DQ8-villin-IL-15tg

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IL-15 IN THE LAMINA PROPRIA? ?Role of DQ8Role of TG2?IL-15 IN THE EPITHELIUMAdaptive immune response(anti-TG2 antibodies)Innate epithelial response(IL-15, epithelial stress markers)IEL activation↓Inhibitory NKG2A↑Activatory NKR (CD94+NKG2A-, NKG2D+)VILLOUS ATROPHY
AcknowledgmentsValerie AbadieWilliam R. DePaoloFangming TangCezary CiszewskiHannah Fehlner-PeachWenxia WangMala SettySarah KamasawkiBen SallyValentina DiscepoloStefano GuandaliniSonia KupferCarol SemradJ. TurnerMayo clinic, RochesterEric MariettaJoe MurrayUniversity Frederico II, NaplesR. TronconeS . AuricchioV.M. SalvatiValentina DiscepoloColumbia Presbyterian HospitalP.HR GreenG. BhagatNIH, BethesdaY. BelkaidJ. HallT.A. Waldmann
Page 1 and 2: SYNERGISTIC ROLE OF IL-15IN THE EPI
Page 3 and 4: Intestinal HomeostasisDefault respo
Page 5 and 6: Is there a link between dysregulate
Page 7 and 8: IL-15 induces an inflammatory IFN-
Page 9 and 10: Perspectives: Blocking IL-15 signal
Page 11 and 12: DQ8-D d -IL-15tg mice fed gluten ph
Page 13 and 14: Effector intraepithelial CTL killst
Page 15 and 16: INNATE IMMUNE ACTIVATION“CD4 anti
Page 17 and 18: SHAMDQ8 DQ8-D d -IL-15tg DQ8-villin
Page 19 and 20: DQ8-D d -villin-IL-15tg mice fed gl
Page 21: In absence of DQ8D d -villin-IL-15t

DQ8-villin-IL-15tg

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