DQ8-villin-IL-15tg

More documents

Recommendations

Info

Intraepithelial lymphocytosis, anti-gliadin and anti-transglutaminaseIgG and IgA in in gliadin fed DQ8-D d -IL-15tg miceDQ8DQ8-D d -IL-15tg
DQ8-D d -IL-15tg mice fed gluten phenocopythe early stages of Celiac Disease characterized by the inductionof an adaptive anti-gluten immunity in the absence of villous atrophy(Potential Celiac Disease)• IFN-γ + and IL-21 + anti-gluten CD4 + T cell responses• Anti-gliadin antibodies•Autoantibodies: Anti-transglutaminases•Infiltration of intraepithelial lymphocytesMarsh 1Marsh 1DePaolo R.W. & Abadie V.et al., Nature, 2011
Page 1 and 2: SYNERGISTIC ROLE OF IL-15IN THE EPI
Page 3 and 4: Intestinal HomeostasisDefault respo
Page 5 and 6: Is there a link between dysregulate
Page 7 and 8: IL-15 induces an inflammatory IFN-
Page 9: Perspectives: Blocking IL-15 signal
Page 13 and 14: Effector intraepithelial CTL killst
Page 15 and 16: INNATE IMMUNE ACTIVATION“CD4 anti
Page 17 and 18: SHAMDQ8 DQ8-D d -IL-15tg DQ8-villin
Page 19 and 20: DQ8-D d -villin-IL-15tg mice fed gl
Page 21 and 22: In absence of DQ8D d -villin-IL-15t
Page 23 and 24: AcknowledgmentsValerie AbadieWillia

DQ8-villin-IL-15tg

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?