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ESI and today also MALDI solved an old analytical problem routine, sensitive and robust coupling of HPLC to MS
ESI and today also MALDI solved an old analytical problem routine, sensitive and robust coupling of HPLC to MS accompanied by a dramatic advancement of MS instruments which also strongly improves small-molecule analyses
Page 1 and 2: From Small-Molecule Drugs to Proteo
Page 5 and 6: Relative AbundanceTandemMSorMS/MSM
Page 8 and 9: 5000400030002000conferenceuntil 200
Page 10 and 11: MALDI- Matrix AssistedLaser Desorpt
Page 12: nevertheless a difficult start
Page 16: can an exact protein molecular mass
Page 20 and 21: % Intensity% IntensityNative MALDI
Page 24 and 25: Small-molecule MALDIQuantification
Page 26: Analyte/IS*ConcAnalyte/IS*Conc10.90
Page 32 and 33: in order to analyze a proteome key
Page 34: 1-the conventional way :"MALDI pept
Page 37: Protein Identifizierung : ESI or MA
Page 40 and 41: in order to analyze a proteome key
Page 44 and 45: Remaining problems :• possibly lo
Page 46 and 47: (self)critical discussion about pro
Page 48 and 49: ut with large efforts and investmen
Page 51: the alternative.....back to hypothe
Page 55 and 56: A new tool MALDI imaging mass spect
Page 57: AK KarasU. Bahr, Ph.DB. Meyer, Ph.D

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