chitosan and plga microspheres as drug delivery ... - UniCA Eprints

4.2.8. Viability Studies with A549 Cells 684.3. Conclusion 695. RIFAMPICIN LOADED CHITOSAN MICROSPHERES PREPARED BY SPRAY-DRYING METHOD 715.1. Materials and Methods 725.1.1. Material 725.1.2. Preparation of RFP-Loaded Chitosan Microspheres 725.1.3. Characterization of RFP-Loaded Chitosan Microspheres 735.1.4. Release Studies/Stability Studies 745.1.5. Mucoadhesive Studies 755.1.6. Statistical Analyses 755.2. Result And Discussion 755.2.1. Preparation of RFP-Loaded Chitosan Microspheres 755.2.2. Size and Morphological Characteristics of Microspheres 765.2.3. Surface Charge 785.2.4. Entrapment Efficiency (E%) 785.2.5. Nebulization Studies of Chitosan Microspheres 795.2.6. Release/Stability Studies 815.2.7. Mucoadhesive Studies 825.3. Conclusions 836. RIFAMPICIN LOADED PLGA MICROSPHERES PREPARED BY SOLVENTEVAPORATION METHOD 856.1. Materials and Methods 866.1.1. Material 866.1.2. Preparation of PLGA Microspheres 866.1.3. Characterization of RFP-Loaded PLGA Microspheres 876.1.4. Release Studies/Stability Studies 886.1.5. Mucoadhesive Studies 896.1.6. Cell Culture 896.1.7. Statistical Analyses 906.2. Result and Discussion 906.2.1. Preparation of RFP-Loaded PLGA Microspheres 906.2.2. Size and Morphological Properties of PLGA Microspheres 916.2.3. Surface Charge 926.2.4. Entrapment Efficiency (E%) 926.2.5. Nebulization Studies of PLGA Microspheres 946.2.6. Release/Stability Studies 966.2.7. Mucoadhesive Studies 976.2.8. Viability Studies with A549 Cells 986.3. Conclusions 997. RIFAMPICIN LOADED PLGA COATED CHITOSAN MICROSPHERESPREPARED BY WSD METHOD 1017.1. Materials and Methods 1037.1.1. Material 1037.1.2. Preparation of RFP-Loaded PLGA Coated Chitosan Microspheres 1037.1.3. Characterization of RFP-Loaded PLGA Coated Chitosan Microspheres 1046