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2010 BC Guide in Determining Fitness to Drive

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Less commonly, dementias can result from: head <strong>in</strong>jury and trauma bra<strong>in</strong> tumours depression hydrocephalus (excessive accumulation of cerebrosp<strong>in</strong>al fluid (CFS) <strong>in</strong> the bra<strong>in</strong>) bacterial and viral <strong>in</strong>fections <strong>to</strong>xic, endocr<strong>in</strong>e, and metabolic causes, or anoxia.Some of these dementias may be reversible. Specific examples of reversible causes of dementia<strong>in</strong>clude: thyroid deficiency or excess vitam<strong>in</strong> B12 deficiency chronic alcoholism abnormal calcium levels dementia associated with celiac disease, and <strong>in</strong>tracranial space-occupy<strong>in</strong>g lesions.Treatment for dementia has become available over the last decade with cognition enhanc<strong>in</strong>gdrugs such as donepezil (Aricept ), galantam<strong>in</strong>e (Rem<strong>in</strong>yl) and rivastigm<strong>in</strong>e(Exelon). These drugs seem <strong>to</strong> improve symp<strong>to</strong>ms of the disease <strong>in</strong> some stages of dementiabut their therapeutic effect is variable. It is generally considered not likely that treatment withmedication would improve cognition <strong>to</strong> a degree that would enable driv<strong>in</strong>g <strong>in</strong> those whosedriv<strong>in</strong>g skills had decl<strong>in</strong>ed <strong>to</strong> an unsafe level or those who had previously failed a driv<strong>in</strong>gassessment due <strong>to</strong> cognitive impairment.Mild cognitive impairmentMild cognitive impairment (MCI) is a term that usually refers <strong>to</strong> the transitional state betweenthe cognitive changes associated with normal ag<strong>in</strong>g and the fully developed cl<strong>in</strong>ical features ofdementia. The diagnostic criteria for MCI are evolv<strong>in</strong>g but <strong>in</strong> general it describes a cognitivedecl<strong>in</strong>e that presents no significant functional impairment.DeliriumDelirium is a condition characterized by a disturbance of consciousness and a change <strong>in</strong>cognition that occurs over a relatively short period of time, usually hours <strong>to</strong> days. Commoncauses of delirium <strong>in</strong>clude: vascular disorders (e.g. stroke, myocardial <strong>in</strong>farct) <strong>in</strong>fections (e.g. ur<strong>in</strong>ary tract, chest) drugs (e.g. analgesics, sedatives, alcohol, illicit drugs), and metabolic disorders (e.g. renal failure, hepatic failure, endocr<strong>in</strong>e disorders).Although the symp<strong>to</strong>ms of delirium may be similar <strong>to</strong> dementia, delirium is temporary andtherefore considered a transient impairment for licens<strong>in</strong>g purposes.336

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