DQ8-villin-IL-15tg
DQ8-villin-IL-15tg DQ8-villin-IL-15tg
The celiac icebergVillous atrophy+/- clinical manifestations?Potential CDAnti-TTG and normal histology
Effector intraepithelial CTL killstressed epithelial cellsCTLCTLgliadinαβ TCRαβ TCRInduction of activatingnatural killer receptorsInduction of ligands foractivating natural killerIECgliadinIECstressDirect recognitionof gliadin peptidesIndirect gluten“stress-mediated” response
- Page 1 and 2: SYNERGISTIC ROLE OF IL-15IN THE EPI
- Page 3 and 4: Intestinal HomeostasisDefault respo
- Page 5 and 6: Is there a link between dysregulate
- Page 7 and 8: IL-15 induces an inflammatory IFN-
- Page 9 and 10: Perspectives: Blocking IL-15 signal
- Page 11: DQ8-D d -IL-15tg mice fed gluten ph
- Page 15 and 16: INNATE IMMUNE ACTIVATION“CD4 anti
- Page 17 and 18: SHAMDQ8 DQ8-D d -IL-15tg DQ8-villin
- Page 19 and 20: DQ8-D d -villin-IL-15tg mice fed gl
- Page 21 and 22: In absence of DQ8D d -villin-IL-15t
- Page 23 and 24: AcknowledgmentsValerie AbadieWillia
Effector intraepithelial CTL killstressed epithelial cellsCTLCTLgliadinαβ TCRαβ TCRInduction of activatingnatural killer receptorsInduction of ligands foractivating natural killerIECgliadinIECstressDirect recognitionof gliadin peptidesIndirect gluten“stress-mediated” response
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