated 600 lines/mmNIR diffraction gratingin combination withInGaAs NIR detection.10

Varian’s technology advances don’t stop atthe spectrophotometer. The superior InGaAsand PbSmart NIR detection systems alsopower Varian’s comprehensive range ofintegrating sphere accessories. Available intwo diameters (150 mm or 110 mm) andthree model types, you can swap from PbSto InGaAs to solve the most challengingdiffuse reflectance measurements.Varian, Inc. DRAs offer a unique range offeatures , so there’s always a model to suityour needs. (Model number indicates thewavelength limit in nanometers.):• Internal/External DRA-900 –Offering exceptionally low photometricnoise, a wide photometric range andgood linearity.• Internal/External DRA-1800 –The world’s only PMT/InGaAs DRA, providingsuperior signal to noise performance forimproved detection limits and increasedscan rates. Get cleaner spectra with betterresolution more quickly.• Internal/External DRA-2500 –Extending the Cary 5000’s PbSmart NIRdetector management, the DRA PbS NIRdetector is peltier cooled and optimized inreal time, offering exceptional performance.The External DRA(150 mm integratingsphere) is idealfor reflectance ortransmissionmeasurements oflarge and physicallychallenging samples.Multiple samplemounting optionsare available.11

Simply smarter softwareNew Cary WinUV software ensures thatVarian’s widely acclaimed UV-Vis-NIRsoftware is now even more powerful andeasier to use. The modular design of theCary WinUV software means that it can betailored to suit your analyticalrequirements—whether it’s a materialsscience application using basicconcentration measurements or life scienceapplications requiring advanced enzymekinetics or thermal control.But it doesn’t stop there. Cary WinUV iscompletely customizable using the powerfulbuilt-in Applications Development Language(ADL). ADL gives you the capability tomodify the WinUV software to meet yourmost specific applications ensuring thatno matter what analytical challenges thefuture holds, you will have the capability tomeet them.With standard software packagesdesigned to meet most application needsand the power and flexibility of ADL,the Cary WinUV software is sure to meetall your requirements.21 CFR Part 11compatibilityOptional 21 CFR Part 11and GLP (GoodLaboratory Practice)compatibility is ideal forusers in thepharmaceutical industryor anyone requiringregulatory compliance.In addition, the uniqueValidate applicationenables immediatecertification of yourinstrument againstfactory, BP/EP, USP(British/European,U.S. Pharmacopoeia)specifications.12

Choose youroperating systemCary WinUV software iscompatible with bothMicrosoft® Windows® XPand Windows 2000.Enhancedgraphics featuresThe graphics controlmodule has automaticpeak labeling, zoom,free and tracking cursor,multiple ordinate andabscissa formats,smart copy/paste andoverlay modes, makingspectral interpretationand presentation forpublications a breeze.Enhanced file transferand report exportcapabilities giveCary WinUV greaterconnectivity thanany other UV-Vis-NIRsoftware. The AutoConvert functionallows you to convertyour data filesautomatically for usein another program.You can also elect tostore your data files informats that can bedirectly imported intoa spreadsheet.The optional ColorCalculation software iscompatible with theinternational colorcommission (CIE) andASTM standards, and isideal for users in thepharmaceutical, textile,automotive, paint orgraphic arts industries.Advancedspectrum calculatorUse the spectrumcalculator to applymathematical operations,including addition,subtraction, division,multiplication, log andsquare root functions,to spectra. The calculatoralso features mean,normalization, smoothing,up to fourth orderderivatives, integrationand the Kubelka-Munkcorrection algorithm.Cary WinUV’s extensiveonline help includesstep-by-step videosof hardware setup androutine maintenanceprocedures ensuringyou can get up andrunning quickly.13

Precision engineered for greater flexibility and versatilityThe Cary series has been designed forflexibility and versatility. Whether yourapplication is optics, powders, fabrics, gases,liquids, films or coatings, there is a Caryaccessory to meet your needs. Our fibreoptic technologies take measurementsbeyond the sample compartment,ensuring you can perform a full range ofmeasurements from advanced specular anddiffuse reflectance measurements to simplesolution transmittance and absorbance.If you have the application, we have thesolution. You can count on Varian’s Caryspectrophotometers to meet all your needstoday and tomorrow.Lock it down and walk awayThrow down your tools! The new generationCary series features the unique precisionLockDown mechanism that allows you toposition your accessories in yourspectrophotometer quickly and reproducibly.With just a flick of the wrist, the CaryLockDown system permits quick mounting,release and changeover of accessories soyou can spend more time on analysis andless time setting up. The Cary LockDownsystem means you can confidentlymount any accessory in the instrument,in exactly the same place time-after-time –eliminating tools and time-consumingalignment procedures.Plug-and-GoThe Cary’s Plug-and-Go lamp managementfeature makes lamp replacement easy,as lamps are pre-aligned and don’t requireany adjustments. And, it’s more flexiblewith the ability to accommodate a widerrange of lamp designs to match yourapplication needs. A mercury lamp modulefor wavelength accuracy validation issupplied with all high-end Caryspectrophotometers, allowing you to verifywavelength accuracy in one simple step.SafetyAlthough Varian’s products are designedto be safe and to comply with all applicableregulatory requirements, it is important tobe familiar with the hazards associatedwith these products. For full details, refer towww.varianinc.comThe Cary Series is certifiedto comply with therequirements of the EMC andLV directives of the European Union.141 Insert accessory intothe sample compartment2 Position accessoryover mounting holes3 Flick the switch tolock the accessory down

A family of solutionsVarian’s vast arrayof hardware solutionsensures you can handlethe widest varietyof sample sizes–fromthe smallest etalon touncut sheet glass,from micro-flowcellsto long path gas cells.The huge Carysample compartmentaccommodatesmost sample sizes,while the removablesample compartmentfloor means even moreflexibility is provided.The new generation Cary series are partof Varian’s range of Cary molecularspectrophotometers, which also includesthe Cary 50, 100 and 300 UV-Visspectrophotometers and the Cary Eclipsefluorescence spectrometer.With xenon flash lamp technology,plug-and-identify electronics and featurepacked,intuitive software, the Cary Eclipseinstrument embodies the Cary name.When combined with the optional solidsample holder, the Cary Eclipse can be usedfor a variety of materials scienceapplications—from measuring opticalcomponents for unwanted fluorescenceto measuring specialty chemicals such asoptical brighteners.For the measurement of large samplessuch as optical filters, the Cary Eclipse canbe used in conjunction with Varian’s fibreoptic system (as shown above). The CaryEclipse fibre optic system takes the light tothe sample, enabling the fluorescencespectra of large, heavy and oddly shapedobjects such as rocks, gems and otherminerals to be measured.For further information on Varian’s rangeof Cary 50, 100, 300 UV-Vis or Cary Eclipsefluorescence spectrophotometers, ask yourVarian sales representative for a brochure,or visit our website at www.varianinc.com.To keep your Caryinstruments runningsmoothly, Varian alsooffers a wide rangeof the highest qualityconsumable supplies,including cuvettes,reference materialsand lamps.15

Varian, Inc.serving worldwide markets in:AgricultureBasic ChemicalBiotechnologyClinicalElectronicsEnvironmentalPhotonicsToxicologyPharmaceuticalFood and BeverageMetals and MiningPetroleum and PetrochemicalVarian, Inc. is committedto a process of continuousimprovement whichdemands that weunderstand and then meetor exceed the needs andexpectations of ourcustomers—both insideand outside the company—in everything we do.• Varian Sales and Dealer OfficesQUALITY SYSTEMC E R T I F I E DAll trademarks are the propertyof their respective owners.Specifications subject to changewithout notice.Varian, Inc. • www.varianinc.com• North America 800.926.3000, 1.925.939.2400• Europe The Netherlands 31.11.867.1000• Asia Pacific Australia 613.9560.7133• Latin America Brazil 55.11.3845.0444• China 86.21.6375.6969• Japan 81.3.5232.1239• Korea 82.2.3452.2452• Taiwan 886.22.698.9555• India 91.22.2431.3069Other sales offices and dealers throughout the worldGC • LC • MS • AAS • ICP • UV-Vis-NIR • FT-IR • Raman • Fluorescence • Dissolution • NMR • Consumable Products8510194200 8/04 Printed in AustraliaPrinted on environmentally friendly paper. Design: Digital Image. Photography: Parallax