2009 CAUTI guidelines - Centers for Disease Control and Prevention

Development of Key QuestionsWe first conducted an electronic search of the National Guideline Clearinghouse® (Agency forHealthcare Research and Quality), Medline® (National Library of Medicine) using the Ovid®Platform (Ovid Technologies, Wolters Kluwer, New York, NY), the Cochrane® HealthTechnology Assessment Database (Cochrane Collaboration, Oxford, UK), the NIH ConsensusDevelopment Program, and the United States Preventive Services Task Force database forexisting national and international guidelines relevant to CAUTI. The strategy used for theguideline search and the search results can be found in Appendix 1A. A preliminary list of keyquestions was developed from a review of the relevant guidelines identified in the search. 1,35,36Key questions were finalized after vetting them with a panel of content experts and HICPACmembers.Literature SearchFollowing the development of the key questions, search terms were developed for identifyingliterature relevant to the key questions. For the purposes of quality assurance, we comparedthese terms to those used in relevant seminal studies and guidelines. These search terms werethen incorporated into search strategies for the relevant electronic databases. Searches wereperformed in Medline® (National Library of Medicine) using the Ovid® Platform (OvidTechnologies, Wolters Kluwer, New York, NY), EMBASE® (Elsevier BV, Amsterdam,Netherlands), CINAHL® (Ebsco Publishing, Ipswich, MA) and Cochrane® (CochraneCollaboration, Oxford, UK) (all databases were searched in July 2007), and the resultingreferences were imported into a reference manager, where duplicates were resolved. ForCochrane reviews ultimately included in our guideline, we checked for updates in July 2008.The detailed search strategy used for identifying primary literature and the results of the searchcan be found in Appendix 1B.Study SelectionTitles and abstracts from references were screened by a single author (C.V.G, R.K.A., orD.A.P.) and the full text articles were retrieved if they were 1) relevant to one or more keyquestions, 2) primary analytic research, systematic reviews or meta-analyses, and 3) written inEnglish. Likewise, the full-text articles were screened by a single author (C.V.G. or D.A.P.) usingthe same criteria, and included studies underwent a second review for inclusion by anotherauthor (R.K.A.). Disagreements were resolved by the remaining authors. The results of thisprocess are depicted in Figure 2.27