The Production of Therapeutic Proteins in Plants: Apo AI and Insulin
The Production of Therapeutic Proteins in Plants: Apo AI and Insulin The Production of Therapeutic Proteins in Plants: Apo AI and Insulin
Chemical Characterization of Purified Apo AI MilanoMS & N-terminal SequencingApo AI StandardMassExpected 28078.6 DaObserved 28076.0 DaN-terminal SequenceExpected DEPPQObserved DEPPQMassSafflower Apo AI MilanoMassExpected 27781.3 DaObserved 27780.0 DaN-terminal SequenceExpected PPQSPObserved PPQSPMass
Functional Characterization of Purified Apo AI MilanoDMPC Clearance Assay1.2001.0000.800Abs @ 325 nm0.6000.4000.2000.0000 1 2 3 4 5 6 7 8 9 10 11 12 14 16 18 20 22 24 26 28 30Time (min)DMPC (non red) ApoAI (non red) SBS Milano (non red)
- Page 1 and 2: The Production of Therapeutic Prote
- Page 3 and 4: SemBioSys OverviewLocation: Calgary
- Page 5 and 6: SemBioSys’ TechnologyProof-of-Con
- Page 7 and 8: Field Grown GMO SafflowerPlanting s
- Page 9 and 10: Purification of OilbodiesThe Proces
- Page 11 and 12: Plant Impurity AssaysPhytate (IP 6
- Page 13 and 14: Product Impurity Assays - Fusion Pa
- Page 15 and 16: Viral Load/Viral ClearanceRegulator
- Page 17 and 18: InsulinPositioned to Meet the Growi
- Page 19 and 20: Economics of Plant-Produced Insulin
- Page 21 and 22: Insulin - Equivalence DataV8 Protea
- Page 23 and 24: Insulin - Equivalence DataIGF-1 Rec
- Page 25 and 26: Insulin Characterization: Clinical
- Page 27: Apo AI Milano (SBS-2000)• FTO - S
- Page 31 and 32: Cholesterol Mobilization in vivoSBS
- Page 33: Non-Pharma ProductsProducts and Com
Functional Characterization <strong>of</strong> Purified <strong>Apo</strong> <strong>AI</strong> MilanoDMPC Clearance Assay1.2001.0000.800Abs @ 325 nm0.6000.4000.2000.0000 1 2 3 4 5 6 7 8 9 10 11 12 14 16 18 20 22 24 26 28 30Time (m<strong>in</strong>)DMPC (non red) <strong>Apo</strong><strong>AI</strong> (non red) SBS Milano (non red)