Nutritional Pathology Topics Nutritional ... - มหาวิทยาลัยนเรศวร
Nutritional Pathology Topics Nutritional ... - มหาวิทยาลัยนเรศวร Nutritional Pathology Topics Nutritional ... - มหาวิทยาลัยนเรศวร
9/7/2012Topics??• Nutritional deficiencies– Protein – Energy Malnutrition– Anorexia Nervosa and Bulimia– Vitamin Deficiencies– Mineral Deficiencies• Obesity• Diet and Systemic DiseasesObesityObesityMesurement : Body mass index (BMI) = Wt (kg)/Ht(m) 2: Body–fat percentage (skin foldmeasurement) and lean body weightBMI : normal = 18.5 – 24.9 kg./m 2: overweight = 25.0 – 29.9 kg./m 2: obesity 30.0 kg./m 2http://www.impactlab.com/wp-content/uploads/2008/09/obese3.jpg20
9/7/2012Neurohumoral mechanism• เปนกลไกการควบคุมการเผาผลาญพลังงาน• Afferent (humoral) signals : leptin(adiposetissue), insulin, ghrelin(stomach)• Hypothalamus (central melanocortin system)• Efferent : feeding behavior + energyexpenditure (TRH and autonomic pathway)Food–derived energy > energy expenditureStorage as triglycerides in adipose tissue (insulin effect)- Daily requirement : 2000 – 3000 kcal/d.- Daily energy expenditure = Basal energy expenditure (BEE)+Activities.BEE man = 66 + (13.7 x Wt.) + (5 x Ht.) – (6.8 x age)BEE woman = 655 + (9.5 x Wt.) + (1.8 x Ht.) – (4.7 x age)Wt (Kg), Ht (cm.), Age (yrs)Factors contributing toobesity :1. Genetic predisposition2. Decreased lipid utitization : aging,defective thermogenesis, inactivity,underexcercising3. Sociocultural environment : stress,emotional, disturbances4. Diseases : hypothalamic disorder.: hypothyroidism.: Cushing’s syndrome.: Polycystic ovary syndrome.21
- Page 2 and 3: 9/7/2012ภาวะทุพโภ
- Page 4 and 5: 9/7/2012Secondary PEM.SyndromeClini
- Page 6 and 7: 9/7/2012TopicsBulimia• Nutritiona
- Page 8 and 9: 9/7/2012RicketsVitamin DDeficiency
- Page 10 and 11: 9/7/2012Pectus excavatum (Funnel ch
- Page 12 and 13: 9/7/2012Cause of deficiency :-fat m
- Page 14 and 15: 9/7/2012Vitamin B3 (Niacin)- an ess
- Page 16 and 17: 9/7/2012Vitamin C (Ascorbic acid)-F
- Page 18 and 19: 9/7/2012Koilonychiahttp://www.topne
- Page 22 and 23: 9/7/2012Exercise more than 3 times
9/7/2012<strong>Topics</strong>??• <strong>Nutritional</strong> deficiencies– Protein – Energy Malnutrition– Anorexia Nervosa and Bulimia– Vitamin Deficiencies– Mineral Deficiencies• Obesity• Diet and Systemic DiseasesObesityObesityMesurement : Body mass index (BMI) = Wt (kg)/Ht(m) 2: Body–fat percentage (skin foldmeasurement) and lean body weightBMI : normal = 18.5 – 24.9 kg./m 2: overweight = 25.0 – 29.9 kg./m 2: obesity 30.0 kg./m 2http://www.impactlab.com/wp-content/uploads/2008/09/obese3.jpg20