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GABA - Molecular Devices

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PatchXpress assays - detection of BDZ site antagonists200IC 50= 28 3 nM (n = 5-7)Control current amplitudesPercentage increase in <strong>GABA</strong> response180160140120100806040200Current (nA)3.53.02.52.01.51.00.5(number of cells shown in brackets)(7)(7)-201E-3 0.01 0.1 1 100.01 M <strong>GABA</strong> 1 M Diazepam[Flumazenil ] MMean amplitudes of EC20 <strong>GABA</strong> and1 M diazepam

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