Nutritional Pathology Topics Nutritional ... - มหาวิทยาลัยนเรศวร

Nutritional Pathology Topics Nutritional ... - มหาวิทยาลัยนเรศวร Nutritional Pathology Topics Nutritional ... - มหาวิทยาลัยนเรศวร

13.07.2015 Views

9/7/2012Topics??• Nutritional deficiencies– Protein – Energy Malnutrition– Anorexia Nervosa and Bulimia– Vitamin Deficiencies– Mineral Deficiencies• Obesity• Diet and Systemic DiseasesObesityObesityMesurement : Body mass index (BMI) = Wt (kg)/Ht(m) 2: Body–fat percentage (skin foldmeasurement) and lean body weightBMI : normal = 18.5 – 24.9 kg./m 2: overweight = 25.0 – 29.9 kg./m 2: obesity 30.0 kg./m 2http://www.impactlab.com/wp-content/uploads/2008/09/obese3.jpg20

9/7/2012Neurohumoral mechanism• เปนกลไกการควบคุมการเผาผลาญพลังงาน• Afferent (humoral) signals : leptin(adiposetissue), insulin, ghrelin(stomach)• Hypothalamus (central melanocortin system)• Efferent : feeding behavior + energyexpenditure (TRH and autonomic pathway)Food–derived energy > energy expenditureStorage as triglycerides in adipose tissue (insulin effect)- Daily requirement : 2000 – 3000 kcal/d.- Daily energy expenditure = Basal energy expenditure (BEE)+Activities.BEE man = 66 + (13.7 x Wt.) + (5 x Ht.) – (6.8 x age)BEE woman = 655 + (9.5 x Wt.) + (1.8 x Ht.) – (4.7 x age)Wt (Kg), Ht (cm.), Age (yrs)Factors contributing toobesity :1. Genetic predisposition2. Decreased lipid utitization : aging,defective thermogenesis, inactivity,underexcercising3. Sociocultural environment : stress,emotional, disturbances4. Diseases : hypothalamic disorder.: hypothyroidism.: Cushing’s syndrome.: Polycystic ovary syndrome.21

9/7/2012<strong>Topics</strong>??• <strong>Nutritional</strong> deficiencies– Protein – Energy Malnutrition– Anorexia Nervosa and Bulimia– Vitamin Deficiencies– Mineral Deficiencies• Obesity• Diet and Systemic DiseasesObesityObesityMesurement : Body mass index (BMI) = Wt (kg)/Ht(m) 2: Body–fat percentage (skin foldmeasurement) and lean body weightBMI : normal = 18.5 – 24.9 kg./m 2: overweight = 25.0 – 29.9 kg./m 2: obesity 30.0 kg./m 2http://www.impactlab.com/wp-content/uploads/2008/09/obese3.jpg20

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