â Realizing the potential of IonWorks screening in a drug discovery ...
â Realizing the potential of IonWorks screening in a drug discovery ...
â Realizing the potential of IonWorks screening in a drug discovery ...
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Pre- to post-addition current amplitudechanges12005.12.06 Na vChip 1 -55mV to 005.12.06 Na vChip 2 -100mV to 011.27.07 Na vChip 1 -55mV to -10mV11.27.07 Na vChip 2 -100mV to -10mV7010060Cell Number8060402000-56-1011-1516-2021-2526-3031-35Pre - Post Current Change (%)36-4041-4546-5051-5556-6061-6566-7071-7576-8081-8586-9091-9596-100Cell Number504030201000-56-1011-1516-2021-2526-3031-35Pre - Post Current Change (%)36-4041-4546-5051-5556-6061-6566-7071-7576-8081-8586-9091-9596-100The histograms here depict <strong>the</strong> trend <strong>in</strong> current amplitude change (absolute change) that is seenwhen compar<strong>in</strong>g current record<strong>in</strong>gs prior to and follow<strong>in</strong>g a s<strong>in</strong>gle buffer addition. Record<strong>in</strong>gs wereobta<strong>in</strong>ed from hold<strong>in</strong>g <strong>potential</strong>s <strong>of</strong> ei<strong>the</strong>r -55mV or -100mV.