Nutritional Pathology Topics Nutritional ... - มหาวิทยาลัยนเรศวร
Nutritional Pathology Topics Nutritional ... - มหาวิทยาลัยนเรศวร Nutritional Pathology Topics Nutritional ... - มหาวิทยาลัยนเรศวร
9/7/2012ภาวะทุพโภชนาการ (Malnutrition)Primary malnutrition : missing from the dietSecondary malnutrition : adequate nutrientssupply, but malnutrition may result from- Malabsorption- Impaired nutrient use or storage- Excess nutrient losses- Increased need for nutrients(GI diseases, chronic wasting diseases,acute critical illness)Common Causes• Poverty (homeless, aged, children)• Ignorance(infants, adolescents, pregnant women)• Chronic alcoholism• Acute and chronic illnesses(trauma, burn, cancer, etc.)• Self-imposed dietary restrictionProtein - Energy malnutrition (PEM)- PEM refers to a range of clinicalsyndrome characterized by aninadequate dietary intake of proteinand calories to meet the body’s needs.- Primary (children) and Secondary(illness) PEM- Two polar forms: - Marasmus,- Kwashiorkor A B2
9/7/20121. Marasmus.- Severe reduction in caloric intake- Greater than 60% reduction in body weight- Most common during the first year of life- Use somatic protein component &subcutaneous fat as a source of energy- Serum albumin levels are either normal or onlyslightly reduced- Growth retardation, multivitamin deficiencies,anemia, immune deficiencyMarasmus2. Kwashiorkor- More severe form of malnutrition than marasmus- Mainly occur in children 6 months to 3 years of age- Occurs when protein deprivation is relatively greaterthan the reduction in total calories- Loss of visceral protein component- Hypoalbuminemia → generalized edema- Fatty change of liver- Skin lesion : hypo-and hyperpigmentation,desquamation- Hair change : overall loss of color or alternating band(flag sign), straightening, loss of firm attachment tothe scalp- Multivitamin deficiencies, anemia, immune deficiency3
- Page 4 and 5: 9/7/2012Secondary PEM.SyndromeClini
- Page 6 and 7: 9/7/2012TopicsBulimia• Nutritiona
- Page 8 and 9: 9/7/2012RicketsVitamin DDeficiency
- Page 10 and 11: 9/7/2012Pectus excavatum (Funnel ch
- Page 12 and 13: 9/7/2012Cause of deficiency :-fat m
- Page 14 and 15: 9/7/2012Vitamin B3 (Niacin)- an ess
- Page 16 and 17: 9/7/2012Vitamin C (Ascorbic acid)-F
- Page 18 and 19: 9/7/2012Koilonychiahttp://www.topne
- Page 20 and 21: 9/7/2012Topics??• Nutritional def
- Page 22 and 23: 9/7/2012Exercise more than 3 times
9/7/20121. Marasmus.- Severe reduction in caloric intake- Greater than 60% reduction in body weight- Most common during the first year of life- Use somatic protein component &subcutaneous fat as a source of energy- Serum albumin levels are either normal or onlyslightly reduced- Growth retardation, multivitamin deficiencies,anemia, immune deficiencyMarasmus2. Kwashiorkor- More severe form of malnutrition than marasmus- Mainly occur in children 6 months to 3 years of age- Occurs when protein deprivation is relatively greaterthan the reduction in total calories- Loss of visceral protein component- Hypoalbuminemia → generalized edema- Fatty change of liver- Skin lesion : hypo-and hyperpigmentation,desquamation- Hair change : overall loss of color or alternating band(flag sign), straightening, loss of firm attachment tothe scalp- Multivitamin deficiencies, anemia, immune deficiency3