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2010 Hong Kong Reference Framework for Hypertension Care for ...

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Module 7Drug Treatment <strong>for</strong> People with <strong>Hypertension</strong>Appendix 1Class of DrugCompelling and Possible Indications and Contraindications <strong>for</strong> theMajor Classes of Antihypertensive Drugs 23CompellingIndicationsPossibleIndicationsCompellingContraindicationsPossibleContraindicationsACE Inhibitors(ACEI)Heart failure,Left ventriculardysfunction,Post myocardialinfarction,DiabeticnephropathyProteinuric renaldiseasePregnancy,Bilateral renalartery stenosis,HyperkalaemiaRenal impairmentAngiotensin IIReceptor Blockers(ARB)ACE inhibitorintolerancePregnancy,Bilateral renalartery stenosis,HyperkalaemiaRenal impairmentAlpha-BlockersBenign prostatichypertrophyOrthostatichypotensionBeta-BlockersAngina,Post myocardialinfarctionTachyarrhythmiasHeart failure(low dose)Asthma, chronicobstructivepulmonary disease,Heart blockPeripheral vasculardiseaseCalciumChannel Blockers(dihydropyridine)Elderly patients,Isolated systolichypertensionAngina,Peripheralvascular diseaseCongestive heartfailureCalciumChannel Blockers(rate limiting,e.g. verapamil,diltiazem)Angina Heart block Congestiveheart failure,combination withbeta-blockersThiazide/ thiazidelikeDiureticsHeart failure,Elderly patients,Isolated systolichypertensionGoutDyslipidaemia,Pregnancy,Sexually activemales5 HK <strong>Reference</strong> <strong>Framework</strong> <strong>for</strong> <strong>Hypertension</strong> <strong>Care</strong> <strong>for</strong> Adults in Primary <strong>Care</strong> Settings

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